Biotechnology
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4 / 10Stock Comparison
ATHA vs LLY vs BIIB vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Medical - Diagnostics & Research
ATHA vs LLY vs BIIB vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Medical - Diagnostics & Research |
| Market Cap | $17M | $921.16B | $28.25B | $30.32B |
| Revenue (TTM) | $0.00 | $72.25B | $9.86B | $16.63B |
| Net Income (TTM) | $-129M | $25.27B | $1.37B | $1.39B |
| Gross Margin | — | 83.5% | 69.8% | 26.1% |
| Operating Margin | — | 45.9% | 15.6% | 13.9% |
| Forward P/E | — | 28.2x | 13.0x | 14.1x |
| Total Debt | $803K | $42.50B | $6.95B | $16.17B |
| Cash & Equiv. | $69M | $7.16B | $3.01B | $1.98B |
ATHA vs LLY vs BIIB vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 20 | Feb 26 | Return |
|---|---|---|---|
| Athira Pharma, Inc. (ATHA) | 100 | 2.4 | -97.6% |
| Eli Lilly and Compa… (LLY) | 100 | 700.7 | +600.7% |
| Biogen Inc. (BIIB) | 100 | 63.4 | -36.6% |
| IQVIA Holdings Inc. (IQV) | 100 | 146.0 | +46.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ATHA vs LLY vs BIIB vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ATHA is the clearest fit if your priority is momentum.
- +81.6% vs IQV's +16.5%
LLY carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 11 yrs, beta 0.71, yield 0.6%
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 12.4% 10Y total return vs IQV's 166.5%
- 44.7% revenue growth vs ATHA's -64.6%
BIIB is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 0.64, Low D/E 38.1%, current ratio 2.68x
- Beta 0.64, current ratio 2.68x
- Lower P/E (13.0x vs 28.2x)
- Beta 0.64 vs ATHA's 1.47
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.35 vs LLY's 0.98
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs ATHA's -64.6% | |
| Value | Lower P/E (13.0x vs 28.2x) | |
| Quality / Margins | 35.0% margin vs IQV's 8.3% | |
| Stability / Safety | Beta 0.64 vs ATHA's 1.47 | |
| Dividends | 0.6% yield; 11-year raise streak; the other 3 pay no meaningful dividend | |
| Momentum (1Y) | +81.6% vs IQV's +16.5% | |
| Efficiency (ROA) | 22.7% ROA vs ATHA's -225.7% |
ATHA vs LLY vs BIIB vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ATHA vs LLY vs BIIB vs IQV — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 4 of 6 categories
BIIB leads 2 • ATHA leads 0 • IQV leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 5 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY and ATHA operate at a comparable scale, with $72.2B and $0 in trailing revenue. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to IQV's 8.3%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $72.2B | $9.9B | $16.6B |
| EBITDAEarnings before interest/tax | -$110M | $34.7B | $2.4B | $3.5B |
| Net IncomeAfter-tax profit | -$129M | $25.3B | $1.4B | $1.4B |
| Free Cash FlowCash after capex | -$52M | $13.6B | $2.6B | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | +83.5% | +69.8% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | +45.9% | +15.6% | +13.9% |
| Net MarginNet income ÷ Revenue | — | +35.0% | +13.9% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | +18.8% | +26.6% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% | +1.9% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +24.8% | +169.9% | +31.1% | +15.0% |
Valuation Metrics
BIIB leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 21.7x trailing earnings, BIIB trades at a 49% valuation discount to LLY's 42.5x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs LLY's 1.47x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $17M | $921.2B | $28.3B | $30.3B |
| Enterprise ValueMkt cap + debt − cash | -$30M | $956.5B | $32.2B | $44.5B |
| Trailing P/EPrice ÷ TTM EPS | -0.17x | 42.48x | 21.67x | 22.79x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 28.24x | 13.05x | 14.06x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.47x | — | 0.56x |
| EV / EBITDAEnterprise value multiple | — | 30.60x | 11.45x | 12.97x |
| Price / SalesMarket cap ÷ Revenue | — | 14.13x | 2.88x | 1.86x |
| Price / BookPrice ÷ Book value/share | 0.37x | 32.99x | 1.54x | 4.67x |
| Price / FCFMarket cap ÷ FCF | — | 102.67x | 13.78x | 14.78x |
Profitability & Efficiency
LLY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-4 for ATHA. ATHA carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs ATHA's 2/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -3.8% | +101.2% | +7.5% | +22.1% |
| ROA (TTM)Return on assets | -2.3% | +22.7% | +4.7% | +4.7% |
| ROICReturn on invested capital | — | +41.8% | +6.5% | +8.7% |
| ROCEReturn on capital employed | -2.3% | +46.6% | +7.7% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 8 | 5 | 4 |
| Debt / EquityFinancial leverage | 0.03x | 1.60x | 0.38x | 2.44x |
| Net DebtTotal debt minus cash | -$68M | $35.3B | $3.9B | $14.2B |
| Cash & Equiv.Liquid assets | $69M | $7.2B | $3.0B | $2.0B |
| Total DebtShort + long-term debt | $803,000 | $42.5B | $6.9B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 6.91x | 3.10x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,115 today (with dividends reinvested), compared to $235 for ATHA. Over the past 12 months, ATHA leads with a +81.6% total return vs IQV's +16.5%. The 3-year compound annual growth rate (CAGR) favors LLY at 31.8% vs ATHA's -46.7% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -37.6% | -9.6% | +7.6% | -20.7% |
| 1-Year ReturnPast 12 months | +81.6% | +26.3% | +63.3% | +16.5% |
| 3-Year ReturnCumulative with dividends | -84.8% | +129.1% | -39.1% | -5.9% |
| 5-Year ReturnCumulative with dividends | -97.7% | +411.1% | -30.2% | -23.8% |
| 10-Year ReturnCumulative with dividends | -97.5% | +1237.7% | -29.2% | +166.5% |
| CAGR (3Y)Annualised 3-year return | -46.7% | +31.8% | -15.2% | -2.0% |
Risk & Volatility
BIIB leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
BIIB is the less volatile stock with a 0.64 beta — it tends to amplify market swings less than ATHA's 1.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. BIIB currently trades 94.6% from its 52-week high vs ATHA's 51.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.47x | 0.71x | 0.64x | 1.33x |
| 52-Week HighHighest price in past year | $8.36 | $1133.95 | $202.41 | $247.05 |
| 52-Week LowLowest price in past year | $2.30 | $623.78 | $115.25 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +51.9% | +86.0% | +94.6% | +72.3% |
| RSI (14)Momentum oscillator 0–100 | 38.4 | 61.4 | 56.6 | 58.5 |
| Avg Volume (50D)Average daily shares traded | 46K | 2.6M | 1.0M | 1.6M |
Analyst Outlook
LLY leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: LLY as "Buy", BIIB as "Buy", IQV as "Buy". Consensus price targets imply 29.1% upside for LLY (target: $1258) vs 10.5% for BIIB (target: $211). LLY is the only dividend payer here at 0.61% yield — a key consideration for income-focused portfolios.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $1258.47 | $211.42 | $225.63 |
| # AnalystsCovering analysts | — | 45 | 48 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | +0.6% | — | — |
| Dividend StreakConsecutive years of raises | — | 11 | 0 | 2 |
| Dividend / ShareAnnual DPS | — | $6.00 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | 0.0% | +4.1% |
LLY leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). BIIB leads in 2 (Valuation Metrics, Risk & Volatility).
ATHA vs LLY vs BIIB vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ATHA or LLY or BIIB or IQV a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus 1. 4% for Biogen Inc. (BIIB). Biogen Inc. (BIIB) offers the better valuation at 21. 7x trailing P/E (13. 0x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ATHA or LLY or BIIB or IQV?
On trailing P/E, Biogen Inc.
(BIIB) is the cheapest at 21. 7x versus Eli Lilly and Company at 42. 5x. On forward P/E, Biogen Inc. is actually cheaper at 13. 0x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus Eli Lilly and Company's 0. 98x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — ATHA or LLY or BIIB or IQV?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +411.
1%, compared to -97. 7% for Athira Pharma, Inc. (ATHA). Over 10 years, the gap is even starker: LLY returned +1238% versus ATHA's -97. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ATHA or LLY or BIIB or IQV?
By beta (market sensitivity over 5 years), Biogen Inc.
(BIIB) is the lower-risk stock at 0. 64β versus Athira Pharma, Inc. 's 1. 47β — meaning ATHA is approximately 130% more volatile than BIIB relative to the S&P 500. On balance sheet safety, Athira Pharma, Inc. (ATHA) carries a lower debt/equity ratio of 3% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — ATHA or LLY or BIIB or IQV?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus 1. 4% for Biogen Inc. (BIIB). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -21. 1% for Biogen Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ATHA or LLY or BIIB or IQV?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus 0. 0% for Athira Pharma, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 0. 0% for ATHA. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ATHA or LLY or BIIB or IQV more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus Eli Lilly and Company's 0. 98x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Biogen Inc. (BIIB) trades at 13. 0x forward P/E versus 28. 2x for Eli Lilly and Company — 15. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LLY: 29. 1% to $1258. 47.
08Which pays a better dividend — ATHA or LLY or BIIB or IQV?
In this comparison, LLY (0.
6% yield) pays a dividend. ATHA, BIIB, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is ATHA or LLY or BIIB or IQV better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
71), 0. 6% yield, +1238% 10Y return). Both have compounded well over 10 years (LLY: +1238%, ATHA: -97. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ATHA and LLY and BIIB and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ATHA is a small-cap quality compounder stock; LLY is a large-cap high-growth stock; BIIB is a mid-cap quality compounder stock; IQV is a mid-cap quality compounder stock. LLY pays a dividend while ATHA, BIIB, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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