Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ASMB held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | GILEAD SCIENCES, INC. | 4.5M | $125.0M | 0.0% | 28.349% | 5.90% |
| 2 | FARALLON CAPITAL MANAGEMENT LLC | 1.2M | $34.1M | 0.0% | 7.724% | 0.22% |
| 3 | RA CAPITAL MANAGEMENT, L.P. | 1.0M | $28.3M | 0.0% | 6.421% | 0.30% |
| 4 | COMMODORE CAPITAL LP | 1.0M | $27.8M | 0.0% | 6.292% | 1.61% |
| 5 | JANUS HENDERSON GROUP PLC | 849K | $23.5M | +1.4% | 5.344% | 0.01% |
| 6 | Paradigm Biocapital Advisors LP | 665K | $18.5M | 0.0% | 4.186% | 0.38% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 490K | $13.6M | — | 3.086% | 0.00% |
| 8 | Parkman Healthcare Partners LLC | 411K | $11.4M | +64.9% | 2.587% | 1.18% |
| 9 | Point72 Asset Management, L.P. | 344K | $9.5M | -42.7% | 2.165% | 0.01% |
| 10 | Blackstone Inc | 297K | $8.2M | -6.9% | 1.868% | 0.03% |
| 11 | MILLENNIUM MANAGEMENT LLC | 234K | $6.5M | +137.9% | 1.470% | 0.00% |
| 12 | BlackRock, Inc. | 203K | $5.6M | +5.4% | 1.276% | 0.00% |
| 13 | STEMPOINT CAPITAL LP | 185K | $5.1M | +18.3% | 1.167% | 1.36% |
| 14 | B Group, Inc. | 176K | $4.9M | 0.0% | 1.106% | 3.61% |
| 15 | MARSHALL WACE, LLP | 163K | $4.5M | +26.6% | 1.028% | 0.00% |
| 16 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 161K | $4.5M | 0.0% | 1.013% | 0.01% |
| 17 | Patient Square Capital LP | 136K | $3.8M | +7.3% | 0.858% | 0.67% |
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 133K | $3.7M | +1.3% | 0.837% | 0.00% |
| 19 | Schonfeld Strategic Advisors LLC | 121K | $3.3M | +122.2% | 0.758% | 0.02% |
| 20 | Caption Management, LLC | 82K | $2.3M | -23.2% | 0.515% | 0.02% |
| 21 | HighVista Strategies LLC | 75K | $2.1M | — | 0.470% | 0.57% |
| 22 | VANGUARD FIDUCIARY TRUST CO | 72K | $2.0M | — | 0.451% | 0.00% |
| 23 | Qube Research & Technologies Ltd | 69K | $1.9M | +64.2% | 0.436% | 0.00% |
| 24 | STATE STREET CORP | 57K | $1.6M | +7.0% | 0.357% | 0.00% |
| 25 | Seven Fleet Capital Management LP | 56K | $1.6M | +1201.2% | 0.353% | 0.49% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in ASMB — a direct measure of their conviction.
Filings activity in ASMB during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 73 | +5.8% | 102.42% | 25.43 pp | $374M | 20% |
| Q4 2025 | 69 | +21% | 127.85% | +38.39 pp | $467M | +43% |
| Q3 2025 | 57 | +63% | 89.46% | +74.01 pp | $326M | +479% |
| Q2 2025 | 35 | 7.9% | 15.45% | +7.20 pp | $56M | +87% |
| Q1 2025 | 38 | +5.6% | 8.25% | 5.44 pp | $30M | 40% |
| Q4 2024 | 36 | +16% | 13.69% | +9.50 pp | $50M | +227% |
| Q3 2024 | 31 | +15% | 4.19% | 0.12 pp | $15M | 2.7% |
| Q2 2024 | 27 | — | 4.31% | — | $16M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ASMB stock.
Based on Q1 2026 13F filings, institutional ownership of Assembly Biosciences, Inc. stands at 102.4%, held across 73 reporting institutions.
GILEAD SCIENCES, INC. is the largest reported institutional holder of ASMB, with approximately 4,505,391 shares worth $0.13B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of ASMB, including Point72 Asset Management, L.P., MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for ASMB is 47 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
16 institutions opened new positions in ASMB during Q1 2026, while 12 fully exited. 15 added to existing positions and 42 trimmed.
ASMB institutional ownership fell by 25.43 percentage points quarter-over-quarter, with a net change of +4 holders.
The top 10 institutions account for 80.3% of all reported 13F value in ASMB, and the top 25 account for 94.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Assembly Biosciences, Inc. (ASMB) Institutional Ownership