Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in APGE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Venrock Adviser, LLC | 8.5M | $1.13B | 0.0% | 13.726% | 34.18% |
| 2 | BlackRock, Inc. | 5.5M | $730.9M | +34.8% | 8.900% | 0.01% |
| 3 | HBK INVESTMENTS L P | 2.9M | $378.3M | — | 4.606% | 1.84% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 2.6M | $341.4M | +2.8% | 4.157% | 0.01% |
| 5 | FMR LLC | 2.5M | $330.9M | -73.1% | 4.029% | 0.01% |
| 6 | STATE STREET CORP | 2.3M | $305.0M | +6.2% | 3.713% | 0.00% |
| 7 | BALYASNY ASSET MANAGEMENT L.P. | 2.2M | $287.4M | +393.6% | 3.499% | 0.36% |
| 8 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.7M | $231.0M | -9.4% | 2.812% | 1.34% |
| 9 | GOLDMAN SACHS GROUP INC | 1.7M | $224.8M | +159.5% | 2.737% | 0.02% |
| 10 | Paradigm Biocapital Advisors LP | 1.6M | $209.2M | +16.9% | 2.548% | 3.92% |
| 11 | VANGUARD PORTFOLIO MANAGEMENT LLC | 1.5M | $202.9M | +285.7% | 2.471% | 0.01% |
| 12 | MILLENNIUM MANAGEMENT LLC | 1.5M | $199.3M | +1521.6% | 2.427% | 0.07% |
| 13 | Pentwater Capital Management LP | 1.4M | $189.1M | — | 2.303% | 1.16% |
| 14 | MORGAN STANLEY | 1.4M | $188.7M | +138.9% | 2.298% | 0.01% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $174.6M | +8.0% | 2.125% | 0.01% |
| 16 | PERCEPTIVE ADVISORS LLC | 1.3M | $173.6M | -15.1% | 2.114% | 2.61% |
| 17 | Jupiter Topco LLC | 1.2M | $158.4M | — | 1.929% | 0.06% |
| 18 | BANK OF AMERICA CORP /DE/ | 1.1M | $149.5M | +25.0% | 1.820% | 0.01% |
| 19 | Affinity Asset Advisors, LLC | 987K | $131.0M | -23.2% | 1.595% | 5.92% |
| 20 | MERCER GLOBAL ADVISORS INC /ADV | 941K | $124.9M | +13.2% | 1.521% | 0.08% |
| 21 | First Light Asset Management, LLC | 930K | $123.5M | +61.3% | 1.503% | 7.50% |
| 22 | Kryger Capital LLC | 743K | $98.6M | — | 1.200% | 5.62% |
| 23 | Qube Research & Technologies Ltd | 660K | $87.6M | — | 1.066% | 0.08% |
| 24 | First Trust Capital Management L.P. | 625K | $83.0M | — | 1.010% | 4.83% |
| 25 | Remedium Capital Partners, LLC | 587K | $77.9M | +0.5% | 0.948% | 17.24% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in APGE — a direct measure of their conviction.
Filings activity in APGE during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new APGE position in Q2 2026
Institutions that fully closed their APGE position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 291 | +27% | 111.46% | 19.06 pp | $8.73B | +51% |
| Q1 2026 | 229 | +9.0% | 130.52% | +7.60 pp | $5.77B | +17% |
| Q4 2025 | 210 | +22% | 122.92% | 0.26 pp | $4.95B | +111% |
| Q3 2025 | 172 | 3.9% | 123.18% | +2.41 pp | $2.35B | 4.6% |
| Q2 2025 | 179 | +6.5% | 120.77% | 30.46 pp | $2.46B | +8.2% |
| Q1 2025 | 168 | +7.7% | 151.23% | +29.91 pp | $2.27B | 11% |
| Q4 2024 | 156 | +12% | 121.32% | +1.16 pp | $2.55B | 21% |
| Q3 2024 | 139 | — | 120.16% | — | $3.23B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying APGE stock.
Based on Q2 2026 13F filings, institutional ownership of Apogee Therapeutics, Inc. stands at 111.5%, held across 291 reporting institutions.
Venrock Adviser, LLC is the largest reported institutional holder of APGE, with approximately 8,493,321 shares worth $1.13B as of Q2 2026.
Yes — 1 widely-followed marquee investor appear among the top 25 institutional holders of APGE, including MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for APGE is 49 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
112 institutions opened new positions in APGE during Q2 2026, while 48 fully exited. 127 added to existing positions and 47 trimmed.
APGE institutional ownership fell by 19.06 percentage points quarter-over-quarter, with a net change of +62 holders.
The top 10 institutions account for 47.7% of all reported 13F value in APGE, and the top 25 account for 72.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.