Biotechnology
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5 / 10Stock Comparison
MRVI vs AZTA vs ILMN vs QGEN vs PACB
Revenue, margins, valuation, and 5-year total return — side by side.
Medical - Instruments & Supplies
Medical - Diagnostics & Research
Medical - Diagnostics & Research
Medical - Devices
MRVI vs AZTA vs ILMN vs QGEN vs PACB — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Medical - Instruments & Supplies | Medical - Diagnostics & Research | Medical - Diagnostics & Research | Medical - Devices |
| Market Cap | $700M | $885M | $21.55B | $6.81B | $426M |
| Revenue (TTM) | $205M | $597M | $4.39B | $2.09B | $160M |
| Net Income (TTM) | $-105M | $-178M | $853M | $425M | $-129M |
| Gross Margin | 29.0% | 44.6% | 67.1% | 61.8% | 37.1% |
| Operating Margin | 21.1% | -2.6% | 20.9% | 24.9% | -101.7% |
| Forward P/E | — | 37.0x | 27.2x | 13.5x | — |
| Total Debt | $36M | $111M | $2.55B | $1.65B | $759M |
| Cash & Equiv. | $217M | $280M | $1.42B | $839M | $64M |
MRVI vs AZTA vs ILMN vs QGEN vs PACB — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Nov 20 | May 26 | Return |
|---|---|---|---|
| Maravai LifeScience… (MRVI) | 100 | 17.2 | -82.8% |
| Azenta, Inc. (AZTA) | 100 | 26.3 | -73.7% |
| Illumina, Inc. (ILMN) | 100 | 45.3 | -54.7% |
| Qiagen N.V. (QGEN) | 100 | 64.6 | -35.4% |
| Pacific Biosciences… (PACB) | 100 | 8.9 | -91.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: MRVI vs AZTA vs ILMN vs QGEN vs PACB
Each card shows where this stock fits in a portfolio — not just who wins on paper.
MRVI is the #2 pick in this set and the best alternative if momentum is your priority.
- +134.3% vs AZTA's -30.6%
AZTA lags the leaders in this set but could rank higher in a more targeted comparison.
ILMN ranks third and is worth considering specifically for efficiency.
- 13.4% ROA vs PACB's -16.1%, ROIC 16.8% vs -45.8%
QGEN carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 1 yrs, beta 0.40, yield 0.8%
- Rev growth 5.7%, EPS growth 436.8%, 3Y rev CAGR -0.8%
- 63.0% 10Y total return vs AZTA's 130.4%
- Lower volatility, beta 0.40, Low D/E 43.8%, current ratio 3.90x
Among these 5 stocks, PACB doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 5.7% revenue growth vs MRVI's -28.3% | |
| Value | Better valuation composite | |
| Quality / Margins | 20.3% margin vs PACB's -80.3% | |
| Stability / Safety | Beta 0.40 vs PACB's 2.41, lower leverage | |
| Dividends | 0.8% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +134.3% vs AZTA's -30.6% | |
| Efficiency (ROA) | 13.4% ROA vs PACB's -16.1%, ROIC 16.8% vs -45.8% |
MRVI vs AZTA vs ILMN vs QGEN vs PACB — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
MRVI vs AZTA vs ILMN vs QGEN vs PACB — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ILMN leads in 1 of 6 categories
QGEN leads 1 • MRVI leads 0 • AZTA leads 0 • PACB leads 0 • 4 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ILMN and QGEN each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ILMN is the larger business by revenue, generating $4.4B annually — 27.4x PACB's $160M. QGEN is the more profitable business, keeping 20.3% of every revenue dollar as net income compared to PACB's -80.3%. On growth, MRVI holds the edge at +40.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $205M | $597M | $4.4B | $2.1B | $160M |
| EBITDAEarnings before interest/tax | $100M | $41M | $1.1B | $714M | -$151M |
| Net IncomeAfter-tax profit | -$105M | -$178M | $853M | $425M | -$129M |
| Free Cash FlowCash after capex | -$52M | $29M | $989M | $453M | -$116M |
| Gross MarginGross profit ÷ Revenue | +29.0% | +44.6% | +67.1% | +61.8% | +37.1% |
| Operating MarginEBIT ÷ Revenue | +21.1% | -2.6% | +20.9% | +24.9% | -101.7% |
| Net MarginNet income ÷ Revenue | -51.1% | -29.9% | +19.4% | +20.3% | -80.3% |
| FCF MarginFCF ÷ Revenue | -25.3% | +4.8% | +22.5% | +21.7% | -72.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | +40.5% | +1.0% | +4.8% | +3.7% | +0.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +87.9% | -3.0% | +6.1% | +26.8% | +97.9% |
Valuation Metrics
Evenly matched — AZTA and QGEN each lead in 3 of 7 comparable metrics.
Valuation Metrics
At 16.2x trailing earnings, QGEN trades at a 38% valuation discount to ILMN's 26.0x P/E. Adjusting for growth (PEG ratio), QGEN offers better value at 0.36x vs ILMN's 6.15x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $700M | $885M | $21.6B | $6.8B | $426M |
| Enterprise ValueMkt cap + debt − cash | $519M | $717M | $22.7B | $7.6B | $1.1B |
| Trailing P/EPrice ÷ TTM EPS | -5.33x | -15.75x | 26.03x | 16.20x | -0.77x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 36.96x | 27.22x | 13.47x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | 6.15x | 0.36x | — |
| EV / EBITDAEnterprise value multiple | 9.58x | 14.35x | 20.01x | 10.68x | — |
| Price / SalesMarket cap ÷ Revenue | 3.77x | 1.49x | 4.97x | 3.26x | 2.66x |
| Price / BookPrice ÷ Book value/share | 1.89x | 0.51x | 8.13x | 1.82x | 79.07x |
| Price / FCFMarket cap ÷ FCF | — | 23.10x | 23.15x | 15.02x | — |
Profitability & Efficiency
ILMN leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
ILMN delivers a 32.8% return on equity — every $100 of shareholder capital generates $33 in annual profit, vs $-2 for PACB. AZTA carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to PACB's 141.98x. On the Piotroski fundamental quality scale (0–9), ILMN scores 8/9 vs MRVI's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -25.5% | -10.7% | +32.8% | +11.9% | -2.5% |
| ROA (TTM)Return on assets | -12.9% | -8.8% | +13.4% | +7.0% | -16.1% |
| ROICReturn on invested capital | -1.2% | -0.5% | +16.8% | +8.6% | -45.8% |
| ROCEReturn on capital employed | -0.8% | -0.6% | +17.6% | +9.5% | -58.0% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 6 | 8 | 8 | 3 |
| Debt / EquityFinancial leverage | 0.10x | 0.06x | 0.94x | 0.44x | 141.98x |
| Net DebtTotal debt minus cash | -$181M | -$169M | $1.1B | $815M | $696M |
| Cash & Equiv.Liquid assets | $217M | $280M | $1.4B | $839M | $64M |
| Total DebtShort + long-term debt | $36M | $111M | $2.6B | $1.7B | $759M |
| Interest CoverageEBIT ÷ Interest expense | -6.21x | — | 12.09x | 15.74x | -44.67x |
Total Returns (Dividends Reinvested)
QGEN leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in QGEN five years ago would be worth $7,690 today (with dividends reinvested), compared to $612 for PACB. Over the past 12 months, MRVI leads with a +134.3% total return vs AZTA's -30.6%. The 3-year compound annual growth rate (CAGR) favors QGEN at -7.8% vs PACB's -51.4% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +42.6% | -42.4% | +5.6% | -21.8% | -23.4% |
| 1-Year ReturnPast 12 months | +134.3% | -30.6% | +78.3% | -15.6% | +17.5% |
| 3-Year ReturnCumulative with dividends | -65.1% | -57.7% | -25.4% | -21.7% | -88.5% |
| 5-Year ReturnCumulative with dividends | -86.5% | -78.2% | -61.6% | -23.1% | -93.9% |
| 10-Year ReturnCumulative with dividends | -83.8% | +130.4% | +3.0% | +63.0% | -84.0% |
| CAGR (3Y)Annualised 3-year return | -29.6% | -24.9% | -9.3% | -7.8% | -51.4% |
Risk & Volatility
Evenly matched — MRVI and QGEN each lead in 1 of 2 comparable metrics.
Risk & Volatility
QGEN is the less volatile stock with a 0.40 beta — it tends to amplify market swings less than PACB's 2.41 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRVI currently trades 98.0% from its 52-week high vs AZTA's 46.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.13x | 1.91x | 1.20x | 0.40x | 2.41x |
| 52-Week HighHighest price in past year | $4.95 | $41.73 | $155.53 | $57.82 | $2.73 |
| 52-Week LowLowest price in past year | $1.95 | $17.11 | $75.24 | $32.92 | $0.85 |
| % of 52W HighCurrent price vs 52-week peak | +98.0% | +46.1% | +91.2% | +57.1% | +51.6% |
| RSI (14)Momentum oscillator 0–100 | 67.7 | 32.0 | 59.5 | 26.5 | 55.7 |
| Avg Volume (50D)Average daily shares traded | 2.0M | 1.0M | 1.5M | 1.9M | 6.0M |
Analyst Outlook
Evenly matched — MRVI and QGEN each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: MRVI as "Buy", AZTA as "Buy", ILMN as "Buy", QGEN as "Hold", PACB as "Buy". Consensus price targets imply 132.4% upside for AZTA (target: $45) vs -29.1% for PACB (target: $1). QGEN is the only dividend payer here at 0.79% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Hold | Buy |
| Price TargetConsensus 12-month target | $5.25 | $44.67 | $147.38 | $47.50 | $1.00 |
| # AnalystsCovering analysts | 14 | 12 | 50 | 30 | 18 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | +0.8% | — |
| Dividend StreakConsecutive years of raises | 1 | 0 | — | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | $0.26 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +3.4% | +4.5% | 0.0% |
ILMN leads in 1 of 6 categories (Profitability & Efficiency). QGEN leads in 1 (Total Returns). 4 tied.
MRVI vs AZTA vs ILMN vs QGEN vs PACB: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is MRVI or AZTA or ILMN or QGEN or PACB a better buy right now?
For growth investors, Qiagen N.
V. (QGEN) is the stronger pick with 5. 7% revenue growth year-over-year, versus -28. 3% for Maravai LifeSciences Holdings, Inc. (MRVI). Qiagen N. V. (QGEN) offers the better valuation at 16. 2x trailing P/E (13. 5x forward), making it the more compelling value choice. Analysts rate Maravai LifeSciences Holdings, Inc. (MRVI) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — MRVI or AZTA or ILMN or QGEN or PACB?
On trailing P/E, Qiagen N.
V. (QGEN) is the cheapest at 16. 2x versus Illumina, Inc. at 26. 0x. On forward P/E, Qiagen N. V. is actually cheaper at 13. 5x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Qiagen N. V. wins at 0. 30x versus Illumina, Inc. 's 6. 43x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — MRVI or AZTA or ILMN or QGEN or PACB?
Over the past 5 years, Qiagen N.
V. (QGEN) delivered a total return of -23. 1%, compared to -93. 9% for Pacific Biosciences of California, Inc. (PACB). Over 10 years, the gap is even starker: AZTA returned +130. 4% versus PACB's -84. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — MRVI or AZTA or ILMN or QGEN or PACB?
By beta (market sensitivity over 5 years), Qiagen N.
V. (QGEN) is the lower-risk stock at 0. 40β versus Pacific Biosciences of California, Inc. 's 2. 41β — meaning PACB is approximately 495% more volatile than QGEN relative to the S&P 500. On balance sheet safety, Azenta, Inc. (AZTA) carries a lower debt/equity ratio of 6% versus 142% for Pacific Biosciences of California, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — MRVI or AZTA or ILMN or QGEN or PACB?
By revenue growth (latest reported year), Qiagen N.
V. (QGEN) is pulling ahead at 5. 7% versus -28. 3% for Maravai LifeSciences Holdings, Inc. (MRVI). On earnings-per-share growth, the picture is similar: Qiagen N. V. grew EPS 436. 8% year-over-year, compared to -70. 1% for Pacific Biosciences of California, Inc.. Over a 3-year CAGR, PACB leads at 7. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — MRVI or AZTA or ILMN or QGEN or PACB?
Qiagen N.
V. (QGEN) is the more profitable company, earning 20. 3% net margin versus -341. 5% for Pacific Biosciences of California, Inc. — meaning it keeps 20. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: QGEN leads at 24. 9% versus -348. 5% for PACB. At the gross margin level — before operating expenses — ILMN leads at 66. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is MRVI or AZTA or ILMN or QGEN or PACB more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Qiagen N. V. (QGEN) is the more undervalued stock at a PEG of 0. 30x versus Illumina, Inc. 's 6. 43x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Qiagen N. V. (QGEN) trades at 13. 5x forward P/E versus 37. 0x for Azenta, Inc. — 23. 5x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AZTA: 132. 4% to $44. 67.
08Which pays a better dividend — MRVI or AZTA or ILMN or QGEN or PACB?
In this comparison, QGEN (0.
8% yield) pays a dividend. MRVI, AZTA, ILMN, PACB do not pay a meaningful dividend and should not be held primarily for income.
09Is MRVI or AZTA or ILMN or QGEN or PACB better for a retirement portfolio?
For long-horizon retirement investors, Qiagen N.
V. (QGEN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 40), 0. 8% yield). Pacific Biosciences of California, Inc. (PACB) carries a higher beta of 2. 41 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (QGEN: +63. 0%, PACB: -84. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between MRVI and AZTA and ILMN and QGEN and PACB?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: MRVI is a small-cap quality compounder stock; AZTA is a small-cap quality compounder stock; ILMN is a mid-cap quality compounder stock; QGEN is a small-cap deep-value stock; PACB is a small-cap quality compounder stock. QGEN pays a dividend while MRVI, AZTA, ILMN, PACB do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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