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SYBX vs IMVT vs ACMR
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Semiconductors
SYBX vs IMVT vs ACMR — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Semiconductors |
| Market Cap | $7M | $5.53B | $3.92B |
| Revenue (TTM) | $0.00 | $0.00 | $901M |
| Net Income (TTM) | $-1M | $-464M | $94M |
| Gross Margin | — | — | 44.4% |
| Operating Margin | — | — | 12.1% |
| Forward P/E | — | — | 29.7x |
| Total Debt | $0.00 | $98K | $303M |
| Cash & Equiv. | $15M | $714M | $766M |
SYBX vs IMVT vs ACMR — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Synlogic, Inc. (SYBX) | 100 | 1.6 | -98.4% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| ACM Research, Inc. (ACMR) | 100 | 297.0 | +197.0% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SYBX vs IMVT vs ACMR
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SYBX plays a supporting role in this comparison — it may shine differently against other peers.
IMVT is the clearest fit if your priority is income & stability and sleep-well-at-night.
- beta 1.37
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
ACMR carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.
- Rev growth 15.2%, EPS growth -10.5%, 3Y rev CAGR 32.3%
- 30.7% 10Y total return vs IMVT's 173.6%
- 15.2% revenue growth vs SYBX's -100.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 15.2% revenue growth vs SYBX's -100.0% | |
| Quality / Margins | 10.4% margin vs IMVT's 3.2% | |
| Stability / Safety | Beta 1.37 vs ACMR's 3.24, lower leverage | |
| Dividends | 0.2% yield; 3-year raise streak; the other 2 pay no meaningful dividend | |
| Momentum (1Y) | +195.6% vs SYBX's -46.4% | |
| Efficiency (ROA) | 3.9% ROA vs IMVT's -44.1% |
SYBX vs IMVT vs ACMR — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
SYBX vs IMVT vs ACMR — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
ACMR leads in 2 of 6 categories
SYBX leads 1 • IMVT leads 1 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
SYBX leads this category, winning 1 of 1 comparable metric.
Income & Cash Flow (Last 12 Months)
ACMR and IMVT operate at a comparable scale, with $901M and $0 in trailing revenue.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $901M |
| EBITDAEarnings before interest/tax | -$4M | -$487M | $126M |
| Net IncomeAfter-tax profit | -$1M | -$464M | $94M |
| Free Cash FlowCash after capex | -$4M | -$423M | -$69M |
| Gross MarginGross profit ÷ Revenue | — | — | +44.4% |
| Operating MarginEBIT ÷ Revenue | — | — | +12.1% |
| Net MarginNet income ÷ Revenue | — | — | +10.4% |
| FCF MarginFCF ÷ Revenue | — | — | -7.6% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +9.4% |
| EPS Growth (YoY)Latest quarter vs prior year | +3.2% | +19.7% | -76.1% |
Valuation Metrics
Evenly matched — SYBX and IMVT each lead in 1 of 2 comparable metrics.
Valuation Metrics
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $7M | $5.5B | $3.9B |
| Enterprise ValueMkt cap + debt − cash | -$8M | $4.8B | $3.5B |
| Trailing P/EPrice ÷ TTM EPS | -7.50x | -9.97x | 43.21x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 29.68x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 1.22x |
| EV / EBITDAEnterprise value multiple | — | — | 27.49x |
| Price / SalesMarket cap ÷ Revenue | — | — | 4.35x |
| Price / BookPrice ÷ Book value/share | 0.62x | 5.83x | 2.06x |
| Price / FCFMarket cap ÷ FCF | — | — | — |
Profitability & Efficiency
ACMR leads this category, winning 3 of 6 comparable metrics.
Profitability & Efficiency
ACMR delivers a 6.1% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-47 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ACMR's 0.16x.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -8.4% | -47.1% | +6.1% |
| ROA (TTM)Return on assets | -6.0% | -44.1% | +3.9% |
| ROICReturn on invested capital | — | — | +7.0% |
| ROCEReturn on capital employed | -32.6% | -66.1% | +6.6% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 | 2 |
| Debt / EquityFinancial leverage | — | 0.00x | 0.16x |
| Net DebtTotal debt minus cash | -$15M | -$714M | -$463M |
| Cash & Equiv.Liquid assets | $15M | $714M | $766M |
| Total DebtShort + long-term debt | $0 | $98,000 | $303M |
| Interest CoverageEBIT ÷ Interest expense | — | — | 20.44x |
Total Returns (Dividends Reinvested)
ACMR leads this category, winning 6 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in ACMR five years ago would be worth $23,344 today (with dividends reinvested), compared to $127 for SYBX. Over the past 12 months, ACMR leads with a +195.6% total return vs SYBX's -46.4%. The 3-year compound annual growth rate (CAGR) favors ACMR at 80.5% vs SYBX's -58.5% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | -48.7% | +5.1% | +31.9% |
| 1-Year ReturnPast 12 months | -46.4% | +96.1% | +195.6% |
| 3-Year ReturnCumulative with dividends | -92.9% | +40.9% | +487.9% |
| 5-Year ReturnCumulative with dividends | -98.7% | +62.4% | +133.4% |
| 10-Year ReturnCumulative with dividends | -98.0% | +173.6% | +3065.8% |
| CAGR (3Y)Annualised 3-year return | -58.5% | +12.1% | +80.5% |
Risk & Volatility
IMVT leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
IMVT is the less volatile stock with a 1.37 beta — it tends to amplify market swings less than ACMR's 3.24 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs SYBX's 30.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.60x | 1.37x | 3.24x |
| 52-Week HighHighest price in past year | $1.96 | $30.09 | $71.65 |
| 52-Week LowLowest price in past year | $0.54 | $13.36 | $19.26 |
| % of 52W HighCurrent price vs 52-week peak | +30.6% | +90.5% | +82.6% |
| RSI (14)Momentum oscillator 0–100 | 41.6 | 60.2 | 60.7 |
| Avg Volume (50D)Average daily shares traded | 11K | 1.4M | 1.2M |
Analyst Outlook
Insufficient data to determine a leader in this category.
Analyst Outlook
Analyst consensus: IMVT as "Buy", ACMR as "Buy". Consensus price targets imply 67.2% upside for IMVT (target: $46) vs -32.4% for ACMR (target: $40). ACMR is the only dividend payer here at 0.19% yield — a key consideration for income-focused portfolios.
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy |
| Price TargetConsensus 12-month target | — | $45.50 | $40.00 |
| # AnalystsCovering analysts | — | 23 | 10 |
| Dividend YieldAnnual dividend ÷ price | — | — | +0.2% |
| Dividend StreakConsecutive years of raises | — | — | 3 |
| Dividend / ShareAnnual DPS | — | — | $0.11 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +0.2% |
ACMR leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). SYBX leads in 1 (Income & Cash Flow). 1 tied.
SYBX vs IMVT vs ACMR: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is SYBX or IMVT or ACMR a better buy right now?
For growth investors, ACM Research, Inc.
(ACMR) is the stronger pick with 15. 2% revenue growth year-over-year, versus -100. 0% for Synlogic, Inc. (SYBX). ACM Research, Inc. (ACMR) offers the better valuation at 43. 2x trailing P/E (29. 7x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — SYBX or IMVT or ACMR?
Over the past 5 years, ACM Research, Inc.
(ACMR) delivered a total return of +133. 4%, compared to -98. 7% for Synlogic, Inc. (SYBX). Over 10 years, the gap is even starker: ACMR returned +30. 7% versus SYBX's -98. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — SYBX or IMVT or ACMR?
By beta (market sensitivity over 5 years), Immunovant, Inc.
(IMVT) is the lower-risk stock at 1. 37β versus ACM Research, Inc. 's 3. 24β — meaning ACMR is approximately 136% more volatile than IMVT relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 16% for ACM Research, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — SYBX or IMVT or ACMR?
By revenue growth (latest reported year), ACM Research, Inc.
(ACMR) is pulling ahead at 15. 2% versus -100. 0% for Synlogic, Inc. (SYBX). On earnings-per-share growth, the picture is similar: Synlogic, Inc. grew EPS 95. 8% year-over-year, compared to -45. 2% for Immunovant, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — SYBX or IMVT or ACMR?
ACM Research, Inc.
(ACMR) is the more profitable company, earning 10. 4% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 10. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: ACMR leads at 12. 1% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — ACMR leads at 44. 4%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is SYBX or IMVT or ACMR more undervalued right now?
Analyst consensus price targets imply the most upside for IMVT: 67.
2% to $45. 50.
07Which pays a better dividend — SYBX or IMVT or ACMR?
In this comparison, ACMR (0.
2% yield) pays a dividend. SYBX, IMVT do not pay a meaningful dividend and should not be held primarily for income.
08Is SYBX or IMVT or ACMR better for a retirement portfolio?
For long-horizon retirement investors, Immunovant, Inc.
(IMVT) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (+173. 6% 10Y return). ACM Research, Inc. (ACMR) carries a higher beta of 3. 24 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (IMVT: +173. 6%, ACMR: +30. 7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between SYBX and IMVT and ACMR?
These companies operate in different sectors (SYBX (Healthcare) and IMVT (Healthcare) and ACMR (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: SYBX is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ACMR is a small-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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