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Stock Comparison

LTRN vs CASI vs IMVT vs CRL vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LTRN
Lantern Pharma Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$23M
5Y Perf.-83.5%
CASI
CASI Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-99.1%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.88B
5Y Perf.+18.9%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$8.76B
5Y Perf.+1.9%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.33B
5Y Perf.+26.0%

LTRN vs CASI vs IMVT vs CRL vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LTRN logoLTRN
CASI logoCASI
IMVT logoIMVT
CRL logoCRL
IQV logoIQV
IndustryBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & ResearchMedical - Diagnostics & Research
Market Cap$23M$2M$5.88B$8.76B$30.33B
Revenue (TTM)$0.00$27M$0.00$4.03B$16.63B
Net Income (TTM)$-19M$-49M$-464M$-185M$1.39B
Gross Margin35.8%31.9%26.1%
Operating Margin-168.0%11.8%13.9%
Forward P/E16.0x14.0x
Total Debt$244K$22M$98K$3.07B$16.17B
Cash & Equiv.$8M$13M$714M$214M$1.98B

LTRN vs CASI vs IMVT vs CRL vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LTRN
CASI
IMVT
CRL
IQV
StockJun 20May 26Return
Lantern Pharma Inc. (LTRN)10016.5-83.5%
CASI Pharmaceutical… (CASI)1000.9-99.1%
Immunovant, Inc. (IMVT)100118.9+18.9%
Charles River Labor… (CRL)100101.9+1.9%
IQVIA Holdings Inc. (IQV)100126.0+26.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: LTRN vs CASI vs IMVT vs CRL vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IQV leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. CASI Pharmaceuticals, Inc. is the stronger pick specifically for dividend income and shareholder returns. IMVT also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
LTRN
Lantern Pharma Inc.
The Healthcare Pick

LTRN lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
CASI
CASI Pharmaceuticals, Inc.
The Income Pick

CASI is the #2 pick in this set and the best alternative if dividends is your priority.

  • 31.1% yield; the other 4 pay no meaningful dividend
Best for: dividends
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.

  • 190.9% 10Y total return vs IQV's 166.6%
  • Lower volatility, beta 1.36, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.36, current ratio 11.16x
  • +102.4% vs CASI's -92.2%
Best for: long-term compounding and sleep-well-at-night
CRL
Charles River Laboratories International, Inc.
The Healthcare Pick

Among these 5 stocks, CRL doesn't own a clear edge in any measured category.

Best for: healthcare exposure
IQV
IQVIA Holdings Inc.
The Income Pick

IQV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 2 yrs, beta 1.32
  • Rev growth 5.9%, EPS growth 4.7%, 3Y rev CAGR 4.2%
  • 5.9% revenue growth vs IMVT's -21.3%
  • Lower P/E (14.0x vs 16.0x)
Best for: income & stability and growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthIQV logoIQV5.9% revenue growth vs IMVT's -21.3%
ValueIQV logoIQVLower P/E (14.0x vs 16.0x)
Quality / MarginsIQV logoIQV8.3% margin vs CASI's -183.9%
Stability / SafetyIQV logoIQVBeta 1.32 vs LTRN's 2.49
DividendsCASI logoCASI31.1% yield; the other 4 pay no meaningful dividend
Momentum (1Y)IMVT logoIMVT+102.4% vs CASI's -92.2%
Efficiency (ROA)IQV logoIQV4.7% ROA vs CASI's -131.5%, ROIC 8.7% vs -153.0%

LTRN vs CASI vs IMVT vs CRL vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LTRNLantern Pharma Inc.

Segment breakdown not available.

CASICASI Pharmaceuticals, Inc.
FY 2019
E V O M E L A
100.0%$4M
IMVTImmunovant, Inc.

Segment breakdown not available.

CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

LTRN vs CASI vs IMVT vs CRL vs IQV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLIQVLAGGINGCRL

Income & Cash Flow (Last 12 Months)

IQV leads this category, winning 4 of 6 comparable metrics.

IQV and IMVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. IQV is the more profitable business, keeping 8.3% of every revenue dollar as net income compared to CASI's -183.9%. On growth, IQV holds the edge at +8.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$0$27M$0$4.0B$16.6B
EBITDAEarnings before interest/tax-$20M-$44M-$487M$824M$3.5B
Net IncomeAfter-tax profit-$19M-$49M-$464M-$185M$1.4B
Free Cash FlowCash after capex-$17M$0-$423M$391M$2.7B
Gross MarginGross profit ÷ Revenue+35.8%+31.9%+26.1%
Operating MarginEBIT ÷ Revenue-168.0%+11.8%+13.9%
Net MarginNet income ÷ Revenue-183.9%-4.6%+8.3%
FCF MarginFCF ÷ Revenue-103.2%+9.7%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year-60.5%+1.2%+8.4%
EPS Growth (YoY)Latest quarter vs prior year+7.1%-23.6%+19.7%-160.0%+15.0%
IQV leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — CRL and IQV each lead in 2 of 6 comparable metrics.

On an enterprise value basis, CRL's 12.7x EV/EBITDA is more attractive than IQV's 13.0x.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Market CapShares × price$23M$2M$5.9B$8.8B$30.3B
Enterprise ValueMkt cap + debt − cash$16M$11M$5.2B$11.6B$44.5B
Trailing P/EPrice ÷ TTM EPS-0.00x-0.06x-10.60x-61.04x22.79x
Forward P/EPrice ÷ next-FY EPS est.16.00x13.96x
PEG RatioP/E ÷ EPS growth rate0.56x
EV / EBITDAEnterprise value multiple12.75x12.98x
Price / SalesMarket cap ÷ Revenue0.08x2.18x1.86x
Price / BookPrice ÷ Book value/share1.07x1.25x6.20x2.74x4.68x
Price / FCFMarket cap ÷ FCF16.90x14.79x
Evenly matched — CRL and IQV each lead in 2 of 6 comparable metrics.

Profitability & Efficiency

IQV leads this category, winning 5 of 9 comparable metrics.

IQV delivers a 22.1% return on equity — every $100 of shareholder capital generates $22 in annual profit, vs $-3 for CASI. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CASI's 11.96x. On the Piotroski fundamental quality scale (0–9), CRL scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity-126.0%-3.0%-47.1%-5.7%+22.1%
ROA (TTM)Return on assets-97.4%-131.5%-44.1%-2.5%+4.7%
ROICReturn on invested capital-100.6%-153.0%+6.3%+8.7%
ROCEReturn on capital employed-71.4%-104.6%-66.1%+8.1%+11.0%
Piotroski ScoreFundamental quality 0–922244
Debt / EquityFinancial leverage0.01x11.96x0.00x0.95x2.44x
Net DebtTotal debt minus cash-$7M$9M-$714M$2.9B$14.2B
Cash & Equiv.Liquid assets$8M$13M$714M$214M$2.0B
Total DebtShort + long-term debt$243,657$22M$98,000$3.1B$16.2B
Interest CoverageEBIT ÷ Interest expense-66.88x4.29x3.10x
IQV leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $18,445 today (with dividends reinvested), compared to $104 for CASI. Over the past 12 months, IMVT leads with a +102.4% total return vs CASI's -92.2%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.4% vs CASI's -60.8% — a key indicator of consistent wealth creation.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date-32.5%-81.6%+11.7%-12.3%-20.7%
1-Year ReturnPast 12 months-45.6%-92.2%+102.4%+25.7%+16.6%
3-Year ReturnCumulative with dividends-60.4%-94.0%+49.8%-6.5%-5.9%
5-Year ReturnCumulative with dividends-86.1%-99.0%+84.4%-46.6%-22.8%
10-Year ReturnCumulative with dividends-86.0%-99.0%+190.9%+114.0%+166.6%
CAGR (3Y)Annualised 3-year return-26.6%-60.8%+14.4%-2.2%-2.0%
IMVT leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — CASI and IMVT each lead in 1 of 2 comparable metrics.

CASI is the less volatile stock with a -0.22 beta — it tends to amplify market swings less than LTRN's 2.49 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs CASI's 4.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5002.49x-0.22x1.36x1.44x1.32x
52-Week HighHighest price in past year$5.74$3.09$30.09$228.88$247.05
52-Week LowLowest price in past year$1.11$0.05$13.36$132.58$134.65
% of 52W HighCurrent price vs 52-week peak+36.6%+4.9%+96.2%+77.6%+72.3%
RSI (14)Momentum oscillator 0–10044.224.250.657.460.3
Avg Volume (50D)Average daily shares traded693K55K1.4M792K1.5M
Evenly matched — CASI and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

IQV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: IMVT as "Buy", CRL as "Buy", IQV as "Buy". Consensus price targets imply 57.2% upside for IMVT (target: $46) vs 16.2% for CRL (target: $206). CASI is the only dividend payer here at 31.10% yield — a key consideration for income-focused portfolios.

MetricLTRN logoLTRNLantern Pharma In…CASI logoCASICASI Pharmaceutic…IMVT logoIMVTImmunovant, Inc.CRL logoCRLCharles River Lab…IQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$45.50$206.43$223.75
# AnalystsCovering analysts233644
Dividend YieldAnnual dividend ÷ price+31.1%
Dividend StreakConsecutive years of raises012
Dividend / ShareAnnual DPS$0.05
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+4.1%+4.1%
IQV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

IQV leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IMVT leads in 1 (Total Returns). 2 tied.

Best OverallIQVIA Holdings Inc. (IQV)Leads 3 of 6 categories
Loading custom metrics...

LTRN vs CASI vs IMVT vs CRL vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is LTRN or CASI or IMVT or CRL or IQV a better buy right now?

For growth investors, IQVIA Holdings Inc.

(IQV) is the stronger pick with 5. 9% revenue growth year-over-year, versus -15. 8% for CASI Pharmaceuticals, Inc. (CASI). IQVIA Holdings Inc. (IQV) offers the better valuation at 22. 8x trailing P/E (14. 0x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — LTRN or CASI or IMVT or CRL or IQV?

On forward P/E, IQVIA Holdings Inc.

is actually cheaper at 14. 0x.

03

Which is the better long-term investment — LTRN or CASI or IMVT or CRL or IQV?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +84. 4%, compared to -99. 0% for CASI Pharmaceuticals, Inc. (CASI). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus CASI's -99. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — LTRN or CASI or IMVT or CRL or IQV?

By beta (market sensitivity over 5 years), CASI Pharmaceuticals, Inc.

(CASI) is the lower-risk stock at -0. 22β versus Lantern Pharma Inc. 's 2. 49β — meaning LTRN is approximately -1220% more volatile than CASI relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 12% for CASI Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — LTRN or CASI or IMVT or CRL or IQV?

By revenue growth (latest reported year), IQVIA Holdings Inc.

(IQV) is pulling ahead at 5. 9% versus -15. 8% for CASI Pharmaceuticals, Inc. (CASI). On earnings-per-share growth, the picture is similar: IQVIA Holdings Inc. grew EPS 4. 7% year-over-year, compared to -1312. 6% for Lantern Pharma Inc.. Over a 3-year CAGR, IQV leads at 4. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — LTRN or CASI or IMVT or CRL or IQV?

IQVIA Holdings Inc.

(IQV) is the more profitable company, earning 8. 3% net margin versus -137. 6% for CASI Pharmaceuticals, Inc. — meaning it keeps 8. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IQV leads at 14. 0% versus -138. 8% for CASI. At the gross margin level — before operating expenses — CASI leads at 39. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is LTRN or CASI or IMVT or CRL or IQV more undervalued right now?

On forward earnings alone, IQVIA Holdings Inc.

(IQV) trades at 14. 0x forward P/E versus 16. 0x for Charles River Laboratories International, Inc. — 2. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IMVT: 57. 2% to $45. 50.

08

Which pays a better dividend — LTRN or CASI or IMVT or CRL or IQV?

In this comparison, CASI (31.

1% yield) pays a dividend. LTRN, IMVT, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.

09

Is LTRN or CASI or IMVT or CRL or IQV better for a retirement portfolio?

For long-horizon retirement investors, CASI Pharmaceuticals, Inc.

(CASI) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 22), 31. 1% yield). Lantern Pharma Inc. (LTRN) carries a higher beta of 2. 49 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CASI: -99. 0%, LTRN: -86. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between LTRN and CASI and IMVT and CRL and IQV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: LTRN is a small-cap quality compounder stock; CASI is a small-cap income-oriented stock; IMVT is a small-cap quality compounder stock; CRL is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. CASI pays a dividend while LTRN, IMVT, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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LTRN

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  • Sector: Healthcare
  • Market Cap > $100B
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CASI

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 21%
  • Dividend Yield > 12.4%
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IMVT

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CRL

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  • Market Cap > $100B
  • Gross Margin > 19%
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IQV

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  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 5%
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