Biotechnology
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5 / 10Stock Comparison
MRUS vs LLY vs MRK vs ABBV vs JNJ
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
Drug Manufacturers - General
MRUS vs LLY vs MRK vs ABBV vs JNJ — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General | Drug Manufacturers - General |
| Market Cap | $6.83B | $896.11B | $275.10B | $356.49B | $533.36B |
| Revenue (TTM) | $51M | $72.25B | $64.93B | $61.16B | $92.15B |
| Net Income (TTM) | $-335M | $25.27B | $18.25B | $4.23B | $25.12B |
| Gross Margin | -217.5% | 83.5% | 74.2% | 70.2% | 68.1% |
| Operating Margin | -6.5% | 45.9% | 41.1% | 26.7% | 26.1% |
| Forward P/E | — | 26.3x | 21.7x | 14.2x | 19.1x |
| Total Debt | $10M | $42.50B | $50.53B | $69.07B | $36.63B |
| Cash & Equiv. | $293M | $7.16B | $14.56B | $5.23B | $24.11B |
MRUS vs LLY vs MRK vs ABBV vs JNJ — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | Jan 26 | Return |
|---|---|---|---|
| Merus N.V. (MRUS) | 100 | 659.3 | +559.3% |
| Eli Lilly and Compa… (LLY) | 100 | 702.6 | +602.6% |
| Merck & Co., Inc. (MRK) | 100 | 136.8 | +36.8% |
| AbbVie Inc. (ABBV) | 100 | 246.6 | +146.6% |
| Johnson & Johnson (JNJ) | 100 | 139.1 | +39.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MRUS vs LLY vs MRK vs ABBV vs JNJ
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MRUS ranks third and is worth considering specifically for sleep-well-at-night.
- Lower volatility, beta 0.21, Low D/E 1.5%, current ratio 6.54x
- +110.4% vs ABBV's +12.2%
LLY carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
- 12.0% 10Y total return vs MRUS's 8.0%
- PEG 0.91 vs JNJ's 34.02
- 44.7% revenue growth vs MRUS's -12.4%
Among these 5 stocks, MRK doesn't own a clear edge in any measured category.
ABBV is the #2 pick in this set and the best alternative if value and dividends is your priority.
- Lower P/E (14.2x vs 19.1x)
- 3.3% yield, 13-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend)
JNJ is the clearest fit if your priority is income & stability and defensive.
- Dividend streak 36 yrs, beta 0.04, yield 2.2%
- Beta 0.04, yield 2.2%, current ratio 1.11x
- Beta 0.04 vs LLY's 0.65, lower leverage
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 44.7% revenue growth vs MRUS's -12.4% | |
| Value | Lower P/E (14.2x vs 19.1x) | |
| Quality / Margins | 35.0% margin vs MRUS's -6.5% | |
| Stability / Safety | Beta 0.04 vs LLY's 0.65, lower leverage | |
| Dividends | 3.3% yield, 13-year raise streak, vs JNJ's 2.2%, (1 stock pays no dividend) | |
| Momentum (1Y) | +110.4% vs ABBV's +12.2% | |
| Efficiency (ROA) | 22.7% ROA vs MRUS's -43.4%, ROIC 41.8% vs -74.6% |
MRUS vs LLY vs MRK vs ABBV vs JNJ — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
MRUS vs LLY vs MRK vs ABBV vs JNJ — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
LLY leads in 2 of 6 categories
MRK leads 1 • MRUS leads 1 • ABBV leads 0 • JNJ leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
LLY leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JNJ is the larger business by revenue, generating $92.1B annually — 1800.7x MRUS's $51M. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to MRUS's -6.5%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $51M | $72.2B | $64.9B | $61.2B | $92.1B |
| EBITDAEarnings before interest/tax | -$329M | $34.7B | $32.4B | $24.5B | $31.4B |
| Net IncomeAfter-tax profit | -$335M | $25.3B | $18.3B | $4.2B | $25.1B |
| Free Cash FlowCash after capex | -$318M | $13.6B | $12.4B | $18.7B | $19.1B |
| Gross MarginGross profit ÷ Revenue | -2.2% | +83.5% | +74.2% | +70.2% | +68.1% |
| Operating MarginEBIT ÷ Revenue | -6.5% | +45.9% | +41.1% | +26.7% | +26.1% |
| Net MarginNet income ÷ Revenue | -6.5% | +35.0% | +28.1% | +6.9% | +27.3% |
| FCF MarginFCF ÷ Revenue | -6.2% | +18.8% | +19.0% | +30.6% | +20.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | -1.9% | +55.5% | +4.5% | +10.0% | +6.8% |
| EPS Growth (YoY)Latest quarter vs prior year | +13.7% | +169.9% | -19.6% | +57.4% | +91.0% |
Valuation Metrics
MRK leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 15.3x trailing earnings, MRK trades at a 82% valuation discount to ABBV's 85.0x P/E. Adjusting for growth (PEG ratio), MRK offers better value at 0.72x vs JNJ's 34.02x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $6.8B | $896.1B | $275.1B | $356.5B | $533.4B |
| Enterprise ValueMkt cap + debt − cash | $6.5B | $931.5B | $311.1B | $420.3B | $545.9B |
| Trailing P/EPrice ÷ TTM EPS | -26.87x | 41.33x | 15.30x | 85.04x | 38.22x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 26.30x | 21.69x | 14.17x | 19.12x |
| PEG RatioP/E ÷ EPS growth rate | — | 1.43x | 0.72x | — | 34.02x |
| EV / EBITDAEnterprise value multiple | — | 29.80x | 10.61x | 14.89x | 18.51x |
| Price / SalesMarket cap ÷ Revenue | 195.71x | 13.75x | 4.24x | 5.83x | 6.00x |
| Price / BookPrice ÷ Book value/share | 8.92x | 32.10x | 5.30x | — | 7.52x |
| Price / FCFMarket cap ÷ FCF | — | 99.88x | 22.26x | 20.01x | 26.88x |
Profitability & Efficiency
LLY leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-51 for MRUS. MRUS carries lower financial leverage with a 0.02x debt-to-equity ratio, signaling a more conservative balance sheet compared to LLY's 1.60x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs MRK's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -50.6% | +101.2% | +36.1% | +62.1% | +31.7% |
| ROA (TTM)Return on assets | -43.4% | +22.7% | +14.6% | +3.1% | +13.0% |
| ROICReturn on invested capital | -74.6% | +41.8% | +22.0% | +23.9% | +20.7% |
| ROCEReturn on capital employed | -48.4% | +46.6% | +23.8% | +21.5% | +17.6% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 8 | 4 | 6 | 5 |
| Debt / EquityFinancial leverage | 0.02x | 1.60x | 0.96x | — | 0.51x |
| Net DebtTotal debt minus cash | -$283M | $35.3B | $36.0B | $63.8B | $12.5B |
| Cash & Equiv.Liquid assets | $293M | $7.2B | $14.6B | $5.2B | $24.1B |
| Total DebtShort + long-term debt | $10M | $42.5B | $50.5B | $69.1B | $36.6B |
| Interest CoverageEBIT ÷ Interest expense | — | 35.68x | 19.68x | 3.28x | 48.23x |
Total Returns (Dividends Reinvested)
MRUS leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in LLY five years ago would be worth $49,927 today (with dividends reinvested), compared to $14,389 for JNJ. Over the past 12 months, MRUS leads with a +110.4% total return vs ABBV's +12.2%. The 3-year compound annual growth rate (CAGR) favors MRUS at 65.1% vs MRK's 0.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | 0.0% | -12.0% | +5.4% | -10.6% | +7.4% |
| 1-Year ReturnPast 12 months | +110.4% | +27.0% | +47.7% | +12.2% | +45.5% |
| 3-Year ReturnCumulative with dividends | +350.2% | +123.0% | +2.1% | +49.7% | +45.5% |
| 5-Year ReturnCumulative with dividends | +330.2% | +399.3% | +69.5% | +99.6% | +43.9% |
| 10-Year ReturnCumulative with dividends | +796.4% | +1202.6% | +164.7% | +293.8% | +131.3% |
| CAGR (3Y)Annualised 3-year return | +65.1% | +30.6% | +0.7% | +14.4% | +13.3% |
Risk & Volatility
Evenly matched — MRUS and JNJ each lead in 1 of 2 comparable metrics.
Risk & Volatility
JNJ is the less volatile stock with a 0.04 beta — it tends to amplify market swings less than LLY's 0.65 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRUS currently trades 92.6% from its 52-week high vs ABBV's 82.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.21x | 0.65x | 0.45x | 0.28x | 0.04x |
| 52-Week HighHighest price in past year | $97.14 | $1133.95 | $125.14 | $244.81 | $251.71 |
| 52-Week LowLowest price in past year | $39.40 | $623.78 | $73.31 | $176.57 | $146.12 |
| % of 52W HighCurrent price vs 52-week peak | +92.6% | +83.6% | +89.0% | +82.3% | +87.9% |
| RSI (14)Momentum oscillator 0–100 | 14.9 | 58.4 | 43.7 | 43.9 | 34.3 |
| Avg Volume (50D)Average daily shares traded | 0 | 2.6M | 7.2M | 5.8M | 6.9M |
Analyst Outlook
Evenly matched — ABBV and JNJ each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: MRUS as "Hold", LLY as "Buy", MRK as "Buy", ABBV as "Buy", JNJ as "Buy". Consensus price targets imply 33.0% upside for LLY (target: $1261) vs -1.5% for MRUS (target: $89). For income investors, ABBV offers the higher dividend yield at 3.26% vs LLY's 0.63%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $88.69 | $1261.11 | $129.31 | $256.69 | $249.27 |
| # AnalystsCovering analysts | 22 | 45 | 37 | 41 | 40 |
| Dividend YieldAnnual dividend ÷ price | — | +0.6% | +2.9% | +3.3% | +2.2% |
| Dividend StreakConsecutive years of raises | — | 11 | 14 | 13 | 36 |
| Dividend / ShareAnnual DPS | — | $6.00 | $3.26 | $6.57 | $4.87 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.5% | +1.8% | +0.3% | +0.5% |
LLY leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). MRK leads in 1 (Valuation Metrics). 2 tied.
MRUS vs LLY vs MRK vs ABBV vs JNJ: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MRUS or LLY or MRK or ABBV or JNJ a better buy right now?
For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.
7% revenue growth year-over-year, versus -12. 4% for Merus N. V. (MRUS). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 3x trailing P/E (21. 7x forward), making it the more compelling value choice. Analysts rate Eli Lilly and Company (LLY) a "Buy" — based on 45 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MRUS or LLY or MRK or ABBV or JNJ?
On trailing P/E, Merck & Co.
, Inc. (MRK) is the cheapest at 15. 3x versus AbbVie Inc. at 85. 0x. On forward P/E, AbbVie Inc. is actually cheaper at 14. 2x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Eli Lilly and Company wins at 0. 91x versus Johnson & Johnson's 34. 02x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — MRUS or LLY or MRK or ABBV or JNJ?
Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +399.
3%, compared to +43. 9% for Johnson & Johnson (JNJ). Over 10 years, the gap is even starker: LLY returned +1203% versus JNJ's +131. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MRUS or LLY or MRK or ABBV or JNJ?
By beta (market sensitivity over 5 years), Johnson & Johnson (JNJ) is the lower-risk stock at 0.
04β versus Eli Lilly and Company's 0. 65β — meaning LLY is approximately 1353% more volatile than JNJ relative to the S&P 500. On balance sheet safety, Merus N. V. (MRUS) carries a lower debt/equity ratio of 2% versus 160% for Eli Lilly and Company — giving it more financial flexibility in a downturn.
05Which is growing faster — MRUS or LLY or MRK or ABBV or JNJ?
By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.
7% versus -12. 4% for Merus N. V. (MRUS). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -57. 8% for Johnson & Johnson. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MRUS or LLY or MRK or ABBV or JNJ?
Eli Lilly and Company (LLY) is the more profitable company, earning 31.
7% net margin versus -595. 9% for Merus N. V. — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus -753. 0% for MRUS. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MRUS or LLY or MRK or ABBV or JNJ more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Eli Lilly and Company (LLY) is the more undervalued stock at a PEG of 0. 91x versus Johnson & Johnson's 34. 02x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, AbbVie Inc. (ABBV) trades at 14. 2x forward P/E versus 26. 3x for Eli Lilly and Company — 12. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for LLY: 33. 0% to $1261. 11.
08Which pays a better dividend — MRUS or LLY or MRK or ABBV or JNJ?
In this comparison, ABBV (3.
3% yield), MRK (2. 9% yield), JNJ (2. 2% yield), LLY (0. 6% yield) pay a dividend. MRUS does not pay a meaningful dividend and should not be held primarily for income.
09Is MRUS or LLY or MRK or ABBV or JNJ better for a retirement portfolio?
For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
65), 0. 6% yield, +1203% 10Y return). Both have compounded well over 10 years (LLY: +1203%, MRK: +164. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MRUS and LLY and MRK and ABBV and JNJ?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MRUS is a small-cap quality compounder stock; LLY is a large-cap high-growth stock; MRK is a large-cap deep-value stock; ABBV is a large-cap income-oriented stock; JNJ is a large-cap quality compounder stock. LLY, MRK, ABBV, JNJ pay a dividend while MRUS does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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