Biotechnology
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5 / 10Stock Comparison
YDESW vs OCGN vs BNTX vs NVAX vs MRNA
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
YDESW vs OCGN vs BNTX vs NVAX vs MRNA — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | — | $498M | $23.69B | $1.58B | $21.13B |
| Revenue (TTM) | $510K | $4M | $2.86B | $596M | $2.23B |
| Net Income (TTM) | $-1M | $-68M | $-1.13B | $-88M | $-3.19B |
| Gross Margin | 30.4% | 100.0% | 77.7% | 84.6% | -13.9% |
| Operating Margin | -286.5% | -14.3% | -45.9% | -11.2% | -153.3% |
| Forward P/E | — | — | — | 3.8x | — |
| Total Debt | $23K | $33M | $267M | $249M | $1.92B |
| Cash & Equiv. | $3M | $19M | $7.67B | $241M | $2.60B |
YDESW vs OCGN vs BNTX vs NVAX vs MRNA — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Ocugen, Inc. (OCGN) | 100 | 474.2 | +374.2% |
| BioNTech SE (BNTX) | 100 | 189.1 | +89.1% |
| Novavax, Inc. (NVAX) | 100 | 20.9 | -79.1% |
| Moderna, Inc. (MRNA) | 100 | 86.6 | -13.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: YDESW vs OCGN vs BNTX vs NVAX vs MRNA
Each card shows where this stock fits in a portfolio — not just who wins on paper.
YDESW lags the leaders in this set but could rank higher in a more targeted comparison.
OCGN ranks third and is worth considering specifically for momentum.
- +110.0% vs YDESW's -9.2%
BNTX carries the broadest edge in this set and is the clearest fit for income & stability and long-term compounding.
- Dividend streak 1 yrs, beta 1.05
- 5.7% 10Y total return vs YDESW's -9.2%
- Lower volatility, beta 1.05, Low D/E 1.4%, current ratio 7.54x
- Beta 1.05, current ratio 7.54x
NVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
- 64.7% revenue growth vs MRNA's -39.2%
- -14.7% margin vs OCGN's -15.4%
Among these 5 stocks, MRNA doesn't own a clear edge in any measured category.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 64.7% revenue growth vs MRNA's -39.2% | |
| Quality / Margins | -14.7% margin vs OCGN's -15.4% | |
| Stability / Safety | Beta 1.05 vs YDESW's 2.23 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +110.0% vs YDESW's -9.2% | |
| Efficiency (ROA) | -5.3% ROA vs OCGN's -123.4%, ROIC -4.3% vs -15.7% |
YDESW vs OCGN vs BNTX vs NVAX vs MRNA — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
YDESW vs OCGN vs BNTX vs NVAX vs MRNA — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
BNTX leads in 2 of 6 categories
OCGN leads 1 • YDESW leads 0 • NVAX leads 0 • MRNA leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — OCGN and NVAX each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
BNTX is the larger business by revenue, generating $2.9B annually — 5606.6x YDESW's $510,360. Profitability is closely matched — net margins range from -14.7% (NVAX) to -15.4% (OCGN). On growth, MRNA holds the edge at +2.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $510,360 | $4M | $2.9B | $596M | $2.2B |
| EBITDAEarnings before interest/tax | — | -$61M | -$931M | -$47M | -$3.2B |
| Net IncomeAfter-tax profit | — | -$68M | -$1.1B | -$88M | -$3.2B |
| Free Cash FlowCash after capex | — | -$57M | $277M | -$97M | -$1.6B |
| Gross MarginGross profit ÷ Revenue | +30.4% | +100.0% | +77.7% | +84.6% | -13.9% |
| Operating MarginEBIT ÷ Revenue | -2.9% | -14.3% | -45.9% | -11.2% | -153.3% |
| Net MarginNet income ÷ Revenue | -2.8% | -15.4% | -39.6% | -14.7% | -143.6% |
| FCF MarginFCF ÷ Revenue | -9.3% | -13.0% | +9.7% | -16.3% | -71.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | -125.3% | -24.5% | -79.1% | +2.6% |
| EPS Growth (YoY)Latest quarter vs prior year | — | -18.9% | -2.1% | -102.0% | -34.9% |
Valuation Metrics
BNTX leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | — | $498M | $23.7B | $1.6B | $21.1B |
| Enterprise ValueMkt cap + debt − cash | — | $512M | $15.0B | $1.6B | $20.4B |
| Trailing P/EPrice ÷ TTM EPS | — | -6.39x | -17.67x | 3.79x | -7.34x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | 2.69x | — |
| Price / SalesMarket cap ÷ Revenue | — | 112.76x | 7.31x | 1.41x | 10.87x |
| Price / BookPrice ÷ Book value/share | — | — | 1.00x | — | 2.40x |
| Price / FCFMarket cap ÷ FCF | — | — | 74.67x | — | — |
Profitability & Efficiency
BNTX leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
BNTX delivers a -6.0% return on equity — every $100 of shareholder capital generates $-6 in annual profit, vs $-26 for OCGN. YDESW carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to MRNA's 0.22x. On the Piotroski fundamental quality scale (0–9), NVAX scores 5/9 vs OCGN's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -42.7% | -26.3% | -6.0% | — | -36.7% |
| ROA (TTM)Return on assets | -39.3% | -123.4% | -5.3% | -7.4% | -26.6% |
| ROICReturn on invested capital | -63.3% | -15.7% | -4.3% | — | -26.1% |
| ROCEReturn on capital employed | -44.1% | -154.7% | -3.1% | +100.4% | -27.6% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 2 | 4 | 5 | 3 |
| Debt / EquityFinancial leverage | 0.00x | — | 0.01x | — | 0.22x |
| Net DebtTotal debt minus cash | -$3M | $15M | -$7.4B | $8M | -$679M |
| Cash & Equiv.Liquid assets | $3M | $19M | $7.7B | $241M | $2.6B |
| Total DebtShort + long-term debt | $22,555 | $33M | $267M | $249M | $1.9B |
| Interest CoverageEBIT ÷ Interest expense | -1893.69x | -13.63x | -62.15x | -6.40x | -1803.00x |
Total Returns (Dividends Reinvested)
OCGN leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in YDESW five years ago would be worth $9,083 today (with dividends reinvested), compared to $753 for NVAX. Over the past 12 months, OCGN leads with a +110.0% total return vs YDESW's -9.2%. The 3-year compound annual growth rate (CAGR) favors OCGN at 29.6% vs MRNA's -25.6% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -50.0% | +6.5% | -3.1% | +34.9% | +72.6% |
| 1-Year ReturnPast 12 months | -9.2% | +110.0% | -3.7% | +51.7% | +107.3% |
| 3-Year ReturnCumulative with dividends | -9.2% | +117.5% | -11.0% | +13.8% | -58.8% |
| 5-Year ReturnCumulative with dividends | -9.2% | -82.9% | -48.5% | -92.5% | -65.1% |
| 10-Year ReturnCumulative with dividends | -9.2% | -98.6% | +572.5% | -88.9% | +186.4% |
| CAGR (3Y)Annualised 3-year return | -3.2% | +29.6% | -3.8% | +4.4% | -25.6% |
Risk & Volatility
Evenly matched — BNTX and MRNA each lead in 1 of 2 comparable metrics.
Risk & Volatility
BNTX is the less volatile stock with a 1.05 beta — it tends to amplify market swings less than YDESW's 2.23 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. MRNA currently trades 89.5% from its 52-week high vs YDESW's 17.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.23x | 1.47x | 1.05x | 2.22x | 1.81x |
| 52-Week HighHighest price in past year | $2.85 | $2.73 | $124.00 | $11.97 | $59.55 |
| 52-Week LowLowest price in past year | $0.32 | $0.64 | $79.52 | $5.87 | $22.28 |
| % of 52W HighCurrent price vs 52-week peak | +17.4% | +53.9% | +75.5% | +80.4% | +89.5% |
| RSI (14)Momentum oscillator 0–100 | 48.2 | 38.0 | 41.2 | 60.4 | 56.5 |
| Avg Volume (50D)Average daily shares traded | 10K | 9.4M | 1.2M | 4.2M | 7.5M |
Analyst Outlook
Evenly matched — BNTX and NVAX each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: OCGN as "Buy", BNTX as "Buy", NVAX as "Buy", MRNA as "Hold". Consensus price targets imply 240.1% upside for OCGN (target: $5) vs -26.8% for MRNA (target: $39).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | — | Buy | Buy | Buy | Hold |
| Price TargetConsensus 12-month target | — | $5.00 | $139.44 | $18.00 | $39.00 |
| # AnalystsCovering analysts | — | 5 | 24 | 23 | 27 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | — | 1 | 1 | 0 |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | — | 0.0% | 0.0% | +0.3% | 0.0% |
BNTX leads in 2 of 6 categories (Valuation Metrics, Profitability & Efficiency). OCGN leads in 1 (Total Returns). 3 tied.
YDESW vs OCGN vs BNTX vs NVAX vs MRNA: Key Questions Answered
8 questions · data-driven answers · updated daily
01Is YDESW or OCGN or BNTX or NVAX or MRNA a better buy right now?
For growth investors, Novavax, Inc.
(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus -39. 2% for Moderna, Inc. (MRNA). Novavax, Inc. (NVAX) offers the better valuation at 3. 8x trailing P/E, making it the more compelling value choice. Analysts rate Ocugen, Inc. (OCGN) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — YDESW or OCGN or BNTX or NVAX or MRNA?
Over the past 5 years, YD Bio Limited Warrants (YDESW) delivered a total return of -9.
2%, compared to -92. 5% for Novavax, Inc. (NVAX). Over 10 years, the gap is even starker: BNTX returned +572. 5% versus OCGN's -98. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — YDESW or OCGN or BNTX or NVAX or MRNA?
By beta (market sensitivity over 5 years), BioNTech SE (BNTX) is the lower-risk stock at 1.
05β versus YD Bio Limited Warrants's 2. 23β — meaning YDESW is approximately 112% more volatile than BNTX relative to the S&P 500. On balance sheet safety, YD Bio Limited Warrants (YDESW) carries a lower debt/equity ratio of 0% versus 22% for Moderna, Inc. — giving it more financial flexibility in a downturn.
04Which is growing faster — YDESW or OCGN or BNTX or NVAX or MRNA?
By revenue growth (latest reported year), Novavax, Inc.
(NVAX) is pulling ahead at 64. 7% versus -39. 2% for Moderna, Inc. (MRNA). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -62. 8% for BioNTech SE. Over a 3-year CAGR, OCGN leads at 21. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — YDESW or OCGN or BNTX or NVAX or MRNA?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus -1537. 4% for Ocugen, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -1425. 7% for OCGN. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Which pays a better dividend — YDESW or OCGN or BNTX or NVAX or MRNA?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
07Is YDESW or OCGN or BNTX or NVAX or MRNA better for a retirement portfolio?
For long-horizon retirement investors, BioNTech SE (BNTX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
05), +572. 5% 10Y return). Novavax, Inc. (NVAX) carries a higher beta of 2. 22 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BNTX: +572. 5%, NVAX: -88. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
08What are the main differences between YDESW and OCGN and BNTX and NVAX and MRNA?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: YDESW is a small-cap high-growth stock; OCGN is a small-cap quality compounder stock; BNTX is a mid-cap quality compounder stock; NVAX is a small-cap high-growth stock; MRNA is a mid-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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