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IBO vs NNVC vs SIGA vs GILD vs NVAX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
IBO
Impact BioMedical Inc.

Biotechnology

HealthcareAMEX • US
Market Cap$144M
5Y Perf.-99.8%
NNVC
NanoViricides, Inc.

Biotechnology

HealthcareAMEX • US
Market Cap$31M
5Y Perf.+35.2%
SIGA
SIGA Technologies, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$339M
5Y Perf.-15.7%
GILD
Gilead Sciences, Inc.

Drug Manufacturers - General

HealthcareNASDAQ • US
Market Cap$166.40B
5Y Perf.+74.2%
NVAX
Novavax, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.50B
5Y Perf.+14.7%

IBO vs NNVC vs SIGA vs GILD vs NVAX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
IBO logoIBO
NNVC logoNNVC
SIGA logoSIGA
GILD logoGILD
NVAX logoNVAX
IndustryBiotechnologyBiotechnologyDrug Manufacturers - Specialty & GenericDrug Manufacturers - GeneralBiotechnology
Market Cap$144M$31M$339M$166.40B$1.50B
Revenue (TTM)$0.00$0.00$94M$29.73B$596M
Net Income (TTM)$-25M$-2.22T$-4.04T$9.22B$-88M
Gross Margin100.0%61.8%63.0%84.6%
Operating Margin23.7%27.7%38.2%-11.2%
Forward P/E2.8x15.7x3.6x
Total Debt$9M$0.00$595K$24.59B$249M
Cash & Equiv.$2M$2M$155M$7.56B$241M

IBO vs NNVC vs SIGA vs GILD vs NVAXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

IBO
NNVC
SIGA
GILD
NVAX
StockMay 23May 26Return
Impact BioMedical I… (IBO)1000.2-99.8%
NanoViricides, Inc. (NNVC)100135.2+35.2%
SIGA Technologies, … (SIGA)10084.3-15.7%
Gilead Sciences, In… (GILD)100174.2+74.2%
Novavax, Inc. (NVAX)100114.7+14.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: IBO vs NNVC vs SIGA vs GILD vs NVAX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: SIGA and GILD are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. Gilead Sciences, Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. NVAX and IBO also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
IBO
Impact BioMedical Inc.
The Defensive Choice

IBO is the clearest fit if your priority is stability.

  • Beta 0.12 vs NVAX's 2.11
Best for: stability
NNVC
NanoViricides, Inc.
The Healthcare Pick

Among these 5 stocks, NNVC doesn't own a clear edge in any measured category.

Best for: healthcare exposure
SIGA
SIGA Technologies, Inc.
The Income Pick

SIGA has the current edge in this matchup, primarily because of its strength in income & stability and long-term compounding.

  • Dividend streak 4 yrs, beta 1.15, yield 12.7%
  • 7.6% 10Y total return vs GILD's 87.8%
  • Lower volatility, beta 1.15, Low D/E 0.3%, current ratio 11.83x
  • Beta 1.15, yield 12.7%, current ratio 11.83x
Best for: income & stability and long-term compounding
GILD
Gilead Sciences, Inc.
The Quality Compounder

GILD is the #2 pick in this set and the best alternative if quality and efficiency is your priority.

  • 31.0% margin vs SIGA's -43K%
  • 16.1% ROA vs IBO's -124.8%, ROIC 23.4% vs 1.5%
Best for: quality and efficiency
NVAX
Novavax, Inc.
The Growth Play

NVAX ranks third and is worth considering specifically for growth exposure.

  • Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
  • 64.7% revenue growth vs NNVC's -258K%
  • +55.1% vs SIGA's +1.5%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthNVAX logoNVAX64.7% revenue growth vs NNVC's -258K%
ValueSIGA logoSIGALower P/E (2.8x vs 3.6x)
Quality / MarginsGILD logoGILD31.0% margin vs SIGA's -43K%
Stability / SafetyIBO logoIBOBeta 0.12 vs NVAX's 2.11
DividendsSIGA logoSIGA12.7% yield, 4-year raise streak, vs GILD's 2.4%, (3 stocks pay no dividend)
Momentum (1Y)NVAX logoNVAX+55.1% vs SIGA's +1.5%
Efficiency (ROA)GILD logoGILD16.1% ROA vs IBO's -124.8%, ROIC 23.4% vs 1.5%

IBO vs NNVC vs SIGA vs GILD vs NVAX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

IBOImpact BioMedical Inc.

Segment breakdown not available.

NNVCNanoViricides, Inc.

Segment breakdown not available.

SIGASIGA Technologies, Inc.
FY 2025
Product Sales and Supportive Services
93.1%$88M
Research and Development
6.9%$7M
GILDGilead Sciences, Inc.
FY 2025
Products, Other HIV
79.7%$20.8B
Cell Therapy Products, Total Cell Therapy Product Sales
8.4%$2.2B
Trodelvy
5.4%$1.4B
Veklury
3.5%$911M
Other Products, Total Other product sales
3.1%$799M
NVAXNovavax, Inc.
FY 2025
Product
50.0%$685M
Nuvaxovid Sales
45.6%$625M
Supply Sales
4.4%$60M

IBO vs NNVC vs SIGA vs GILD vs NVAX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLGILDLAGGINGNVAX

Income & Cash Flow (Last 12 Months)

GILD leads this category, winning 4 of 6 comparable metrics.

GILD and NNVC operate at a comparable scale, with $29.7B and $0 in trailing revenue. GILD is the more profitable business, keeping 31.0% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, GILD holds the edge at +4.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
RevenueTrailing 12 months$0$0$94M$29.7B$596M
EBITDAEarnings before interest/tax-$28M-$8M$26M$12.1B-$47M
Net IncomeAfter-tax profit-$25M-$2.22T-$4.04T$9.2B-$88M
Free Cash FlowCash after capex-$3M-$3.73T$33M$10.3B-$96M
Gross MarginGross profit ÷ Revenue+100.0%+61.8%+63.0%+84.6%
Operating MarginEBIT ÷ Revenue+23.7%+27.7%+38.2%-11.2%
Net MarginNet income ÷ Revenue-88.0%-43117.4%+31.0%-14.7%
FCF MarginFCF ÷ Revenue-168.1%+35.2%+34.8%-16.1%
Rev. Growth (YoY)Latest quarter vs prior year-11.3%+4.4%-79.1%
EPS Growth (YoY)Latest quarter vs prior year-19.5%+21.4%+54.8%-102.0%
GILD leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

SIGA leads this category, winning 3 of 6 comparable metrics.

At 3.6x trailing earnings, NVAX trades at a 82% valuation discount to GILD's 19.8x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than IBO's 226.5x.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
Market CapShares × price$144M$31M$339M$166.4B$1.5B
Enterprise ValueMkt cap + debt − cash$149M$29M$185M$183.4B$1.5B
Trailing P/EPrice ÷ TTM EPS-84.24x-2.25x14.33x19.77x3.63x
Forward P/EPrice ÷ next-FY EPS est.2.78x15.69x
PEG RatioP/E ÷ EPS growth rate0.15x
EV / EBITDAEnterprise value multiple226.49x7.60x16.95x2.56x
Price / SalesMarket cap ÷ Revenue84.02x3.58x5.65x1.34x
Price / BookPrice ÷ Book value/share27.06x2.86x1.70x7.44x
Price / FCFMarket cap ÷ FCF6.96x17.60x
SIGA leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

GILD leads this category, winning 4 of 9 comparable metrics.

GILD delivers a 42.3% return on equity — every $100 of shareholder capital generates $42 in annual profit, vs $-4 for IBO. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IBO's 1.23x. On the Piotroski fundamental quality scale (0–9), GILD scores 9/9 vs NNVC's 1/9, reflecting strong financial health.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
ROE (TTM)Return on equity-3.7%-20.1%-10.7%+42.3%
ROA (TTM)Return on assets-124.8%-18.1%-7.4%+16.1%-7.4%
ROICReturn on invested capital+1.5%-114.0%+33.7%+23.4%
ROCEReturn on capital employed+2.6%-101.1%+11.3%+25.1%+100.4%
Piotroski ScoreFundamental quality 0–941595
Debt / EquityFinancial leverage1.23x0.00x1.09x
Net DebtTotal debt minus cash$7M-$2M-$154M$17.0B$8M
Cash & Equiv.Liquid assets$2M$2M$155M$7.6B$241M
Total DebtShort + long-term debt$9M$0$595,169$24.6B$249M
Interest CoverageEBIT ÷ Interest expense-21.60x8.87x-5.10x
GILD leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GILD leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in GILD five years ago would be worth $22,418 today (with dividends reinvested), compared to $16 for IBO. Over the past 12 months, NVAX leads with a +55.1% total return vs SIGA's +1.5%. The 3-year compound annual growth rate (CAGR) favors GILD at 22.2% vs IBO's -88.3% — a key indicator of consistent wealth creation.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
YTD ReturnYear-to-date+19.0%+17.4%-15.0%+10.9%+29.5%
1-Year ReturnPast 12 months+21.0%+14.5%+1.5%+38.8%+55.1%
3-Year ReturnCumulative with dividends-99.8%+10.9%+22.2%+82.4%+23.9%
5-Year ReturnCumulative with dividends-99.8%-60.9%+1.4%+124.2%-94.8%
10-Year ReturnCumulative with dividends-97.5%-95.5%+764.0%+87.8%-90.4%
CAGR (3Y)Annualised 3-year return-88.3%+3.5%+6.9%+22.2%+7.4%
GILD leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — IBO and GILD each lead in 1 of 2 comparable metrics.

IBO is the less volatile stock with a 0.12 beta — it tends to amplify market swings less than NVAX's 2.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GILD currently trades 85.2% from its 52-week high vs IBO's 31.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
Beta (5Y)Sensitivity to S&P 5000.12x1.34x1.15x0.66x2.11x
52-Week HighHighest price in past year$1.95$2.23$9.62$157.29$11.97
52-Week LowLowest price in past year$0.36$0.85$4.29$95.30$5.80
% of 52W HighCurrent price vs 52-week peak+31.7%+63.7%+49.2%+85.2%+77.1%
RSI (14)Momentum oscillator 0–10049.567.047.052.664.4
Avg Volume (50D)Average daily shares traded4.5M249K688K5.8M4.4M
Evenly matched — IBO and GILD each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — SIGA and GILD each lead in 1 of 2 comparable metrics.

Analyst consensus: SIGA as "Buy", GILD as "Buy", NVAX as "Buy". Consensus price targets imply 95.0% upside for NVAX (target: $18) vs 20.8% for GILD (target: $162). For income investors, SIGA offers the higher dividend yield at 12.73% vs GILD's 2.38%.

MetricIBO logoIBOImpact BioMedical…NNVC logoNNVCNanoViricides, In…SIGA logoSIGASIGA Technologies…GILD logoGILDGilead Sciences, …NVAX logoNVAXNovavax, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$161.88$18.00
# AnalystsCovering analysts15823
Dividend YieldAnnual dividend ÷ price+12.7%+2.4%
Dividend StreakConsecutive years of raises124111
Dividend / ShareAnnual DPS$0.60$3.19
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+1.2%+0.3%
Evenly matched — SIGA and GILD each lead in 1 of 2 comparable metrics.
Key Takeaway

GILD leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). SIGA leads in 1 (Valuation Metrics). 2 tied.

Best OverallGilead Sciences, Inc. (GILD)Leads 3 of 6 categories
Loading custom metrics...

IBO vs NNVC vs SIGA vs GILD vs NVAX: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is IBO or NNVC or SIGA or GILD or NVAX a better buy right now?

For growth investors, Novavax, Inc.

(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus -31. 8% for SIGA Technologies, Inc. (SIGA). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate SIGA Technologies, Inc. (SIGA) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — IBO or NNVC or SIGA or GILD or NVAX?

On trailing P/E, Novavax, Inc.

(NVAX) is the cheapest at 3. 6x versus Gilead Sciences, Inc. at 19. 8x. On forward P/E, SIGA Technologies, Inc. is actually cheaper at 2. 8x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — IBO or NNVC or SIGA or GILD or NVAX?

Over the past 5 years, Gilead Sciences, Inc.

(GILD) delivered a total return of +124. 2%, compared to -99. 8% for Impact BioMedical Inc. (IBO). Over 10 years, the gap is even starker: SIGA returned +764. 0% versus IBO's -97. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — IBO or NNVC or SIGA or GILD or NVAX?

By beta (market sensitivity over 5 years), Impact BioMedical Inc.

(IBO) is the lower-risk stock at 0. 12β versus Novavax, Inc. 's 2. 11β — meaning NVAX is approximately 1587% more volatile than IBO relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 123% for Impact BioMedical Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — IBO or NNVC or SIGA or GILD or NVAX?

By revenue growth (latest reported year), Novavax, Inc.

(NVAX) is pulling ahead at 64. 7% versus -31. 8% for SIGA Technologies, Inc. (SIGA). On earnings-per-share growth, the picture is similar: Gilead Sciences, Inc. grew EPS 1684% year-over-year, compared to -60. 2% for SIGA Technologies, Inc.. Over a 3-year CAGR, IBO leads at 259. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — IBO or NNVC or SIGA or GILD or NVAX?

Novavax, Inc.

(NVAX) is the more profitable company, earning 39. 2% net margin versus -88. 0% for Impact BioMedical Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus 0. 0% for NNVC. At the gross margin level — before operating expenses — IBO leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is IBO or NNVC or SIGA or GILD or NVAX more undervalued right now?

On forward earnings alone, SIGA Technologies, Inc.

(SIGA) trades at 2. 8x forward P/E versus 15. 7x for Gilead Sciences, Inc. — 12. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVAX: 95. 0% to $18. 00.

08

Which pays a better dividend — IBO or NNVC or SIGA or GILD or NVAX?

In this comparison, SIGA (12.

7% yield), GILD (2. 4% yield) pay a dividend. IBO, NNVC, NVAX do not pay a meaningful dividend and should not be held primarily for income.

09

Is IBO or NNVC or SIGA or GILD or NVAX better for a retirement portfolio?

For long-horizon retirement investors, SIGA Technologies, Inc.

(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), 12. 7% yield, +764. 0% 10Y return). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +764. 0%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between IBO and NNVC and SIGA and GILD and NVAX?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: IBO is a small-cap quality compounder stock; NNVC is a small-cap quality compounder stock; SIGA is a small-cap deep-value stock; GILD is a mid-cap quality compounder stock; NVAX is a small-cap high-growth stock. SIGA, GILD pay a dividend while IBO, NNVC, NVAX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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  • Market Cap > $100B
  • Gross Margin > 60%
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  • Gross Margin > 37%
  • Dividend Yield > 5.0%
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