Agenus Inc. (AGEN) Financial Ratios
27 years of historical data (1999–2025) · Healthcare · Biotechnology
EV/EBITDA
N/A
—
5yr avg: 15.47
30Y Low15.5·High15.5
P/FCF
N/A
—
5yr avg: N/A
P/B Ratio
N/A
—
5yr avg: 15.39
30Y Low5.0·High136.0
ROE
N/A
—
5yr avg: -49.9%
30Y Low-458%·High-35%
Debt/EBITDA
N/A
—
5yr avg: 1.79
30Y Low1.8·High1.8
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
AGEN Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Agenus Inc. currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $125M | $93M | $59M | $296M | $676M | $737M | $549M | $549M | $264M | $321M | $359M |
| Enterprise Value | $457M | $425M | $113M | $313M | $576M | $503M | $504M | $511M | $224M | $424M | $413M |
| P/E Ratio → | -882.35 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 1.09 | 0.82 | 0.57 | 1.90 | 6.90 | 2.49 | 6.22 | 3.66 | 7.17 | 7.48 | 15.89 |
| P/B Ratio | — | — | — | — | — | 15.39 | — | — | — | — | — |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | 72.66 | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
AGEN EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 3.72 | 1.09 | 2.01 | 5.88 | 1.70 | 5.72 | 3.41 | 6.09 | 9.88 | 18.30 |
| EV / EBITDA | — | — | — | — | — | 15.47 | — | — | — | — | — |
| EV / EBIT | — | 8.15 | — | — | — | 13.61 | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — | — |
AGEN Profitability
Margins and return-on-capital ratios measuring operating efficiency
Agenus Inc. earns an operating margin of -18.0%. Operating margins have expanded from -102.1% to -18.0% over the past 3 years, signaling improving operational efficiency.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 29.6% | 29.6% | -50.8% | -52.1% | -101.2% | 38.4% | -64.4% | -12.2% | -238.7% | -170.8% | -320.7% |
| Operating Margin | -18.0% | -18.0% | -116.4% | -102.1% | -183.0% | 8.7% | -133.0% | -46.7% | -336.6% | -242.1% | -476.1% |
| Net Profit Margin | 0.1% | 0.1% | -219.6% | -157.2% | -224.5% | -8.1% | -205.2% | -71.7% | -434.1% | -281.5% | -562.6% |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | — | — | — | — | -49.9% | — | — | — | — | -803.7% |
| ROA | 0.1% | 0.1% | -84.1% | -67.6% | -50.0% | -7.0% | -97.8% | -73.8% | -116.2% | -81.7% | -63.6% |
| ROIC | — | — | — | — | — | — | — | — | — | -369.4% | -562.5% |
| ROCE | — | — | -383.2% | -112.9% | -67.2% | 13.1% | -199.1% | -138.2% | -164.8% | -104.8% | -65.3% |
AGEN Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
Net debt stands at $332M ($335M total debt minus $3M cash). Interest coverage of just 0.9x is concerning — the company has limited headroom to absorb earnings volatility before struggling with debt service.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | — | — | — | 1.22 | — | — | — | — | — |
| Debt / EBITDA | — | — | — | — | — | 1.79 | — | — | — | — | — |
| Net Debt / Equity | — | — | — | — | — | -4.88 | — | — | — | — | — |
| Net Debt / EBITDA | — | — | — | — | — | -7.18 | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — | — |
| Interest Coverage | 0.94 | 0.94 | -0.97 | -1.63 | -2.73 | 0.56 | -1.99 | -1.69 | -5.41 | -5.40 | -6.33 |
AGEN Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
The current ratio of 0.41x is below 1.0, meaning current liabilities exceed current assets.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 0.41 | 0.41 | 0.21 | 0.44 | 1.13 | 2.12 | 0.88 | 0.71 | 1.10 | 1.30 | 2.24 |
| Quick Ratio | 0.41 | 0.41 | 0.21 | 0.44 | 1.05 | 1.99 | 0.88 | 0.65 | 1.10 | 1.30 | 2.23 |
| Cash Ratio | 0.01 | 0.01 | 0.18 | 0.30 | 1.02 | 1.96 | 0.77 | 0.51 | 0.78 | 1.07 | 1.87 |
| Asset Turnover | — | 0.50 | 0.46 | 0.50 | 0.24 | 0.63 | 0.41 | 0.97 | 0.27 | 0.31 | 0.14 |
| Inventory Turnover | — | — | — | — | 14.26 | 8.94 | — | 22.69 | 2245.42 | 1460.86 | 1076.77 |
| Days Sales Outstanding | — | 5.85 | 1.44 | 60.33 | 10.21 | 1.87 | 4.79 | 39.63 | 9.31 | 9.66 | 183.56 |
AGEN Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Agenus Inc. returns 0.1% to shareholders annually primarily through share buybacks.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.1% | 0.1% | 0.0% | 1.7% | 0.6% | 0.2% | 0.0% | 0.0% | 0.0% | 0.2% | 0.2% |
| Total Shareholder Yield | 0.1% | 0.1% | 0.0% | 1.7% | 0.6% | 0.2% | 0.0% | 0.0% | 0.0% | 0.2% | 0.2% |
| Shares Outstanding | — | $30M | $21M | $18M | $14M | $11M | $9M | $7M | $6M | $5M | $4M |
Peer Comparison
Compare AGEN with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 AGENYou | $125M | -882.4 | — | — | 29.6% | -18.0% | — | — | — |
 NKTR | $1B | -6.3 | — | — | 100.0% | -236.8% | -217.9% | -57.2% | — |
 INCY | $20B | 15.3 | 11.6 | 14.5 | 91.5% | 26.1% | 29.9% | 51.1% | 0.0 |
 EXEL | $13B | 18.7 | 14.3 | 15.6 | 96.4% | 37.6% | 35.5% | 32.1% | 0.2 |
 RCUS | $2B | -7.4 | — | — | 96.0% | -156.3% | -63.3% | -64.1% | — |
 MGNX | $263M | -3.5 | — | — | 71.1% | -48.7% | -86.9% | -144.1% | — |
 ALKS | $7B | 31.5 | 22.9 | 15.6 | 86.7% | 17.2% | 14.7% | 18.9% | 0.2 |
 FATE | $244M | -1.8 | — | — | -94.1% | -2222.4% | -51.8% | -36.5% | — |
 IMVT | $7B | -12.8 | — | — | — | — | -64.8% | — | — |
 TGTX | $8B | 19.2 | 67.4 | — | 83.7% | 20.0% | 102.8% | 16.4% | 2.1 |
 CLDX | $2B | -8.3 | — | — | 100.0% | -19160.0% | -40.6% | -35.2% | — |
| Healthcare Median | — | 22.1 | 14.2 | 18.5 | 63.9% | -4.3% | -32.6% | -11.6% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 27 years · Updated daily
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AGEN — Frequently Asked Questions
Quick answers to the most common questions about buying AGEN stock.
What is Agenus Inc.'s P/E ratio?
Agenus Inc.'s current P/E ratio is -882.4x. This places it at the 50th percentile of its historical range.
Is AGEN stock overvalued?
Based on historical data, Agenus Inc. is trading at a P/E of -882.4x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
What are Agenus Inc.'s profit margins?
Agenus Inc. has 29.6% gross margin and -18.0% operating margin.