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CDXS logoCodexis, Inc.(CDXS)Earnings, Financials & Key Ratios

CDXS•NASDAQ
$2.66
$242M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryLife Science Tools and Reagents
AboutCodexis, Inc. discovers, develops, and sells enzymes and other proteins. It offers biocatalyst products and services; intermediate chemicals products that are used for further chemical processing; and Codex biocatalyst panels and kits that enable customers to perform chemistry screening. The company also provides biocatalyst screening and protein engineering services. In addition, it offers CodeEvolver protein engineering technology platform, which helps in developing and delivering biocatalysts that perform chemical transformations and enhance the efficiency and productivity of manufacturing processes. The company's platform is also used to discover novel biotherapeutic drug candidates for targeted human diseases, as well as for molecular biology and in vitro diagnostic enzymes. It sells its products to pharmaceutical manufacturers through its direct sales and business development force in the United States and Europe. The company was incorporated in 2002 and is headquartered in Redwood City, California.Show more
  • Revenue$70M+18.6%
  • EBITDA-$30M+48.8%
  • Net Income-$44M+32.6%
  • EPS (Diluted)-0.50+43.8%
  • Gross Margin79.49%+9.6%
  • EBITDA Margin-42.68%+56.8%
  • Operating Margin-54.46%+44.8%
  • Net Margin-62.47%+43.2%
  • ROE-74.88%+11.9%
  • ROIC-31.85%+47.4%
  • Debt/Equity1.45+61.9%
  • Interest Coverage-7.96
Technical→

CDXS Key Insights

Codexis, Inc. (CDXS) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 94 (top 6%)

✗Weaknesses

  • ✗Profits declining 12.9% over 5 years
  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Shares diluted 18.7% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CDXS Price & Volume

Codexis, Inc. (CDXS) stock price & volume — 10-year historical chart

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CDXS Growth Metrics

Codexis, Inc. (CDXS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years5.35%
5 Years0.38%
3 Years-20.22%
TTM18.61%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM32.63%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM42.22%

Return on Capital

10 Years-32.89%
5 Years-31.14%
3 Years-42.59%
Last Year-30.93%

CDXS Recent Earnings

Codexis, Inc. (CDXS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 5/12 qtrs (42%)
Q2 2026Latest
Mar 11, 2026
EPS
$0.11
Est $0.01
+1000.0%
Revenue
$39M
Est $36M
+8.6%
Q4 2025
Nov 6, 2025
EPS
$0.22
Est $0.15
-46.7%
Revenue
$9M
Est $36M
-76.0%
Q3 2025
Aug 13, 2025
EPS
$0.16
Est $0.17
+5.9%
Revenue
$15M
Est $19M
-21.3%
Q2 2025
May 14, 2025
EPS
$0.25
Est $0.20
-25.0%
Revenue
$8M
Est $10M
-21.9%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 11, 2026
$0.11vs $0.01+1000.0%
$39Mvs $36M+8.6%
Q4 2025Nov 6, 2025
$0.22vs $0.15-46.7%
$9Mvs $36M-76.0%
Q3 2025Aug 13, 2025
$0.16vs $0.17+5.9%
$15Mvs $19M-21.3%
Q2 2025May 14, 2025
$0.25vs $0.20-25.0%
$8Mvs $10M-21.9%
Based on last 12 quarters of dataView full earnings history →

CDXS Peer Comparison

Codexis, Inc. (CDXS) competitors in Life Science Tools and Reagents — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
GEVO logoGEVOGevo, Inc.Direct Competitor497.05M2.05-14.648.49%0.75%0.25%0.01
BEAM logoBEAMBeam Therapeutics Inc.Direct Competitor3.32B32.33-39.92120.01%-57.24%-7.31%0.24
TRMK logoTRMKTrustmark CorporationDirect Competitor2.64B44.9212.1434.75%10.77%0.53
NUVB logoNUVBNuvation Bio Inc.Product Competitor1.75B5.04-8.406.99%-102.06%-44.1%0.03
RCKT logoRCKTRocket Pharmaceuticals, Inc.Product Competitor418.11M3.86-1.92-80.49%0.09
CRBU logoCRBUCaribou Biosciences, Inc.Product Competitor182.26M1.95-1.23-100%-16.9%-80.77%0.22
NTLA logoNTLAIntellia Therapeutics, Inc.Product Competitor1.61B13.85-3.64-100%-61.47%0.14
MRK logoMRKMerck & Co., Inc.Supply Chain280.48B113.5615.601.18%28.12%36.14%0.96

Compare CDXS vs Peers

Codexis, Inc. (CDXS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs GEVO

Most directly comparable listed peer for CDXS.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CDXS against a more recognizable public peer.

Peer Set

Compare Top 5

vs GEVO, BEAM, TRMK, NUVB

CDXS Income Statement

Codexis, Inc. (CDXS) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue50.02M60.59M68.46M69.06M104.75M138.59M70.14M59.34M70.39M
Revenue Growth %2.43%21.13%12.98%0.87%51.69%32.3%-49.39%-15.39%18.61%
Cost of Goods Sold14.33M12.62M15.63M13.74M22.21M38.03M12.81M16.29M14.44M
COGS % of Revenue28.64%20.83%22.83%19.9%21.2%27.44%18.26%27.45%20.51%
Gross Profit
35.7M▲ 0%
47.97M▲ 34.4%
52.83M▲ 10.1%
55.31M▲ 4.7%
82.55M▲ 49.2%
100.56M▲ 21.8%
57.33M▼ 43.0%
43.06M▼ 24.9%
55.95M▲ 29.9%
Gross Margin %71.36%79.17%77.17%80.1%78.8%72.56%81.74%72.55%79.49%
Gross Profit Growth %-8.67%34.39%10.11%4.71%49.23%21.82%-42.98%-24.9%29.95%
Operating Expenses58.67M59.27M65.38M79.23M105.24M135.44M125.4M101.58M94.28M
OpEx % of Revenue117.28%97.81%95.5%114.74%100.47%97.73%178.78%171.16%133.95%
Selling, General & Admin29.01M29.29M31.5M35.05M49.32M52.17M53.25M55.15M47.07M
SG&A % of Revenue57.99%48.34%46.02%50.75%47.08%37.64%75.92%92.93%66.88%
Research & Development29.66M29.98M33.87M44.19M55.92M80.1M58.88M46.26M44.36M
R&D % of Revenue59.29%49.47%49.48%63.98%53.38%57.8%83.95%77.96%63.02%
Other Operating Expenses-92K-291K0003.17M13.27M165K2.85M
Operating Income
-22.97M▲ 0%
-11.29M▲ 50.8%
-12.55M▼ 11.1%
-23.92M▼ 90.6%
-22.7M▲ 5.1%
-34.88M▼ 53.7%
-68.07M▼ 95.1%
-58.52M▲ 14.0%
-38.33M▲ 34.5%
Operating Margin %-45.92%-18.64%-18.33%-34.64%-21.67%-25.17%-97.04%-98.61%-54.46%
Operating Income Growth %-168.22%50.83%-11.1%-90.61%5.11%-53.68%-95.15%14.03%34.5%
EBITDA-21.93M-10.15M-7.99M-19.37M-16.75M-29.48M-62.55M-58.68M-30.04M
EBITDA Margin %-43.84%-16.75%-11.67%-28.04%-15.99%-21.27%-89.18%-98.89%-42.68%
EBITDA Growth %-445.74%53.72%21.25%-142.32%13.51%-75.99%-112.19%6.18%48.81%
D&A (Non-Cash Add-back)1.04M1.15M4.56M4.55M5.95M5.4M5.52M-165K8.29M
EBIT-22.97M-11.29M-12.55M-23.92M-22.7M-31.71M-54.8M-58.35M-38.33M
Net Interest Income147K671K1.29M405K459K1.44M4.17M3.67M-2.19M
Interest Income147K671K1.29M405K459K1.44M4.17M3.67M2.63M
Interest Expense000000004.81M
Other Income/Expense55K380K631K249K1.61M1.56M-8.1M-6.72M-5.59M
Pretax Income
-22.91M▲ 0%
-10.91M▲ 52.4%
-11.92M▼ 9.2%
-23.67M▼ 98.6%
-21.09M▲ 10.9%
-33.32M▼ 58.0%
-76.17M▼ 128.6%
-65.24M▲ 14.3%
-43.93M▲ 32.7%
Pretax Margin %-45.81%-18.01%-17.41%-34.28%-20.13%-24.04%-108.59%-109.94%-62.41%
Income Tax81K-37K17K339K189K276K69K34K47K
Effective Tax Rate %-0.35%0.34%-0.14%-1.43%-0.9%-0.83%-0.09%-0.05%-0.11%
Net Income
-23M▲ 0%
-10.88M▲ 52.7%
-11.94M▼ 9.7%
-24.01M▼ 101.2%
-21.28M▲ 11.4%
-33.59M▼ 57.9%
-76.24M▼ 127.0%
-65.28M▲ 14.4%
-43.97M▲ 32.6%
Net Margin %-45.97%-17.95%-17.43%-34.77%-20.31%-24.24%-108.69%-109.99%-62.47%
Net Income Growth %-168.71%52.7%-9.72%-101.17%11.37%-57.86%-126.96%14.38%32.63%
Net Income (Continuing)-23M-10.88M-11.94M-24.01M-21.28M-33.59M-76.24M-65.28M-43.97M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)
-0.50▲ 0%
-0.21▲ 58.0%
-0.21▲ 0.0%
-0.40▼ 90.5%
-0.33▲ 17.5%
-0.51▼ 54.5%
-1.12▼ 119.6%
-0.89▲ 20.5%
-0.50▲ 43.8%
EPS Growth %-138.1%58%0%-90.48%17.5%-54.55%-119.61%20.54%43.82%
EPS (Basic)-0.50-0.21-0.21-0.40-0.33-0.51-1.12-0.89-0.50
Diluted Shares Outstanding46.23M52.2M56.52M59.36M64.57M65.34M68.13M73.41M87.14M
Basic Shares Outstanding46.23M52.2M56.52M59.36M64.57M65.34M68.13M73.41M87.14M
Dividend Payout Ratio---------

CDXS Balance Sheet

Codexis, Inc. (CDXS) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets45.04M67.2M114.2M184.42M161.89M162.89M93.47M98.77M96.82M
Cash & Short-Term Investments31.22M53.04M90.5M150.12M116.8M113.98M65.12M73.46M78.21M
Cash Only31.22M53.04M90.5M149.12M116.8M113.98M65.12M19.26M50.79M
Short-Term Investments0001M00054.19M27.42M
Accounts Receivable11.8M13.5M20.16M29.29M37.65M40.87M19.93M18.88M10.73M
Days Sales Outstanding86.181.33107.46154.8131.19107.65103.7116.1555.64
Inventory1.04M589K371K964K1.16M2.03M2.69M1.8M1.82M
Days Inventory Outstanding26.3917.048.6625.619.0619.4776.5140.3145.94
Other Current Assets984K0661K638K579K521K5.74M4.63M6.06M
Total Non-Current Assets8.59M11.09M34.87M37.22M84.5M87.5M43.09M50.24M50.98M
Property, Plant & Equipment2.81M4.76M30.39M31.18M65.46M61.88M28.62M42.9M43.52M
Fixed Asset Turnover17.77x12.73x2.25x2.22x1.60x2.24x2.45x1.38x1.62x
Goodwill3.24M3.24M3.24M3.24M3.24M3.24M2.46M2.46M2.46M
Intangible Assets000000000
Long-Term Investments671K588K01.45M14M20.51M9.7M2.8M2.5M
Other Non-Current Assets1.86M2.5M1.24M1.36M1.79M1.87M2.31M2.08M2.5M
Total Assets
53.63M▲ 0%
78.28M▲ 46.0%
149.07M▲ 90.4%
221.65M▲ 48.7%
246.38M▲ 11.2%
250.39M▲ 1.6%
136.56M▼ 45.5%
149.01M▲ 9.1%
147.8M▼ 0.8%
Asset Turnover0.93x0.77x0.46x0.31x0.43x0.55x0.51x0.40x0.48x
Asset Growth %50.43%45.98%90.43%48.68%11.16%1.63%-45.46%9.12%-0.81%
Total Current Liabilities24.95M17.11M15.39M24.98M33.37M49.07M35.83M23.65M25.32M
Accounts Payable3.54M3.05M2.62M2.97M3M3.25M5.95M2.84M1.55M
Days Payables Outstanding90.3188.2161.278.8949.2231.15169.4663.639.29
Short-Term Debt000000000
Deferred Revenue (Current)12.29M3.94M57K1.82M2.59M13.73M10.12M350K7.01M
Other Current Liabilities4.36M5.8M5M10.27M11.12M11.45M11.25M11.41M13.81M
Current Ratio1.81x3.93x7.42x7.38x4.85x3.32x2.61x4.18x3.82x
Quick Ratio1.76x3.89x7.40x7.34x4.82x3.28x2.53x4.10x3.75x
Cash Conversion Cycle22.1810.1554.92101.52101.0495.9710.7592.8662.29
Total Non-Current Liabilities4.13M4.86M28.17M26.56M48.62M56.53M14.12M58.44M71.95M
Long-Term Debt000000028.91M40.1M
Capital Lease Obligations302K61K24.95M22.32M43.56M38.28M12.24M28.16M30.16M
Deferred Tax Liabilities000000000
Other Non-Current Liabilities2.32M1.45M1.23M1.27M1.31M1.37M1.23M1.27M1.33M
Total Liabilities29.08M21.98M43.56M51.54M81.99M105.6M49.95M82.08M97.27M
Total Debt302K61K26.12M24.95M47.65M43.64M16.02M59.9M73.21M
Net Debt-30.92M-52.98M-64.38M-124.17M-69.14M-70.35M-49.09M40.63M22.41M
Debt / Equity0.01x0.00x0.25x0.15x0.29x0.30x0.19x0.89x1.45x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage---------7.96x
Total Equity
24.55M▲ 0%
56.31M▲ 129.4%
105.52M▲ 87.4%
170.1M▲ 61.2%
164.39M▼ 3.4%
144.8M▼ 11.9%
86.61M▼ 40.2%
66.93M▼ 22.7%
50.53M▼ 24.5%
Equity Growth %28.53%129.38%87.4%61.21%-3.36%-11.92%-40.18%-22.73%-24.5%
Book Value per Share0.531.081.872.872.552.221.270.910.58
Total Shareholders' Equity24.55M56.31M105.52M170.1M164.39M144.8M86.61M66.93M50.53M
Common Stock5K5K6K6K6K6K7K8K9K
Retained Earnings-315.06M-330.47M-342.41M-366.42M-387.7M-421.29M-497.53M-562.81M-606.78M
Treasury Stock000000000
Accumulated OCI-472K00000052K8K
Minority Interest000000000

CDXS Cash Flow Statement

Codexis, Inc. (CDXS) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-8.76M-14.09M-12.56M-16.46M-14.27M11.28M-52.64M-49.41M-19.38M
Operating CF Margin %-17.52%-23.26%-18.35%-23.84%-13.62%8.14%-75.04%-83.26%-27.53%
Operating CF Growth %-224.44%-60.84%10.88%-31.08%13.34%179.09%-566.48%6.13%60.79%
Net Income-23M-10.88M-11.94M-24.01M-21.28M-33.59M-76.24M-65.28M-43.97M
Depreciation & Amortization1.04M1.15M4.56M4.55M5.95M10.25M9.92M4.95M5.25M
Stock-Based Compensation7.09M7.89M6.94M7.73M11.59M14.53M9.97M13.09M9.62M
Deferred Taxes9K00-900K-2.88M0000
Other Non-Cash Items-207K91K525K55K-19K-1.48M21.93M9.85M3.31M
Working Capital Changes6.3M-12.34M-12.65M-3.89M-7.62M21.57M-18.22M-12.02M6.42M
Change in Receivables-5.65M960K2.52M-12.32M-15.57M-3.23M20.25M1.25M8.51M
Change in Inventory-210K447K217K-593K-196K-869K-656K886K-19K
Change in Payables-801K-524K-428K101K268K207K2.29M-2.57M-1.29M
Cash from Investing-908K-2.77M-3.67M-5.75M-21.42M-13.58M-4.86M-56.98M23.5M
Capital Expenditures-985K-2.77M-3.73M-3.75M-13.83M-8.31M-4.42M-4.3M-4.47M
CapEx % of Revenue1.97%4.57%5.45%5.43%13.2%5.99%6.3%7.25%6.35%
Acquisitions2K2K3K036K29K751K87K5K
Investments---------
Other Investing77K2K3K036K29K-440K00
Cash from Financing21.65M38.57M53.96M80.81M3.77M-575K8.17M60.52M27.93M
Debt Issued (Net)-175K-238K-242K-60K00029.52M9.89M
Equity Issued (Net)23.78M37.5M50M86.25M4.97M913K8.65M31.32M18.03M
Dividends Paid000000000
Share Repurchases000000000
Other Financing-1.96M1.31M4.2M-5.38M-1.21M-1.49M-485K-318K0
Net Change in Cash
11.98M▲ 0%
21.71M▲ 81.2%
37.74M▲ 73.8%
58.6M▲ 55.3%
-31.92M▼ 154.5%
-2.87M▲ 91.0%
-49.33M▼ 1619.4%
-45.87M▲ 7.0%
32.05M▲ 169.9%
Free Cash Flow
-9.75M▲ 0%
-16.86M▼ 73.0%
-16.29M▲ 3.4%
-20.21M▼ 24.1%
-28.09M▼ 39.0%
2.98M▲ 110.6%
-57.06M▼ 2016.6%
-53.72M▲ 5.9%
-23.85M▲ 55.6%
FCF Margin %-19.49%-27.83%-23.8%-29.27%-26.82%2.15%-81.34%-90.51%-33.88%
FCF Growth %-171.61%-72.98%3.39%-24.08%-39%110.6%-2016.56%5.86%55.6%
FCF per Share-0.21-0.32-0.29-0.34-0.440.05-0.84-0.73-0.27
FCF Conversion (FCF/Net Income)0.38x1.30x1.05x0.69x0.67x-0.34x0.69x0.76x0.44x
Interest Paid141K84K49K52K14K34K44K2.57M0
Taxes Paid32K5K5K312K102K100K194K17K0

CDXS Key Ratios

Codexis, Inc. (CDXS) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-40.77%-105.38%-26.91%-14.75%-17.42%-12.72%-21.73%-65.89%-85.03%-74.88%
Return on Invested Capital (ROIC)-4078.1%--254.54%-42.33%-41.21%-24.11%-30.83%-91.19%-60.5%-31.85%
Gross Margin80.03%71.36%79.17%77.17%80.1%78.8%72.56%81.74%72.55%79.49%
Net Margin-17.52%-45.97%-17.95%-17.43%-34.77%-20.31%-24.24%-108.69%-109.99%-62.47%
Debt / Equity0.02x0.01x0.00x0.25x0.15x0.29x0.30x0.19x0.89x1.45x
Interest Coverage----------7.96x
FCF Conversion0.32x0.38x1.30x1.05x0.69x0.67x-0.34x0.69x0.76x0.44x
Revenue Growth16.82%2.43%21.13%12.98%0.87%51.69%32.3%-49.39%-15.39%18.61%

CDXS SEC Filings & Documents

Codexis, Inc. (CDXS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 14, 2026·SEC

Material company update

Mar 11, 2026·SEC

Material company update

Nov 6, 2025·SEC

10-K Annual Reports

4
FY 2026

Mar 11, 2026·SEC

FY 2025

Feb 27, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 13, 2025·SEC

FY 2025

May 14, 2025·SEC

CDXS Frequently Asked Questions

Codexis, Inc. (CDXS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Codexis, Inc. (CDXS) reported $70.4M in revenue for fiscal year 2025. This represents a 480% increase from $12.1M in 2006.

Codexis, Inc. (CDXS) grew revenue by 18.6% over the past year. This is strong growth.

Codexis, Inc. (CDXS) reported a net loss of $44.0M for fiscal year 2025.

Dividend & Returns

Codexis, Inc. (CDXS) has a return on equity (ROE) of -74.9%. Negative ROE indicates the company is unprofitable.

Codexis, Inc. (CDXS) had negative free cash flow of $23.8M in fiscal year 2025, likely due to heavy capital investments.

Explore More CDXS

Codexis, Inc. (CDXS) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

→

Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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