Cash conversion remains deeply negative — free cash flow was negative in all ten trailing quarters (ranging from -$14.7M to -$53.3M), with cumulative operating cash flow of about -$302.7M exceeding cumulative net losses of roughly -$188.1M by ~$115M, while no capital was returned to shareholders amid a $63.9M acquisition outflow in 2026Q2.
Agenus Inc. (AGEN) cash flow statement — 27-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 |
|---|
| Cash from Operations | -98.5M | -158.31M | -158.31M | -224.2M | -175.37M | 10.14M | -139.1M | -18.68M | -131.09M | -94.23M | -79.96M | -47.18M | -38.23M | -19.53M | 1.01M | -16.25M | -14.76M | -24.19M | -28.91M | -26.69M | -44.94M | -66.33M | -60.22M | -51.19M | -50.83M | -36.83M | -15.13M | -13.5M |
| Operating CF Margin % | - | -138.63% | -153.02% | -143.43% | -178.91% | 3.43% | -157.76% | -12.45% | -356.39% | -219.76% | -354.23% | -190.09% | -548.01% | -641.48% | 6.34% | -589.63% | -439.28% | -725.65% | -1090.54% | -480.72% | -6492.82% | -10528.27% | -8517.5% | -1150.37% | -1490.06% | -808.47% | -3419.21% | -13500% |
| Operating CF Growth % | 19.73% | 0% | 29.39% | -27.84% | -1828.66% | 107.29% | -644.55% | 85.75% | -39.13% | -17.84% | -69.5% | -23.38% | -95.74% | -2028.99% | 106.23% | -10.1% | 39% | 16.32% | -8.32% | 40.61% | 32.25% | -10.13% | -17.66% | -0.7% | -38.04% | -143.33% | -12.11% | - |
| Net Income | 92.56M | -232.27M | -232.27M | -257.44M | -230.66M | -28.72M | -182.89M | -111.56M | -162.04M | -120.69M | -127M | -87.88M | -42.49M | -30.07M | -11.32M | -23.28M | -21.91M | -30.32M | -28.7M | -36.8M | -51.88M | -74.1M | -68.75M | -65.93M | -55.88M | -73.54M | -46.73M | -18.1M |
| Depreciation & Amortization | 4.73M | 13.34M | 13.34M | 13.59M | 6.95M | 6.79M | 7.18M | 6.66M | 6.29M | 6.01M | 4.95M | 14.2M | 1.58M | 586.34K | 1.62M | 2.25M | 3.44M | 4.11M | 4.67M | 5.42M | 5.66M | 5.59M | 4.81M | 6.49M | 5.47M | 4.15M | 1.68M | 1M |
| Stock-Based Compensation | 11.41M | 17.39M | 17.39M | 22.87M | 18.34M | 19.58M | 10.42M | 9.89M | 7.63M | 12.43M | 13.19M | 7.44M | 4.67M | 4.13M | 4.3M | 2.65M | 3.15M | 3.13M | 5.58M | 3.06M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 58K | 10.91M | 23.56K | 14.73K | -5.39M | 4.58K | 2.73M | 11.03K | 23.31M | -1.97M | -2.28M | -13.24M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -215.29M | 15.89M | 10.62M | -13.98M | 5.92M | 22.25M | 17.25M | 17.58M | 5.95M | 14.49M | 18.48M | 17.83M | 4M | 1.82M | 3.14M | -19.11M | 2.14M | 3.97M | 2.24M | 2.07M | 4.91M | 228.46K | 4.15M | 1.53M | 2.39M | 35.82M | 28.27M | 5M |
| Working Capital Changes | 8.71M | 27.33M | 32.6M | 10.76M | 24.08M | -9.74M | 8.95M | 58.68M | 170.05K | -6.48M | 10.4M | 6.63M | -6.01M | 1.27M | 3.26M | -2.08M | 386.7K | -2.8M | 535.84K | -444.23K | -3.62M | 1.96M | -432.84K | 6.73M | -2.81M | -3.25M | 1.65M | -1.4M |
| Change in Receivables | -14.39M | -1.73M | 25.34M | -23.46M | 122K | -394K | 16.19M | -15.36M | 196.35K | 10.22M | -1.55M | -9.33M | 1.2K | 551.13K | -552.33K | 35K | -35K | -2.26M | 318.71K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 55K | 24K | 8.71K | 17.63M | 7.5K | -95.7K | 16.02K | 4.05K | 6.36K | 297.6K | -97.66K | 284.5K | -72.23K | -187.59K | -81.31K | 58.15K | -8.95K | -158.42K | -702K | 219.56K | 0 |
| Change in Payables | -13.19M | 23.5M | 2.01M | 21.37M | 6.49M | 10.82M | 2.77M | -234K | 5.37M | 1.65M | 419.71K | 2.67M | -45.9K | 189.64K | -181.85K | 4.43K | -198.12K | 296.09K | -133.94K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | 70.08M | 27K | 27K | 3.4M | -33.61M | -43.15M | -4.44M | -4.66M | -3.59M | 2.06M | 17.6M | -31.23M | -16.81M | -363.52K | -103.44K | -29.46K | 9.93M | 2.16M | -4M | 13.19M | 15.39M | 41.77M | 3.93M | -32.53M | -28.17M | 2.99M | -1.63M | -4.9M |
| Capital Expenditures | 0 | -576K | -576K | -9.95M | -53.06M | -33.81M | -3.47M | -4.66M | -3.6M | -3.12M | -12.52M | -3.59M | -2.82M | -813.52K | -103.44K | -54.55K | -130.44K | -243.87K | -206.01K | -11.21K | -329.89K | -2.66M | -3.97M | -18.54M | -2.31M | -1.67M | -2.64M | -4.9M |
| CapEx % of Revenue | 0% | 0.5% | 0.56% | 6.37% | 54.13% | 11.44% | 3.93% | 3.1% | 9.78% | 7.28% | 55.46% | 14.47% | 40.42% | 26.72% | 0.65% | 1.98% | 3.88% | 7.31% | 7.77% | 0.2% | 47.66% | 422.28% | 561.48% | 416.6% | 67.65% | 36.55% | 596.86% | 4900% |
| Acquisitions | 0 | 0 | 0 | 0 | -2.92M | 0 | -975K | 0 | 6.19K | 120K | 0 | -7.18M | 514.47K | 0 | 0 | 0 | 0 | 53.55K | 0 | 0 | 33.26K | 0 | 12.57M | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 69.26M | 24K | 24K | 3.36M | 22M | 5.66M | 0 | 0 | 6.19K | 120K | 30.12M | -20.46M | -14.51M | 450K | 0 | 23.88K | 50.3K | 2.34M | 2M | 0 | 2.98M | 1.96M | 3.02M | -7.27M | -300K | 1.66M | 1.02M | 0 |
| Cash from Financing | 35.75M | 122.84M | 122.84M | 119.87M | 95.83M | 225.26M | 183.85M | 31.32M | 128.28M | 80.54M | -2.46M | 189.58M | 52.81M | 25.78M | 9.81M | 7.24M | 4.54M | 17.63M | 42.9M | 3.76M | 20.55M | 41.79M | 47.85M | 107.8M | 51.27M | -1.44M | 66.48M | 42.6M |
| Debt Issued (Net) | -2.11M | 2.35M | 9.52M | -8.93M | -490K | -1.32M | 2.96M | -320K | -162.13M | 14.52M | -144.66K | 107.89M | -3.37M | -608.85K | -100K | 0 | -6.24M | -255K | -2.93M | 0 | 20.98M | 42.25M | -5.95M | 15.32M | -5.55M | -2.23M | -906K | 2.1M |
| Equity Issued (Net) | 25.07M | 36.22M | 38.82M | 127.98M | 95.42M | 218.99M | 176.42M | 30M | 86.03M | 66.02M | 1.5M | 109.67M | 0 | 26.46M | 9.87M | 7.98M | 11.53M | 18.53M | 46.57M | 65.83K | 469.3K | 327.3K | 54.62M | 92.59M | 562.58K | 218.89K | 601K | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -460.96K | 0 | -592.88K | -790.5K | -790.5K | -790.5K | -790.5K | -790.5K | -790.5K | -790.5K | -817.01K | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | -87K | 0 | -5.17M | -3.79M | -1.65M | 0 | 0 | 0 | -527K | -667.05K | 0 | 0 | 0 | -592.88K | 0 | 0 | -54.94K | -257.68K | -12.17K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 12.79M | 84.27M | 74.5M | 807K | 898K | 7.59M | 4.47M | 1.64M | 204.39M | 775 | -3.82M | -27.98M | 56.64M | -73.79K | 632.71K | 54.47K | 49.32K | 141.31K | 46.56K | 4.49M | -101.04K | 0 | 0 | -110.93K | 56.25M | 572.34K | 66.79M | 40.5M |
| Net Change in Cash | 8.99M | -35.71M | -35.71M | -101.56M | -113.26M | 192.09M | 40.7M | 8.75M | -7.13M | -11.26M | -65.25M | 110.99M | -1.64M | 5.88M | 10.72M | -9.03M | -284.84K | -4.4M | 9.99M | -9.74M | -9M | 17.24M | -8.44M | 24.08M | -27.74M | -35.27M | 49.72M | 24.2M |
| Free Cash Flow | -98.5M | -158.89M | -158.89M | -234.16M | -228.44M | -23.67M | -142.56M | -23.34M | -134.69M | -97.35M | -92.48M | -50.77M | -41.05M | -20.35M | 909.16K | -16.3M | -14.89M | -24.44M | -29.12M | -26.7M | -45.27M | -68.99M | -64.19M | -69.72M | -53.14M | -38.49M | -17.78M | -18.4M |
| FCF Margin % | -74.23% | -139.14% | -153.57% | -149.8% | -233.04% | -8.01% | -161.69% | -15.55% | -366.17% | -227.03% | -409.7% | -204.56% | -588.42% | -668.19% | 5.7% | -591.61% | -443.16% | -732.96% | -1098.31% | -480.92% | -6540.48% | -10950.56% | -9078.97% | -1566.96% | -1557.71% | -845.03% | -4016.07% | -18400% |
| FCF Growth % | 22.97% | 0% | 32.14% | -2.5% | -865.12% | 83.4% | -510.83% | 82.67% | -38.36% | -5.26% | -82.17% | -23.66% | -101.78% | -2337.94% | 105.58% | -9.5% | 39.07% | 16.07% | -9.04% | 41.01% | 34.38% | -7.46% | 7.93% | -31.21% | -38.06% | -116.53% | 3.39% | - |
| FCF per Share | -2.38 | -5.34 | -7.40 | -13.09 | -16.22 | -2.07 | -16.53 | -3.46 | -24.32 | -19.78 | -21.24 | -12.98 | -13.74 | -1.50 | 0.04 | -0.82 | -0.92 | -1.86 | -2.76 | -3.44 | -5.93 | -9.08 | -8.62 | -10.73 | -9.69 | -8.21 | -4.33 | -4.80 |
| FCF Conversion (FCF/Net Income) | -1.06x | -1376.65x | 0.70x | 0.91x | 0.80x | -0.42x | 0.77x | 0.17x | 0.82x | 0.78x | 0.63x | 0.54x | 0.90x | 0.65x | -0.09x | 0.70x | 0.67x | 0.80x | 1.01x | 0.73x | 0.87x | 0.90x | 1.07x | 0.78x | 0.91x | 0.50x | 0.32x | 0.75x |
| Interest Paid | 718K | 0 | 2.28M | 3.17M | 1.14M | 1.15M | 1.18M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying AGEN stock.
Agenus Inc. (AGEN) generated $-158.3M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Agenus Inc. (AGEN) reported negative free cash flow of $158.9M in 2025, indicating capital requirements exceeded cash from operations.
Agenus Inc. (AGEN) spent $0.6M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Agenus Inc. (AGEN) spent $0.1M on share repurchases. This shows the company's commitment to returning capital to its equity investors.
Key Metrics
Top Statement Risk
Non-operating gains masking persistent cash burn
Metrics are mathematically derived from official filings.
Earnings Fail to Convert Into Cash
Agenus reported positive net income of $63.9M in 2025Q3 and $39.2M in 2026Q1 yet operating cash flow remained negative at -$14.7M and -$36.0M respectively, per its quarterly financial statements — indicating headline earnings are substantially driven by non-operating items rather than cash-generative operations.
The gap between net income and operating cash flow is not a timing artifact; it appears in every quarter where profits were reported. In 2026Q2, the company showed $0 net income against -$31.2M of operating cash outflow, suggesting the operating cash burn continues even when reported earnings neutralize. For investors, this pattern implies that reported profitability metrics overstate Agenus's economic performance and that cash generation — the true measure of a biotech's runway — remains structurally impaired.
Cumulative Cash Burn Exceeds Reported Losses
Over the trailing ten quarters, Agenus's cumulative operating cash flow of approximately -$302.7M significantly exceeds its cumulative net loss of roughly -$188.1M — a ~$115M divergence — as calculated from the company's reported quarterly filings, indicating material non-cash charges and working capital absorption beyond the income statement.
A cumulative cash outflow of this magnitude relative to reported losses signals that investors relying on net income alone would materially underestimate the firm's capital consumption. The gap is partly explained by depreciation and stock-based compensation recognized as non-cash charges, but also by working capital swings that have consumed cash in multiple quarters. This divergence warrants monitoring of whether future reported profits can be sustained without continuing the cumulative cash drain.
Free Cash Flow Deepens Into Sustained Burn
Agenus's free cash flow was negative in every quarter over the trailing two years, ranging from -$14.7M in 2025Q3 to -$53.3M in 2024Q3, with FCF margins never improving beyond -2.1%, as reflected in its reported financial statements — indicating that even periods of reported profitability have not stabilized cash generation.
The trajectory does not show a clear inflection toward self-sustaining cash generation; the least negative quarter (-$14.7M in 2025Q3) coincided with a large non-operating gain rather than operational improvement. Recent quarters (2026Q1 and 2026Q2) saw FCF margins of -106.6% and -90.4%, respectively, suggesting that any revenue growth achieved is still outpaced by operating outflows. Investors should monitor whether declining SG&A and rising revenue — as noted in the income statement analysis — translate into positive operating cash flow in coming quarters.
No Shareholder Returns Amid Acquisition Outflows
Agenus returned zero capital to shareholders via dividends or buybacks across all ten quarters while deploying $63.9M on an acquisition in 2026Q2 — funds that match, in magnitude, a $63.9M inflow in 2026Q1 — as reported in its cash flow statements, suggesting strategic capital reallocation rather than deleveraging or buybacks.
The absence of any buybacks or dividends is consistent with a pre-commercialization biotech deploying capital into pipeline assets rather than returning cash, but the scale of the acquisition outflow is notable given the company's sustained operating cash burn. The offsetting $63.9M inflow in 2026Q1 suggests the acquisition may have been asset-disposal-funded or structured, which warrants further investigation. For investors, the key question is whether the acquired asset generates meaningful cash or further research spend — neither outcome is visible from the cash flow statement alone.
What the Cash Flow Statement Obscures
Agenus's cash flow statement does not separate operating outflows from potential restructuring or litigation charges, and stock-based compensation of $4.7M in 2026Q2 added to non-cash charges that flattered the reported operating loss, per its quarterly disclosures — meaning the true underlying operating burn may differ from what headline figures suggest.
Investors should note that working capital changes have swung from +$23.8M (2026Q2) to -$23.8M (2026Q1), indicating volatile receivables or payables patterns that may mask recurring cash needs. Depreciation and amortization of $517K in 2026Q2 is minimal, suggesting the company holds few tangible assets — consistent with its research-stage profile — but also implying limited asset-backed financing flexibility. The 2026Q2 income statement anomaly noted in prior analysis ($0 gross profit yet positive operating income) further warrants scrutiny of how operating cash flow is being classified in recent periods.