Exelixis, Inc. (EXEL) Earnings History
Annual and quarterly earnings data from 1999 to 2025
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EXEL EPS Growth (CAGR)
Compound annual growth rate of diluted earnings per share
CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.
EXEL Profitability Analysis
Margin trends over time
| Year | Gross Margin | Operating Margin | Net Margin |
|---|---|---|---|
| 2025 | 96.4% | 37.6% | 33.7% |
| 2024 | 96.5% | 27.9% | 24.0% |
| 2023 | 96.0% | 9.3% | 11.4% |
| 2022 | 96.4% | 12.5% | 11.3% |
| 2021 | 96.3% | 20.0% | 16.1% |
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Exelixis, Inc. (EXEL) Earnings Overview
As of May 6, 2026, Exelixis, Inc. (EXEL) reported trailing twelve-month net income of $833M, reflecting +58.0% year-over-year growth. The company earned $3.12 per diluted share over the past four quarters, with a net profit margin of 33.7%.
Looking at the long-term picture, EXEL's 5-year EPS compound annual growth rate (CAGR) stands at +51.4%, indicating exceptional earnings growth. The company achieved its highest annual net income of $783M in fiscal 2025, representing a new all-time high.
Exelixis, Inc. maintains industry-leading profitability with a gross margin of 96.4%, operating margin of 37.6%, and net margin of 33.7%. This margin structure demonstrates strong pricing power and operational efficiency. View revenue history →
Compared to peers including INCY ($1.43B net income, 25.0% margin), ALKS ($242M net income, 16.4% margin), JAZZ ($29M net income, -8.3% margin), EXEL has outperformed on profitability metrics. Compare EXEL vs INCY →
EXEL Earnings vs Peers
Earnings metrics vs comparable public companies
EXEL Historical Earnings Data (1999–2025)
27 years| Fiscal Year | Net Income | YoY % | Operating Income | EPS (Diluted) | Net Margin | Op. Margin |
|---|---|---|---|---|---|---|
| 2025 | $783M | +50.1% | $872M | $2.78 | 33.7% | 37.6% |
| 2024 | $521M | +150.9% | $605M | $1.76 | 24.0% | 27.9% |
| 2023 | $208M | +14.0% | $171M | $0.65 | 11.4% | 9.3% |
| 2022 | $182M | -21.1% | $201M | $0.56 | 11.3% | 12.5% |
| 2021 | $231M | +106.7% | $287M | $0.72 | 16.1% | 20.0% |
| 2020 | $112M | -65.2% | $110M | $0.35 | 11.3% | 11.1% |
| 2019 | $321M | -53.5% | $369M | $1.02 | 33.2% | 38.2% |
| 2018 | $690M | +347.4% | $439M | $2.21 | 80.8% | 51.4% |
| 2017 | $154M | +319.6% | $166M | $0.49 | 34.1% | 36.7% |
| 2016 | -$70M | +58.6% | -$28M | $-0.28 | -36.7% | -14.7% |
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Start ComparisonEXEL — Frequently Asked Questions
Quick answers to the most common questions about buying EXEL stock.
Is EXEL growing earnings?
EXEL EPS is $3.12, with earnings growth accelerating to +58.0%. This exceeds the 5-year CAGR of +51.4%. TTM net income reached $833M.
What are EXEL's profit margins?
Exelixis, Inc. net margin is +33.7%, with operating margin at +37.6%. Above-average margins indicate pricing power.
How consistent are EXEL's earnings?
EXEL earnings data spans 1999-2025. The accelerating earnings trend is +58.0% YoY. Historical data enables comparison across business cycles.