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EXELExelixis, Inc.
$69.57$17.5B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
Financial Statements
Income StatementBalance SheetCash FlowRatios & Margins
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P/E HistoryRevenue HistoryEarnings HistoryDividend HistoryTotal Return
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EXEL logo

Exelixis, Inc.

EXEL
NASDAQ · Oncology Biotech
$69.57
At close - Nov 6, 4:00 PM EST - USD
Market Cap$17.49B
P/E20.1x
52W High$73.69
Volume2M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q3

Margin Strength Meets Volatile Cash Conversion at Exelixis

Exelixis has re-established revenue momentum, with 2026Q3 revenue rising 10.2% year over year to $658.7M after a mid-2025 dip, while gross margin held near-saturated levels between 95.6% and 97.2% and operating margin expanded from 25.2% to 40.8% over the observed window.

GrowthMixed
ProfitabilityStrong
ValuationAttractive
TechnicalsStrong
Explore valuation models
MARKET ACTION

EXEL price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

11/12 Beats

EPS beat 11 of last 12 quarters

02

Valuation risk

-43% Peers

P/E is 43% below peer median

03

Market leadership

RS 93 · Leader

High momentum (Outperforming 93% of market)

04

Strong Uptrend

Strong Trend

Price > 20DMA > 50DMA > 200DMA

Next CatalystEstimated earnings · Jan 29
01

Build the investment case

Start with the evidence for owning the stock and the risks that can break the thesis.

EXECUTIVE THESIS

The Investment Case

Full Analysis
Fundamental Trajectory

Revenue recovered to $658.7M in 2026Q3 (up 10.2% year over year) with operating margin expanding from 25.2% in 2024Q3 to 40.8%, suggesting operating income is scaling well ahead of revenue against a stable overhead base.

Analyst Consensus-23.8% target
Hold(33 analysts)
15 Buy18 Hold0 Sell

The Bull Case

Upside Catalysts

Bullish analyst coverage

Multiple bullish theses on Exelixis, Inc. have been highlighted by Business Invest's Substack and Investing With Purpose, indicating strong analyst confidence in the stock.

Strong valuation metrics

EXEL's trailing and forward P/E ratios of 18.52 and 15.24 (as of January 13th) suggest attractive valuation relative to earnings potential.

Recent price performance

The stock was trading at $44.08 as of January 13th, showing potential upward momentum from previous levels of $37.42.

The Bear Case

Key Downside Risks

Market performance

Price History →

Trailing total returns as of 11/7/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
EXEL+59.64%
S&P 500 (^GSPC)+7.63%
1-Year Return
EXEL+70.51%
S&P 500 (^GSPC)+9.69%
3-Year Return
EXEL+233.83%
S&P 500 (^GSPC)+71.41%
5-Year Return
EXEL+270.84%
S&P 500 (^GSPC)+59.13%
02

Test the fundamentals

Check whether operating performance supports the current valuation.

VALUATION & INTRINSIC VALUE

Valuation Scenarios

Valuation Analysis
Trailing P/EMedian
20.1x
Forward P/EExpansion
18.7x
EV/EBITDA40th %ile
16.7x
FCF YieldCash Flow
6.6%

Valuation vs 5-Year History

Multiple Range
Metric
Current
5Y Median
Historical Range
Percentile
P/E
20.1x
25.4x
40th· Fair
EV/EBITDA
16.7x
17.6x
40th· Fair
Price/FCF
15.2x
17.5x
20th· Low
Current Multiple
5Y Median (50th %ile)

Intrinsic Value Scenarios

DCF Projection
Bear$45.28-34.9%
Base (Fair)$68.00-2.3%
Bull$103.01+48.1%
$45.28 Bear$68.00 Base$103.01 Bull
Current Market Price: $69.57
Trades at a 2.3% premium to Base DCF ($68.00)
Open DCF & Valuation Models →Chart Terminal ↗

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$2.32B+7.0% YoY
Net income FY25
$783M+50.1% YoY
Free cash flow FY25
$844M+33.2% YoY
Operating margin FY25
37.6%+9.7 pts YoY
ROIC (FY25)32.1%
Avg ROIC 5Y16%
ROE (TTM)45.5%
Piotroski Score7 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate11/12 (92%)
Revenue Beat Rate7/12 (58%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Oct 29, 2026
$0.94+6.0%
vs $0.89
$659M+1.9%
vs $647M
Q3 2026
Aug 5, 2026
$0.91+6.7%
vs $0.85
$629M-1.2%
vs $636M
Q2 2026
May 5, 2026
$0.87+13.7%
vs $0.77
$611M+0.5%
vs $608M
Q1 2026
Feb 10, 2026
$0.94+22.1%
vs $0.77
$599M+0.4%
vs $597M
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
Zacks Investment Research·5d ago
Exelixis (EXEL) International Revenue in Focus: Trends and Expectations

Evaluate Exelixis' (EXEL) reliance on international revenue to better understand the company's financial stability, growth prospects and potential stock price performance.

Zacks Investment Research·Oct 30, 2026
EXEL Q3 Earnings Beat Estimates on Strong Cabometyx Sales

Exelixis tops Q3 2026 earnings and revenue estimates as Cabometyx sales grow, share repurchases accelerate and its zanzalintinib pipeline advances.

Seeking Alpha·Oct 29, 2026
Exelixis, Inc. (EXEL) Q3 2026 Earnings Call Transcript

Exelixis, Inc. (EXEL) Q3 2026 Earnings Call Transcript

MarketBeat·Oct 29, 2026
What Exelixis (EXEL) Said on Its Q3 Earnings Call

Exelixis NASDAQ: EXEL reported third-quarter 2026 revenue of approximately $659 million, supported by continued growth in its cabozantinib franchise and progress toward a potential launch of zanzalintinib in colorectal cancer.

Filtered for Exelixis, Inc.More Headlines
04

Compare before deciding

Benchmark EXEL against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Exelixis, Inc. (EXEL)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
EXEL logoEXELExelixis, Inc.Current
$69.57$17.49B20.106.98%35.45%45.54%—
INCY logoINCYIncyte Corporation
$119.65$24.25B60.2821.22%6.71%7.11%—
ALKS logoALKSAlkermes plc
$45.90$7.7B-9999.00-5.25%-0.02%-0.02%—
JAZZ logoJAZZJazz Pharmaceuticals plc
$234.76$14.75B73.754.88%4.37%4.62%—
IONS logoIONSIonis Pharmaceuticals, Inc.
$39.42$6.55B-11.5533.87%-64.64%-110.84%—
HALO logoHALOHalozyme Therapeutics, Inc.
$103.63$12.29B26.1837.55%26.93%544.26%—

Compare EXEL vs Peers

Exelixis, Inc. (EXEL) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs INCY

Most directly comparable listed peer for EXEL.

Scale Benchmark

vs MRK

Larger-name benchmark to compare EXEL against a more recognizable public peer.

Peer Set

Compare Top 5

vs INCY, ALKS, JAZZ, IONS

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

EXEL SEC Filings & Documents

Exelixis, Inc. (EXEL) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Oct 29, 2026·SEC

Material company update

Aug 5, 2026·SEC

Material company update

May 29, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 10, 2026·SEC

FY 2025

Feb 11, 2025·SEC

FY 2024

Feb 6, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Oct 29, 2026·SEC

FY 2026

Aug 5, 2026·SEC

FY 2026

May 5, 2026·SEC

Get notified when EXEL posts new earnings or crosses analyst targets

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EXEL Frequently Asked Questions

Exelixis, Inc. (EXEL) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Exelixis, Inc.'s revenue?

Exelixis, Inc. (EXEL) reported $2.50B in revenue over the trailing twelve months. Revenue was $2.32B in fiscal year 2025. That is 21996% more than the $10.5M of fiscal year 1999.

How fast is Exelixis, Inc. growing?

Exelixis, Inc. (EXEL) grew revenue by 9.1% over the trailing twelve months, compared with the twelve months before.

Is EXEL profitable?

Yes. Exelixis, Inc. (EXEL) earned $885.1M in net income over the trailing twelve months (a 35.5% net margin).

Dividend & Returns
What is EXEL's return on equity?

Exelixis, Inc. (EXEL) had a return on equity (ROE) of 45.5% over the trailing twelve months. That is well above the market's typical 10-15%.

What is Exelixis, Inc.'s free cash flow?

Exelixis, Inc. (EXEL) generated $1.15B in free cash flow over the trailing twelve months.

What if you invested $1,000 in EXEL back in 1999?

Total return calculator · dividends reinvested · 27+ years of data

See returns →