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CTMX vs DBVT vs IMVT vs AGEN vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
CTMX
CytomX Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$681M
5Y Perf.-55.1%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1712.35T
5Y Perf.-59.3%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+12.8%
AGEN
Agenus Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$132M
5Y Perf.-94.9%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.50B
5Y Perf.-19.1%

CTMX vs DBVT vs IMVT vs AGEN vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
CTMX logoCTMX
DBVT logoDBVT
IMVT logoIMVT
AGEN logoAGEN
RCUS logoRCUS
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$681M$1712.35T$5.53B$132M$2.50B
Revenue (TTM)$36M$0.00$0.00$114M$236M
Net Income (TTM)$-59M$-168M$-464M$115K$-369M
Gross Margin69.7%35.7%90.7%
Operating Margin-181.9%-17.7%-168.6%
Forward P/E2.9x
Total Debt$4M$22M$98K$10M$99M
Cash & Equiv.$13M$194M$714M$3M$222M

CTMX vs DBVT vs IMVT vs AGEN vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

CTMX
DBVT
IMVT
AGEN
RCUS
StockMay 20May 26Return
CytomX Therapeutics… (CTMX)10044.9-55.1%
DBV Technologies S.… (DBVT)10040.7-59.3%
Immunovant, Inc. (IMVT)100112.8+12.8%
Agenus Inc. (AGEN)1005.1-94.9%
Arcus Biosciences, … (RCUS)10080.9-19.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: CTMX vs DBVT vs IMVT vs AGEN vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: CTMX and AGEN are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Agenus Inc. is the stronger pick specifically for growth and revenue expansion and operational efficiency and capital deployment. DBVT and IMVT also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
CTMX
CytomX Therapeutics, Inc.
The Income Pick

CTMX carries the broadest edge in this set and is the clearest fit for dividends and momentum.

  • 0.5% yield; the other 4 pay no meaningful dividend
  • +316.4% vs AGEN's +27.1%
Best for: dividends and momentum
DBVT
DBV Technologies S.A.
The Income Pick

DBVT ranks third and is worth considering specifically for income & stability.

  • Dividend streak 0 yrs, beta 1.26
  • Beta 1.26 vs AGEN's 2.72
Best for: income & stability
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 173.6% 10Y total return vs RCUS's 45.9%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
  • 3.2% margin vs CTMX's -166.4%
Best for: long-term compounding and sleep-well-at-night
AGEN
Agenus Inc.
The Growth Play

AGEN is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
  • 10.4% revenue growth vs DBVT's -100.0%
  • 0.1% ROA vs DBVT's -89.0%
Best for: growth exposure
RCUS
Arcus Biosciences, Inc.
The Healthcare Pick

Among these 5 stocks, RCUS doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthAGEN logoAGEN10.4% revenue growth vs DBVT's -100.0%
Quality / MarginsIMVT logoIMVT3.2% margin vs CTMX's -166.4%
Stability / SafetyDBVT logoDBVTBeta 1.26 vs AGEN's 2.72
DividendsCTMX logoCTMX0.5% yield; the other 4 pay no meaningful dividend
Momentum (1Y)CTMX logoCTMX+316.4% vs AGEN's +27.1%
Efficiency (ROA)AGEN logoAGEN0.1% ROA vs DBVT's -89.0%

CTMX vs DBVT vs IMVT vs AGEN vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

CTMXCytomX Therapeutics, Inc.

Segment breakdown not available.

DBVTDBV Technologies S.A.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

AGENAgenus Inc.
FY 2025
Non Cash Royalty Revenue
99.1%$109M
Other
0.9%$1M
RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

CTMX vs DBVT vs IMVT vs AGEN vs RCUS — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLAGENLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

AGEN leads this category, winning 4 of 6 comparable metrics.

RCUS and IMVT operate at a comparable scale, with $236M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to CTMX's -166.4%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$36M$0$0$114M$236M
EBITDAEarnings before interest/tax-$64M-$112M-$487M-$10M-$391M
Net IncomeAfter-tax profit-$59M-$168M-$464M$115,000-$369M
Free Cash FlowCash after capex-$80M-$151M-$423M-$159M-$489M
Gross MarginGross profit ÷ Revenue+69.7%+35.7%+90.7%
Operating MarginEBIT ÷ Revenue-181.9%-17.7%-168.6%
Net MarginNet income ÷ Revenue-166.4%+0.1%-156.4%
FCF MarginFCF ÷ Revenue-2.3%-139.1%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year-79.9%+27.5%-39.3%
EPS Growth (YoY)Latest quarter vs prior year-137.0%+91.5%+19.7%+85.3%+10.5%
AGEN leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

AGEN leads this category, winning 2 of 3 comparable metrics.
MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Market CapShares × price$681M$1712.35T$5.5B$132M$2.5B
Enterprise ValueMkt cap + debt − cash$673M$1712.35T$4.8B$140M$2.4B
Trailing P/EPrice ÷ TTM EPS-26.67x-0.76x-9.97x-1102.94x-7.54x
Forward P/EPrice ÷ next-FY EPS est.2.94x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue8.94x1.16x10.11x
Price / BookPrice ÷ Book value/share5.57x0.66x5.83x4.22x
Price / FCFMarket cap ÷ FCF
AGEN leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

Evenly matched — CTMX and IMVT and AGEN each lead in 3 of 9 comparable metrics.

CTMX delivers a -36.6% return on equity — every $100 of shareholder capital generates $-37 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to RCUS's 0.16x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs RCUS's 0/9, reflecting solid financial health.

MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-36.6%-130.2%-47.1%-69.0%
ROA (TTM)Return on assets-28.0%-89.0%-44.1%+0.1%-35.3%
ROICReturn on invested capital-47.7%-64.1%
ROCEReturn on capital employed-28.0%-145.7%-66.1%-42.1%
Piotroski ScoreFundamental quality 0–924260
Debt / EquityFinancial leverage0.04x0.13x0.00x0.16x
Net DebtTotal debt minus cash-$8M-$172M-$714M$7M-$123M
Cash & Equiv.Liquid assets$13M$194M$714M$3M$222M
Total DebtShort + long-term debt$4M$22M$98,000$10M$99M
Interest CoverageEBIT ÷ Interest expense-189.82x1.11x-13.38x
Evenly matched — CTMX and IMVT and AGEN each lead in 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

CTMX leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $611 for AGEN. Over the past 12 months, CTMX leads with a +316.4% total return vs AGEN's +27.1%. The 3-year compound annual growth rate (CAGR) favors CTMX at 33.5% vs AGEN's -51.0% — a key indicator of consistent wealth creation.

MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date-5.9%+4.9%+5.1%+16.1%+6.5%
1-Year ReturnPast 12 months+316.4%+110.4%+96.1%+27.1%+209.6%
3-Year ReturnCumulative with dividends+138.1%+19.7%+40.9%-88.2%+24.9%
5-Year ReturnCumulative with dividends-53.2%-69.1%+62.4%-93.9%-18.6%
10-Year ReturnCumulative with dividends-66.9%-87.0%+173.6%-94.3%+45.9%
CAGR (3Y)Annualised 3-year return+33.5%+6.2%+12.1%-51.0%+7.7%
CTMX leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

DBVT is the less volatile stock with a 1.26 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs CTMX's 48.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5001.47x1.26x1.36x2.58x1.84x
52-Week HighHighest price in past year$8.20$26.18$30.09$7.34$28.72
52-Week LowLowest price in past year$0.91$7.53$13.36$2.71$7.06
% of 52W HighCurrent price vs 52-week peak+48.8%+76.3%+90.5%+51.1%+86.3%
RSI (14)Momentum oscillator 0–10041.348.160.248.860.5
Avg Volume (50D)Average daily shares traded7.2M252K1.4M814K1.2M
Evenly matched — DBVT and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

AGEN leads this category, winning 1 of 1 comparable metric.

Analyst consensus: CTMX as "Buy", DBVT as "Buy", IMVT as "Buy", AGEN as "Buy", RCUS as "Buy". Consensus price targets imply 190.0% upside for CTMX (target: $12) vs 21.0% for RCUS (target: $30). CTMX is the only dividend payer here at 0.54% yield — a key consideration for income-focused portfolios.

MetricCTMX logoCTMXCytomX Therapeuti…DBVT logoDBVTDBV Technologies …IMVT logoIMVTImmunovant, Inc.AGEN logoAGENAgenus Inc.RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$11.60$46.33$45.50$7.33$30.00
# AnalystsCovering analysts2115231118
Dividend YieldAnnual dividend ÷ price+0.5%
Dividend StreakConsecutive years of raises001
Dividend / ShareAnnual DPS$0.02
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+0.1%0.0%
AGEN leads this category, winning 1 of 1 comparable metric.
Key Takeaway

AGEN leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). CTMX leads in 1 (Total Returns). 2 tied.

Best OverallAgenus Inc. (AGEN)Leads 3 of 6 categories
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CTMX vs DBVT vs IMVT vs AGEN vs RCUS: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is CTMX or DBVT or IMVT or AGEN or RCUS a better buy right now?

For growth investors, Agenus Inc.

(AGEN) is the stronger pick with 10. 4% revenue growth year-over-year, versus -44. 8% for CytomX Therapeutics, Inc. (CTMX). Analysts rate CytomX Therapeutics, Inc. (CTMX) a "Buy" — based on 21 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — CTMX or DBVT or IMVT or AGEN or RCUS?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -93. 9% for Agenus Inc. (AGEN). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus AGEN's -94. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — CTMX or DBVT or IMVT or AGEN or RCUS?

By beta (market sensitivity over 5 years), DBV Technologies S.

A. (DBVT) is the lower-risk stock at 1. 26β versus Agenus Inc. 's 2. 58β — meaning AGEN is approximately 105% more volatile than DBVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 16% for Arcus Biosciences, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — CTMX or DBVT or IMVT or AGEN or RCUS?

By revenue growth (latest reported year), Agenus Inc.

(AGEN) is pulling ahead at 10. 4% versus -44. 8% for CytomX Therapeutics, Inc. (CTMX). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — CTMX or DBVT or IMVT or AGEN or RCUS?

Agenus Inc.

(AGEN) is the more profitable company, earning 0. 1% net margin versus -142. 9% for Arcus Biosciences, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -156. 3% for RCUS. At the gross margin level — before operating expenses — CTMX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is CTMX or DBVT or IMVT or AGEN or RCUS more undervalued right now?

Analyst consensus price targets imply the most upside for CTMX: 190.

0% to $11. 60.

07

Which pays a better dividend — CTMX or DBVT or IMVT or AGEN or RCUS?

In this comparison, CTMX (0.

5% yield) pays a dividend. DBVT, IMVT, AGEN, RCUS do not pay a meaningful dividend and should not be held primarily for income.

08

Is CTMX or DBVT or IMVT or AGEN or RCUS better for a retirement portfolio?

For long-horizon retirement investors, CytomX Therapeutics, Inc.

(CTMX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (0. 5% yield). Agenus Inc. (AGEN) carries a higher beta of 2. 58 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CTMX: -67. 1%, AGEN: -94. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between CTMX and DBVT and IMVT and AGEN and RCUS?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

CTMX pays a dividend while DBVT, IMVT, AGEN, RCUS do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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