Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ACRV held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 8.3M | $11.6M | 0.0% | 26.431% | 0.12% |
| 2 | Sands Capital Alternatives, LLC | 2.1M | $3.0M | 0.0% | 6.726% | 0.70% |
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 888K | $1.2M | 0.0% | 2.814% | 0.00% |
| 4 | RENAISSANCE TECHNOLOGIES LLC | 758K | $1.1M | +19.6% | 2.404% | 0.00% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 722K | $1.0M | β | 2.288% | 0.00% |
| 6 | MARSHALL WACE, LLP | 560K | $779K | +13.0% | 1.776% | 0.00% |
| 7 | TWO SIGMA INVESTMENTS, LP | 389K | $541K | -33.4% | 1.234% | 0.00% |
| 8 | JANE STREET GROUP, LLC | 240K | $333K | -29.9% | 0.760% | 0.00% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 236K | $329K | +19.3% | 0.749% | 0.00% |
| 10 | BlackRock, Inc. | 209K | $290K | +1.9% | 0.662% | 0.00% |
| 11 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 159K | $221K | +270.4% | 0.504% | 0.00% |
| 12 | VANGUARD FIDUCIARY TRUST CO | 108K | $149K | β | 0.341% | 0.00% |
| 13 | STATE STREET CORP | 67K | $93K | 0.0% | 0.213% | 0.00% |
| 14 | XTX Topco Ltd | 67K | $93K | +225.1% | 0.212% | 0.00% |
| 15 | BLUEFIN CAPITAL MANAGEMENT, LLC | 42K | $76K | β | 0.133% | 0.01% |
| 16 | NORTHERN TRUST CORP | 49K | $68K | -23.3% | 0.155% | 0.00% |
| 17 | MORGAN STANLEY | 37K | $51K | -21.7% | 0.116% | 0.00% |
| 18 | UBS Group AG | 35K | $48K | -90.1% | 0.110% | 0.00% |
| 19 | PANAGORA ASSET MANAGEMENT INC | 34K | $47K | β | 0.107% | 0.00% |
| 20 | Squarepoint Ops LLC | 27K | $38K | +5.0% | 0.087% | 0.00% |
| 21 | PRELUDE CAPITAL MANAGEMENT, LLC | 24K | $33K | -50.0% | 0.076% | 0.00% |
| 22 | Marex Group plc | 20K | $28K | +100.0% | 0.063% | 0.00% |
| 23 | DIMENSIONAL FUND ADVISORS LP | 18K | $25K | 0.0% | 0.058% | 0.00% |
| 24 | BANK OF AMERICA CORP /DE/ | 17K | $23K | -5.3% | 0.052% | 0.00% |
| 25 | GOLDMAN SACHS GROUP INC | 15K | $20K | -87.7% | 0.047% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ACRV β a direct measure of their conviction.
Filings activity in ACRV during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new ACRV position in Q1 2026
Institutions that fully closed their ACRV position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 44 | 8.3% | 44.81% | 46.99 pp | $21M | 51% |
| Q4 2025 | 48 | +2.1% | 91.80% | +23.46 pp | $43M | +34% |
| Q3 2025 | 47 | 13% | 68.34% | +24.04 pp | $32M | +54% |
| Q2 2025 | 54 | 14% | 44.30% | 52.12 pp | $21M | 54% |
| Q1 2025 | 63 | +3.3% | 96.42% | 103.57 pp | $46M | 67% |
| Q4 2024 | 61 | +11% | 199.99% | +0.00 pp | $140M | 13% |
| Q3 2024 | 55 | +0.0% | 199.99% | +0.00 pp | $160M | +18% |
| Q2 2024 | 55 | β | 199.99% | β | $136M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ACRV stock.
Based on Q1 2026 13F filings, institutional ownership of Acrivon Therapeutics, Inc. Common Stock stands at 44.8%, held across 44 reporting institutions.
RA CAPITAL MANAGEMENT, L.P. is the largest reported institutional holder of ACRV, with approximately 8,340,508 shares worth $0.01B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of ACRV, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, JANE STREET GROUP, LLC.
Our composite Smart Money Score for ACRV is 45 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
11 institutions opened new positions in ACRV during Q1 2026, while 15 fully exited. 3 added to existing positions and 29 trimmed.
ACRV institutional ownership fell by 46.99 percentage points quarter-over-quarter, with a net change of -4 holders.
The top 10 institutions account for 94.8% of all reported 13F value in ACRV, and the top 25 account for 99.6%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.