Biotechnology
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5 / 10Stock Comparison
GLMD vs LLY vs MRK vs ABBV vs GILD
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
GLMD vs LLY vs MRK vs ABBV vs GILD — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $1M | $921.16B | $277.34B | $358.42B | $166.40B |
| Revenue (TTM) | $0.00 | $72.25B | $64.93B | $61.16B | $29.73B |
| Net Income (TTM) | $-9M | $25.27B | $18.25B | $4.23B | $9.22B |
| Gross Margin | — | 83.5% | 74.2% | 70.2% | 63.0% |
| Operating Margin | — | 45.9% | 41.1% | 26.7% | 38.2% |
| Forward P/E | — | 26.3x | 21.9x | 14.3x | 15.4x |
| Total Debt | $0.00 | $42.50B | $50.53B | $69.07B | $24.59B |
| Cash & Equiv. | $5M | $7.16B | $14.56B | $5.23B | $7.56B |
GLMD vs LLY vs MRK vs ABBV vs GILD — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Galmed Pharmaceutic… (GLMD) | 100 | 0.1 | -99.9% |
| Eli Lilly and Compa… (LLY) | 100 | 620.1 | +520.1% |
| Merck & Co., Inc. (MRK) | 100 | 144.7 | +44.7% |
| AbbVie Inc. (ABBV) | 100 | 217.5 | +117.5% |
| Gilead Sciences, In… (GILD) | 100 | 168.7 | +68.7% |
Price return only. Dividends and distributions are not included.
Quick Verdict: GLMD vs LLY vs MRK vs ABBV vs GILD
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 5 stocks, GLMD doesn't own a clear edge in any measured category.
LLY carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 12.4% 10Y total return vs ABBV's 295.5%
- 44.7% revenue growth vs GLMD's -114.2%
- 35.0% margin vs GLMD's 2.6%
MRK ranks third and is worth considering specifically for sleep-well-at-night.
- Lower volatility, beta 0.48, Low D/E 96.0%, current ratio 1.54x
- +46.1% vs GLMD's -51.4%
ABBV is the #2 pick in this set and the best alternative if income & stability and defensive is your priority.
- Dividend streak 13 yrs, beta 0.34, yield 3.2%
- Beta 0.34, yield 3.2%, current ratio 0.67x
- Beta 0.34 vs GLMD's 1.79
- 3.2% yield, 13-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend)
GILD is the clearest fit if your priority is valuation efficiency.
- PEG 0.12 vs MRK's 1.03
- Lower P/E (15.4x vs 21.9x), PEG 0.12 vs 1.03
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs GLMD's -114.2% | |
| Value | Lower P/E (15.4x vs 21.9x), PEG 0.12 vs 1.03 | |
| Quality / Margins | 35.0% margin vs GLMD's 2.6% | |
| Stability / Safety | Beta 0.34 vs GLMD's 1.79 | |
| Dividends | 3.2% yield, 13-year raise streak, vs MRK's 2.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +46.1% vs GLMD's -51.4% | |
| Efficiency (ROA) | 22.7% ROA vs GLMD's -38.0%, ROIC 41.8% vs -41.4% |
GLMD vs LLY vs MRK vs ABBV vs GILD — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
GLMD vs LLY vs MRK vs ABBV vs GILD — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 3 of 6 categories
GLMD leads 0 • MRK leads 0 • ABBV leads 0 • GILD leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
LLY and GLMD operate at a comparable scale, with $72.2B and $0 in trailing revenue. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to ABBV's 6.9%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $72.2B | $64.9B | $61.2B | $29.7B |
| EBITDAEarnings before interest/tax | -$5M | $34.7B | $32.4B | $24.5B | $12.1B |
| Net IncomeAfter-tax profit | -$9M | $25.3B | $18.3B | $4.2B | $9.2B |
| Free Cash FlowCash after capex | -$5M | $13.6B | $12.4B | $18.7B | $10.3B |
| Gross MarginGross profit ÷ Revenue | — | +83.5% | +74.2% | +70.2% | +63.0% |
| Operating MarginEBIT ÷ Revenue | — | +45.9% | +41.1% | +26.7% | +38.2% |
| Net MarginNet income ÷ Revenue | — | +35.0% | +28.1% | +6.9% | +31.0% |
| FCF MarginFCF ÷ Revenue | — | +18.8% | +19.0% | +30.6% | +34.8% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | +55.5% | +4.5% | +10.0% | +4.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +70.4% | +169.9% | -19.6% | +57.4% | +54.8% |
Valuation Metrics
Evenly matched — GLMD and MRK and GILD each lead in 2 of 7 comparable metrics.
Valuation Metrics
At 15.4x trailing earnings, MRK trades at a 82% valuation discount to ABBV's 85.5x P/E. Adjusting for growth (PEG ratio), GILD offers better value at 0.15x vs LLY's 1.47x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1M | $921.2B | $277.3B | $358.4B | $166.4B |
| Enterprise ValueMkt cap + debt − cash | -$4M | $956.5B | $313.3B | $422.3B | $183.4B |
| Trailing P/EPrice ÷ TTM EPS | -0.08x | 42.48x | 15.42x | 85.50x | 19.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 26.30x | 21.93x | 14.28x | 15.37x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.47x | 0.73x | — | 0.15x |
| EV / EBITDAEnterprise value multiple | — | 30.60x | 10.68x | 14.96x | 16.95x |
| Price / SalesMarket cap ÷ Revenue | — | 14.13x | 4.27x | 5.86x | 5.65x |
| Price / BookPrice ÷ Book value/share | 0.04x | 32.99x | 5.35x | — | 7.44x |
| Price / FCFMarket cap ÷ FCF | — | 102.67x | 22.44x | 20.12x | 17.60x |
Profitability & Efficiency
LLY leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-42 for GLMD. MRK carries lower financial leverage with a 0.96x debt-to-equity ratio, signaling a more conservative balance sheet compared to LLY's 1.60x. On the Piotroski fundamental quality scale (0–9), GILD scores 9/9 vs GLMD's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -42.5% | +101.2% | +36.1% | +62.1% | +42.3% |
| ROA (TTM)Return on assets | -38.0% | +22.7% | +14.6% | +3.1% | +16.1% |
| ROICReturn on invested capital | -41.4% | +41.8% | +22.0% | +23.9% | +23.4% |
| ROCEReturn on capital employed | -41.6% | +46.6% | +23.8% | +21.5% | +25.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 8 | 4 | 6 | 9 |
| Debt / EquityFinancial leverage | — | 1.60x | 0.96x | — | 1.09x |
| Net DebtTotal debt minus cash | -$5M | $35.3B | $36.0B | $63.8B | $17.0B |
| Cash & Equiv.Liquid assets | $5M | $7.2B | $14.6B | $5.2B | $7.6B |
| Total DebtShort + long-term debt | $0 | $42.5B | $50.5B | $69.1B | $24.6B |
| Interest CoverageEBIT ÷ Interest expense | -19.18x | 35.68x | 19.68x | 3.28x | 8.87x |
Total Returns (Dividends Reinvested)
LLY leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $51,115 today (with dividends reinvested), compared to $13 for GLMD. Over the past 12 months, MRK leads with a +46.1% total return vs GLMD's -51.4%. The 3-year compound annual growth rate (CAGR) favors LLY at 31.8% vs GLMD's -78.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -23.9% | -9.6% | +6.3% | -10.1% | +10.9% |
| 1-Year ReturnPast 12 months | -51.4% | +26.3% | +46.1% | +11.3% | +38.8% |
| 3-Year ReturnCumulative with dividends | -99.0% | +129.1% | +2.9% | +50.4% | +82.4% |
| 5-Year ReturnCumulative with dividends | -99.9% | +411.1% | +70.2% | +101.3% | +124.2% |
| 10-Year ReturnCumulative with dividends | -99.9% | +1237.7% | +166.5% | +295.5% | +87.8% |
| CAGR (3Y)Annualised 3-year return | -78.7% | +31.8% | +0.9% | +14.6% | +22.2% |
Risk & Volatility
Evenly matched — MRK and ABBV each lead in 1 of 2 comparable metrics.
Risk & Volatility
ABBV is the less volatile stock with a 0.34 beta — it tends to amplify market swings less than GLMD's 1.79 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRK currently trades 89.7% from its 52-week high vs GLMD's 26.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.98x | 0.65x | 0.45x | 0.28x | 0.64x |
| 52-Week HighHighest price in past year | $2.34 | $1133.95 | $125.14 | $244.81 | $157.29 |
| 52-Week LowLowest price in past year | $0.41 | $623.78 | $73.31 | $176.57 | $95.30 |
| % of 52W HighCurrent price vs 52-week peak | +26.8% | +86.0% | +89.7% | +82.8% | +85.2% |
| RSI (14)Momentum oscillator 0–100 | 50.1 | 61.4 | 46.7 | 46.8 | 52.6 |
| Avg Volume (50D)Average daily shares traded | 3.7M | 2.6M | 7.3M | 5.8M | 5.8M |
Analyst Outlook
Evenly matched — MRK and ABBV each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: LLY as "Buy", MRK as "Buy", ABBV as "Buy", GILD as "Buy". Consensus price targets imply 29.3% upside for LLY (target: $1261) vs 15.2% for MRK (target: $129). For income investors, ABBV offers the higher dividend yield at 3.24% vs LLY's 0.61%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $1261.11 | $129.31 | $256.64 | $162.00 |
| # AnalystsCovering analysts | — | 45 | 37 | 41 | 58 |
| Dividend YieldAnnual dividend ÷ price | — | +0.6% | +2.9% | +3.2% | +2.4% |
| Dividend StreakConsecutive years of raises | — | 11 | 14 | 13 | 11 |
| Dividend / ShareAnnual DPS | — | $6.00 | $3.26 | $6.57 | $3.19 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | +1.8% | +0.3% | +1.2% |
LLY leads in 3 of 6 categories — strongest in Income & Cash Flow and Profitability & Efficiency. 3 categories are tied.
GLMD vs LLY vs MRK vs ABBV vs GILD: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is GLMD or LLY or MRK or ABBV or GILD a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — GLMD or LLY or MRK or ABBV or GILD?
On trailing P/E, Merck & Co.
, Inc. (MRK) is the cheapest at 15. 4x versus AbbVie Inc. at 85. 5x. On forward P/E, AbbVie Inc. is actually cheaper at 14. 3x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Gilead Sciences, Inc. wins at 0. 12x versus Merck & Co. , Inc. 's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — GLMD or LLY or MRK or ABBV or GILD?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +411.
1%, compared to -99. 9% for Galmed Pharmaceuticals Ltd. (GLMD). Over 10 years, the gap is even starker: LLY returned +1203% versus GLMD's -99. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — GLMD or LLY or MRK or ABBV or GILD?
By beta (market sensitivity over 5 years), AbbVie Inc.
(ABBV) is the lower-risk stock at 0. 28β versus Galmed Pharmaceuticals Ltd. 's 1. 98β — meaning GLMD is approximately 618% more volatile than ABBV relative to the S&P 500. On balance sheet safety, Merck & Co. , Inc. (MRK) carries a lower debt/equity ratio of 96% versus 160% for Eli Lilly and Company — giving it more financial flexibility in a downturn.
05Which is growing faster — GLMD or LLY or MRK or ABBV or GILD?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: Gilead Sciences, Inc. grew EPS 1684% year-over-year, compared to -0. 8% for AbbVie Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — GLMD or LLY or MRK or ABBV or GILD?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus 0. 0% for Galmed Pharmaceuticals Ltd. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 0. 0% for GLMD. At the gross margin level — before operating expenses — GILD leads at 86. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is GLMD or LLY or MRK or ABBV or GILD more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Gilead Sciences, Inc. (GILD) is the more undervalued stock at a PEG of 0. 12x versus Merck & Co. , Inc. 's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, AbbVie Inc. (ABBV) trades at 14. 3x forward P/E versus 26. 3x for Eli Lilly and Company — 12. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LLY: 29. 3% to $1261. 11.
08Which pays a better dividend — GLMD or LLY or MRK or ABBV or GILD?
In this comparison, ABBV (3.
2% yield), MRK (2. 9% yield), GILD (2. 4% yield), LLY (0. 6% yield) pay a dividend. GLMD does not pay a meaningful dividend and should not be held primarily for income.
09Is GLMD or LLY or MRK or ABBV or GILD better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
65), 0. 6% yield, +1203% 10Y return). Galmed Pharmaceuticals Ltd. (GLMD) carries a higher beta of 1. 98 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (LLY: +1203%, GLMD: -99. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between GLMD and LLY and MRK and ABBV and GILD?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: GLMD is a small-cap quality compounder stock; LLY is a large-cap high-growth stock; MRK is a large-cap deep-value stock; ABBV is a large-cap income-oriented stock; GILD is a mid-cap quality compounder stock. LLY, MRK, ABBV, GILD pay a dividend while GLMD does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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