Exelixis, Inc. (EXEL) Earnings History
Annual and quarterly earnings data from 1999 to 2025
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EPS Growth Rates (CAGR)
Compound annual growth rate of diluted earnings per share
CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.
Profitability Analysis
Margin trends over time
| Year | Gross Margin | Operating Margin | Net Margin |
|---|---|---|---|
| 2025 | - | 37.6% | 33.7% |
| 2024 | 96.5% | 27.9% | 24.0% |
| 2023 | 96.0% | 9.3% | 11.4% |
| 2022 | 96.4% | 12.5% | 11.3% |
| 2021 | 96.3% | 20.0% | 16.1% |
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Exelixis, Inc. (EXEL) Earnings Overview
As of February 28, 2026, Exelixis, Inc. (EXEL) reported trailing twelve-month net income of $678M, reflecting +0.6% year-over-year growth. The company earned $2.43 per diluted share over the past four quarters, with a net profit margin of 0.3%.
Looking at the long-term picture, EXEL's 5-year EPS compound annual growth rate (CAGR) stands at +51.4%, indicating exceptional earnings growth. The company achieved its highest annual net income of $783M in fiscal 2025, representing a new all-time high.
Exelixis, Inc. maintains positive profitability with, operating margin of 0.4%, and net margin of 0.3%. The company continues to generate positive earnings from operations. View revenue history →
Compared to industry peers including RVMD (-$1.13B net income), INCY ($1.29B net income, 0.3% margin), GMAB ($6.57B net income, 0.4% margin), EXEL has comparable earnings metrics. Compare EXEL vs RVMD →
Peer Comparison
Earnings metrics vs industry competitors
Historical Data
27 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $783M | +50.1% | $872M | $2.78 | 33.7% | 37.6% |
| 2024 | $521M | +150.9% | $605M | $1.76 | 24.0% | 27.9% |
| 2023 | $208M | +14.0% | $171M | $0.65 | 11.4% | 9.3% |
| 2022 | $182M | -21.1% | $201M | $0.56 | 11.3% | 12.5% |
| 2021 | $231M | +106.7% | $287M | $0.72 | 16.1% | 20.0% |
| 2020 | $112M | -65.2% | $110M | $0.35 | 11.3% | 11.1% |
| 2019 | $321M | -53.5% | $369M | $1.02 | 33.2% | 38.2% |
| 2018 | $690M | +347.4% | $439M | $2.21 | 80.8% | 51.4% |
| 2017 | $154M | +319.6% | $166M | $0.49 | 34.1% | 36.7% |
| 2016 | -$70M | +58.6% | -$28M | $-0.28 | -36.7% | -14.7% |
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Start ComparisonFrequently Asked Questions
Is EXEL growing earnings?
EXEL EPS of $2.43 reflects slowing growth at +0.6%, below the 5-year CAGR of +51.4%. TTM net income is $678M. Expansion rate has moderated.
What are EXEL's profit margins?
Exelixis, Inc. net margin is +0.3%, with operating margin at +0.4%. Below-average margins reflect competitive or cost pressures.
How consistent are EXEL's earnings?
EXEL earnings data spans 1999-2025. The current earnings trend is +0.6% YoY. Historical data enables comparison across business cycles.