Free cash flow generation remains inconsistent, with margins varying from 3.5% in 2023Q4 to 48.4% in 2024Q4, reflecting the lumpy impact of acquisition-related outflows and working capital volatility.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | 10.76B | 9.96B | 11.49B | 8.47B | 9.72B | 9.26B | 10.5B | 9.15B | 11.3B | 11.18B | 10.35B | 9.08B | 8.55B | 6.29B | 5.88B | 5.12B | 5.79B | 6.34B | 5.99B | 5.4B | 5.39B | 4.91B | 3.7B | 3.57B | 2.25B | 1.48B | 1.63B | 1.08B | 1.04B | 902.9M | 822.6M |
| Operating CF Margin % | - | 27.1% | 34.38% | 30.05% | 36.93% | 35.65% | 41.29% | 39.17% | 47.57% | 48.92% | 45.03% | 41.9% | 42.64% | 33.68% | 34.07% | 32.85% | 38.44% | 43.27% | 39.91% | 36.56% | 37.77% | 39.51% | 35.04% | 42.68% | 40.72% | 36.86% | 47.4% | 33.56% | 39.42% | 38.49% | 37.42% |
| Operating CF Growth % | 14.86% | -13.33% | 35.64% | -12.86% | 4.97% | -11.77% | 14.72% | -19% | 1.06% | 7.95% | 14.07% | 6.1% | 35.99% | 6.95% | 14.91% | -11.54% | -8.66% | 5.81% | 10.87% | 0.22% | 9.73% | 32.84% | 3.66% | 58.6% | 51.93% | -9.45% | 52.01% | 3.25% | 15.35% | 9.76% | 6.39% |
| Net Income | 7.8B | 7.71B | 4.09B | 6.72B | 6.55B | 5.89B | 7.26B | 7.84B | 8.39B | 1.98B | 7.72B | 6.94B | 5.16B | 5.08B | 4.34B | 3.68B | 4.63B | 4.61B | 4.2B | 3.17B | 2.95B | 3.67B | 2.36B | 2.26B | -1.39B | 1.12B | 1.14B | 1.1B | 863.2M | 644.3M | 679.8M |
| Depreciation & Amortization | 3.78B | 5.17B | 5.59B | 4.07B | 3.42B | 3.4B | 3.6B | 2.21B | 1.95B | 1.96B | 2.1B | 2.11B | 2.09B | 1.29B | 1.09B | 1.06B | 1.02B | 1.05B | 1.07B | 1.2B | 963M | 841M | 734M | 686.5M | 447.3M | 265.9M | 211.8M | 176.8M | 143.8M | 117.1M | 100.3M |
| Stock-Based Compensation | 284M | 0 | 530M | 431M | 401M | 341M | 330M | 308M | 311M | 329M | 311M | 322M | 408M | 403M | 362M | 341M | 353M | 284M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | -471M | -721M | -1.23B | -1.27B | -1.2B | -453M | -287M | -289M | -363M | -1.33B | 183M | -607M | -108M | -189M | 28M | -399M | -167M | 47M | -46M | 136M | -540M | -95M | 57M | -189.6M | 174.7M | -148.3M | 0 | 9.8M | -5.6M | -31.4M | 25.6M |
| Other Non-Cash Items | 325M | -221M | 141M | -991M | 1.28B | 1.28B | -195M | -186M | 386M | 334M | 32M | -399M | -116M | 103M | 104M | 69M | 258M | 242M | 321M | 1.26B | 1.63B | 481M | 918M | 367.6M | 3.27B | 342.3M | 405M | 16.8M | 33.1M | 36.1M | 52.8M |
| Working Capital Changes | -962M | -1.98B | 2.37B | -484M | -733M | -1.19B | -216M | -731M | 622M | 7.91B | 1M | 714M | 1.12B | -393M | -45M | 365M | -301M | 109M | 427M | -441M | 463M | 10M | -375M | 442.6M | -249.6M | -99.4M | -120.7M | -224.5M | -4.3M | 136.8M | -35.9M |
| Change in Receivables | -1.37B | -2.68B | 441M | -1.01B | -746M | -429M | -427M | -504M | -378M | -58M | -214M | -420M | 136M | -38M | 348M | -557M | -210M | -36M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | 598M | 886M | 2.53B | 491M | -742M | -165M | -215M | -66M | -3M | 133M | -80M | 481M | 327M | -7M | -150M | -383M | 153M | -134M | -59M | -109M | -561M | -370M | -175M | -167.7M | -101.7M | -85.5M | -120.9M | -73.5M | -1.6M | -11.8M | -8.6M |
| Change in Payables | -69M | 428M | 312M | -402M | 154M | -69M | 45M | 164M | -143M | 424M | -44M | -12M | 405M | -184M | 161M | -95M | 142M | 71M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -2.21B | -1.94B | -1.05B | -26.2B | -6.04B | 733M | -5.4B | 5.71B | 14.34B | -4.02B | -8.66B | -5.55B | -5.75B | -8.47B | -9.99B | -786M | -4.15B | -3.2B | -3.17B | -1.99B | -5.13B | -59M | -1.4B | -3.21B | -2.86B | -539.6M | -1.04B | -463.5M | -673.7M | -302.2M | -310.2M |
| Capital Expenditures | -2.16B | -1.86B | -1.1B | -1.11B | -936M | -880M | -608M | -618M | -738M | -664M | -837M | -649M | -1B | -693M | -689M | -567M | -580M | -530M | -672M | -1.27B | -1.22B | -867M | -1.34B | -1.36B | -658.5M | -441.8M | -437.7M | -304.2M | -407.8M | -387.8M | -266.9M |
| CapEx % of Revenue | 5.8% | 5.06% | 3.28% | 3.94% | 3.56% | 3.39% | 2.39% | 2.65% | 3.11% | 2.91% | 3.64% | 3% | 5% | 3.71% | 3.99% | 3.64% | 3.85% | 3.62% | 4.48% | 8.58% | 8.54% | 6.98% | 12.66% | 16.24% | 11.92% | 11% | 12.69% | 9.49% | 15.43% | 16.53% | 12.14% |
| Acquisitions | -53M | -53M | 0 | -26.99B | -3.73B | -2.69B | -3.22B | -13.62B | 195M | -19M | -21M | -359M | -165M | -9.43B | -2.39B | -701M | 0 | 0 | -56M | -697M | -2.17B | 0 | 0 | 0 | -1.9B | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | -32M | 50M | 225M | -12M | -35M | -75M | -52M | -145M | -148M | -123M | -118M | 398M | -590M | -36M | 45M | -97M | 51M | 128M | 24M | -210M | -33M | -8M | -242.5M | 246.8M | 28.4M | -27.7M | -10.1M | 14.1M | -38.3M | -119.2M |
| Cash from Financing | -5.32B | -10.86B | -9.41B | 21.05B | -4.04B | -8.27B | -4.87B | -15.77B | -22.49B | -6.59B | -2.6B | -3.12B | -2.88B | 2.73B | 419M | -674M | -1.23B | -2.02B | -3.07B | -2.67B | -815M | -4.54B | -1.61B | -1.37B | 1.78B | -478M | -502.7M | -682M | -405.8M | -530.9M | -409.8M |
| Debt Issued (Net) | -2.88B | -5.68B | -4.26B | 25.68B | 6.62B | 795M | 2.46B | -4.51B | -1.12B | 71M | 3.59B | 1.06B | -1.13B | 4.68B | 4.81B | 7.89B | 2.47B | 980M | -1.01B | 2.14B | -214M | -1.18B | 1.99B | -123M | 2.77B | 0 | 200K | -6.2M | 69.7M | 81.8M | -69.7M |
| Equity Issued (Net) | 0 | 0 | -200M | 0 | -6.36B | -4.97B | -3.49B | -7.7B | -17.79B | -3.16B | -2.96B | -2.27B | -363M | -832M | -4.61B | -8.31B | -3.79B | -3.04B | -2.11B | -4.82B | -698M | -3.34B | -3.62B | -1.27B | -992M | -459.8M | -466.2M | -775.9M | -566.6M | -548.9M | -287.9M |
| Dividends Paid | -3.85B | -5.12B | -4.83B | -4.56B | -4.2B | -4.01B | -3.75B | -3.51B | -3.51B | -3.37B | -3B | -2.4B | -1.85B | -1.42B | -1.12B | -500M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | -200M | 0 | -6.36B | -4.97B | -3.49B | -7.7B | -17.79B | -3.16B | -2.96B | -1.87B | -138M | -832M | -4.61B | -8.31B | -3.79B | -3.21B | -2.27B | -5.1B | -2B | -4.43B | -4.07B | -1.8B | -1.42B | -737.5M | -799.9M | -1.02B | -912.1M | -737.9M | -450M |
| Other Financing | 1.41B | -52M | -124M | -72M | -103M | -78M | -90M | -42M | -68M | -140M | -229M | -172M | 55M | 290M | 1.33B | 254M | 83M | 33M | 49M | 13M | 97M | -20M | 21M | 23M | 4.6M | -18.2M | -36.7M | 100.1M | 91.1M | -63.8M | -52.2M |
| Net Change in Cash | 3.23B | -2.84B | 1.03B | 3.31B | -360M | 1.72B | 229M | -908M | 3.15B | 559M | -903M | 413M | -74M | 548M | -3.69B | 3.66B | 403M | 1.11B | -250M | 741M | -557M | 314M | 689M | -1.02B | 1.16B | 462.6M | 95.6M | -70.2M | -38M | 69.8M | 102.6M |
| Free Cash Flow | 8.6B | 8.1B | 10.39B | 7.36B | 8.79B | 8.38B | 9.89B | 8.53B | 10.56B | 10.51B | 9.52B | 8.43B | 7.55B | 5.6B | 5.19B | 4.55B | 5.21B | 5.81B | 5.32B | 4.13B | 4.17B | 4.04B | 2.36B | 2.21B | 1.59B | 1.04B | 1.2B | 771.1M | 633.7M | 515.1M | 555.7M |
| FCF Margin % | 23.09% | 22.05% | 31.1% | 26.11% | 33.37% | 32.26% | 38.9% | 36.52% | 44.46% | 46.01% | 41.39% | 38.91% | 37.64% | 29.97% | 30.08% | 29.21% | 34.59% | 39.65% | 35.43% | 27.99% | 29.23% | 32.53% | 22.38% | 26.45% | 28.79% | 25.86% | 34.71% | 24.07% | 23.98% | 21.96% | 25.28% |
| FCF Growth % | -21.24% | -22.07% | 41.24% | -16.23% | 4.82% | -15.25% | 15.9% | -19.19% | 0.43% | 10.47% | 12.92% | 11.6% | 34.91% | 7.8% | 14.08% | -12.58% | -10.32% | 9.22% | 28.59% | -0.89% | 3.14% | 71.28% | 6.84% | 38.95% | 53.15% | -13.24% | 55.22% | 21.68% | 23.02% | -7.31% | -8.98% |
| FCF per Share | 15.80 | 14.94 | 19.21 | 13.68 | 16.24 | 14.63 | 16.76 | 14.01 | 15.88 | 14.30 | 12.62 | 11.00 | 9.81 | 7.32 | 6.60 | 4.99 | 5.40 | 5.69 | 4.95 | 3.68 | 3.51 | 3.21 | 1.79 | 1.64 | 1.38 | 0.96 | 1.10 | 0.72 | 0.60 | 0.47 | 0.49 |
| FCF Conversion (FCF/Net Income) | 1.10x | 1.29x | 2.81x | 1.26x | 1.48x | 1.57x | 1.45x | 1.17x | 1.35x | 5.65x | 1.34x | 1.31x | 1.66x | 1.24x | 1.35x | 1.39x | 1.25x | 1.38x | 1.43x | 1.71x | 1.83x | 1.34x | 1.56x | 1.58x | -1.62x | 1.32x | 1.44x | 0.98x | 1.21x | 1.40x | 1.21x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
IRA pricing negotiation exposure
As reported in financial statements, Amgen's operating cash flow to net income ratio has fluctuated wildly, reaching an extreme 7.61x in 2024Q4, which suggests that GAAP net income is currently a poor proxy for the company's underlying ability to generate actual cash from its core operations.
The significant divergence between net income and operating cash flow indicates that non-cash charges, particularly the amortization of intangibles from the Horizon acquisition, are heavily distorting reported profitability. Investors should monitor this gap closely, as it implies that the company's cash-generating capacity is far more resilient than the headline earnings figures suggest.
Based on the provided quarterly data, Amgen's free cash flow margins have exhibited high variance, ranging from a low of 3.5% in 2023Q4 to a peak of 48.4% in 2024Q4, highlighting the impact of lumpy acquisition-related outflows on the company's ability to sustain consistent cash generation.
The erratic FCF trajectory appears to be a direct consequence of the capital-intensive integration of the Horizon portfolio and the timing of milestone payments. This volatility warrants further investigation into whether the company can stabilize its cash conversion as the acquired assets move toward full operational synergy.
According to recent SEC filings, Amgen's capital expenditure as a percentage of revenue has trended upward, reaching 8.3% in 2026Q1, which indicates that the company is prioritizing investment in its specialized biomanufacturing infrastructure to maintain its competitive moat against emerging biosimilar and biologic entrants.
The rising capital intensity suggests that maintaining the company's proprietary manufacturing processes requires ongoing, significant reinvestment. This trend may indicate that Amgen is shifting toward a more asset-heavy model, which could pressure long-term free cash flow if revenue growth from new pipeline assets does not scale proportionally.
As evidenced by the quarterly cash flow data, working capital changes have been highly erratic, including a significant $2.1 billion inflow in 2024Q4 followed by a $1.9 billion outflow in 2025Q4, suggesting that inventory and receivables management remains sensitive to lumpy product distribution cycles.
These dramatic swings in working capital appear to be driven by the timing of large-scale product shipments and the integration of new rare disease assets. Analysts should interpret these fluctuations as a sign of operational complexity rather than a fundamental shift in the company's underlying cash collection efficiency.
Based on reported figures, Amgen's capital allocation has been dominated by the $27.8 billion acquisition in 2023Q4, which, when combined with consistent dividend payments, has placed significant pressure on the company's liquidity and necessitated a reliance on external financing to maintain its current shareholder return profile.
The company's decision to prioritize large-scale inorganic growth while maintaining dividends suggests a management focus on long-term portfolio transformation. However, the high debt load incurred from these acquisitions may limit future flexibility, particularly if regulatory headwinds like the IRA impact the cash flow available for debt service.
Quick answers to the most common questions about buying AMGN stock.
Amgen Inc. (AMGN) generated $9.96B in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Amgen Inc. (AMGN) generated $8.10B in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Amgen Inc. (AMGN) spent $1.86B on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Amgen Inc. (AMGN) returned $5.12B to shareholders via cash dividends. This shows the company's commitment to returning capital to its equity investors.