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MRVI vs AZTA vs ILMN vs QGEN vs PACB

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MRVI
Maravai LifeSciences Holdings, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$700M
5Y Perf.-82.8%
AZTA
Azenta, Inc.

Medical - Instruments & Supplies

HealthcareNASDAQ • US
Market Cap$885M
5Y Perf.-73.7%
ILMN
Illumina, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$21.55B
5Y Perf.-54.7%
QGEN
Qiagen N.V.

Medical - Diagnostics & Research

HealthcareNYSE • NL
Market Cap$6.81B
5Y Perf.-35.4%
PACB
Pacific Biosciences of California, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$426M
5Y Perf.-91.1%

MRVI vs AZTA vs ILMN vs QGEN vs PACB — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MRVI logoMRVI
AZTA logoAZTA
ILMN logoILMN
QGEN logoQGEN
PACB logoPACB
IndustryBiotechnologyMedical - Instruments & SuppliesMedical - Diagnostics & ResearchMedical - Diagnostics & ResearchMedical - Devices
Market Cap$700M$885M$21.55B$6.81B$426M
Revenue (TTM)$205M$597M$4.39B$2.09B$160M
Net Income (TTM)$-105M$-178M$853M$425M$-129M
Gross Margin29.0%44.6%67.1%61.8%37.1%
Operating Margin21.1%-2.6%20.9%24.9%-101.7%
Forward P/E37.0x27.2x13.5x
Total Debt$36M$111M$2.55B$1.65B$759M
Cash & Equiv.$217M$280M$1.42B$839M$64M

MRVI vs AZTA vs ILMN vs QGEN vs PACBLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MRVI
AZTA
ILMN
QGEN
PACB
StockNov 20May 26Return
Maravai LifeScience… (MRVI)10017.2-82.8%
Azenta, Inc. (AZTA)10026.3-73.7%
Illumina, Inc. (ILMN)10045.3-54.7%
Qiagen N.V. (QGEN)10064.6-35.4%
Pacific Biosciences… (PACB)1008.9-91.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: MRVI vs AZTA vs ILMN vs QGEN vs PACB

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: QGEN leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. Maravai LifeSciences Holdings, Inc. is the stronger pick specifically for recent price momentum and sentiment. ILMN also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
MRVI
Maravai LifeSciences Holdings, Inc.
The Momentum Pick

MRVI is the #2 pick in this set and the best alternative if momentum is your priority.

  • +134.3% vs AZTA's -30.6%
Best for: momentum
AZTA
Azenta, Inc.
The Healthcare Pick

AZTA lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
ILMN
Illumina, Inc.
The Niche Pick

ILMN ranks third and is worth considering specifically for efficiency.

  • 13.4% ROA vs PACB's -16.1%, ROIC 16.8% vs -45.8%
Best for: efficiency
QGEN
Qiagen N.V.
The Income Pick

QGEN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 1 yrs, beta 0.40, yield 0.8%
  • Rev growth 5.7%, EPS growth 436.8%, 3Y rev CAGR -0.8%
  • 63.0% 10Y total return vs AZTA's 130.4%
  • Lower volatility, beta 0.40, Low D/E 43.8%, current ratio 3.90x
Best for: income & stability and growth exposure
PACB
Pacific Biosciences of California, Inc.
The Healthcare Pick

Among these 5 stocks, PACB doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthQGEN logoQGEN5.7% revenue growth vs MRVI's -28.3%
ValueQGEN logoQGENBetter valuation composite
Quality / MarginsQGEN logoQGEN20.3% margin vs PACB's -80.3%
Stability / SafetyQGEN logoQGENBeta 0.40 vs PACB's 2.41, lower leverage
DividendsQGEN logoQGEN0.8% yield; 1-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)MRVI logoMRVI+134.3% vs AZTA's -30.6%
Efficiency (ROA)ILMN logoILMN13.4% ROA vs PACB's -16.1%, ROIC 16.8% vs -45.8%

MRVI vs AZTA vs ILMN vs QGEN vs PACB — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MRVIMaravai LifeSciences Holdings, Inc.
FY 2025
Shipping and Handling
100.0%$4M
AZTAAzenta, Inc.
FY 2025
Service
70.8%$421M
Product
29.2%$173M
ILMNIllumina, Inc.
FY 2025
Sequencing
91.8%$4.0B
Microarray
8.2%$358M
QGENQiagen N.V.
FY 2025
Consumables and Related
44.9%$1.9B
Diagnostic Solutions
19.2%$803M
Sample Technologies
15.8%$661M
PCR / Nucleic Acid Amplification
7.4%$309M
Genomics / NGS
5.8%$242M
Instruments
5.1%$214M
Product and Service, Other
1.8%$75M
PACBPacific Biosciences of California, Inc.
FY 2025
Product
45.9%$136M
Consumable
27.7%$82M
Instrument
18.2%$54M
Service And Other
8.2%$24M

MRVI vs AZTA vs ILMN vs QGEN vs PACB — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLILMNLAGGINGPACB

Income & Cash Flow (Last 12 Months)

Evenly matched — ILMN and QGEN each lead in 2 of 6 comparable metrics.

ILMN is the larger business by revenue, generating $4.4B annually — 27.4x PACB's $160M. QGEN is the more profitable business, keeping 20.3% of every revenue dollar as net income compared to PACB's -80.3%. On growth, MRVI holds the edge at +40.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
RevenueTrailing 12 months$205M$597M$4.4B$2.1B$160M
EBITDAEarnings before interest/tax$100M$41M$1.1B$714M-$151M
Net IncomeAfter-tax profit-$105M-$178M$853M$425M-$129M
Free Cash FlowCash after capex-$52M$29M$989M$453M-$116M
Gross MarginGross profit ÷ Revenue+29.0%+44.6%+67.1%+61.8%+37.1%
Operating MarginEBIT ÷ Revenue+21.1%-2.6%+20.9%+24.9%-101.7%
Net MarginNet income ÷ Revenue-51.1%-29.9%+19.4%+20.3%-80.3%
FCF MarginFCF ÷ Revenue-25.3%+4.8%+22.5%+21.7%-72.6%
Rev. Growth (YoY)Latest quarter vs prior year+40.5%+1.0%+4.8%+3.7%+0.1%
EPS Growth (YoY)Latest quarter vs prior year+87.9%-3.0%+6.1%+26.8%+97.9%
Evenly matched — ILMN and QGEN each lead in 2 of 6 comparable metrics.

Valuation Metrics

Evenly matched — AZTA and QGEN each lead in 3 of 7 comparable metrics.

At 16.2x trailing earnings, QGEN trades at a 38% valuation discount to ILMN's 26.0x P/E. Adjusting for growth (PEG ratio), QGEN offers better value at 0.36x vs ILMN's 6.15x — a lower PEG means you pay less per unit of expected earnings growth.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
Market CapShares × price$700M$885M$21.6B$6.8B$426M
Enterprise ValueMkt cap + debt − cash$519M$717M$22.7B$7.6B$1.1B
Trailing P/EPrice ÷ TTM EPS-5.33x-15.75x26.03x16.20x-0.77x
Forward P/EPrice ÷ next-FY EPS est.36.96x27.22x13.47x
PEG RatioP/E ÷ EPS growth rate6.15x0.36x
EV / EBITDAEnterprise value multiple9.58x14.35x20.01x10.68x
Price / SalesMarket cap ÷ Revenue3.77x1.49x4.97x3.26x2.66x
Price / BookPrice ÷ Book value/share1.89x0.51x8.13x1.82x79.07x
Price / FCFMarket cap ÷ FCF23.10x23.15x15.02x
Evenly matched — AZTA and QGEN each lead in 3 of 7 comparable metrics.

Profitability & Efficiency

ILMN leads this category, winning 5 of 9 comparable metrics.

ILMN delivers a 32.8% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-2 for PACB. AZTA carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to PACB's 141.98x. On the Piotroski fundamental quality scale (0–9), ILMN scores 8/9 vs MRVI's 2/9, reflecting strong financial health.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
ROE (TTM)Return on equity-25.5%-10.7%+32.8%+11.9%-2.5%
ROA (TTM)Return on assets-12.9%-8.8%+13.4%+7.0%-16.1%
ROICReturn on invested capital-1.2%-0.5%+16.8%+8.6%-45.8%
ROCEReturn on capital employed-0.8%-0.6%+17.6%+9.5%-58.0%
Piotroski ScoreFundamental quality 0–926883
Debt / EquityFinancial leverage0.10x0.06x0.94x0.44x141.98x
Net DebtTotal debt minus cash-$181M-$169M$1.1B$815M$696M
Cash & Equiv.Liquid assets$217M$280M$1.4B$839M$64M
Total DebtShort + long-term debt$36M$111M$2.6B$1.7B$759M
Interest CoverageEBIT ÷ Interest expense-6.21x12.09x15.74x-44.67x
ILMN leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

QGEN leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in QGEN five years ago would be worth $7,690 today (with dividends reinvested), compared to $612 for PACB. Over the past 12 months, MRVI leads with a +134.3% total return vs AZTA's -30.6%. The 3-year compound annual growth rate (CAGR) favors QGEN at -7.8% vs PACB's -51.4% — a key indicator of consistent wealth creation.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
YTD ReturnYear-to-date+42.6%-42.4%+5.6%-21.8%-23.4%
1-Year ReturnPast 12 months+134.3%-30.6%+78.3%-15.6%+17.5%
3-Year ReturnCumulative with dividends-65.1%-57.7%-25.4%-21.7%-88.5%
5-Year ReturnCumulative with dividends-86.5%-78.2%-61.6%-23.1%-93.9%
10-Year ReturnCumulative with dividends-83.8%+130.4%+3.0%+63.0%-84.0%
CAGR (3Y)Annualised 3-year return-29.6%-24.9%-9.3%-7.8%-51.4%
QGEN leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — MRVI and QGEN each lead in 1 of 2 comparable metrics.

QGEN is the less volatile stock with a 0.40 beta — it tends to amplify market swings less than PACB's 2.41 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRVI currently trades 98.0% from its 52-week high vs AZTA's 46.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
Beta (5Y)Sensitivity to S&P 5002.13x1.91x1.20x0.40x2.41x
52-Week HighHighest price in past year$4.95$41.73$155.53$57.82$2.73
52-Week LowLowest price in past year$1.95$17.11$75.24$32.92$0.85
% of 52W HighCurrent price vs 52-week peak+98.0%+46.1%+91.2%+57.1%+51.6%
RSI (14)Momentum oscillator 0–10067.732.059.526.555.7
Avg Volume (50D)Average daily shares traded2.0M1.0M1.5M1.9M6.0M
Evenly matched — MRVI and QGEN each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — MRVI and QGEN each lead in 1 of 1 comparable metric.

Analyst consensus: MRVI as "Buy", AZTA as "Buy", ILMN as "Buy", QGEN as "Hold", PACB as "Buy". Consensus price targets imply 132.4% upside for AZTA (target: $45) vs -29.1% for PACB (target: $1). QGEN is the only dividend payer here at 0.79% yield — a key consideration for income-focused portfolios.

MetricMRVI logoMRVIMaravai LifeScien…AZTA logoAZTAAzenta, Inc.ILMN logoILMNIllumina, Inc.QGEN logoQGENQiagen N.V.PACB logoPACBPacific Bioscienc…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHoldBuy
Price TargetConsensus 12-month target$5.25$44.67$147.38$47.50$1.00
# AnalystsCovering analysts1412503018
Dividend YieldAnnual dividend ÷ price+0.8%
Dividend StreakConsecutive years of raises101
Dividend / ShareAnnual DPS$0.26
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+3.4%+4.5%0.0%
Evenly matched — MRVI and QGEN each lead in 1 of 1 comparable metric.
Key Takeaway

ILMN leads in 1 of 6 categories (Profitability & Efficiency). QGEN leads in 1 (Total Returns). 4 tied.

Best OverallIllumina, Inc. (ILMN)Leads 1 of 6 categories
Loading custom metrics...

MRVI vs AZTA vs ILMN vs QGEN vs PACB: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is MRVI or AZTA or ILMN or QGEN or PACB a better buy right now?

For growth investors, Qiagen N.

V. (QGEN) is the stronger pick with 5. 7% revenue growth year-over-year, versus -28. 3% for Maravai LifeSciences Holdings, Inc. (MRVI). Qiagen N. V. (QGEN) offers the better valuation at 16. 2x trailing P/E (13. 5x forward), making it the more compelling value choice. Analysts rate Maravai LifeSciences Holdings, Inc. (MRVI) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MRVI or AZTA or ILMN or QGEN or PACB?

On trailing P/E, Qiagen N.

V. (QGEN) is the cheapest at 16. 2x versus Illumina, Inc. at 26. 0x. On forward P/E, Qiagen N. V. is actually cheaper at 13. 5x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Qiagen N. V. wins at 0. 30x versus Illumina, Inc. 's 6. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — MRVI or AZTA or ILMN or QGEN or PACB?

Over the past 5 years, Qiagen N.

V. (QGEN) delivered a total return of -23. 1%, compared to -93. 9% for Pacific Biosciences of California, Inc. (PACB). Over 10 years, the gap is even starker: AZTA returned +130. 4% versus PACB's -84. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MRVI or AZTA or ILMN or QGEN or PACB?

By beta (market sensitivity over 5 years), Qiagen N.

V. (QGEN) is the lower-risk stock at 0. 40β versus Pacific Biosciences of California, Inc. 's 2. 41β — meaning PACB is approximately 495% more volatile than QGEN relative to the S&P 500. On balance sheet safety, Azenta, Inc. (AZTA) carries a lower debt/equity ratio of 6% versus 142% for Pacific Biosciences of California, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — MRVI or AZTA or ILMN or QGEN or PACB?

By revenue growth (latest reported year), Qiagen N.

V. (QGEN) is pulling ahead at 5. 7% versus -28. 3% for Maravai LifeSciences Holdings, Inc. (MRVI). On earnings-per-share growth, the picture is similar: Qiagen N. V. grew EPS 436. 8% year-over-year, compared to -70. 1% for Pacific Biosciences of California, Inc.. Over a 3-year CAGR, PACB leads at 7. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MRVI or AZTA or ILMN or QGEN or PACB?

Qiagen N.

V. (QGEN) is the more profitable company, earning 20. 3% net margin versus -341. 5% for Pacific Biosciences of California, Inc. — meaning it keeps 20. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: QGEN leads at 24. 9% versus -348. 5% for PACB. At the gross margin level — before operating expenses — ILMN leads at 66. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is MRVI or AZTA or ILMN or QGEN or PACB more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Qiagen N. V. (QGEN) is the more undervalued stock at a PEG of 0. 30x versus Illumina, Inc. 's 6. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Qiagen N. V. (QGEN) trades at 13. 5x forward P/E versus 37. 0x for Azenta, Inc. — 23. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AZTA: 132. 4% to $44. 67.

08

Which pays a better dividend — MRVI or AZTA or ILMN or QGEN or PACB?

In this comparison, QGEN (0.

8% yield) pays a dividend. MRVI, AZTA, ILMN, PACB do not pay a meaningful dividend and should not be held primarily for income.

09

Is MRVI or AZTA or ILMN or QGEN or PACB better for a retirement portfolio?

For long-horizon retirement investors, Qiagen N.

V. (QGEN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 40), 0. 8% yield). Pacific Biosciences of California, Inc. (PACB) carries a higher beta of 2. 41 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (QGEN: +63. 0%, PACB: -84. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between MRVI and AZTA and ILMN and QGEN and PACB?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: MRVI is a small-cap quality compounder stock; AZTA is a small-cap quality compounder stock; ILMN is a mid-cap quality compounder stock; QGEN is a small-cap deep-value stock; PACB is a small-cap quality compounder stock. QGEN pays a dividend while MRVI, AZTA, ILMN, PACB do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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