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Stock Comparison

CRIS vs DBVT vs IMVT vs AGEN

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CRIS
Curis, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$76M
5Y Perf.-96.5%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-58.8%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+6.1%
AGEN
Agenus Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$132M
5Y Perf.-95.0%

CRIS vs DBVT vs IMVT vs AGEN — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CRIS logoCRIS
DBVT logoDBVT
IMVT logoIMVT
AGEN logoAGEN
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$76M$1712.35T$5.53B$132M
Revenue (TTM)$9M$0.00$0.00$114M
Net Income (TTM)$-8M$-168M$-464M$115K
Gross Margin99.5%35.7%
Operating Margin-348.4%-17.7%
Forward P/E1.8x
Total Debt$2M$22M$98K$10M
Cash & Equiv.$5M$194M$714M$3M

CRIS vs DBVT vs IMVT vs AGENLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CRIS
DBVT
IMVT
AGEN
StockMay 20May 26Return
Curis, Inc. (CRIS)1003.5-96.5%
DBV Technologies S.… (DBVT)10041.2-58.8%
Immunovant, Inc. (IMVT)100106.1+6.1%
Agenus Inc. (AGEN)1005.0-95.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: CRIS vs DBVT vs IMVT vs AGEN

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: DBVT and AGEN are tied at the top with 2 categories each — the right choice depends on your priorities. Agenus Inc. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. IMVT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
CRIS
Curis, Inc.
The Secondary Option

CRIS lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
DBVT
DBV Technologies S.A.
The Income Pick

DBVT carries the broadest edge in this set and is the clearest fit for income & stability and defensive.

  • Dividend streak 0 yrs, beta 1.26
  • Beta 1.26, current ratio 3.67x
  • Beta 1.26 vs AGEN's 2.72
  • +110.4% vs CRIS's -72.0%
Best for: income & stability and defensive
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 173.6% 10Y total return vs DBVT's -87.0%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • 3.2% margin vs CRIS's -80.3%
Best for: long-term compounding and sleep-well-at-night
AGEN
Agenus Inc.
The Growth Play

AGEN is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
  • 10.4% revenue growth vs DBVT's -100.0%
  • 0.1% ROA vs DBVT's -89.0%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthAGEN logoAGEN10.4% revenue growth vs DBVT's -100.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs CRIS's -80.3%
Stability / SafetyDBVT logoDBVTBeta 1.26 vs AGEN's 2.72
DividendsTieNone of these 4 stocks pay a meaningful dividend
Momentum (1Y)DBVT logoDBVT+110.4% vs CRIS's -72.0%
Efficiency (ROA)AGEN logoAGEN0.1% ROA vs DBVT's -89.0%

CRIS vs DBVT vs IMVT vs AGEN — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CRISCuris, Inc.
FY 2025
Reportable Segment
100.0%$9M
DBVTDBV Technologies S.A.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

AGENAgenus Inc.
FY 2025
Non Cash Royalty Revenue
99.1%$109M
Other
0.9%$1M

CRIS vs DBVT vs IMVT vs AGEN — Financial Metrics

Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLAGENLAGGINGDBVT

Income & Cash Flow (Last 12 Months)

AGEN leads this category, winning 4 of 6 comparable metrics.

AGEN and IMVT operate at a comparable scale, with $114M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to CRIS's -80.3%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
RevenueTrailing 12 months$9M$0$0$114M
EBITDAEarnings before interest/tax-$33M-$112M-$487M-$10M
Net IncomeAfter-tax profit-$8M-$168M-$464M$115,000
Free Cash FlowCash after capex-$27M-$151M-$423M-$159M
Gross MarginGross profit ÷ Revenue+99.5%+35.7%
Operating MarginEBIT ÷ Revenue-3.5%-17.7%
Net MarginNet income ÷ Revenue-80.3%+0.1%
FCF MarginFCF ÷ Revenue-2.9%-139.1%
Rev. Growth (YoY)Latest quarter vs prior year-66.0%+27.5%
EPS Growth (YoY)Latest quarter vs prior year+198.4%+91.5%+19.7%+85.3%
AGEN leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

AGEN leads this category, winning 2 of 3 comparable metrics.
MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
Market CapShares × price$76M$1712.35T$5.5B$132M
Enterprise ValueMkt cap + debt − cash$73M$1712.35T$4.8B$140M
Trailing P/EPrice ÷ TTM EPS-0.99x-0.76x-9.97x-1102.94x
Forward P/EPrice ÷ next-FY EPS est.1.79x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue8.04x1.16x
Price / BookPrice ÷ Book value/share13.91x0.66x5.83x
Price / FCFMarket cap ÷ FCF
AGEN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

IMVT leads this category, winning 5 of 8 comparable metrics.

IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-139 for CRIS. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CRIS's 0.30x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs IMVT's 2/9, reflecting solid financial health.

MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
ROE (TTM)Return on equity-138.8%-130.2%-47.1%
ROA (TTM)Return on assets-26.1%-89.0%-44.1%+0.1%
ROICReturn on invested capital
ROCEReturn on capital employed-2.3%-145.7%-66.1%
Piotroski ScoreFundamental quality 0–93426
Debt / EquityFinancial leverage0.30x0.13x0.00x
Net DebtTotal debt minus cash-$3M-$172M-$714M$7M
Cash & Equiv.Liquid assets$5M$194M$714M$3M
Total DebtShort + long-term debt$2M$22M$98,000$10M
Interest CoverageEBIT ÷ Interest expense-107.35x-189.82x1.11x
IMVT leads this category, winning 5 of 8 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $28 for CRIS. Over the past 12 months, DBVT leads with a +110.4% total return vs CRIS's -72.0%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs CRIS's -67.0% — a key indicator of consistent wealth creation.

MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
YTD ReturnYear-to-date-41.1%+4.9%+5.1%+16.1%
1-Year ReturnPast 12 months-72.0%+110.4%+96.1%+27.1%
3-Year ReturnCumulative with dividends-96.4%+19.7%+40.9%-88.2%
5-Year ReturnCumulative with dividends-99.7%-69.1%+62.4%-93.9%
10-Year ReturnCumulative with dividends-99.7%-87.0%+173.6%-94.3%
CAGR (3Y)Annualised 3-year return-67.0%+6.2%+12.1%-51.0%
IMVT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

DBVT is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs CRIS's 18.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
Beta (5Y)Sensitivity to S&P 5001.87x1.26x1.37x2.72x
52-Week HighHighest price in past year$3.13$26.18$30.09$7.34
52-Week LowLowest price in past year$0.49$7.53$13.36$2.71
% of 52W HighCurrent price vs 52-week peak+18.4%+76.3%+90.5%+51.1%
RSI (14)Momentum oscillator 0–10048.948.160.248.8
Avg Volume (50D)Average daily shares traded444K252K1.4M814K
Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

AGEN leads this category, winning 1 of 1 comparable metric.

Analyst consensus: DBVT as "Buy", IMVT as "Buy", AGEN as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 67.2% for IMVT (target: $46).

MetricCRIS logoCRISCuris, Inc.DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$46.33$45.50$7.33
# AnalystsCovering analysts152311
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises01
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+0.1%
AGEN leads this category, winning 1 of 1 comparable metric.
Key Takeaway

AGEN leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 2 (Profitability & Efficiency, Total Returns). 1 tied.

Best OverallAgenus Inc. (AGEN)Leads 3 of 6 categories
Loading custom metrics...

CRIS vs DBVT vs IMVT vs AGEN: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CRIS or DBVT or IMVT or AGEN a better buy right now?

For growth investors, Agenus Inc.

(AGEN) is the stronger pick with 10. 4% revenue growth year-over-year, versus -13. 4% for Curis, Inc. (CRIS). Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CRIS or DBVT or IMVT or AGEN?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -99. 7% for Curis, Inc. (CRIS). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus CRIS's -99. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CRIS or DBVT or IMVT or AGEN?

By beta (market sensitivity over 5 years), DBV Technologies S.

A. (DBVT) is the lower-risk stock at 1. 26β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 116% more volatile than DBVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 30% for Curis, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CRIS or DBVT or IMVT or AGEN?

By revenue growth (latest reported year), Agenus Inc.

(AGEN) is pulling ahead at 10. 4% versus -13. 4% for Curis, Inc. (CRIS). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, AGEN leads at 5. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CRIS or DBVT or IMVT or AGEN?

Agenus Inc.

(AGEN) is the more profitable company, earning 0. 1% net margin versus -80. 3% for Curis, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -348. 4% for CRIS. At the gross margin level — before operating expenses — CRIS leads at 99. 5%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CRIS or DBVT or IMVT or AGEN more undervalued right now?

Analyst consensus price targets imply the most upside for DBVT: 131.

8% to $46. 33.

07

Which pays a better dividend — CRIS or DBVT or IMVT or AGEN?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is CRIS or DBVT or IMVT or AGEN better for a retirement portfolio?

For long-horizon retirement investors, Immunovant, Inc.

(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CRIS and DBVT and IMVT and AGEN?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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Stocks Like

CRIS

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 59%
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DBVT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
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IMVT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
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AGEN

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 13%
  • Gross Margin > 21%
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