Assembly Biosciences, Inc. (ASMB) P/E Ratio History
Deep ValueTrading at -41.0x · 0th percentile of 5-year range · Significant discount to historical valuation · Data 2026–2026
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P/E Ratio Analysis
As of October 3, 2026, Assembly Biosciences, Inc. (ASMB) trades at a price-to-earnings ratio of -41.0x, with a stock price of $22.54 and trailing twelve-month earnings per share of $-0.00.
The current P/E is 182% below its 5-year average of 50.0x. Over the past five years, ASMB's P/E has ranged from a low of 50.0x to a high of 50.0x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 23.2x, ASMB trades at a 277% discount to its sector peers. The sector includes 225 companies with P/E ratios ranging from 0.0x to 190.0x.
Relative to the broader market, ASMB trades at a notable discount to the S&P 500 median P/E of 24.5x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our ASMB DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
ASMB Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
ASMB P/E vs Peers
Vaccines and Infectious Disease peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $180B | 21.3 | 0.16Best | +1684% | |
| $76B | 17.7Lowest | 2.80 | +8% | |
| $29B | 94.3 | - | +207% | |
| $128B | 32.9 | 3.98 | +837% | |
| $23B | 18.0 | - | +4173%Best | |
| $356B | 19.8 | 0.93 | +8% | |
| $464B | 110.9 | - | -1% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
ASMB Historical P/E Data (2026–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q2 | - | $27.48 | $0.55 | 50.0x | +0% |
Average P/E for displayed period: 50.0x
ASMB Chart Terminal
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Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
Peer Comparison
Compare growth, multiples, and margins vs sector.
ASMB — Frequently Asked Questions
Quick answers to the most common questions about buying ASMB stock.
What is ASMB's P/E ratio?
Assembly Biosciences, Inc. (ASMB) trailing twelve-month P/E ratio is -41.0x, based on TTM diluted EPS of $-0.00. The 5-year average P/E is 50.0x and the historical range spans 50.0x to 50.0x.
Is ASMB stock overvalued or undervalued?
ASMB trades at -41.0x P/E, below its 5-year average of 50.0x. At the 0th percentile of its historical range (50.0x–50.0x), the stock is priced at a discount to its own history.
Is ASMB stock expensive?
No, ASMB is not expensive on a historical basis. The current P/E of -41.0x is below the 5-year average of 50.0x and sits at the 0th percentile of its valuation range.
What is ASMB's historical P/E range?
Over the past 5 years, ASMB's P/E ratio has ranged from 50.0x to 50.0x, with a median of 50.0x and an average of 50.0x. The current P/E of -41.0x places the stock at the 0th percentile of this range. Full historical data spans 2026–2026.
How does ASMB's P/E compare to the S&P 500?
ASMB trades at -41.0x P/E versus the S&P 500 median of 24.5x. The 267% discount to the market suggests lower growth expectations or perceived higher risk.
How does ASMB's valuation compare to Healthcare peers?
Assembly Biosciences, Inc. P/E of -41.0x compares to the Healthcare sector median of 23.2x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is ASMB's PEG ratio?
ASMB PEG ratio is N/A, based on a P/E of -41.0x and EPS growth of 91.8%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is ASMB's earnings yield?
ASMB earnings yield is N/A, the inverse of its -41.0x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.