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Stock Comparison

ABCL vs SEER vs TWST vs RXRX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ABCL
AbCellera Biologics Inc.

Biotechnology

HealthcareNASDAQ • CA
Market Cap$1.45B
5Y Perf.-81.9%
SEER
Seer, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$105M
5Y Perf.-96.3%
TWST
Twist Bioscience Corporation

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$3.65B
5Y Perf.-56.4%
RXRX
Recursion Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.46B
5Y Perf.-90.2%

ABCL vs SEER vs TWST vs RXRX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ABCL logoABCL
SEER logoSEER
TWST logoTWST
RXRX logoRXRX
IndustryBiotechnologyBiotechnologyMedical - Diagnostics & ResearchBiotechnology
Market Cap$1.45B$105M$3.65B$1.46B
Revenue (TTM)$75M$16M$409M$66M
Net Income (TTM)$-146M$-79M$-81M$-560M
Gross Margin-48.2%40.7%52.1%-34.4%
Operating Margin-402.1%-5.2%-33.9%-8.8%
Total Debt$137M$26M$137M$78M
Cash & Equiv.$129M$41M$183M$743M

ABCL vs SEER vs TWST vs RXRXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ABCL
SEER
TWST
RXRX
StockApr 21May 26Return
AbCellera Biologics… (ABCL)10018.1-81.9%
Seer, Inc. (SEER)1003.7-96.3%
Twist Bioscience Co… (TWST)10043.6-56.4%
Recursion Pharmaceu… (RXRX)1009.8-90.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ABCL vs SEER vs TWST vs RXRX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ABCL and TWST are tied at the top with 2 categories each — the right choice depends on your priorities. Twist Bioscience Corporation is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. SEER also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
ABCL
AbCellera Biologics Inc.
The Growth Leader

ABCL carries the broadest edge in this set and is the clearest fit for growth and momentum.

  • 160.6% revenue growth vs SEER's -8.1%
  • +139.8% vs RXRX's -22.0%
Best for: growth and momentum
SEER
Seer, Inc.
The Income Pick

SEER is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • beta 0.84
  • Lower volatility, beta 0.84, Low D/E 7.9%, current ratio 16.53x
  • Beta 0.84, current ratio 16.53x
  • Beta 0.84 vs RXRX's 3.18
Best for: income & stability and sleep-well-at-night
TWST
Twist Bioscience Corporation
The Long-Run Compounder

TWST is the #2 pick in this set and the best alternative if long-term compounding is your priority.

  • 318.1% 10Y total return vs RXRX's -81.8%
  • -19.8% margin vs RXRX's -8.4%
  • -12.5% ROA vs RXRX's -40.6%, ROIC -26.9% vs -95.8%
Best for: long-term compounding
RXRX
Recursion Pharmaceuticals, Inc.
The Growth Play

RXRX is the clearest fit if your priority is growth exposure.

  • Rev growth 26.9%, EPS growth 14.8%, 3Y rev CAGR 23.5%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthABCL logoABCL160.6% revenue growth vs SEER's -8.1%
Quality / MarginsTWST logoTWST-19.8% margin vs RXRX's -8.4%
Stability / SafetySEER logoSEERBeta 0.84 vs RXRX's 3.18
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)ABCL logoABCL+139.8% vs RXRX's -22.0%
Efficiency (ROA)TWST logoTWST-12.5% ROA vs RXRX's -40.6%, ROIC -26.9% vs -95.8%

ABCL vs SEER vs TWST vs RXRX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ABCLAbCellera Biologics Inc.
FY 2025
License
62.5%$47M
Research Fees
36.2%$27M
Milestone Payments
1.3%$1M
SEERSeer, Inc.
FY 2023
Grant
100.0%$1M
TWSTTwist Bioscience Corporation
FY 2025
Ngs Tools
55.3%$208M
Synthetic Genes
30.2%$114M
Antibody Discovery
6.2%$23M
Oligo Pools
5.4%$20M
Dna And Biopharma Libraries
3.0%$11M
RXRXRecursion Pharmaceuticals, Inc.
FY 2025
License and Service
99.4%$74M
Grant
0.6%$425,000

ABCL vs SEER vs TWST vs RXRX — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLTWSTLAGGINGRXRX

Income & Cash Flow (Last 12 Months)

TWST leads this category, winning 4 of 6 comparable metrics.

TWST is the larger business by revenue, generating $409M annually — 25.1x SEER's $16M. Profitability is closely matched — net margins range from -19.8% (TWST) to -8.4% (RXRX). On growth, ABCL holds the edge at +7.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
RevenueTrailing 12 months$75M$16M$409M$66M
EBITDAEarnings before interest/tax-$280M-$76M-$115M-$521M
Net IncomeAfter-tax profit-$146M-$79M-$81M-$560M
Free Cash FlowCash after capex-$174M-$46M-$95M-$326M
Gross MarginGross profit ÷ Revenue-48.2%+40.7%+52.1%-34.4%
Operating MarginEBIT ÷ Revenue-4.0%-5.2%-33.9%-8.8%
Net MarginNet income ÷ Revenue-194.9%-4.9%-19.8%-8.4%
FCF MarginFCF ÷ Revenue-2.3%-2.8%-23.2%-4.9%
Rev. Growth (YoY)Latest quarter vs prior year+7.9%+4.5%+19.3%-56.1%
EPS Growth (YoY)Latest quarter vs prior year+75.0%+8.6%-7.6%+56.0%
TWST leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

SEER leads this category, winning 2 of 3 comparable metrics.
MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
Market CapShares × price$1.4B$105M$3.6B$1.5B
Enterprise ValueMkt cap + debt − cash$1.5B$90M$3.6B$797M
Trailing P/EPrice ÷ TTM EPS-9.84x-1.35x-45.03x-2.27x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue19.29x7.52x9.68x19.58x
Price / BookPrice ÷ Book value/share1.49x0.36x7.40x1.29x
Price / FCFMarket cap ÷ FCF
SEER leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

ABCL leads this category, winning 4 of 9 comparable metrics.

ABCL delivers a -15.1% return on equity — every $100 of shareholder capital generates $-15 in annual profit, vs $-54 for RXRX. RXRX carries lower financial leverage with a 0.07x debt-to-equity ratio, signaling a more conservative balance sheet compared to TWST's 0.29x. On the Piotroski fundamental quality scale (0–9), SEER scores 4/9 vs ABCL's 3/9, reflecting mixed financial health.

MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
ROE (TTM)Return on equity-15.1%-29.2%-17.5%-54.3%
ROA (TTM)Return on assets-23.3%-25.7%-12.5%-40.6%
ROICReturn on invested capital-16.8%-21.3%-26.9%-95.8%
ROCEReturn on capital employed-23.5%-25.9%-24.9%-50.1%
Piotroski ScoreFundamental quality 0–93444
Debt / EquityFinancial leverage0.14x0.08x0.29x0.07x
Net DebtTotal debt minus cash$9M-$15M-$46M-$665M
Cash & Equiv.Liquid assets$129M$41M$183M$743M
Total DebtShort + long-term debt$137M$26M$137M$78M
Interest CoverageEBIT ÷ Interest expense-9.52x-336.46x
ABCL leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

TWST leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in TWST five years ago would be worth $5,015 today (with dividends reinvested), compared to $494 for SEER. Over the past 12 months, ABCL leads with a +139.8% total return vs RXRX's -22.0%. The 3-year compound annual growth rate (CAGR) favors TWST at 63.5% vs SEER's -19.2% — a key indicator of consistent wealth creation.

MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
YTD ReturnYear-to-date+40.5%+3.3%+80.7%-22.1%
1-Year ReturnPast 12 months+139.8%+1.6%+78.6%-22.0%
3-Year ReturnCumulative with dividends-15.6%-47.2%+336.9%-41.6%
5-Year ReturnCumulative with dividends-83.4%-95.1%-49.9%-88.2%
10-Year ReturnCumulative with dividends-91.8%-96.7%+318.1%-81.8%
CAGR (3Y)Annualised 3-year return-5.5%-19.2%+63.5%-16.4%
TWST leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

Evenly matched — SEER and TWST each lead in 1 of 2 comparable metrics.

SEER is the less volatile stock with a 0.84 beta — it tends to amplify market swings less than RXRX's 3.18 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. TWST currently trades 88.7% from its 52-week high vs RXRX's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
Beta (5Y)Sensitivity to S&P 5002.31x0.84x2.47x3.18x
52-Week HighHighest price in past year$6.52$2.41$66.00$7.18
52-Week LowLowest price in past year$1.94$1.65$23.30$2.80
% of 52W HighCurrent price vs 52-week peak+73.9%+78.0%+88.7%+45.5%
RSI (14)Momentum oscillator 0–10077.549.857.049.5
Avg Volume (50D)Average daily shares traded4.5M401K1.2M12.5M
Evenly matched — SEER and TWST each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: ABCL as "Buy", SEER as "Hold", TWST as "Buy", RXRX as "Hold". Consensus price targets imply 318.5% upside for ABCL (target: $20) vs -15.4% for TWST (target: $50).

MetricABCL logoABCLAbCellera Biologi…SEER logoSEERSeer, Inc.TWST logoTWSTTwist Bioscience …RXRX logoRXRXRecursion Pharmac…
Analyst RatingConsensus buy/hold/sellBuyHoldBuyHold
Price TargetConsensus 12-month target$20.17$49.50$11.00
# AnalystsCovering analysts1141310
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%+11.3%+0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

TWST leads in 2 of 6 categories (Income & Cash Flow, Total Returns). SEER leads in 1 (Valuation Metrics). 1 tied.

Best OverallTwist Bioscience Corporation (TWST)Leads 2 of 6 categories
Loading custom metrics...

ABCL vs SEER vs TWST vs RXRX: Key Questions Answered

8 questions · data-driven answers · updated daily

01

Is ABCL or SEER or TWST or RXRX a better buy right now?

For growth investors, AbCellera Biologics Inc.

(ABCL) is the stronger pick with 160. 6% revenue growth year-over-year, versus -8. 1% for Seer, Inc. (SEER). Analysts rate AbCellera Biologics Inc. (ABCL) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — ABCL or SEER or TWST or RXRX?

Over the past 5 years, Twist Bioscience Corporation (TWST) delivered a total return of -49.

9%, compared to -95. 1% for Seer, Inc. (SEER). Over 10 years, the gap is even starker: TWST returned +318. 1% versus SEER's -96. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — ABCL or SEER or TWST or RXRX?

By beta (market sensitivity over 5 years), Seer, Inc.

(SEER) is the lower-risk stock at 0. 84β versus Recursion Pharmaceuticals, Inc. 's 3. 18β — meaning RXRX is approximately 278% more volatile than SEER relative to the S&P 500. On balance sheet safety, Recursion Pharmaceuticals, Inc. (RXRX) carries a lower debt/equity ratio of 7% versus 29% for Twist Bioscience Corporation — giving it more financial flexibility in a downturn.

04

Which is growing faster — ABCL or SEER or TWST or RXRX?

By revenue growth (latest reported year), AbCellera Biologics Inc.

(ABCL) is pulling ahead at 160. 6% versus -8. 1% for Seer, Inc. (SEER). On earnings-per-share growth, the picture is similar: Twist Bioscience Corporation grew EPS 63. 9% year-over-year, compared to -3. 0% for Seer, Inc.. Over a 3-year CAGR, SEER leads at 29. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — ABCL or SEER or TWST or RXRX?

Twist Bioscience Corporation (TWST) is the more profitable company, earning -20.

6% net margin versus -863. 4% for Recursion Pharmaceuticals, Inc. — meaning it keeps -20. 6% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: TWST leads at -36. 2% versus -867. 9% for RXRX. At the gross margin level — before operating expenses — TWST leads at 50. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Which pays a better dividend — ABCL or SEER or TWST or RXRX?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

07

Is ABCL or SEER or TWST or RXRX better for a retirement portfolio?

For long-horizon retirement investors, Seer, Inc.

(SEER) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 84)). AbCellera Biologics Inc. (ABCL) carries a higher beta of 2. 31 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SEER: -96. 7%, ABCL: -91. 8%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between ABCL and SEER and TWST and RXRX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: ABCL is a small-cap high-growth stock; SEER is a small-cap quality compounder stock; TWST is a small-cap high-growth stock; RXRX is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Revenue Growth > 394%
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  • Market Cap > $100B
  • Gross Margin > 24%
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  • Market Cap > $100B
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  • Sector: Healthcare
  • Market Cap > $100B
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