Last 47 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -1964.71 | — | 0.82 | — | 0.50 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 1.82 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 2.44 | 0.92 | 0.95 | 0.81 | 1.05 | 1.25 | 0.38 | 0.57 | 1.18 | 3.75 | 2.06 | 0.92 | 4.39 | 5.56 | 5.48 | 6.53 | 6.46 | 6.42 | 6.12 | 10.33 | 1.28 |
| — | -26.7% | +146.9% | +41.1% | -11.0% | -66.7% | -81.3% | -37.8% | -73.2% | -32.5% | -62.4% | -85.9% | -31.9% | -13.5% | -10.6% | -36.8% | +404.3% | -77.5% | -47.3% | +115.4% | -89.6% | |
| P/B Ratio | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 39.41 | 22.98 | 17.48 | 36.43 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 2.97 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | 3.26 | 6.35 | 7.38 | — | — | — | — | — | — | — | 81.63 | — | — | — | — | — | — | — | — | 1.44 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | 1.84 | 20.47 | 0.55 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 1.41 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 29.6% | — | 98.3% | 78.0% | 19.8% | -4.9% | 10.0% | -26.3% | -64.1% | -56.9% | 87.6% | 20.1% | -112.8% | -135.4% | -159.4% | -114.8% | -103.4% | -124.5% | -65.7% | -168.3% | 82.7% |
| — | — | +882.6% | +396.8% | +131.0% | +91.4% | -88.6% | -231.0% | +43.2% | +58.0% | +154.9% | +117.5% | -9.1% | -8.7% | -142.6% | +31.8% | -225.0% | +62.3% | +70.5% | -930.1% | +167.4% | |
| Operating Margin | -18.0% | 32.7% | 44.6% | 42.1% | -15.0% | -65.0% | -55.3% | -96.5% | -125.5% | -128.4% | -117.4% | -5.0% | -190.6% | -216.1% | -237.3% | -203.5% | -182.9% | -213.0% | -136.7% | -266.7% | 74.1% |
| — | +150.3% | +180.7% | +143.6% | +88.0% | +49.4% | +52.9% | -1824.8% | +34.2% | +40.6% | +50.5% | +97.5% | -4.2% | -1.5% | -73.6% | +23.7% | -346.7% | +65.6% | +61.3% | -284.0% | +131.6% | |
| Net Margin | 0.1% | — | 116.3% | -30.9% | 211.4% | -108.8% | -105.0% | -170.9% | -264.4% | -225.8% | -221.0% | -55.2% | -255.8% | -272.8% | -298.0% | -197.1% | -238.1% | -221.9% | -186.3% | -323.3% | 69.6% |
| — | — | +210.8% | +81.9% | +180.0% | +51.8% | +52.5% | -209.4% | -3.3% | +17.2% | +25.9% | +72.0% | -7.4% | -23.0% | -60.0% | +39.0% | -442.2% | +71.4% | +59.3% | -168.8% | +120.2% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | -6018.0% | -224.9% | -127.9% | -157.0% | 495.0% |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | -1315.7% | — | — | — | — | |
| ROA | 0.1% | — | 19.0% | -4.6% | 30.5% | -14.5% | -11.8% | -19.7% | -25.0% | -19.3% | -21.7% | -14.3% | -17.3% | -17.3% | -16.5% | -13.3% | -12.3% | -10.3% | -10.7% | -14.5% | 55.9% |
| — | — | +260.2% | +76.7% | +222.0% | +25.0% | +45.4% | -38.4% | -44.6% | -11.6% | -31.3% | -7.4% | -41.2% | -67.5% | -55.1% | +8.4% | -121.9% | +73.5% | +55.4% | +19.2% | +313.2% | |
| ROIC | — | — | 23.6% | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 5.88 | 2.33 | 1.22 | 1.54 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Debt / EBITDA | — | 3.51 | 19.47 | 22.33 | — | — | — | — | — | — | — | 93.19 | — | — | — | — | — | — | — | — | 0.29 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 0.41 | 0.34 | 0.38 | 0.41 | 0.47 | 0.06 | 0.11 | 0.21 | 0.19 | 0.37 | 0.24 | 0.44 | 0.63 | 0.84 | 1.08 | 1.13 | 1.45 | 1.81 | 1.78 | 2.12 | 2.05 |
| — | +497.8% | +244.2% | +100.4% | +151.7% | -84.6% | -52.9% | -53.1% | -70.7% | -55.8% | -78.1% | -61.1% | -56.4% | -53.7% | -39.5% | -46.7% | -29.3% | +228.8% | +81.7% | +141.5% | +140.5% | |
| Quick Ratio | 0.41 | 0.34 | 0.38 | 0.41 | 0.47 | 0.06 | 0.11 | 0.21 | 0.19 | 0.37 | 0.24 | 0.44 | 0.55 | 0.79 | 1.08 | 1.05 | 1.33 | 1.63 | 1.65 | 1.99 | 1.93 |
| — | +497.8% | +244.2% | +100.4% | +151.7% | -84.6% | -52.9% | -53.1% | -66.5% | -53.5% | -78.1% | -58.3% | -58.3% | -51.3% | -34.6% | -46.9% | -31.4% | +196.2% | +68.1% | +126.6% | +126.2% | |
| Interest Coverage | 0.94 | 0.74 | 3.67 | 0.34 | 5.85 | -1.26 | -1.06 | -1.26 | -0.88 | -0.73 | -1.15 | -0.10 | -2.46 | -2.96 | -3.27 | -3.28 | -2.63 | -2.59 | -2.33 | -3.08 | 11.69 |
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Includes 30+ ratios · 47 years · Updated daily
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Quick answers to the most common questions about buying AGEN stock.
Agenus Inc.'s current P/E is -1964.7x. The average P/E over the last 2 quarters is 0.7x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Agenus Inc.'s current operating margin is -18.0%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Agenus Inc.'s business trajectory between earnings reports.