Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ALXO held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | 13.0M | $26.1M | β | 23.995% | 0.28% |
| 2 | TCG Crossover Management, LLC | 13.0M | $26.1M | β | 23.995% | 0.75% |
| 3 | venBio Partners LLC | 12.9M | $25.8M | +32.8% | 23.761% | 9.21% |
| 4 | Redmile Group, LLC | 8.0M | $16.0M | +143.9% | 14.687% | 1.06% |
| 5 | Blackstone Inc | 5.8M | $11.7M | β | 10.745% | 0.05% |
| 6 | DRIEHAUS CAPITAL MANAGEMENT LLC | 5.7M | $11.5M | +303.0% | 10.575% | 0.08% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 4.2M | $8.4M | β | 7.708% | 0.00% |
| 8 | MARSHALL WACE, LLP | 3.8M | $7.5M | +14144.8% | 6.929% | 0.01% |
| 9 | Vivo Capital, LLC | 3.2M | $6.4M | β | 5.873% | 0.53% |
| 10 | Almitas Capital LLC | 3.2M | $6.4M | +25.1% | 5.853% | 1.44% |
| 11 | 5AM Venture Management, LLC | 3.1M | $6.1M | β | 5.638% | 1.70% |
| 12 | ORBIMED ADVISORS LLC | 2.9M | $5.7M | β | 5.286% | 0.12% |
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 2.0M | $4.0M | β | 3.688% | 0.01% |
| 14 | MILLENNIUM MANAGEMENT LLC | 2.0M | $4.0M | β | 3.667% | 0.00% |
| 15 | TWO SIGMA INVESTMENTS, LP | 1.6M | $3.2M | +148.0% | 2.928% | 0.00% |
| 16 | Squadron Capital Management LLC | 1.5M | $2.9M | β | 2.692% | 1.21% |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.4M | $2.7M | +639.3% | 2.513% | 0.00% |
| 18 | Ensign Peak Advisors, Inc | 951K | $1.9M | β | 1.753% | 0.00% |
| 19 | UBS Group AG | 915K | $1.8M | +5.6% | 1.687% | 0.00% |
| 20 | RENAISSANCE TECHNOLOGIES LLC | 733K | $1.5M | +73.2% | 1.351% | 0.00% |
| 21 | BANK OF AMERICA CORP /DE/ | 578K | $1.2M | +8.6% | 1.065% | 0.00% |
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 493K | $990K | +39.5% | 0.910% | 0.00% |
| 23 | BlackRock, Inc. | 448K | $898K | -0.6% | 0.826% | 0.00% |
| 24 | VANGUARD FIDUCIARY TRUST CO | 294K | $590K | β | 0.543% | 0.00% |
| 25 | STATE STREET CORP | 176K | $353K | +41.5% | 0.324% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ALXO β a direct measure of their conviction.
Filings activity in ALXO during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 68 | +26% | 199.99% | +168.11 pp | $187M | +575% |
| Q4 2025 | 54 | 10% | 31.88% | 18.41 pp | $28M | 37% |
| Q3 2025 | 60 | 3.2% | 50.29% | +37.04 pp | $44M | +280% |
| Q2 2025 | 62 | 27% | 13.25% | 10.68 pp | $11M | 45% |
| Q1 2025 | 85 | +0.0% | 23.93% | 48.59 pp | $21M | 67% |
| Q4 2024 | 85 | 9.6% | 72.52% | 127.47 pp | $63M | 78% |
| Q3 2024 | 94 | 14% | 199.99% | +0.00 pp | $283M | 0.5% |
| Q2 2024 | 109 | β | 199.99% | β | $285M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ALXO stock.
Based on Q1 2026 13F filings, institutional ownership of ALX Oncology Holdings Inc. stands at 200.0%, held across 68 reporting institutions.
RA CAPITAL MANAGEMENT, L.P. is the largest reported institutional holder of ALXO, with approximately 13,011,849 shares worth $0.03B as of Q1 2026.
Yes β 4 widely-followed marquee investors appear among the top 25 institutional holders of ALXO, including MILLENNIUM MANAGEMENT LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for ALXO is 76 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
27 institutions opened new positions in ALXO during Q1 2026, while 13 fully exited. 38 added to existing positions and 2 trimmed.
ALXO institutional ownership rose by 168.11 percentage points quarter-over-quarter, with a net change of +14 holders.
The top 10 institutions account for 78.1% of all reported 13F value in ALXO, and the top 25 account for 98.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
ALX Oncology Holdings Inc. (ALXO) Institutional Ownership