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Stock Comparison

SYBX vs IMVT vs ACMR

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
SYBX
Synlogic, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7M
5Y Perf.-98.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$5.53B
5Y Perf.+6.1%
ACMR
ACM Research, Inc.

Semiconductors

TechnologyNASDAQ • US
Market Cap$3.92B
5Y Perf.+197.0%

SYBX vs IMVT vs ACMR — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
SYBX logoSYBX
IMVT logoIMVT
ACMR logoACMR
IndustryBiotechnologyBiotechnologySemiconductors
Market Cap$7M$5.53B$3.92B
Revenue (TTM)$0.00$0.00$901M
Net Income (TTM)$-1M$-464M$94M
Gross Margin44.4%
Operating Margin12.1%
Forward P/E29.7x
Total Debt$0.00$98K$303M
Cash & Equiv.$15M$714M$766M

SYBX vs IMVT vs ACMRLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

SYBX
IMVT
ACMR
StockMay 20May 26Return
Synlogic, Inc. (SYBX)1001.6-98.4%
Immunovant, Inc. (IMVT)100106.1+6.1%
ACM Research, Inc. (ACMR)100297.0+197.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: SYBX vs IMVT vs ACMR

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ACMR leads in 5 of 6 categories, making it the strongest pick for growth and revenue expansion and profitability and margin quality. Immunovant, Inc. is the stronger pick specifically for capital preservation and lower volatility. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
SYBX
Synlogic, Inc.
The Secondary Option

SYBX plays a supporting role in this comparison — it may shine differently against other peers.

Best for: healthcare exposure
IMVT
Immunovant, Inc.
The Income Pick

IMVT is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • beta 1.37
  • Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
  • Beta 1.37, current ratio 11.16x
Best for: income & stability and sleep-well-at-night
ACMR
ACM Research, Inc.
The Growth Play

ACMR carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 15.2%, EPS growth -10.5%, 3Y rev CAGR 32.3%
  • 30.7% 10Y total return vs IMVT's 173.6%
  • 15.2% revenue growth vs SYBX's -100.0%
Best for: growth exposure and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthACMR logoACMR15.2% revenue growth vs SYBX's -100.0%
Quality / MarginsACMR logoACMR10.4% margin vs IMVT's 3.2%
Stability / SafetyIMVT logoIMVTBeta 1.37 vs ACMR's 3.24, lower leverage
DividendsACMR logoACMR0.2% yield; 3-year raise streak; the other 2 pay no meaningful dividend
Momentum (1Y)ACMR logoACMR+195.6% vs SYBX's -46.4%
Efficiency (ROA)ACMR logoACMR3.9% ROA vs IMVT's -44.1%

SYBX vs IMVT vs ACMR — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

SYBXSynlogic, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

ACMRACM Research, Inc.
FY 2025
Total Single Wafer and Semi-Critical Cleaning Equipment
69.5%$626M
ECP Front End And Packaging Furnace And Other Technologies
22.1%$200M
Advanced Packaging (exclude ECP), Services & Spares
8.4%$76M

SYBX vs IMVT vs ACMR — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLACMRLAGGINGIMVT

Income & Cash Flow (Last 12 Months)

SYBX leads this category, winning 1 of 1 comparable metric.

ACMR and IMVT operate at a comparable scale, with $901M and $0 in trailing revenue.

MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
RevenueTrailing 12 months$0$0$901M
EBITDAEarnings before interest/tax-$4M-$487M$126M
Net IncomeAfter-tax profit-$1M-$464M$94M
Free Cash FlowCash after capex-$4M-$423M-$69M
Gross MarginGross profit ÷ Revenue+44.4%
Operating MarginEBIT ÷ Revenue+12.1%
Net MarginNet income ÷ Revenue+10.4%
FCF MarginFCF ÷ Revenue-7.6%
Rev. Growth (YoY)Latest quarter vs prior year+9.4%
EPS Growth (YoY)Latest quarter vs prior year+3.2%+19.7%-76.1%
SYBX leads this category, winning 1 of 1 comparable metric.

Valuation Metrics

Evenly matched — SYBX and IMVT each lead in 1 of 2 comparable metrics.
MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
Market CapShares × price$7M$5.5B$3.9B
Enterprise ValueMkt cap + debt − cash-$8M$4.8B$3.5B
Trailing P/EPrice ÷ TTM EPS-7.50x-9.97x43.21x
Forward P/EPrice ÷ next-FY EPS est.29.68x
PEG RatioP/E ÷ EPS growth rate1.22x
EV / EBITDAEnterprise value multiple27.49x
Price / SalesMarket cap ÷ Revenue4.35x
Price / BookPrice ÷ Book value/share0.62x5.83x2.06x
Price / FCFMarket cap ÷ FCF
Evenly matched — SYBX and IMVT each lead in 1 of 2 comparable metrics.

Profitability & Efficiency

ACMR leads this category, winning 3 of 6 comparable metrics.

ACMR delivers a 6.1% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ACMR's 0.16x.

MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
ROE (TTM)Return on equity-8.4%-47.1%+6.1%
ROA (TTM)Return on assets-6.0%-44.1%+3.9%
ROICReturn on invested capital+7.0%
ROCEReturn on capital employed-32.6%-66.1%+6.6%
Piotroski ScoreFundamental quality 0–9222
Debt / EquityFinancial leverage0.00x0.16x
Net DebtTotal debt minus cash-$15M-$714M-$463M
Cash & Equiv.Liquid assets$15M$714M$766M
Total DebtShort + long-term debt$0$98,000$303M
Interest CoverageEBIT ÷ Interest expense20.44x
ACMR leads this category, winning 3 of 6 comparable metrics.

Total Returns (Dividends Reinvested)

ACMR leads this category, winning 6 of 6 comparable metrics.

A $10,000 investment in ACMR five years ago would be worth $23,344 today (with dividends reinvested), compared to $127 for SYBX. Over the past 12 months, ACMR leads with a +195.6% total return vs SYBX's -46.4%. The 3-year compound annual growth rate (CAGR) favors ACMR at 80.5% vs SYBX's -58.5% — a key indicator of consistent wealth creation.

MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
YTD ReturnYear-to-date-48.7%+5.1%+31.9%
1-Year ReturnPast 12 months-46.4%+96.1%+195.6%
3-Year ReturnCumulative with dividends-92.9%+40.9%+487.9%
5-Year ReturnCumulative with dividends-98.7%+62.4%+133.4%
10-Year ReturnCumulative with dividends-98.0%+173.6%+3065.8%
CAGR (3Y)Annualised 3-year return-58.5%+12.1%+80.5%
ACMR leads this category, winning 6 of 6 comparable metrics.

Risk & Volatility

IMVT leads this category, winning 2 of 2 comparable metrics.

IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than ACMR's 3.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs SYBX's 30.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
Beta (5Y)Sensitivity to S&P 5001.60x1.37x3.24x
52-Week HighHighest price in past year$1.96$30.09$71.65
52-Week LowLowest price in past year$0.54$13.36$19.26
% of 52W HighCurrent price vs 52-week peak+30.6%+90.5%+82.6%
RSI (14)Momentum oscillator 0–10041.660.260.7
Avg Volume (50D)Average daily shares traded11K1.4M1.2M
IMVT leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: IMVT as "Buy", ACMR as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs -32.4% for ACMR (target: $40). ACMR is the only dividend payer here at 0.19% yield — a key consideration for income-focused portfolios.

MetricSYBX logoSYBXSynlogic, Inc.IMVT logoIMVTImmunovant, Inc.ACMR logoACMRACM Research, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$45.50$40.00
# AnalystsCovering analysts2310
Dividend YieldAnnual dividend ÷ price+0.2%
Dividend StreakConsecutive years of raises3
Dividend / ShareAnnual DPS$0.11
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%
Insufficient data to determine a leader in this category.
Key Takeaway

ACMR leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). SYBX leads in 1 (Income & Cash Flow). 1 tied.

Best OverallACM Research, Inc. (ACMR)Leads 2 of 6 categories
Loading custom metrics...

SYBX vs IMVT vs ACMR: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is SYBX or IMVT or ACMR a better buy right now?

For growth investors, ACM Research, Inc.

(ACMR) is the stronger pick with 15. 2% revenue growth year-over-year, versus -100. 0% for Synlogic, Inc. (SYBX). ACM Research, Inc. (ACMR) offers the better valuation at 43. 2x trailing P/E (29. 7x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — SYBX or IMVT or ACMR?

Over the past 5 years, ACM Research, Inc.

(ACMR) delivered a total return of +133. 4%, compared to -98. 7% for Synlogic, Inc. (SYBX). Over 10 years, the gap is even starker: ACMR returned +30. 7% versus SYBX's -98. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — SYBX or IMVT or ACMR?

By beta (market sensitivity over 5 years), Immunovant, Inc.

(IMVT) is the lower-risk stock at 1. 37β versus ACM Research, Inc. 's 3. 24β — meaning ACMR is approximately 136% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 16% for ACM Research, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — SYBX or IMVT or ACMR?

By revenue growth (latest reported year), ACM Research, Inc.

(ACMR) is pulling ahead at 15. 2% versus -100. 0% for Synlogic, Inc. (SYBX). On earnings-per-share growth, the picture is similar: Synlogic, Inc. grew EPS 95. 8% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — SYBX or IMVT or ACMR?

ACM Research, Inc.

(ACMR) is the more profitable company, earning 10. 4% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 10. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ACMR leads at 12. 1% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — ACMR leads at 44. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is SYBX or IMVT or ACMR more undervalued right now?

Analyst consensus price targets imply the most upside for IMVT: 67.

2% to $45. 50.

07

Which pays a better dividend — SYBX or IMVT or ACMR?

In this comparison, ACMR (0.

2% yield) pays a dividend. SYBX, IMVT do not pay a meaningful dividend and should not be held primarily for income.

08

Is SYBX or IMVT or ACMR better for a retirement portfolio?

For long-horizon retirement investors, Immunovant, Inc.

(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). ACM Research, Inc. (ACMR) carries a higher beta of 3. 24 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, ACMR: +30. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between SYBX and IMVT and ACMR?

These companies operate in different sectors (SYBX (Healthcare) and IMVT (Healthcare) and ACMR (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: SYBX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ACMR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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SYBX

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