Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in APLS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 13.5M | $544.6M | +116.2% | 10.574% | 0.01% |
| 2 | Avoro Capital Advisors LLC | 12.2M | $491.7M | 0.0% | 9.547% | 5.03% |
| 3 | MORGAN STANLEY | 10.0M | $404.0M | +9.5% | 7.844% | 0.02% |
| 4 | STATE STREET CORP | 6.8M | $275.4M | +48.4% | 5.347% | 0.01% |
| 5 | UBS Group AG | 6.2M | $249.7M | +48.3% | 4.848% | 0.04% |
| 6 | VANGUARD PORTFOLIO MANAGEMENT LLC | 5.4M | $217.4M | β | 4.222% | 0.01% |
| 7 | Pentwater Capital Management LP | 5.3M | $211.2M | β | 4.101% | 1.10% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 4.8M | $191.9M | β | 3.725% | 0.00% |
| 9 | Deep Track Capital, LP | 4.5M | $182.3M | -41.5% | 3.540% | 3.76% |
| 10 | Point72 Asset Management, L.P. | 4.2M | $168.3M | +600.0% | 3.268% | 0.24% |
| 11 | RTW INVESTMENTS, LP | 3.7M | $148.2M | -51.9% | 2.879% | 1.48% |
| 12 | HBK INVESTMENTS L P | 3.5M | $142.8M | β | 2.773% | 1.86% |
| 13 | SUVRETTA CAPITAL MANAGEMENT, LLC | 3.5M | $141.5M | -15.0% | 2.748% | 3.84% |
| 14 | MILLENNIUM MANAGEMENT LLC | 2.3M | $91.1M | +139.4% | 1.770% | 0.06% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 2.1M | $83.5M | +2.4% | 1.621% | 0.01% |
| 16 | GOLDMAN SACHS GROUP INC | 2.0M | $79.7M | +946.6% | 1.547% | 0.01% |
| 17 | BALYASNY ASSET MANAGEMENT LLC | 1.9M | $77.1M | +935.7% | 1.498% | 0.26% |
| 18 | DIMENSIONAL FUND ADVISORS LP | 1.3M | $53.7M | +640.1% | 1.046% | 0.01% |
| 19 | TIG Advisors, LLC | 1.3M | $50.4M | β | 0.979% | 2.59% |
| 20 | TORONTO DOMINION BANK | 1.2M | $49.7M | β | 0.966% | 0.07% |
| 21 | HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND | 1.2M | $48.4M | β | 0.939% | 0.08% |
| 22 | BANK OF AMERICA CORP /DE/ | 1.2M | $47.9M | +24.5% | 0.930% | 0.00% |
| 23 | Hudson Bay Capital Management LP | 1.2M | $47.9M | +0.9% | 0.930% | 0.52% |
| 24 | FIL Ltd | 1.1M | $45.9M | β | 0.890% | 0.04% |
| 25 | Kryger Capital LLC | 1.1M | $44.3M | β | 0.859% | 3.13% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in APLS β a direct measure of their conviction.
Filings activity in APLS during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 315 | +14% | 103.83% | +34.11 pp | $5.45B | +49% |
| Q4 2025 | 277 | +4.1% | 69.72% | +16.42 pp | $3.66B | +31% |
| Q3 2025 | 266 | +9.0% | 53.30% | +10.31 pp | $2.80B | +24% |
| Q2 2025 | 244 | 1.6% | 42.99% | 8.09 pp | $2.26B | 16% |
| Q1 2025 | 248 | 2.4% | 51.08% | 25.52 pp | $2.68B | 33% |
| Q4 2024 | 254 | +1.2% | 76.60% | +14.11 pp | $4.02B | +23% |
| Q3 2024 | 251 | 1.6% | 62.49% | 17.01 pp | $3.28B | 21% |
| Q2 2024 | 255 | β | 79.50% | β | $4.18B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying APLS stock.
Based on Q1 2026 13F filings, institutional ownership of Apellis Pharmaceuticals, Inc. stands at 103.8%, held across 315 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of APLS, with approximately 13,536,964 shares worth $0.54B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of APLS, including Point72 Asset Management, L.P., MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for APLS is 72 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
122 institutions opened new positions in APLS during Q1 2026, while 84 fully exited. 145 added to existing positions and 45 trimmed.
APLS institutional ownership rose by 34.11 percentage points quarter-over-quarter, with a net change of +38 holders.
The top 10 institutions account for 53.8% of all reported 13F value in APLS, and the top 25 account for 75.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Apellis Pharmaceuticals, Inc. (APLS) Institutional Ownership