Medical - Healthcare Information Services
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5 / 10Stock Comparison
CERT vs LLY vs PFE vs IQV vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Medical - Diagnostics & Research
Medical - Diagnostics & Research
CERT vs LLY vs PFE vs IQV vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Medical - Healthcare Information Services | Drug Manufacturers - General | Drug Manufacturers - General | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $1.03B | $921.16B | $150.63B | $30.32B | $8.98B |
| Revenue (TTM) | $419M | $72.25B | $63.31B | $16.63B | $4.03B |
| Net Income (TTM) | $-2M | $25.27B | $7.49B | $1.39B | $-185M |
| Gross Margin | 61.5% | 83.5% | 69.3% | 26.1% | 24.9% |
| Operating Margin | 5.0% | 45.9% | 23.4% | 13.9% | 11.8% |
| Forward P/E | 14.1x | 28.2x | 8.9x | 14.1x | 16.4x |
| Total Debt | $11M | $42.50B | $67.42B | $16.17B | $3.07B |
| Cash & Equiv. | $189M | $7.16B | $1.14B | $1.98B | $214M |
CERT vs LLY vs PFE vs IQV vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Dec 20 | May 26 | Return |
|---|---|---|---|
| Certara, Inc. (CERT) | 100 | 18.7 | -81.3% |
| Eli Lilly and Compa… (LLY) | 100 | 577.4 | +477.4% |
| Pfizer Inc. (PFE) | 100 | 71.9 | -28.1% |
| IQVIA Holdings Inc. (IQV) | 100 | 99.7 | -0.3% |
| Charles River Labor… (CRL) | 100 | 72.8 | -27.2% |
Price return only. Dividends and distributions are not included.
Quick Verdict: CERT vs LLY vs PFE vs IQV vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
CERT is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.21, Low D/E 1.1%, current ratio 2.05x
LLY carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 12.4% 10Y total return vs IQV's 166.5%
- 44.7% revenue growth vs PFE's -1.6%
- 35.0% margin vs CRL's -4.6%
PFE is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 15 yrs, beta 0.54, yield 6.5%
- Beta 0.54, yield 6.5%, current ratio 1.16x
- Lower P/E (8.9x vs 16.4x)
- Beta 0.54 vs CRL's 1.52, lower leverage
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.35 vs LLY's 0.98
CRL ranks third and is worth considering specifically for momentum.
- +32.8% vs CERT's -44.9%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs PFE's -1.6% | |
| Value | Lower P/E (8.9x vs 16.4x) | |
| Quality / Margins | 35.0% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.54 vs CRL's 1.52, lower leverage | |
| Dividends | 6.5% yield, 15-year raise streak, vs LLY's 0.6%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +32.8% vs CERT's -44.9% | |
| Efficiency (ROA) | 22.7% ROA vs CRL's -2.5%, ROIC 41.8% vs 6.3% |
CERT vs LLY vs PFE vs IQV vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
CERT vs LLY vs PFE vs IQV vs CRL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 3 of 6 categories
PFE leads 2 • CERT leads 1 • IQV leads 0 • CRL leads 0
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 6 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY is the larger business by revenue, generating $72.2B annually — 172.5x CERT's $419M. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to CRL's -4.6%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $419M | $72.2B | $63.3B | $16.6B | $4.0B |
| EBITDAEarnings before interest/tax | $78M | $34.7B | $21.0B | $3.5B | $757M |
| Net IncomeAfter-tax profit | -$2M | $25.3B | $7.5B | $1.4B | -$185M |
| Free Cash FlowCash after capex | $67M | $13.6B | $9.5B | $2.7B | $391M |
| Gross MarginGross profit ÷ Revenue | +61.5% | +83.5% | +69.3% | +26.1% | +24.9% |
| Operating MarginEBIT ÷ Revenue | +5.0% | +45.9% | +23.4% | +13.9% | +11.8% |
| Net MarginNet income ÷ Revenue | -0.4% | +35.0% | +11.8% | +8.3% | -4.6% |
| FCF MarginFCF ÷ Revenue | +15.9% | +18.8% | +15.0% | +16.1% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | +3.3% | +55.5% | +5.4% | +8.4% | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | -191.0% | +169.9% | -9.5% | +15.0% | -160.0% |
Valuation Metrics
CERT leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 19.5x trailing earnings, PFE trades at a 54% valuation discount to LLY's 42.5x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs LLY's 1.47x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.0B | $921.2B | $150.6B | $30.3B | $9.0B |
| Enterprise ValueMkt cap + debt − cash | $857M | $956.5B | $216.9B | $44.5B | $11.8B |
| Trailing P/EPrice ÷ TTM EPS | -631.00x | 42.48x | 19.47x | 22.79x | -62.52x |
| Forward P/EPrice ÷ next-FY EPS est. | 14.10x | 28.24x | 8.94x | 14.06x | 16.42x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.47x | — | 0.56x | — |
| EV / EBITDAEnterprise value multiple | 11.05x | 30.60x | 10.66x | 12.97x | 12.98x |
| Price / SalesMarket cap ÷ Revenue | 2.47x | 14.13x | 2.41x | 1.86x | 2.24x |
| Price / BookPrice ÷ Book value/share | 0.95x | 32.99x | 1.74x | 4.67x | 2.81x |
| Price / FCFMarket cap ÷ FCF | 10.94x | 102.67x | 16.60x | 14.78x | 17.31x |
Profitability & Efficiency
LLY leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-6 for CRL. CERT carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs CRL's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -0.2% | +101.2% | +8.3% | +22.1% | -5.7% |
| ROA (TTM)Return on assets | -0.1% | +22.7% | +3.6% | +4.7% | -2.5% |
| ROICReturn on invested capital | +1.5% | +41.8% | +7.5% | +8.7% | +6.3% |
| ROCEReturn on capital employed | +1.5% | +46.6% | +9.0% | +11.0% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 8 | 7 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.01x | 1.60x | 0.78x | 2.44x | 0.95x |
| Net DebtTotal debt minus cash | -$178M | $35.3B | $66.3B | $14.2B | $2.9B |
| Cash & Equiv.Liquid assets | $189M | $7.2B | $1.1B | $2.0B | $214M |
| Total DebtShort + long-term debt | $11M | $42.5B | $67.4B | $16.2B | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 4.02x | 3.10x | 6.38x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,115 today (with dividends reinvested), compared to $2,141 for CERT. Over the past 12 months, CRL leads with a +32.8% total return vs CERT's -44.9%. The 3-year compound annual growth rate (CAGR) favors LLY at 31.8% vs CERT's -35.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -27.8% | -9.6% | +6.9% | -20.7% | -10.1% |
| 1-Year ReturnPast 12 months | -44.9% | +26.3% | +23.7% | +16.5% | +32.8% |
| 3-Year ReturnCumulative with dividends | -73.1% | +129.1% | -18.4% | -5.9% | -4.2% |
| 5-Year ReturnCumulative with dividends | -78.6% | +411.1% | -13.3% | -23.8% | -46.9% |
| 10-Year ReturnCumulative with dividends | -83.4% | +1237.7% | +29.6% | +166.5% | +119.2% |
| CAGR (3Y)Annualised 3-year return | -35.4% | +31.8% | -6.6% | -2.0% | -1.4% |
Risk & Volatility
PFE leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
PFE is the less volatile stock with a 0.54 beta — it tends to amplify market swings less than CRL's 1.52 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PFE currently trades 92.1% from its 52-week high vs CERT's 45.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.21x | 0.71x | 0.54x | 1.33x | 1.52x |
| 52-Week HighHighest price in past year | $13.88 | $1133.95 | $28.75 | $247.05 | $228.88 |
| 52-Week LowLowest price in past year | $5.19 | $623.78 | $21.97 | $134.65 | $131.30 |
| % of 52W HighCurrent price vs 52-week peak | +45.5% | +86.0% | +92.1% | +72.3% | +79.5% |
| RSI (14)Momentum oscillator 0–100 | 53.5 | 61.4 | 44.2 | 58.5 | 57.2 |
| Avg Volume (50D)Average daily shares traded | 3.5M | 2.6M | 33.3M | 1.6M | 806K |
Analyst Outlook
PFE leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: CERT as "Buy", LLY as "Buy", PFE as "Hold", IQV as "Buy", CRL as "Buy". Consensus price targets imply 58.5% upside for CERT (target: $10) vs 3.0% for PFE (target: $27). For income investors, PFE offers the higher dividend yield at 6.49% vs LLY's 0.61%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $10.00 | $1258.47 | $27.27 | $225.63 | $205.43 |
| # AnalystsCovering analysts | 14 | 45 | 39 | 44 | 36 |
| Dividend YieldAnnual dividend ÷ price | — | +0.6% | +6.5% | — | — |
| Dividend StreakConsecutive years of raises | — | 11 | 15 | 2 | 1 |
| Dividend / ShareAnnual DPS | — | $6.00 | $1.72 | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +4.1% | +0.4% | 0.0% | +4.1% | +4.0% |
LLY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PFE leads in 2 (Risk & Volatility, Analyst Outlook).
CERT vs LLY vs PFE vs IQV vs CRL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is CERT or LLY or PFE or IQV or CRL a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus -1. 6% for Pfizer Inc. (PFE). Pfizer Inc. (PFE) offers the better valuation at 19. 5x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate Certara, Inc. (CERT) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — CERT or LLY or PFE or IQV or CRL?
On trailing P/E, Pfizer Inc.
(PFE) is the cheapest at 19. 5x versus Eli Lilly and Company at 42. 5x. On forward P/E, Pfizer Inc. is actually cheaper at 8. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus Eli Lilly and Company's 0. 98x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — CERT or LLY or PFE or IQV or CRL?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +411.
1%, compared to -78. 6% for Certara, Inc. (CERT). Over 10 years, the gap is even starker: LLY returned +1238% versus CERT's -83. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — CERT or LLY or PFE or IQV or CRL?
By beta (market sensitivity over 5 years), Pfizer Inc.
(PFE) is the lower-risk stock at 0. 54β versus Charles River Laboratories International, Inc. 's 1. 52β — meaning CRL is approximately 179% more volatile than PFE relative to the S&P 500. On balance sheet safety, Certara, Inc. (CERT) carries a lower debt/equity ratio of 1% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — CERT or LLY or PFE or IQV or CRL?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus -1. 6% for Pfizer Inc. (PFE). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — CERT or LLY or PFE or IQV or CRL?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 5. 0% for CERT. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is CERT or LLY or PFE or IQV or CRL more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus Eli Lilly and Company's 0. 98x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Pfizer Inc. (PFE) trades at 8. 9x forward P/E versus 28. 2x for Eli Lilly and Company — 19. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CERT: 58. 5% to $10. 00.
08Which pays a better dividend — CERT or LLY or PFE or IQV or CRL?
In this comparison, PFE (6.
5% yield), LLY (0. 6% yield) pay a dividend. CERT, IQV, CRL do not pay a meaningful dividend and should not be held primarily for income.
09Is CERT or LLY or PFE or IQV or CRL better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
71), 0. 6% yield, +1238% 10Y return). Charles River Laboratories International, Inc. (CRL) carries a higher beta of 1. 52 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LLY: +1238%, CRL: +119. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between CERT and LLY and PFE and IQV and CRL?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: CERT is a small-cap quality compounder stock; LLY is a large-cap high-growth stock; PFE is a mid-cap income-oriented stock; IQV is a mid-cap quality compounder stock; CRL is a small-cap quality compounder stock. LLY, PFE pay a dividend while CERT, IQV, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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