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MXCT vs NVAX vs MRNA vs BTBT vs BNTX

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
MXCT
MaxCyte, Inc.

Medical - Devices

HealthcareNASDAQ • US
Market Cap$93M
5Y Perf.-94.9%
NVAX
Novavax, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.50B
5Y Perf.-94.9%
MRNA
Moderna, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$19.25B
5Y Perf.-86.3%
BTBT
Bit Digital, Inc.

Financial - Capital Markets

Financial ServicesNASDAQ • US
Market Cap$589M
5Y Perf.-79.7%
BNTX
BioNTech SE

Biotechnology

HealthcareNASDAQ • DE
Market Cap$23.52B
5Y Perf.-71.7%

MXCT vs NVAX vs MRNA vs BTBT vs BNTX — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
MXCT logoMXCT
NVAX logoNVAX
MRNA logoMRNA
BTBT logoBTBT
BNTX logoBNTX
IndustryMedical - DevicesBiotechnologyBiotechnologyFinancial - Capital MarketsBiotechnology
Market Cap$93M$1.50B$19.25B$589M$23.52B
Revenue (TTM)$33M$596M$2.23B$164M$2.86B
Net Income (TTM)$-45M$-88M$-3.19B$137M$-1.13B
Gross Margin81.2%84.6%-13.9%61.9%77.7%
Operating Margin-138.3%-11.2%-153.3%16.8%-45.9%
Forward P/E3.6x9.2x
Total Debt$18M$249M$1.92B$14M$267M
Cash & Equiv.$20M$241M$2.60B$95M$7.67B

MXCT vs NVAX vs MRNA vs BTBT vs BNTXLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

MXCT
NVAX
MRNA
BTBT
BNTX
StockJul 21May 26Return
MaxCyte, Inc. (MXCT)1005.1-94.9%
Novavax, Inc. (NVAX)1005.1-94.9%
Moderna, Inc. (MRNA)10013.7-86.3%
Bit Digital, Inc. (BTBT)10020.3-79.7%
BioNTech SE (BNTX)10028.3-71.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: MXCT vs NVAX vs MRNA vs BTBT vs BNTX

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: BTBT leads in 4 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. Novavax, Inc. is the stronger pick specifically for valuation and capital efficiency. MRNA and BNTX also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
MXCT
MaxCyte, Inc.
The Healthcare Pick

Among these 5 stocks, MXCT doesn't own a clear edge in any measured category.

Best for: healthcare exposure
NVAX
Novavax, Inc.
The Growth Play

NVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
  • Better valuation composite
Best for: growth exposure
MRNA
Moderna, Inc.
The Momentum Pick

MRNA ranks third and is worth considering specifically for momentum.

  • +101.7% vs MXCT's -68.2%
Best for: momentum
BTBT
Bit Digital, Inc.
The Banking Pick

BTBT carries the broadest edge in this set and is the clearest fit for growth and quality.

  • 264.6% NII/revenue growth vs MRNA's -39.2%
  • 17.3% margin vs MRNA's -143.6%
  • 0.3% yield; the other 4 pay no meaningful dividend
  • 19.0% ROA vs MRNA's -26.6%, ROIC 6.5% vs -26.1%
Best for: growth and quality
BNTX
BioNTech SE
The Income Pick

BNTX is the clearest fit if your priority is income & stability and long-term compounding.

  • Dividend streak 1 yrs, beta 1.14
  • 5.7% 10Y total return vs MRNA's 161.0%
  • Lower volatility, beta 1.14, Low D/E 1.4%, current ratio 7.54x
  • Beta 1.14, current ratio 7.54x
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthBTBT logoBTBT264.6% NII/revenue growth vs MRNA's -39.2%
ValueNVAX logoNVAXBetter valuation composite
Quality / MarginsBTBT logoBTBT17.3% margin vs MRNA's -143.6%
Stability / SafetyBNTX logoBNTXBeta 1.14 vs BTBT's 3.37, lower leverage
DividendsBTBT logoBTBT0.3% yield; the other 4 pay no meaningful dividend
Momentum (1Y)MRNA logoMRNA+101.7% vs MXCT's -68.2%
Efficiency (ROA)BTBT logoBTBT19.0% ROA vs MRNA's -26.6%, ROIC 6.5% vs -26.1%

MXCT vs NVAX vs MRNA vs BTBT vs BNTX — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

MXCTMaxCyte, Inc.
FY 2024
Product
94.9%$21M
Product and Service, Other
5.1%$1M
NVAXNovavax, Inc.
FY 2025
Product
50.0%$685M
Nuvaxovid Sales
45.6%$625M
Supply Sales
4.4%$60M
MRNAModerna, Inc.
FY 2025
Product Sales
100.0%$3.3B
BTBTBit Digital, Inc.
FY 2024
Other Member
100.0%$550,260
BNTXBioNTech SE
FY 2025
Other Sales
100.0%$262M

MXCT vs NVAX vs MRNA vs BTBT vs BNTX — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLBTBTLAGGINGBNTX

Income & Cash Flow (Last 12 Months)

BTBT leads this category, winning 3 of 6 comparable metrics.

BNTX is the larger business by revenue, generating $2.9B annually — 86.6x MXCT's $33M. BTBT is the more profitable business, keeping 17.3% of every revenue dollar as net income compared to MRNA's -143.6%. On growth, MRNA holds the edge at +2.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
RevenueTrailing 12 months$33M$596M$2.2B$164M$2.9B
EBITDAEarnings before interest/tax-$41M-$47M-$3.2B$166M-$931M
Net IncomeAfter-tax profit-$45M-$88M-$3.2B$137M-$1.1B
Free Cash FlowCash after capex-$36M-$96M-$1.6B-$448M$277M
Gross MarginGross profit ÷ Revenue+81.2%+84.6%-13.9%+61.9%+77.7%
Operating MarginEBIT ÷ Revenue-138.3%-11.2%-153.3%+16.8%-45.9%
Net MarginNet income ÷ Revenue-135.1%-14.7%-143.6%+17.3%-39.6%
FCF MarginFCF ÷ Revenue-109.5%-16.1%-71.1%-65.3%+9.7%
Rev. Growth (YoY)Latest quarter vs prior year-16.0%-79.1%+2.6%-24.5%
EPS Growth (YoY)Latest quarter vs prior year0.0%-102.0%-34.9%+2.8%-2.1%
BTBT leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

NVAX leads this category, winning 2 of 4 comparable metrics.

At 3.6x trailing earnings, NVAX trades at a 60% valuation discount to BTBT's 9.2x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than BTBT's 8.5x.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
Market CapShares × price$93M$1.5B$19.3B$589M$23.5B
Enterprise ValueMkt cap + debt − cash$91M$1.5B$18.6B$508M$14.8B
Trailing P/EPrice ÷ TTM EPS-2.08x3.63x-6.69x9.15x-17.55x
Forward P/EPrice ÷ next-FY EPS est.
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple2.56x8.49x
Price / SalesMarket cap ÷ Revenue2.81x1.34x9.90x3.60x7.26x
Price / BookPrice ÷ Book value/share0.54x2.18x0.56x1.00x
Price / FCFMarket cap ÷ FCF74.19x
NVAX leads this category, winning 2 of 4 comparable metrics.

Profitability & Efficiency

BTBT leads this category, winning 5 of 9 comparable metrics.

BTBT delivers a 21.4% return on equity — every $100 of shareholder capital generates $21 in annual profit, vs $-37 for MRNA. BNTX carries lower financial leverage with a 0.01x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRNA's 0.22x. On the Piotroski fundamental quality scale (0–9), BTBT scores 6/9 vs MXCT's 2/9, reflecting solid financial health.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
ROE (TTM)Return on equity-24.1%-36.7%+21.4%-6.0%
ROA (TTM)Return on assets-20.6%-7.4%-26.6%+19.0%-5.3%
ROICReturn on invested capital-18.7%-26.1%+6.5%-4.3%
ROCEReturn on capital employed-22.2%+100.4%-27.6%+8.5%-3.1%
Piotroski ScoreFundamental quality 0–925364
Debt / EquityFinancial leverage0.10x0.22x0.03x0.01x
Net DebtTotal debt minus cash-$2M$8M-$679M-$81M-$7.4B
Cash & Equiv.Liquid assets$20M$241M$2.6B$95M$7.7B
Total DebtShort + long-term debt$18M$249M$1.9B$14M$267M
Interest CoverageEBIT ÷ Interest expense-5.10x-1803.00x-62.15x
BTBT leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

Evenly matched — NVAX and MRNA and BNTX each lead in 2 of 6 comparable metrics.

A $10,000 investment in BNTX five years ago would be worth $5,178 today (with dividends reinvested), compared to $513 for MXCT. Over the past 12 months, MRNA leads with a +101.7% total return vs MXCT's -68.2%. The 3-year compound annual growth rate (CAGR) favors NVAX at 7.4% vs MXCT's -43.1% — a key indicator of consistent wealth creation.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
YTD ReturnYear-to-date-43.8%+29.5%+57.3%-10.3%-3.8%
1-Year ReturnPast 12 months-68.2%+55.1%+101.7%-9.0%+0.2%
3-Year ReturnCumulative with dividends-81.6%+23.9%-63.2%-19.7%-13.9%
5-Year ReturnCumulative with dividends-94.9%-94.8%-70.2%-84.6%-48.2%
10-Year ReturnCumulative with dividends-94.9%-90.4%+161.0%-60.4%+568.1%
CAGR (3Y)Annualised 3-year return-43.1%+7.4%-28.3%-7.1%-4.9%
Evenly matched — NVAX and MRNA and BNTX each lead in 2 of 6 comparable metrics.

Risk & Volatility

Evenly matched — MRNA and BNTX each lead in 1 of 2 comparable metrics.

BNTX is the less volatile stock with a 1.14 beta — it tends to amplify market swings less than BTBT's 3.37 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRNA currently trades 81.5% from its 52-week high vs MXCT's 30.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
Beta (5Y)Sensitivity to S&P 5001.44x2.11x1.82x3.37x1.14x
52-Week HighHighest price in past year$2.86$11.97$59.55$4.55$124.00
52-Week LowLowest price in past year$0.66$5.80$22.28$1.25$79.52
% of 52W HighCurrent price vs 52-week peak+30.5%+77.1%+81.5%+40.2%+75.0%
RSI (14)Momentum oscillator 0–10052.264.447.069.143.3
Avg Volume (50D)Average daily shares traded847K4.4M6.9M18.5M1.2M
Evenly matched — MRNA and BNTX each lead in 1 of 2 comparable metrics.

Analyst Outlook

Evenly matched — NVAX and BNTX each lead in 1 of 1 comparable metric.

Analyst consensus: NVAX as "Buy", MRNA as "Hold", BTBT as "Buy", BNTX as "Buy". Consensus price targets imply 173.2% upside for BTBT (target: $5) vs -25.8% for MRNA (target: $36). BTBT is the only dividend payer here at 0.31% yield — a key consideration for income-focused portfolios.

MetricMXCT logoMXCTMaxCyte, Inc.NVAX logoNVAXNovavax, Inc.MRNA logoMRNAModerna, Inc.BTBT logoBTBTBit Digital, Inc.BNTX logoBNTXBioNTech SE
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuy
Price TargetConsensus 12-month target$18.00$36.00$5.00$137.13
# AnalystsCovering analysts2327224
Dividend YieldAnnual dividend ÷ price+0.3%
Dividend StreakConsecutive years of raises1001
Dividend / ShareAnnual DPS$0.01
Buyback YieldShare repurchases ÷ mkt cap+0.2%+0.3%0.0%0.0%0.0%
Evenly matched — NVAX and BNTX each lead in 1 of 1 comparable metric.
Key Takeaway

BTBT leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVAX leads in 1 (Valuation Metrics). 3 tied.

Best OverallBit Digital, Inc. (BTBT)Leads 2 of 6 categories
Loading custom metrics...

MXCT vs NVAX vs MRNA vs BTBT vs BNTX: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is MXCT or NVAX or MRNA or BTBT or BNTX a better buy right now?

For growth investors, Bit Digital, Inc.

(BTBT) is the stronger pick with 264. 6% revenue growth year-over-year, versus -39. 2% for Moderna, Inc. (MRNA). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Novavax, Inc. (NVAX) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — MXCT or NVAX or MRNA or BTBT or BNTX?

On trailing P/E, Novavax, Inc.

(NVAX) is the cheapest at 3. 6x versus Bit Digital, Inc. at 9. 2x.

03

Which is the better long-term investment — MXCT or NVAX or MRNA or BTBT or BNTX?

Over the past 5 years, BioNTech SE (BNTX) delivered a total return of -48.

2%, compared to -94. 9% for MaxCyte, Inc. (MXCT). Over 10 years, the gap is even starker: BNTX returned +568. 1% versus MXCT's -94. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — MXCT or NVAX or MRNA or BTBT or BNTX?

By beta (market sensitivity over 5 years), BioNTech SE (BNTX) is the lower-risk stock at 1.

14β versus Bit Digital, Inc. 's 3. 37β — meaning BTBT is approximately 195% more volatile than BNTX relative to the S&P 500. On balance sheet safety, BioNTech SE (BNTX) carries a lower debt/equity ratio of 1% versus 22% for Moderna, Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — MXCT or NVAX or MRNA or BTBT or BNTX?

By revenue growth (latest reported year), Bit Digital, Inc.

(BTBT) is pulling ahead at 264. 6% versus -39. 2% for Moderna, Inc. (MRNA). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -62. 8% for BioNTech SE. Over a 3-year CAGR, MXCT leads at -9. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — MXCT or NVAX or MRNA or BTBT or BNTX?

Novavax, Inc.

(NVAX) is the more profitable company, earning 39. 2% net margin versus -145. 2% for Moderna, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -158. 1% for MRNA. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Which pays a better dividend — MXCT or NVAX or MRNA or BTBT or BNTX?

In this comparison, BTBT (0.

3% yield) pays a dividend. MXCT, NVAX, MRNA, BNTX do not pay a meaningful dividend and should not be held primarily for income.

08

Is MXCT or NVAX or MRNA or BTBT or BNTX better for a retirement portfolio?

For long-horizon retirement investors, BioNTech SE (BNTX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.

14), +568. 1% 10Y return). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BNTX: +568. 1%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between MXCT and NVAX and MRNA and BTBT and BNTX?

These companies operate in different sectors (MXCT (Healthcare) and NVAX (Healthcare) and MRNA (Healthcare) and BTBT (Financial Services) and BNTX (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: MXCT is a small-cap quality compounder stock; NVAX is a small-cap high-growth stock; MRNA is a mid-cap quality compounder stock; BTBT is a small-cap high-growth stock; BNTX is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

Find Stocks Like These

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Stocks Like

MXCT

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 48%
Run This Screen
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NVAX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 50%
Run This Screen
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MRNA

High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 131%
Run This Screen
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BTBT

High-Growth Compounder

  • Sector: Financial Services
  • Market Cap > $100B
  • Revenue Growth > 132%
  • Net Margin > 10%
Run This Screen
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BNTX

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 46%
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Revenue Growth>
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(MXCT: -16.0% · NVAX: -79.1%)

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