Drug Manufacturers - Specialty & Generic
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PRPH vs DBVT vs NVAX vs ALKS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
PRPH vs DBVT vs NVAX vs ALKS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Drug Manufacturers - Specialty & Generic | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $5M | $1712.35T | $1.50B | $5.90B |
| Revenue (TTM) | $1M | $0.00 | $596M | $1.56B |
| Net Income (TTM) | $-42M | $-168M | $-88M | $153M |
| Gross Margin | 191.4% | — | 84.6% | 65.4% |
| Operating Margin | -25.0% | — | -11.2% | 12.3% |
| Forward P/E | — | — | 3.6x | 24.8x |
| Total Debt | $25M | $22M | $249M | $70M |
| Cash & Equiv. | $678K | $194M | $241M | $1.12B |
PRPH vs DBVT vs NVAX vs ALKS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| ProPhase Labs, Inc. (PRPH) | 100 | 3.8 | -96.2% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Novavax, Inc. (NVAX) | 100 | 20.0 | -80.0% |
| Alkermes plc (ALKS) | 100 | 216.4 | +116.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: PRPH vs DBVT vs NVAX vs ALKS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
PRPH is the clearest fit if your priority is income & stability and long-term compounding.
- Dividend streak 1 yrs, beta 2.28
- 37.5% 10Y total return vs ALKS's -11.0%
DBVT is the clearest fit if your priority is momentum.
- +110.4% vs PRPH's -58.0%
NVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
- 64.7% revenue growth vs DBVT's -100.0%
- Lower P/E (3.6x vs 24.8x)
ALKS carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.
- Lower volatility, beta 1.06, Low D/E 3.8%, current ratio 3.55x
- Beta 1.06, current ratio 3.55x
- 9.8% margin vs PRPH's -38.7%
- Beta 1.06 vs PRPH's 2.28, lower leverage
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 64.7% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (3.6x vs 24.8x) | |
| Quality / Margins | 9.8% margin vs PRPH's -38.7% | |
| Stability / Safety | Beta 1.06 vs PRPH's 2.28, lower leverage | |
| Dividends | Tie | None of these 4 stocks pay a meaningful dividend |
| Momentum (1Y) | +110.4% vs PRPH's -58.0% | |
| Efficiency (ROA) | 5.4% ROA vs DBVT's -89.0% |
PRPH vs DBVT vs NVAX vs ALKS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
PRPH vs DBVT vs NVAX vs ALKS — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ALKS leads in 3 of 6 categories
PRPH leads 1 • NVAX leads 1 • DBVT leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
ALKS leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ALKS and DBVT operate at a comparable scale, with $1.6B and $0 in trailing revenue. ALKS is the more profitable business, keeping 9.8% of every revenue dollar as net income compared to PRPH's -38.7%. On growth, ALKS holds the edge at +28.2% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $1M | $0 | $596M | $1.6B |
| EBITDAEarnings before interest/tax | -$22M | -$112M | -$47M | $212M |
| Net IncomeAfter-tax profit | -$42M | -$168M | -$88M | $153M |
| Free Cash FlowCash after capex | -$23M | -$151M | -$96M | $392M |
| Gross MarginGross profit ÷ Revenue | +191.4% | — | +84.6% | +65.4% |
| Operating MarginEBIT ÷ Revenue | -25.0% | — | -11.2% | +12.3% |
| Net MarginNet income ÷ Revenue | -38.7% | — | -14.7% | +9.8% |
| FCF MarginFCF ÷ Revenue | -21.1% | — | -16.1% | +25.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | -71.9% | — | -79.1% | +28.2% |
| EPS Growth (YoY)Latest quarter vs prior year | +54.3% | +91.5% | -102.0% | -4.1% |
Valuation Metrics
PRPH leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
At 3.6x trailing earnings, NVAX trades at a 85% valuation discount to ALKS's 24.8x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than ALKS's 17.3x.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $5M | $1712.35T | $1.5B | $5.9B |
| Enterprise ValueMkt cap + debt − cash | $29M | $1712.35T | $1.5B | $4.9B |
| Trailing P/EPrice ÷ TTM EPS | -0.05x | -0.76x | 3.63x | 24.76x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | 2.56x | 17.25x |
| Price / SalesMarket cap ÷ Revenue | 0.74x | — | 1.34x | 4.00x |
| Price / BookPrice ÷ Book value/share | 0.31x | 0.66x | — | 3.28x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 12.28x |
Profitability & Efficiency
ALKS leads this category, winning 7 of 9 comparable metrics.
Profitability & Efficiency
ALKS delivers a 8.8% return on equity — every $100 of shareholder capital generates $9 in annual profit, vs $-6 for PRPH. ALKS carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to PRPH's 3.34x. On the Piotroski fundamental quality scale (0–9), ALKS scores 7/9 vs PRPH's 1/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -6.1% | -130.2% | — | +8.8% |
| ROA (TTM)Return on assets | -63.5% | -89.0% | -7.4% | +5.4% |
| ROICReturn on invested capital | -59.4% | — | — | +18.9% |
| ROCEReturn on capital employed | -75.6% | -145.7% | +100.4% | +14.2% |
| Piotroski ScoreFundamental quality 0–9 | 1 | 4 | 5 | 7 |
| Debt / EquityFinancial leverage | 3.34x | 0.13x | — | 0.04x |
| Net DebtTotal debt minus cash | $24M | -$172M | $8M | -$1.0B |
| Cash & Equiv.Liquid assets | $678,000 | $194M | $241M | $1.1B |
| Total DebtShort + long-term debt | $25M | $22M | $249M | $70M |
| Interest CoverageEBIT ÷ Interest expense | -7.96x | -189.82x | -5.10x | 32.30x |
Total Returns (Dividends Reinvested)
NVAX leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ALKS five years ago would be worth $16,091 today (with dividends reinvested), compared to $524 for NVAX. Over the past 12 months, DBVT leads with a +110.4% total return vs PRPH's -58.0%. The 3-year compound annual growth rate (CAGR) favors NVAX at 7.4% vs PRPH's -69.4% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -66.7% | +4.9% | +29.5% | +25.3% |
| 1-Year ReturnPast 12 months | -58.0% | +110.4% | +55.1% | +16.5% |
| 3-Year ReturnCumulative with dividends | -97.1% | +19.7% | +23.9% | +14.5% |
| 5-Year ReturnCumulative with dividends | -63.2% | -69.1% | -94.8% | +60.9% |
| 10-Year ReturnCumulative with dividends | +37.5% | -87.0% | -90.4% | -11.0% |
| CAGR (3Y)Annualised 3-year return | -69.4% | +6.2% | +7.4% | +4.6% |
Risk & Volatility
ALKS leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
ALKS is the less volatile stock with a 1.06 beta — it tends to amplify market swings less than PRPH's 2.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALKS currently trades 96.7% from its 52-week high vs PRPH's 6.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.28x | 1.26x | 2.11x | 1.06x |
| 52-Week HighHighest price in past year | $1.84 | $26.18 | $11.97 | $36.60 |
| 52-Week LowLowest price in past year | $0.07 | $7.53 | $5.80 | $25.17 |
| % of 52W HighCurrent price vs 52-week peak | +6.5% | +76.3% | +77.1% | +96.7% |
| RSI (14)Momentum oscillator 0–100 | 56.8 | 48.1 | 64.4 | 60.2 |
| Avg Volume (50D)Average daily shares traded | 105K | 252K | 4.4M | 2.3M |
Analyst Outlook
Evenly matched — PRPH and NVAX each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: DBVT as "Buy", NVAX as "Buy", ALKS as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 24.3% for ALKS (target: $44).
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $46.33 | $18.00 | $44.00 |
| # AnalystsCovering analysts | — | 15 | 23 | 28 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | 0 | 1 | 0 |
| Dividend / ShareAnnual DPS | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.3% | +0.5% |
ALKS leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). PRPH leads in 1 (Valuation Metrics). 1 tied.
PRPH vs DBVT vs NVAX vs ALKS: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is PRPH or DBVT or NVAX or ALKS a better buy right now?
For growth investors, Novavax, Inc.
(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus -84. 7% for ProPhase Labs, Inc. (PRPH). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate DBV Technologies S. A. (DBVT) a "Buy" — based on 15 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — PRPH or DBVT or NVAX or ALKS?
On trailing P/E, Novavax, Inc.
(NVAX) is the cheapest at 3. 6x versus Alkermes plc at 24. 8x.
03Which is the better long-term investment — PRPH or DBVT or NVAX or ALKS?
Over the past 5 years, Alkermes plc (ALKS) delivered a total return of +60.
9%, compared to -94. 8% for Novavax, Inc. (NVAX). Over 10 years, the gap is even starker: PRPH returned +37. 5% versus NVAX's -90. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — PRPH or DBVT or NVAX or ALKS?
By beta (market sensitivity over 5 years), Alkermes plc (ALKS) is the lower-risk stock at 1.
06β versus ProPhase Labs, Inc. 's 2. 28β — meaning PRPH is approximately 115% more volatile than ALKS relative to the S&P 500. On balance sheet safety, Alkermes plc (ALKS) carries a lower debt/equity ratio of 4% versus 3% for ProPhase Labs, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — PRPH or DBVT or NVAX or ALKS?
By revenue growth (latest reported year), Novavax, Inc.
(NVAX) is pulling ahead at 64. 7% versus -84. 7% for ProPhase Labs, Inc. (PRPH). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALKS leads at 9. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — PRPH or DBVT or NVAX or ALKS?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus -788. 2% for ProPhase Labs, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -570. 6% for PRPH. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Which pays a better dividend — PRPH or DBVT or NVAX or ALKS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is PRPH or DBVT or NVAX or ALKS better for a retirement portfolio?
For long-horizon retirement investors, Alkermes plc (ALKS) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
06)). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ALKS: -11. 0%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between PRPH and DBVT and NVAX and ALKS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: PRPH is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; NVAX is a small-cap high-growth stock; ALKS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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