Biotechnology
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Side-by-side financial analysisStock Comparison
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $210M | $1.89B | $5M | $6.90B | $904M |
| Revenue (TTM) | $103K | $453M | $2M | $0.00 | $93M |
| Net Income (TTM) | $-55M | $-178M | $-51M | $-506M | $-172M |
| Gross Margin | -10.9% | 57.9% | 106.0% | — | 94.4% |
| Operating Margin | -589.5% | -53.5% | -25.2% | — | -144.7% |
| Total Debt | $18M | $224M | $6M | $72K | $188M |
| Cash & Equiv. | $85M | $680M | $7M | $902M | $54M |
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | Jun 26 | Return |
|---|---|---|---|
| Adagene Inc. (ADAG) | 100 | 14.6 | -85.4% |
| Zai Lab Limited (ZLAB) | 100 | 11.6 | -88.4% |
| BioAtla, Inc. (BCAB) | 100 | 0.1 | -99.9% |
| Immunovant, Inc. (IMVT) | 100 | 213.1 | +113.1% |
| Xencor, Inc. (XNCR) | 100 | 25.0 | -75.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ADAG vs ZLAB vs BCAB vs IMVT vs XNCR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ADAG lags the leaders in this set but could rank higher in a more targeted comparison.
ZLAB carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 15.3%, EPS growth 38.5%, 3Y rev CAGR 28.9%
- 15.3% revenue growth vs ADAG's -99.4%
- -15.5% ROA vs BCAB's -309.4%
BCAB ranks third and is worth considering specifically for income & stability.
- beta 0.25
- Beta 0.25 vs XNCR's 1.72
IMVT is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.
- 237.9% 10Y total return vs XNCR's -12.6%
- Lower volatility, beta 1.66, Low D/E 0.0%, current ratio 9.09x
- Beta 1.66, current ratio 9.09x
- 2.6% margin vs ADAG's -537.2%
Among these 5 stocks, XNCR doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 15.3% revenue growth vs ADAG's -99.4% | |
| Quality / Margins | 2.6% margin vs ADAG's -537.2% | |
| Stability / Safety | Beta 0.25 vs XNCR's 1.72 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +110.9% vs BCAB's -82.0% | |
| Efficiency (ROA) | -15.5% ROA vs BCAB's -309.4% |
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ZLAB leads in 1 of 6 categories
XNCR leads 1 • ADAG leads 0 • BCAB leads 0 • IMVT leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ZLAB leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ZLAB and IMVT operate at a comparable scale, with $453M and $0 in trailing revenue. ZLAB is the more profitable business, keeping -39.3% of every revenue dollar as net income compared to ADAG's -537.2%. On growth, ZLAB holds the edge at -6.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $103,204 | $453M | $2M | $0 | $93M |
| EBITDAEarnings before interest/tax | -$59M | -$227M | -$51M | -$532M | -$127M |
| Net IncomeAfter-tax profit | -$55M | -$178M | -$51M | -$506M | -$172M |
| Free Cash FlowCash after capex | -$48M | -$129M | -$23M | -$407M | -$189M |
| Gross MarginGross profit ÷ Revenue | -10.9% | +57.9% | +106.0% | — | +94.4% |
| Operating MarginEBIT ÷ Revenue | -589.5% | -53.5% | -25.2% | — | -144.7% |
| Net MarginNet income ÷ Revenue | -537.2% | -39.3% | -25.3% | — | -185.7% |
| FCF MarginFCF ÷ Revenue | -461.1% | -28.5% | -11.5% | — | -2.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -6.5% | — | — | -100.0% |
| EPS Growth (YoY)Latest quarter vs prior year | -50.0% | -11.1% | +67.5% | -14.1% | -159.1% |
Valuation Metrics
Evenly matched — BCAB and IMVT and XNCR each lead in 1 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $210M | $1.9B | $5M | $6.9B | $904M |
| Enterprise ValueMkt cap + debt − cash | $144M | $1.4B | $4M | $6.0B | $1.0B |
| Trailing P/EPrice ÷ TTM EPS | -3.76x | -10.67x | -0.08x | -12.14x | -9.94x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 2037.00x | 4.11x | 2.43x | — | 7.20x |
| Price / BookPrice ÷ Book value/share | 2.55x | 2.61x | — | 7.19x | 1.44x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
XNCR leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ZLAB delivers a -24.3% return on equity — every $100 of shareholder capital generates $-24 in annual profit, vs $-146 for ADAG. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ADAG's 0.37x. On the Piotroski fundamental quality scale (0–9), ZLAB scores 3/9 vs ADAG's 1/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -146.2% | -24.3% | — | -68.2% | -28.8% |
| ROA (TTM)Return on assets | -83.3% | -15.5% | -3.1% | -62.2% | -20.5% |
| ROICReturn on invested capital | — | -41.7% | — | — | -16.3% |
| ROCEReturn on capital employed | -53.1% | -27.2% | -4.0% | -68.3% | -21.6% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 3 | 2 | 2 | 3 |
| Debt / EquityFinancial leverage | 0.37x | 0.31x | — | 0.00x | 0.30x |
| Net DebtTotal debt minus cash | -$67M | -$455M | -$918,000 | -$902M | $134M |
| Cash & Equiv.Liquid assets | $85M | $680M | $7M | $902M | $54M |
| Total DebtShort + long-term debt | $18M | $224M | $6M | $72,000 | $188M |
| Interest CoverageEBIT ÷ Interest expense | -46.92x | -30.73x | — | — | -0.98x |
Total Returns (Dividends Reinvested)
Evenly matched — ADAG and IMVT each lead in 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $19 for BCAB. Over the past 12 months, IMVT leads with a +110.9% total return vs BCAB's -82.0%. The 3-year compound annual growth rate (CAGR) favors ADAG at 42.3% vs BCAB's -72.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +94.0% | -1.5% | -85.5% | +29.8% | -17.4% |
| 1-Year ReturnPast 12 months | +82.1% | -60.3% | -82.0% | +110.9% | +30.8% |
| 3-Year ReturnCumulative with dividends | +187.9% | -38.2% | -97.9% | +55.0% | -54.5% |
| 5-Year ReturnCumulative with dividends | -73.7% | -90.0% | -99.8% | +213.0% | -67.0% |
| 10-Year ReturnCumulative with dividends | -88.1% | -38.9% | -99.8% | +237.9% | -12.6% |
| CAGR (3Y)Annualised 3-year return | +42.3% | -14.8% | -72.6% | +15.7% | -23.1% |
Risk & Volatility
Evenly matched — BCAB and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
BCAB is the less volatile stock with a 0.25 beta — it tends to amplify market swings less than XNCR's 1.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 92.7% from its 52-week high vs BCAB's 5.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.73x | 1.15x | 0.25x | 1.66x | 1.72x |
| 52-Week HighHighest price in past year | $4.75 | $44.34 | $71.50 | $36.27 | $18.69 |
| 52-Week LowLowest price in past year | $1.30 | $15.96 | $0.33 | $14.32 | $6.92 |
| % of 52W HighCurrent price vs 52-week peak | +75.2% | +38.5% | +5.4% | +92.7% | +66.0% |
| RSI (14)Momentum oscillator 0–100 | 49.9 | 43.4 | 41.6 | 57.9 | 52.9 |
| Avg Volume (50D)Average daily shares traded | 214K | 842K | 45K | 1.9M | 715K |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: ADAG as "Buy", ZLAB as "Buy", BCAB as "Buy", IMVT as "Buy", XNCR as "Buy". Consensus price targets imply 6376.7% upside for BCAB (target: $250) vs 29.9% for IMVT (target: $44).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $5.00 | $35.00 | $250.00 | $43.67 | $26.00 |
| # AnalystsCovering analysts | 5 | 11 | 9 | 23 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | — | — | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
ZLAB leads in 1 of 6 categories (Income & Cash Flow). XNCR leads in 1 (Profitability & Efficiency). 3 tied.
ADAG vs ZLAB vs BCAB vs IMVT vs XNCR: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is ADAG or ZLAB or BCAB or IMVT or XNCR a better buy right now?
For growth investors, Zai Lab Limited (ZLAB) is the stronger pick with 15.
3% revenue growth year-over-year, versus -99. 4% for Adagene Inc. (ADAG). Analysts rate Adagene Inc. (ADAG) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ADAG or ZLAB or BCAB or IMVT or XNCR?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -99. 8% for BioAtla, Inc. (BCAB). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus BCAB's -99. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ADAG or ZLAB or BCAB or IMVT or XNCR?
By beta (market sensitivity over 5 years), BioAtla, Inc.
(BCAB) is the lower-risk stock at 0. 25β versus Xencor, Inc. 's 1. 72β — meaning XNCR is approximately 579% more volatile than BCAB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 37% for Adagene Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — ADAG or ZLAB or BCAB or IMVT or XNCR?
By revenue growth (latest reported year), Zai Lab Limited (ZLAB) is pulling ahead at 15.
3% versus -99. 4% for Adagene Inc. (ADAG). On earnings-per-share growth, the picture is similar: Xencor, Inc. grew EPS 65. 4% year-over-year, compared to -75. 9% for Adagene Inc.. Over a 3-year CAGR, ZLAB leads at 28. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ADAG or ZLAB or BCAB or IMVT or XNCR?
Immunovant, Inc.
(IMVT) is the more profitable company, earning 0. 0% net margin versus -323. 9% for Adagene Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IMVT leads at 0. 0% versus -348. 4% for ADAG. At the gross margin level — before operating expenses — BCAB leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — ADAG or ZLAB or BCAB or IMVT or XNCR?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is ADAG or ZLAB or BCAB or IMVT or XNCR better for a retirement portfolio?
For long-horizon retirement investors, BioAtla, Inc.
(BCAB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 25)). Xencor, Inc. (XNCR) carries a higher beta of 1. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BCAB: -99. 8%, XNCR: -12. 6%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between ADAG and ZLAB and BCAB and IMVT and XNCR?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ADAG is a small-cap quality compounder stock; ZLAB is a small-cap high-growth stock; BCAB is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; XNCR is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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