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LTRN vs ONCO vs CASI vs ALDX vs IMVT

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
LTRN
Lantern Pharma Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$23M
5Y Perf.-65.9%
ONCO
Onconetix, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1M
5Y Perf.-100.0%
CASI
CASI Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-97.3%
ALDX
Aldeyra Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$104M
5Y Perf.-57.2%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+418.6%

LTRN vs ONCO vs CASI vs ALDX vs IMVT — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
LTRN logoLTRN
ONCO logoONCO
CASI logoCASI
ALDX logoALDX
IMVT logoIMVT
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyBiotechnology
Market Cap$23M$1M$2M$104M$5.53B
Revenue (TTM)$0.00$815K$27M$0.00$0.00
Net Income (TTM)$-19M$-14M$-49M$-43M$-464M
Gross Margin77.6%35.8%
Operating Margin-21.9%-168.0%
Forward P/E24.7x
Total Debt$244K$49K$22M$15M$98K
Cash & Equiv.$8M$5M$13M$55M$714M

LTRN vs ONCO vs CASI vs ALDX vs IMVTLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

LTRN
ONCO
CASI
ALDX
IMVT
StockFeb 22May 26Return
Lantern Pharma Inc. (LTRN)10034.1-65.9%
Onconetix, Inc. (ONCO)1000.0-100.0%
CASI Pharmaceutical… (CASI)1002.7-97.3%
Aldeyra Therapeutic… (ALDX)10042.8-57.2%
Immunovant, Inc. (IMVT)100518.6+418.6%

Price return only. Dividends and distributions are not included.

Quick Verdict: LTRN vs ONCO vs CASI vs ALDX vs IMVT

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: IMVT leads in 3 of 6 categories (5-stock set), making it the strongest pick for capital preservation and lower volatility and recent price momentum and sentiment. Aldeyra Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and profitability and margin quality. CASI also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
LTRN
Lantern Pharma Inc.
The Healthcare Pick

LTRN lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ONCO
Onconetix, Inc.
The Income Pick

ONCO is the clearest fit if your priority is income & stability.

  • Dividend streak 0 yrs, beta 1.41, yield 30.9%
Best for: income & stability
CASI
CASI Pharmaceuticals, Inc.
The Growth Play

CASI ranks third and is worth considering specifically for growth exposure.

  • Rev growth -15.8%, EPS growth -26.7%, 3Y rev CAGR -1.8%
  • 31.1% yield, vs ONCO's 30.9%, (3 stocks pay no dividend)
Best for: growth exposure
ALDX
Aldeyra Therapeutics, Inc.
The Growth Leader

ALDX is the #2 pick in this set and the best alternative if growth and quality is your priority.

  • 3.6% revenue growth vs ONCO's -67.7%
  • 4.1% margin vs ONCO's -17.2%
Best for: growth and quality
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT carries the broadest edge in this set and is the clearest fit for long-term compounding and sleep-well-at-night.

  • 173.6% 10Y total return vs ALDX's -72.1%
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
  • Beta 1.37 vs LTRN's 2.42, lower leverage
Best for: long-term compounding and sleep-well-at-night
See the full category breakdown
CategoryWinnerWhy
GrowthALDX logoALDX3.6% revenue growth vs ONCO's -67.7%
Quality / MarginsALDX logoALDX4.1% margin vs ONCO's -17.2%
Stability / SafetyIMVT logoIMVTBeta 1.37 vs LTRN's 2.42, lower leverage
DividendsCASI logoCASI31.1% yield, vs ONCO's 30.9%, (3 stocks pay no dividend)
Momentum (1Y)IMVT logoIMVT+96.1% vs ONCO's -98.6%
Efficiency (ROA)IMVT logoIMVT-44.1% ROA vs CASI's -131.5%

LTRN vs ONCO vs CASI vs ALDX vs IMVT — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

LTRNLantern Pharma Inc.

Segment breakdown not available.

ONCOOnconetix, Inc.
FY 2025
License
0.0%$0
CASICASI Pharmaceuticals, Inc.
FY 2019
E V O M E L A
100.0%$4M
ALDXAldeyra Therapeutics, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

LTRN vs ONCO vs CASI vs ALDX vs IMVT — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCASILAGGINGALDX

Income & Cash Flow (Last 12 Months)

Evenly matched — ONCO and CASI each lead in 3 of 6 comparable metrics.

CASI and IMVT operate at a comparable scale, with $27M and $0 in trailing revenue. Profitability is closely matched — net margins range from -183.9% (CASI) to -17.2% (ONCO). On growth, ONCO holds the edge at -57.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
RevenueTrailing 12 months$0$815,371$27M$0$0
EBITDAEarnings before interest/tax-$20M-$18M-$44M-$45M-$487M
Net IncomeAfter-tax profit-$19M-$14M-$49M-$43M-$464M
Free Cash FlowCash after capex-$17M-$10M$0-$40M-$423M
Gross MarginGross profit ÷ Revenue+77.6%+35.8%
Operating MarginEBIT ÷ Revenue-21.9%-168.0%
Net MarginNet income ÷ Revenue-17.2%-183.9%
FCF MarginFCF ÷ Revenue-11.9%-103.2%
Rev. Growth (YoY)Latest quarter vs prior year-57.4%-60.5%
EPS Growth (YoY)Latest quarter vs prior year+7.1%+120.9%-23.6%+48.0%+19.7%
Evenly matched — ONCO and CASI each lead in 3 of 6 comparable metrics.

Valuation Metrics

Evenly matched — ONCO and CASI and IMVT each lead in 1 of 3 comparable metrics.
MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
Market CapShares × price$23M$1M$2M$104M$5.5B
Enterprise ValueMkt cap + debt − cash$15M-$4M$11M$65M$4.8B
Trailing P/EPrice ÷ TTM EPS-0.00x-0.09x-0.06x-1.84x-9.97x
Forward P/EPrice ÷ next-FY EPS est.24.71x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple
Price / SalesMarket cap ÷ Revenue1.70x0.08x
Price / BookPrice ÷ Book value/share1.04x0.08x1.25x1.45x5.83x
Price / FCFMarket cap ÷ FCF
Evenly matched — ONCO and CASI and IMVT each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

Evenly matched — ONCO and IMVT each lead in 4 of 9 comparable metrics.

IMVT delivers a -47.1% return on equity — every $100 of shareholder capital generates $-47 in annual profit, vs $-3 for CASI. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CASI's 11.96x. On the Piotroski fundamental quality scale (0–9), ONCO scores 5/9 vs ALDX's 1/9, reflecting solid financial health.

MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
ROE (TTM)Return on equity-126.0%-189.8%-3.0%-87.7%-47.1%
ROA (TTM)Return on assets-97.4%-68.0%-131.5%-55.5%-44.1%
ROICReturn on invested capital-100.6%-32.8%-153.0%-3.7%
ROCEReturn on capital employed-71.4%-49.4%-104.6%-56.7%-66.1%
Piotroski ScoreFundamental quality 0–925212
Debt / EquityFinancial leverage0.01x0.00x11.96x0.22x0.00x
Net DebtTotal debt minus cash-$7M-$5M$9M-$39M-$714M
Cash & Equiv.Liquid assets$8M$5M$13M$55M$714M
Total DebtShort + long-term debt$243,657$48,774$22M$15M$98,000
Interest CoverageEBIT ÷ Interest expense-26.95x-66.88x-21.72x
Evenly matched — ONCO and IMVT each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $0 for ONCO. Over the past 12 months, IMVT leads with a +96.1% total return vs ONCO's -98.6%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs ONCO's -97.2% — a key indicator of consistent wealth creation.

MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
YTD ReturnYear-to-date-34.4%-95.0%-81.6%-63.0%+5.1%
1-Year ReturnPast 12 months-53.0%-98.6%-91.2%-13.9%+96.1%
3-Year ReturnCumulative with dividends-61.5%-100.0%-94.0%-83.8%+40.9%
5-Year ReturnCumulative with dividends-86.9%-100.0%-99.1%-86.1%+62.4%
10-Year ReturnCumulative with dividends-86.4%-100.0%-99.0%-72.1%+173.6%
CAGR (3Y)Annualised 3-year return-27.3%-97.2%-60.8%-45.5%+12.1%
IMVT leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

Evenly matched — CASI and IMVT each lead in 1 of 2 comparable metrics.

CASI is the less volatile stock with a -0.12 beta — it tends to amplify market swings less than LTRN's 2.42 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs ONCO's 0.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
Beta (5Y)Sensitivity to S&P 5002.49x1.28x-0.22x1.28x1.36x
52-Week HighHighest price in past year$5.74$74.30$3.09$6.18$30.09
52-Week LowLowest price in past year$1.11$0.37$0.05$1.07$13.36
% of 52W HighCurrent price vs 52-week peak+35.5%+0.5%+4.9%+28.0%+90.5%
RSI (14)Momentum oscillator 0–10047.028.824.242.960.2
Avg Volume (50D)Average daily shares traded694K9.4M146K3.6M1.4M
Evenly matched — CASI and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

CASI leads this category, winning 1 of 1 comparable metric.

Analyst consensus: ALDX as "Buy", IMVT as "Buy". Consensus price targets imply 459.0% upside for ALDX (target: $10) vs 67.2% for IMVT (target: $46). For income investors, CASI offers the higher dividend yield at 31.10% vs ONCO's 30.89%.

MetricLTRN logoLTRNLantern Pharma In…ONCO logoONCOOnconetix, Inc.CASI logoCASICASI Pharmaceutic…ALDX logoALDXAldeyra Therapeut…IMVT logoIMVTImmunovant, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$9.67$45.50
# AnalystsCovering analysts1923
Dividend YieldAnnual dividend ÷ price+30.9%+31.1%
Dividend StreakConsecutive years of raises00
Dividend / ShareAnnual DPS$0.12$0.05
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%0.0%
CASI leads this category, winning 1 of 1 comparable metric.
Key Takeaway

IMVT leads in 1 of 6 categories (Total Returns). CASI leads in 1 (Analyst Outlook). 4 tied.

Best OverallCASI Pharmaceuticals, Inc. (CASI)Leads 1 of 6 categories
Loading custom metrics...

LTRN vs ONCO vs CASI vs ALDX vs IMVT: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is LTRN or ONCO or CASI or ALDX or IMVT a better buy right now?

For growth investors, CASI Pharmaceuticals, Inc.

(CASI) is the stronger pick with -15. 8% revenue growth year-over-year, versus -67. 7% for Onconetix, Inc. (ONCO). Analysts rate Aldeyra Therapeutics, Inc. (ALDX) a "Buy" — based on 19 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — LTRN or ONCO or CASI or ALDX or IMVT?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +62. 4%, compared to -100. 0% for Onconetix, Inc. (ONCO). Over 10 years, the gap is even starker: IMVT returned +190. 9% versus ONCO's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — LTRN or ONCO or CASI or ALDX or IMVT?

By beta (market sensitivity over 5 years), CASI Pharmaceuticals, Inc.

(CASI) is the lower-risk stock at -0. 22β versus Lantern Pharma Inc. 's 2. 49β — meaning LTRN is approximately -1220% more volatile than CASI relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 12% for CASI Pharmaceuticals, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — LTRN or ONCO or CASI or ALDX or IMVT?

By revenue growth (latest reported year), CASI Pharmaceuticals, Inc.

(CASI) is pulling ahead at -15. 8% versus -67. 7% for Onconetix, Inc. (ONCO). On earnings-per-share growth, the picture is similar: Onconetix, Inc. grew EPS 99. 1% year-over-year, compared to -1312. 6% for Lantern Pharma Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — LTRN or ONCO or CASI or ALDX or IMVT?

Lantern Pharma Inc.

(LTRN) is the more profitable company, earning 0. 0% net margin versus -1721. 0% for Onconetix, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LTRN leads at 0. 0% versus -778. 2% for ONCO. At the gross margin level — before operating expenses — ONCO leads at 77. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is LTRN or ONCO or CASI or ALDX or IMVT more undervalued right now?

Analyst consensus price targets imply the most upside for ALDX: 459.

0% to $9. 67.

07

Which pays a better dividend — LTRN or ONCO or CASI or ALDX or IMVT?

In this comparison, CASI (31.

1% yield), ONCO (30. 9% yield) pay a dividend. LTRN, ALDX, IMVT do not pay a meaningful dividend and should not be held primarily for income.

08

Is LTRN or ONCO or CASI or ALDX or IMVT better for a retirement portfolio?

For long-horizon retirement investors, CASI Pharmaceuticals, Inc.

(CASI) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0. 22), 31. 1% yield). Lantern Pharma Inc. (LTRN) carries a higher beta of 2. 49 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (CASI: -99. 0%, LTRN: -86. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between LTRN and ONCO and CASI and ALDX and IMVT?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: LTRN is a small-cap quality compounder stock; ONCO is a small-cap income-oriented stock; CASI is a small-cap income-oriented stock; ALDX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock. ONCO, CASI pay a dividend while LTRN, ALDX, IMVT do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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LTRN

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  • Gross Margin > 46%
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