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ORIC vs DBVT vs IMVT vs AGEN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
ORIC vs DBVT vs IMVT vs AGEN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $912M | $1712.35T | $5.53B | $132M |
| Revenue (TTM) | $0.00 | $0.00 | $0.00 | $114M |
| Net Income (TTM) | $-135M | $-168M | $-464M | $115K |
| Gross Margin | — | — | — | 35.7% |
| Operating Margin | — | — | — | -17.7% |
| Forward P/E | — | — | — | 1.8x |
| Total Debt | $12M | $22M | $98K | $10M |
| Cash & Equiv. | $46M | $194M | $714M | $3M |
ORIC vs DBVT vs IMVT vs AGEN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| ORIC Pharmaceutical… (ORIC) | 100 | 30.4 | -69.6% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| Agenus Inc. (AGEN) | 100 | 5.0 | -95.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ORIC vs DBVT vs IMVT vs AGEN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ORIC is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.
- Lower volatility, beta 1.12, Low D/E 3.0%, current ratio 14.13x
- Beta 1.12, current ratio 14.13x
- Beta 1.12 vs AGEN's 2.72
DBVT is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.26
- +110.4% vs AGEN's +27.1%
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs ORIC's -65.8%
- 3.2% margin vs AGEN's 0.1%
AGEN carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 10.4%, EPS growth 100.0%, 3Y rev CAGR 5.2%
- 10.4% revenue growth vs DBVT's -100.0%
- 0.1% ROA vs DBVT's -89.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 10.4% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 3.2% margin vs AGEN's 0.1% | |
| Stability / Safety | Beta 1.12 vs AGEN's 2.72 | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +110.4% vs AGEN's +27.1% | |
| Efficiency (ROA) | 0.1% ROA vs DBVT's -89.0% |
ORIC vs DBVT vs IMVT vs AGEN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
ORIC vs DBVT vs IMVT vs AGEN — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
DBVT leads in 1 of 6 categories
AGEN leads 1 • ORIC leads 0 • IMVT leads 0 • 4 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
DBVT leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
AGEN and IMVT operate at a comparable scale, with $114M and $0 in trailing revenue.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $0 | $114M |
| EBITDAEarnings before interest/tax | -$149M | -$112M | -$487M | -$10M |
| Net IncomeAfter-tax profit | -$135M | -$168M | -$464M | $115,000 |
| Free Cash FlowCash after capex | -$111M | -$151M | -$423M | -$159M |
| Gross MarginGross profit ÷ Revenue | — | — | — | +35.7% |
| Operating MarginEBIT ÷ Revenue | — | — | — | -17.7% |
| Net MarginNet income ÷ Revenue | — | — | — | +0.1% |
| FCF MarginFCF ÷ Revenue | — | — | — | -139.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | +27.5% |
| EPS Growth (YoY)Latest quarter vs prior year | +19.0% | +91.5% | +19.7% | +85.3% |
Valuation Metrics
Evenly matched — DBVT and AGEN each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $912M | $1712.35T | $5.5B | $132M |
| Enterprise ValueMkt cap + debt − cash | $878M | $1712.35T | $4.8B | $140M |
| Trailing P/EPrice ÷ TTM EPS | -5.99x | -0.76x | -9.97x | -1102.94x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 1.79x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | — | — | — | 1.16x |
| Price / BookPrice ÷ Book value/share | 2.01x | 0.66x | 5.83x | — |
| Price / FCFMarket cap ÷ FCF | — | — | — | — |
Profitability & Efficiency
Evenly matched — IMVT and AGEN each lead in 3 of 8 comparable metrics.
Profitability & Efficiency
ORIC delivers a -35.3% return on equity — every $100 of shareholder capital generates $-35 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DBVT's 0.13x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -35.3% | -130.2% | -47.1% | — |
| ROA (TTM)Return on assets | -33.3% | -89.0% | -44.1% | +0.1% |
| ROICReturn on invested capital | -39.9% | — | — | — |
| ROCEReturn on capital employed | -44.7% | -145.7% | -66.1% | — |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 2 | 6 |
| Debt / EquityFinancial leverage | 0.03x | 0.13x | 0.00x | — |
| Net DebtTotal debt minus cash | -$34M | -$172M | -$714M | $7M |
| Cash & Equiv.Liquid assets | $46M | $194M | $714M | $3M |
| Total DebtShort + long-term debt | $12M | $22M | $98,000 | $10M |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | — | 1.11x |
Total Returns (Dividends Reinvested)
Evenly matched — ORIC and IMVT each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $611 for AGEN. Over the past 12 months, DBVT leads with a +110.4% total return vs AGEN's +27.1%. The 3-year compound annual growth rate (CAGR) favors ORIC at 19.1% vs AGEN's -51.0% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | +7.8% | +4.9% | +5.1% | +16.1% |
| 1-Year ReturnPast 12 months | +87.4% | +110.4% | +96.1% | +27.1% |
| 3-Year ReturnCumulative with dividends | +68.8% | +19.7% | +40.9% | -88.2% |
| 5-Year ReturnCumulative with dividends | -63.1% | -69.1% | +62.4% | -93.9% |
| 10-Year ReturnCumulative with dividends | -65.8% | -87.0% | +173.6% | -94.3% |
| CAGR (3Y)Annualised 3-year return | +19.1% | +6.2% | +12.1% | -51.0% |
Risk & Volatility
Evenly matched — ORIC and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
ORIC is the less volatile stock with a 1.12 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs AGEN's 51.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.12x | 1.26x | 1.37x | 2.72x |
| 52-Week HighHighest price in past year | $14.93 | $26.18 | $30.09 | $7.34 |
| 52-Week LowLowest price in past year | $4.52 | $7.53 | $13.36 | $2.71 |
| % of 52W HighCurrent price vs 52-week peak | +59.0% | +76.3% | +90.5% | +51.1% |
| RSI (14)Momentum oscillator 0–100 | 39.7 | 48.1 | 60.2 | 48.8 |
| Avg Volume (50D)Average daily shares traded | 1.9M | 252K | 1.4M | 814K |
Analyst Outlook
AGEN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ORIC as "Buy", DBVT as "Buy", IMVT as "Buy", AGEN as "Buy". Consensus price targets imply 146.9% upside for ORIC (target: $22) vs 67.2% for IMVT (target: $46).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $21.75 | $46.33 | $45.50 | $7.33 |
| # AnalystsCovering analysts | 10 | 15 | 23 | 11 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.1% |
DBVT leads in 1 of 6 categories (Income & Cash Flow). AGEN leads in 1 (Analyst Outlook). 4 tied.
ORIC vs DBVT vs IMVT vs AGEN: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is ORIC or DBVT or IMVT or AGEN a better buy right now?
Analysts rate ORIC Pharmaceuticals, Inc.
(ORIC) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ORIC or DBVT or IMVT or AGEN?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -93. 9% for Agenus Inc. (AGEN). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus AGEN's -94. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ORIC or DBVT or IMVT or AGEN?
By beta (market sensitivity over 5 years), ORIC Pharmaceuticals, Inc.
(ORIC) is the lower-risk stock at 1. 12β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 144% more volatile than ORIC relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 13% for DBV Technologies S. A. — giving it more financial flexibility in a downturn.
04Which is growing faster — ORIC or DBVT or IMVT or AGEN?
On earnings-per-share growth, the picture is similar: Agenus Inc.
grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ORIC or DBVT or IMVT or AGEN?
Agenus Inc.
(AGEN) is the more profitable company, earning 0. 1% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ORIC leads at 0. 0% versus -18. 0% for AGEN. At the gross margin level — before operating expenses — AGEN leads at 90. 3%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ORIC or DBVT or IMVT or AGEN more undervalued right now?
Analyst consensus price targets imply the most upside for ORIC: 146.
9% to $21. 75.
07Which pays a better dividend — ORIC or DBVT or IMVT or AGEN?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is ORIC or DBVT or IMVT or AGEN better for a retirement portfolio?
For long-horizon retirement investors, ORIC Pharmaceuticals, Inc.
(ORIC) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 12)). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ORIC: -65. 8%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ORIC and DBVT and IMVT and AGEN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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