Biotechnology
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5 / 10Stock Comparison
LTRN vs CASI vs IMVT vs CRL vs IQV
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Diagnostics & Research
Medical - Diagnostics & Research
LTRN vs CASI vs IMVT vs CRL vs IQV — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Medical - Diagnostics & Research | Medical - Diagnostics & Research |
| Market Cap | $23M | $2M | $5.88B | $8.76B | $30.33B |
| Revenue (TTM) | $0.00 | $27M | $0.00 | $4.03B | $16.63B |
| Net Income (TTM) | $-19M | $-49M | $-464M | $-185M | $1.39B |
| Gross Margin | — | 35.8% | — | 31.9% | 26.1% |
| Operating Margin | — | -168.0% | — | 11.8% | 13.9% |
| Forward P/E | — | — | — | 16.0x | 14.0x |
| Total Debt | $244K | $22M | $98K | $3.07B | $16.17B |
| Cash & Equiv. | $8M | $13M | $714M | $214M | $1.98B |
LTRN vs CASI vs IMVT vs CRL vs IQV — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | May 26 | Return |
|---|---|---|---|
| Lantern Pharma Inc. (LTRN) | 100 | 16.5 | -83.5% |
| CASI Pharmaceutical… (CASI) | 100 | 0.9 | -99.1% |
| Immunovant, Inc. (IMVT) | 100 | 118.9 | +18.9% |
| Charles River Labor… (CRL) | 100 | 101.9 | +1.9% |
| IQVIA Holdings Inc. (IQV) | 100 | 126.0 | +26.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: LTRN vs CASI vs IMVT vs CRL vs IQV
Each card shows where this stock fits in a portfolio — not just who wins on paper.
LTRN lags the leaders in this set but could rank higher in a more targeted comparison.
CASI is the #2 pick in this set and the best alternative if dividends is your priority.
- 31.1% yield; the other 4 pay no meaningful dividend
IMVT ranks third and is worth considering specifically for long-term compounding and sleep-well-at-night.
- 190.9% 10Y total return vs IQV's 166.6%
- Lower volatility, beta 1.36, Low D/E 0.0%, current ratio 11.16x
- Beta 1.36, current ratio 11.16x
- +102.4% vs CASI's -92.2%
Among these 5 stocks, CRL doesn't own a clear edge in any measured category.
IQV carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 2 yrs, beta 1.32
- Rev growth 5.9%, EPS growth 4.7%, 3Y rev CAGR 4.2%
- 5.9% revenue growth vs IMVT's -21.3%
- Lower P/E (14.0x vs 16.0x)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 5.9% revenue growth vs IMVT's -21.3% | |
| Value | Lower P/E (14.0x vs 16.0x) | |
| Quality / Margins | 8.3% margin vs CASI's -183.9% | |
| Stability / Safety | Beta 1.32 vs LTRN's 2.49 | |
| Dividends | 31.1% yield; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +102.4% vs CASI's -92.2% | |
| Efficiency (ROA) | 4.7% ROA vs CASI's -131.5%, ROIC 8.7% vs -153.0% |
LTRN vs CASI vs IMVT vs CRL vs IQV — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
LTRN vs CASI vs IMVT vs CRL vs IQV — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
IQV leads in 3 of 6 categories
IMVT leads 1 • LTRN leads 0 • CASI leads 0 • CRL leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
IQV leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IQV and IMVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. IQV is the more profitable business, keeping 8.3% of every revenue dollar as net income compared to CASI's -183.9%. On growth, IQV holds the edge at +8.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $27M | $0 | $4.0B | $16.6B |
| EBITDAEarnings before interest/tax | -$20M | -$44M | -$487M | $824M | $3.5B |
| Net IncomeAfter-tax profit | -$19M | -$49M | -$464M | -$185M | $1.4B |
| Free Cash FlowCash after capex | -$17M | $0 | -$423M | $391M | $2.7B |
| Gross MarginGross profit ÷ Revenue | — | +35.8% | — | +31.9% | +26.1% |
| Operating MarginEBIT ÷ Revenue | — | -168.0% | — | +11.8% | +13.9% |
| Net MarginNet income ÷ Revenue | — | -183.9% | — | -4.6% | +8.3% |
| FCF MarginFCF ÷ Revenue | — | -103.2% | — | +9.7% | +16.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -60.5% | — | +1.2% | +8.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +7.1% | -23.6% | +19.7% | -160.0% | +15.0% |
Valuation Metrics
Evenly matched — CRL and IQV each lead in 2 of 6 comparable metrics.
Valuation Metrics
On an enterprise value basis, CRL's 12.7x EV/EBITDA is more attractive than IQV's 13.0x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $23M | $2M | $5.9B | $8.8B | $30.3B |
| Enterprise ValueMkt cap + debt − cash | $16M | $11M | $5.2B | $11.6B | $44.5B |
| Trailing P/EPrice ÷ TTM EPS | -0.00x | -0.06x | -10.60x | -61.04x | 22.79x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 16.00x | 13.96x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 0.56x |
| EV / EBITDAEnterprise value multiple | — | — | — | 12.75x | 12.98x |
| Price / SalesMarket cap ÷ Revenue | — | 0.08x | — | 2.18x | 1.86x |
| Price / BookPrice ÷ Book value/share | 1.07x | 1.25x | 6.20x | 2.74x | 4.68x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 16.90x | 14.79x |
Profitability & Efficiency
IQV leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
IQV delivers a 22.1% return on equity — every $100 of shareholder capital generates $22 in annual profit, vs $-3 for CASI. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CASI's 11.96x. On the Piotroski fundamental quality scale (0–9), CRL scores 4/9 vs IMVT's 2/9, reflecting mixed financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -126.0% | -3.0% | -47.1% | -5.7% | +22.1% |
| ROA (TTM)Return on assets | -97.4% | -131.5% | -44.1% | -2.5% | +4.7% |
| ROICReturn on invested capital | -100.6% | -153.0% | — | +6.3% | +8.7% |
| ROCEReturn on capital employed | -71.4% | -104.6% | -66.1% | +8.1% | +11.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 | 2 | 4 | 4 |
| Debt / EquityFinancial leverage | 0.01x | 11.96x | 0.00x | 0.95x | 2.44x |
| Net DebtTotal debt minus cash | -$7M | $9M | -$714M | $2.9B | $14.2B |
| Cash & Equiv.Liquid assets | $8M | $13M | $714M | $214M | $2.0B |
| Total DebtShort + long-term debt | $243,657 | $22M | $98,000 | $3.1B | $16.2B |
| Interest CoverageEBIT ÷ Interest expense | — | -66.88x | — | 4.29x | 3.10x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $18,445 today (with dividends reinvested), compared to $104 for CASI. Over the past 12 months, IMVT leads with a +102.4% total return vs CASI's -92.2%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.4% vs CASI's -60.8% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -32.5% | -81.6% | +11.7% | -12.3% | -20.7% |
| 1-Year ReturnPast 12 months | -45.6% | -92.2% | +102.4% | +25.7% | +16.6% |
| 3-Year ReturnCumulative with dividends | -60.4% | -94.0% | +49.8% | -6.5% | -5.9% |
| 5-Year ReturnCumulative with dividends | -86.1% | -99.0% | +84.4% | -46.6% | -22.8% |
| 10-Year ReturnCumulative with dividends | -86.0% | -99.0% | +190.9% | +114.0% | +166.6% |
| CAGR (3Y)Annualised 3-year return | -26.6% | -60.8% | +14.4% | -2.2% | -2.0% |
Risk & Volatility
Evenly matched — CASI and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
CASI is the less volatile stock with a -0.22 beta — it tends to amplify market swings less than LTRN's 2.49 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 96.2% from its 52-week high vs CASI's 4.9% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.49x | -0.22x | 1.36x | 1.44x | 1.32x |
| 52-Week HighHighest price in past year | $5.74 | $3.09 | $30.09 | $228.88 | $247.05 |
| 52-Week LowLowest price in past year | $1.11 | $0.05 | $13.36 | $132.58 | $134.65 |
| % of 52W HighCurrent price vs 52-week peak | +36.6% | +4.9% | +96.2% | +77.6% | +72.3% |
| RSI (14)Momentum oscillator 0–100 | 44.2 | 24.2 | 50.6 | 57.4 | 60.3 |
| Avg Volume (50D)Average daily shares traded | 693K | 55K | 1.4M | 792K | 1.5M |
Analyst Outlook
IQV leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: IMVT as "Buy", CRL as "Buy", IQV as "Buy". Consensus price targets imply 57.2% upside for IMVT (target: $46) vs 16.2% for CRL (target: $206). CASI is the only dividend payer here at 31.10% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | — | $45.50 | $206.43 | $223.75 |
| # AnalystsCovering analysts | — | — | 23 | 36 | 44 |
| Dividend YieldAnnual dividend ÷ price | — | +31.1% | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 | 2 |
| Dividend / ShareAnnual DPS | — | $0.05 | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +4.1% | +4.1% |
IQV leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IMVT leads in 1 (Total Returns). 2 tied.
LTRN vs CASI vs IMVT vs CRL vs IQV: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is LTRN or CASI or IMVT or CRL or IQV a better buy right now?
For growth investors, IQVIA Holdings Inc.
(IQV) is the stronger pick with 5. 9% revenue growth year-over-year, versus -15. 8% for CASI Pharmaceuticals, Inc. (CASI). IQVIA Holdings Inc. (IQV) offers the better valuation at 22. 8x trailing P/E (14. 0x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — LTRN or CASI or IMVT or CRL or IQV?
On forward P/E, IQVIA Holdings Inc.
is actually cheaper at 14. 0x.
03Which is the better long-term investment — LTRN or CASI or IMVT or CRL or IQV?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +84. 4%, compared to -99. 0% for CASI Pharmaceuticals, Inc. (CASI). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus CASI's -99. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — LTRN or CASI or IMVT or CRL or IQV?
By beta (market sensitivity over 5 years), CASI Pharmaceuticals, Inc.
(CASI) is the lower-risk stock at -0. 22β versus Lantern Pharma Inc. 's 2. 49β — meaning LTRN is approximately -1220% more volatile than CASI relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 12% for CASI Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — LTRN or CASI or IMVT or CRL or IQV?
By revenue growth (latest reported year), IQVIA Holdings Inc.
(IQV) is pulling ahead at 5. 9% versus -15. 8% for CASI Pharmaceuticals, Inc. (CASI). On earnings-per-share growth, the picture is similar: IQVIA Holdings Inc. grew EPS 4. 7% year-over-year, compared to -1312. 6% for Lantern Pharma Inc.. Over a 3-year CAGR, IQV leads at 4. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — LTRN or CASI or IMVT or CRL or IQV?
IQVIA Holdings Inc.
(IQV) is the more profitable company, earning 8. 3% net margin versus -137. 6% for CASI Pharmaceuticals, Inc. — meaning it keeps 8. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: IQV leads at 14. 0% versus -138. 8% for CASI. At the gross margin level — before operating expenses — CASI leads at 39. 1%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is LTRN or CASI or IMVT or CRL or IQV more undervalued right now?
On forward earnings alone, IQVIA Holdings Inc.
(IQV) trades at 14. 0x forward P/E versus 16. 0x for Charles River Laboratories International, Inc. — 2. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IMVT: 57. 2% to $45. 50.
08Which pays a better dividend — LTRN or CASI or IMVT or CRL or IQV?
In this comparison, CASI (31.
1% yield) pays a dividend. LTRN, IMVT, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.
09Is LTRN or CASI or IMVT or CRL or IQV better for a retirement portfolio?
For long-horizon retirement investors, CASI Pharmaceuticals, Inc.
(CASI) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 22), 31. 1% yield). Lantern Pharma Inc. (LTRN) carries a higher beta of 2. 49 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CASI: -99. 0%, LTRN: -86. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between LTRN and CASI and IMVT and CRL and IQV?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: LTRN is a small-cap quality compounder stock; CASI is a small-cap income-oriented stock; IMVT is a small-cap quality compounder stock; CRL is a small-cap quality compounder stock; IQV is a mid-cap quality compounder stock. CASI pays a dividend while LTRN, IMVT, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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