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ANAB logoAnaptysBio, Inc.(ANAB)Earnings, Financials & Key Ratios

ANAB•NASDAQ
$69.32
$2.99B mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutAnaptysBio, Inc., a clinical stage biotechnology company, engages in developing therapeutic product candidates for inflammation and immuno-oncology indications. Its products include Imsidolimab, an antibody that inhibits the interleukin-36 receptor (IL-36R) for the treatment of various dermatological inflammatory diseases; Rosnilimab, an anti-PD-1 agonist antibody program designed to augment PD-1 signaling through rosnilimab treatment to suppress T-cell driven human inflammatory diseases; and ANB032, an anti-BTLA modulator antibody applicable to human inflammatory diseases associated with lymphoid and myeloid immune cell dysregulation. The company also focuses on developing various antibody programs that are advanced to preclinical and clinical milestones under its collaborations. It has a collaboration and license agreement with GlaxoSmithKline, Inc. and Bristol-Myers Squibb; and license agreements with United Kingdom Research and Innovation, as well as Millipore Corporation. The company was formerly known as Anaptys Biosciences, Inc. and changed its name to AnaptysBio, Inc. in July 2006. AnaptysBio, Inc. was incorporated in 2005 and is based in San Diego, California.Show more
  • Revenue$235M+157.0%
  • EBITDA$50M+144.7%
  • Net Income-$13M+90.9%
  • EPS (Diluted)-0.46+91.0%
  • Gross Margin98.97%+224.5%
  • EBITDA Margin21.45%+117.4%
  • Operating Margin20.42%+116.2%
  • Net Margin-5.64%+96.5%
  • ROE-24.49%+86.6%
  • ROIC55.1%+223.7%
  • Debt/Equity0.38-92.7%
  • Interest Coverage0.60+131.6%
Technical→

ANAB Key Insights

AnaptysBio, Inc. (ANAB) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 98 (top 2%)
  • ✓Strong 5Y sales CAGR of 25.6%
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Shares diluted 10.4% in last year
  • ✗Expensive at 58.4x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

ANAB Price & Volume

AnaptysBio, Inc. (ANAB) stock price & volume — 10-year historical chart

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ANAB Growth Metrics

AnaptysBio, Inc. (ANAB) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years29.58%
5 Years25.62%
3 Years183.58%
TTM157.01%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM90.89%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM90.11%

Return on Capital

10 Years-14.53%
5 Years-15.48%
3 Years-15.77%
Last Year12.54%

ANAB Recent Earnings

AnaptysBio, Inc. (ANAB) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 10/12 qtrs (83%)●Beat Revenue 11/12 qtrs (92%)
Q2 2026Latest
Mar 3, 2026
EPS
$1.58
Est $0.89
+77.5%
Revenue
$108M
Est $87M
+24.4%
Q4 2025
Nov 4, 2025
EPS
$0.52
Est $1.06
+149.1%
Revenue
$76M
Est $22M
+248.2%
Q3 2025
Aug 7, 2025
EPS
$1.34
Est $1.50
+10.7%
Revenue
$22M
Est $12M
+90.5%
Q3 2025
Aug 6, 2025
EPS
$1.34
Est $1.50
+10.7%
Revenue
$22M
Est $21M
+6.9%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 3, 2026
$1.58vs $0.89+77.5%
$108Mvs $87M+24.4%
Q4 2025Nov 4, 2025
$0.52vs $1.06+149.1%
$76Mvs $22M+248.2%
Q3 2025Aug 7, 2025
$1.34vs $1.50+10.7%
$22Mvs $12M+90.5%
Q3 2025Aug 6, 2025
$1.34vs $1.50+10.7%
$22Mvs $21M+6.9%
Based on last 12 quarters of dataView full earnings history →

ANAB Peer Comparison

AnaptysBio, Inc. (ANAB) competitors in Immunology and Inflammation Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.62B26.06-7.92-4.26%-156.36%-68.97%0.16
ARQT logoARQTArcutis Biotherapeutics, Inc.Direct Competitor2.89B23.42-180.1591.34%-4.29%-8.52%0.03
DAWN logoDAWNDay One Biopharmaceuticals, Inc.Direct Competitor2.22B21.53-20.7020.6%-67.85%-23.43%0.01
FOLD logoFOLDAmicus Therapeutics, Inc.Direct Competitor4.47B14.49-80.5032.29%-2.35%-6.1%2.29
IMVT logoIMVTImmunovant, Inc.Direct Competitor5.66B27.84-10.20-47.07%0.00
REGN logoREGNRegeneron Pharmaceuticals, Inc.Product Competitor72.97B702.3316.930.99%29.65%14.32%5.59%0.09
ABBV logoABBVAbbVie Inc.Product Competitor364.63B206.1586.988.57%6.91%62.15%4.89%
LLY logoLLYEli Lilly and CompanyProduct Competitor933.66B988.1943.0644.7%34.98%101.17%0.96%1.60

Compare ANAB vs Peers

AnaptysBio, Inc. (ANAB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RCUS

Most directly comparable listed peer for ANAB.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ANAB against a more recognizable public peer.

Peer Set

Compare Top 5

vs RCUS, ARQT, DAWN, FOLD

ANAB Income Statement

AnaptysBio, Inc. (ANAB) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue10M5M8M75M63.17M10.29M17.16M91.28M234.6M
Revenue Growth %-40.06%-50%60%837.5%-15.77%-83.72%66.78%432.03%157.01%
Cost of Goods Sold29.44M56.2M99.34M80.03M98.5M88.8M132.28M163.84M2.42M
COGS % of Revenue294.43%1123.92%1241.72%106.7%155.91%863.21%771.01%179.49%1.03%
Gross Profit
-19.44M▲ 0%
-51.2M▼ 163.3%
-91.34M▼ 78.4%
-5.03M▲ 94.5%
-35.32M▼ 602.9%
-78.51M▼ 122.3%
-115.13M▼ 46.6%
-72.56M▲ 37.0%
232.18M▲ 420.0%
Gross Margin %-194.43%-1023.92%-1141.72%-6.7%-55.91%-763.21%-671.01%-79.49%98.97%
Gross Profit Growth %-1637%-163.31%-78.41%94.5%-602.91%-122.28%-46.64%36.97%419.98%
Operating Expenses9.34M15.53M16.09M18.85M21.49M36.64M49.28M42.39M184.28M
OpEx % of Revenue93.38%310.52%201.18%25.14%34.02%356.21%287.26%46.44%78.55%
Selling, General & Admin9.34M15.53M16.09M18.85M21.49M36.64M41.95M42.39M50.74M
SG&A % of Revenue93.38%310.52%201.18%25.14%34.02%356.21%244.48%46.44%21.63%
Research & Development30.94M56.3M99.34M80.03M98.5M88.8M139.62M163.84M135.97M
R&D % of Revenue309.43%1125.92%1241.72%106.7%155.91%863.21%813.79%179.49%57.96%
Other Operating Expenses-30.94M-56.3M-99.34M-80.03M-98.5M-88.8M-132.28M-163.84M-2.42M
Operating Income
-28.78M▲ 0%
-66.72M▼ 131.8%
-107.43M▼ 61.0%
-23.88M▲ 77.8%
-56.81M▼ 137.9%
-115.15M▼ 102.7%
-164.41M▼ 42.8%
-114.95M▲ 30.1%
47.9M▲ 141.7%
Operating Margin %-287.81%-1334.44%-1342.9%-31.84%-89.93%-1119.41%-958.27%-125.93%20.42%
Operating Income Growth %-851.44%-131.83%-61.01%77.77%-137.92%-102.69%-42.77%30.08%141.67%
EBITDA-28.6M-66.41M-106.92M-23.32M-54.72M-112.82M-163.76M-112.55M50.32M
EBITDA Margin %-285.98%-1328.14%-1336.48%-31.09%-86.62%-1096.71%-954.47%-123.3%21.45%
EBITDA Growth %-924.28%-132.21%-61%78.19%-134.67%-106.16%-45.15%31.27%144.71%
D&A (Non-Cash Add-back)183K315K514K559K2.09M2.33M652K2.4M2.42M
EBIT-28.3M-60.2M-96.45M-19.93M-57.8M-107.59M-157.07M-95.14M47.9M
Net Interest Income-152K5.03M9.94M3.96M-1.02M-13.56M790K-30.29M-66.39M
Interest Income1.62M6.68M10.98M3.96M431K7.55M18.87M19.79M13.5M
Interest Expense1.77M1.65M1.04M01.45M21.11M18.08M50.09M79.89M
Other Income/Expense-1.29M4.87M9.94M3.95M-982K-13.55M788K-30.28M-60.96M
Pretax Income
-30.07M▲ 0%
-61.85M▼ 105.7%
-97.49M▼ 57.6%
-19.93M▲ 79.6%
-57.8M▼ 190.0%
-128.7M▼ 122.7%
-163.62M▼ 27.1%
-145.23M▲ 11.2%
-13.07M▲ 91.0%
Pretax Margin %-300.7%-1236.96%-1218.6%-26.57%-91.49%-1251.09%-953.68%-159.1%-5.57%
Income Tax0-192K-152K0024K-4K3K164K
Effective Tax Rate %0%0.31%0.16%0%0%-0.02%0%-0%-1.25%
Net Income
-30.07M▲ 0%
-61.66M▼ 105.0%
-97.34M▼ 57.9%
-19.93M▲ 79.5%
-57.8M▼ 190.0%
-128.72M▼ 122.7%
-163.62M▼ 27.1%
-145.23M▲ 11.2%
-13.23M▲ 90.9%
Net Margin %-300.7%-1233.12%-1216.7%-26.57%-91.49%-1251.33%-953.66%-159.11%-5.64%
Net Income Growth %-606.03%-105.04%-57.87%79.52%-189.98%-122.72%-27.11%11.24%90.89%
Net Income (Continuing)-30.07M-61.66M-97.34M-19.93M-57.8M-128.72M-163.62M-145.23M-13.23M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-1.52▲ 0%
-2.50▼ 64.5%
-3.60▼ 44.0%
-0.73▲ 79.7%
-2.11▼ 189.0%
-4.57▼ 116.6%
-6.08▼ 33.0%
-5.12▲ 15.8%
-0.46▲ 91.0%
EPS Growth %-560.87%-64.47%-44%79.72%-189.04%-116.59%-33.04%15.79%91.02%
EPS (Basic)-1.52-2.50-3.60-0.73-2.11-4.57-6.08-5.12-0.46
Diluted Shares Outstanding19.78M24.67M27.06M27.3M27.43M28.16M26.92M28.38M31.34M
Basic Shares Outstanding19.78M24.67M27.06M27.3M27.43M28.16M26.92M28.38M27.79M
Dividend Payout Ratio---------

ANAB Balance Sheet

AnaptysBio, Inc. (ANAB) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets252.7M434.22M377.73M396.56M553.88M447.2M406.83M431.88M350.25M
Cash & Short-Term Investments248.41M427.08M374.23M393.65M548.1M441.24M390.9M385.37M311.64M
Cash Only81.19M113.6M171.02M250.46M495.73M71.31M35.97M123.08M238.2M
Short-Term Investments167.22M313.49M203.21M143.2M52.37M369.93M354.94M262.29M73.44M
Accounts Receivable1.6M174K00876K1.42M6.85M40.77M33.85M
Days Sales Outstanding58.4412.7--5.0650.35145.75163.0152.66
Inventory000000000
Days Inventory Outstanding---------
Other Current Assets000004.54M9.08M5.74M4.76M
Total Non-Current Assets76.67M74.78M57.46M19.99M89.19M163.18M45.55M51.96M14.14M
Property, Plant & Equipment665K1.45M1.62M2.13M21.84M19.99M18.27M16.23M13.89M
Fixed Asset Turnover15.04x3.46x4.94x35.26x2.89x0.51x0.94x5.62x16.89x
Goodwill000000000
Intangible Assets000000000
Long-Term Investments75.9M73.13M54.3M17.55M67.1M142.94M27.03M35.47M0
Other Non-Current Assets106K208K1.54M318K256K256K256K256K256K
Total Assets
329.36M▲ 0%
509M▲ 54.5%
435.2M▼ 14.5%
416.55M▼ 4.3%
643.07M▲ 54.4%
610.38M▼ 5.1%
452.39M▼ 25.9%
483.83M▲ 7.0%
364.39M▼ 24.7%
Asset Turnover0.03x0.01x0.02x0.18x0.10x0.02x0.04x0.19x0.64x
Asset Growth %429.69%54.54%-14.5%-4.28%54.38%-5.08%-25.88%6.95%-24.69%
Total Current Liabilities14.09M21.84M29.54M19.82M16.1M26.05M37.44M45.43M38.63M
Accounts Payable2.32M5.44M16.24M4.22M1.74M2.78M4.7M4M3.87M
Days Payables Outstanding28.835.3559.6619.236.4511.4412.968.92583.13
Short-Term Debt6.88M7.57M1.38M000002.08M
Deferred Revenue (Current)4.86M8.7M0000000
Other Current Liabilities1.59M2.42M2.15M3.69M4.18M5.38M23.77M39.5M32.67M
Current Ratio17.93x19.89x12.79x20.01x34.40x17.16x10.87x9.51x9.07x
Quick Ratio17.93x19.89x12.79x20.01x34.40x17.16x10.87x9.51x9.07x
Cash Conversion Cycle---------
Total Non-Current Liabilities7.69M796K654K0270.54M322.23M326.84M367.54M288.56M
Long-Term Debt7.55M625K00000353.43M12.03M
Capital Lease Obligations00654K019.45M17.81M16.04M14.11M0
Deferred Tax Liabilities-140K-171K0000000
Other Non-Current Liabilities140K171K00251.09M304.41M310.81M0276.53M
Total Liabilities21.78M22.63M30.19M19.82M286.64M348.28M364.29M412.97M327.19M
Total Debt14.45M8.26M2.9M342K20.95M19.45M17.81M369.46M14.11M
Net Debt-66.74M-105.34M-168.12M-250.11M-474.77M-51.86M-18.15M246.38M-224.08M
Debt / Equity0.05x0.02x0.01x0.00x0.06x0.07x0.20x5.21x0.38x
Debt / EBITDA--------0.28x
Net Debt / EBITDA---------4.45x
Interest Coverage-15.94x-36.44x-92.65x--39.86x-5.10x-8.69x-1.90x0.60x
Total Equity
307.58M▲ 0%
486.37M▲ 58.1%
405.01M▼ 16.7%
396.73M▼ 2.0%
356.43M▼ 10.2%
262.1M▼ 26.5%
88.1M▼ 66.4%
70.87M▼ 19.6%
37.21M▼ 47.5%
Equity Growth %683.29%58.13%-16.73%-2.04%-10.16%-26.46%-66.39%-19.56%-47.49%
Book Value per Share15.5519.7114.9714.5312.999.313.272.501.19
Total Shareholders' Equity307.58M486.37M405.01M396.73M356.43M262.1M88.1M70.87M37.21M
Common Stock24K27K27K27K28K29K27K30K28K
Retained Earnings-85.03M-146.69M-244.03M-263.96M-321.75M-450.48M-614.1M-759.33M-772.56M
Treasury Stock000000000
Accumulated OCI-426K-223K338K-4K-422K-5.25M-797K305K-24K
Minority Interest000000000

ANAB Cash Flow Statement

AnaptysBio, Inc. (ANAB) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-19.44M-48.51M-69.52M-14.16M-45.92M-73.59M-120.8M-135.34M19.7M
Operating CF Margin %-194.38%-970.12%-868.96%-18.88%-72.69%-715.4%-704.09%-148.27%8.4%
Operating CF Growth %-115.26%-149.54%-43.32%79.64%-224.36%-60.26%-64.15%-12.03%114.55%
Net Income-30.07M-61.66M-97.34M-19.93M-57.8M-128.72M-163.62M-145.23M49.61M
Depreciation & Amortization183K315K514K559K2.09M2.33M2.38M2.4M2.42M
Stock-Based Compensation4.38M9.96M12.41M11.5M15.35M27.36M33.2M34.05M36.07M
Deferred Taxes1.38M-1.23M0000000
Other Non-Cash Items619K646K-1.96M487K1.93M18.6M7.56M39.77M12.31M
Working Capital Changes4.08M3.46M16.85M-6.77M-7.49M6.84M-324K-66.33M-80.72M
Change in Receivables1.23M1.43M174K0-876K-543K0-33.91M6.92M
Change in Inventory-237.97M00000000
Change in Payables2.22M7.08M00-4.74M9.7M10.94M-33.84M-87.33M
Cash from Investing-243.06M-142.45M131.43M94.47M38.84M-394.85M144.75M95.4M228.03M
Capital Expenditures-290K-1.06M-805K-569K-1.37M-358K-807K-358K-87K
CapEx % of Revenue2.9%21.26%10.06%0.76%2.16%3.48%4.7%0.39%0.04%
Acquisitions290.9M347.54M000394.49M000
Investments---------
Other Investing-290.9M-347.54M0015K-394.49M000
Cash from Financing292.45M223.36M-4.49M-879K252.3M44.02M-59.3M127.05M-132.61M
Debt Issued (Net)0-6.88M-7.5M-1.38M00-11.73M34.77M-76.8M
Equity Issued (Net)292.54M227.48M3.01M496K2.55M11.83M-47.53M100.39M-54.37M
Dividends Paid000000000
Share Repurchases000000-50M-456K-68.63M
Other Financing-84K2.76M00249.75M32.19M-43K-8.1M-1.45M
Net Change in Cash
29.96M▲ 0%
32.41M▲ 8.2%
57.42M▲ 77.2%
79.44M▲ 38.3%
245.21M▲ 208.7%
-424.42M▼ 273.1%
-35.34M▲ 91.7%
87.11M▲ 346.5%
115.12M▲ 32.1%
Free Cash Flow
-19.73M▲ 0%
-49.57M▼ 151.3%
-70.32M▼ 41.9%
-14.73M▲ 79.1%
-47.29M▼ 221.1%
-73.95M▼ 56.4%
-121.61M▼ 64.4%
-135.69M▼ 11.6%
19.61M▲ 114.5%
FCF Margin %-197.28%-991.38%-879.03%-19.63%-74.85%-718.88%-708.79%-148.66%8.36%
FCF Growth %-117.27%-151.26%-41.87%79.06%-221.11%-56.39%-64.44%-11.58%114.45%
FCF per Share-1.00-2.01-2.60-0.54-1.72-2.63-4.52-4.780.63
FCF Conversion (FCF/Net Income)0.65x0.79x0.71x0.71x0.79x0.57x0.74x0.93x-1.49x
Interest Paid000000000
Taxes Paid000000000

ANAB Key Ratios

AnaptysBio, Inc. (ANAB) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-10.44%-17.34%-15.53%-21.84%-4.97%-15.35%-41.62%-93.44%-182.71%-24.49%
Return on Invested Capital (ROIC)--17.79%-16.09%-26.08%-9.34%-301.44%-187.96%-88.02%-44.53%55.1%
Gross Margin7.58%-194.43%-1023.92%-1141.72%-6.7%-55.91%-763.21%-671.01%-79.49%98.97%
Net Margin-25.53%-300.7%-1233.12%-1216.7%-26.57%-91.49%-1251.33%-953.66%-159.11%-5.64%
Debt / Equity0.35x0.05x0.02x0.01x0.00x0.06x0.07x0.20x5.21x0.38x
Interest Coverage-8.30x-15.94x-36.44x-92.65x--39.86x-5.10x-8.69x-1.90x0.60x
FCF Conversion2.12x0.65x0.79x0.71x0.71x0.79x0.57x0.74x0.93x-1.49x
Revenue Growth-5.05%-40.06%-50%60%837.5%-15.77%-83.72%66.78%432.03%157.01%

ANAB SEC Filings & Documents

AnaptysBio, Inc. (ANAB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 20, 2026·SEC

Material company update

Mar 27, 2026·SEC

Material company update

Mar 3, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 3, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Mar 11, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 4, 2025·SEC

FY 2025

Aug 6, 2025·SEC

FY 2025

May 5, 2025·SEC

ANAB Frequently Asked Questions

AnaptysBio, Inc. (ANAB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

AnaptysBio, Inc. (ANAB) reported $234.6M in revenue for fiscal year 2025. This represents a 4179% increase from $5.5M in 2013.

AnaptysBio, Inc. (ANAB) grew revenue by 157.0% over the past year. This is strong growth.

AnaptysBio, Inc. (ANAB) reported a net loss of $13.2M for fiscal year 2025.

Dividend & Returns

AnaptysBio, Inc. (ANAB) has a return on equity (ROE) of -24.5%. Negative ROE indicates the company is unprofitable.

AnaptysBio, Inc. (ANAB) generated $19.6M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

Explore More ANAB

AnaptysBio, Inc. (ANAB) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

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