Last 47 quarters of trend data · Healthcare · Life Science Tools
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -3.20 | — | — | 3.70 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | 193.83 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 1.50 | 3.45 | 2.43 | 0.95 | 6.40 | 3.40 | 7.35 | 4.52 | 4.32 | 6.84 | 3.57 | 2.00 | 3.54 | 2.22 | 5.26 | 2.51 | 2.88 | 4.45 | 9.50 | 20.71 | 10.71 |
| — | +1.5% | -67.0% | -78.9% | +48.1% | -50.3% | +105.8% | +126.4% | +22.2% | +208.1% | -32.1% | -20.7% | +23.0% | -50.1% | -44.6% | -87.9% | -73.2% | -69.0% | -53.5% | +32.0% | +13.6% | |
| P/B Ratio | 1.86 | 6.24 | 3.42 | 2.93 | 5.71 | 3.75 | 4.47 | 5.79 | 3.02 | 3.55 | 3.08 | 2.45 | 1.43 | 1.52 | 2.17 | 2.11 | 2.57 | 4.28 | 8.46 | 12.35 | 9.32 |
| — | +66.7% | -23.4% | -49.4% | +89.0% | +5.5% | +45.2% | +136.8% | +110.7% | +132.9% | +42.0% | +16.0% | -44.2% | -64.4% | -74.4% | -82.9% | -72.4% | -52.3% | -5.9% | +59.1% | +22.1% | |
| P/FCF | — | — | — | 1.89 | — | — | — | — | — | — | — | — | — | — | — | 15.43 | 5.38 | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | 2.63 | — | — | — | — | — | — | — | 18.06 | — | — | — | — | — | — | — | — | 133.57 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | 4.43 | — | — | — | — | — | — | — | 144.91 | — | — | — | — | — | — | — | — | 278.10 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 86.7% | 76.5% | 78.3% | 91.4% | 71.3% | 77.8% | 63.8% | 83.0% | 66.4% | 56.6% | 64.2% | 84.6% | 75.8% | 85.1% | 65.2% | 72.2% | 71.6% | 70.7% | 75.9% | 72.2% | 81.3% |
| — | -1.8% | +22.7% | +10.1% | +7.5% | +37.5% | -0.7% | -2.0% | -12.4% | -33.5% | -1.4% | +17.3% | +5.8% | +20.4% | -14.1% | -0.1% | -11.9% | -14.9% | -0.9% | +0.1% | +1.4% | |
| Operating Margin | -54.5% | -75.3% | -52.7% | 35.9% | -220.3% | -83.9% | -271.6% | -34.2% | -129.0% | -284.9% | -69.6% | 1.1% | -345.6% | -59.2% | -182.3% | -43.6% | -30.9% | -6.8% | -23.7% | -42.4% | 3.6% |
| — | +10.3% | +80.6% | +204.9% | -70.8% | +70.5% | -290.0% | -3333.6% | +62.7% | -381.1% | +61.8% | +102.4% | -1020.0% | -771.7% | -668.2% | -2.9% | -953.0% | +61.5% | +53.3% | -127.2% | +111.0% | |
| Net Margin | -62.5% | -80.5% | -57.1% | 24.7% | -228.1% | -86.6% | -274.3% | -48.4% | -160.8% | -285.2% | -67.4% | -27.1% | -376.3% | -54.0% | -174.2% | -41.5% | -29.0% | -6.9% | -23.6% | -41.6% | 6.1% |
| — | +7.0% | +79.2% | +151.0% | -41.8% | +69.6% | -307.0% | -78.6% | +57.3% | -427.7% | +61.3% | +34.7% | -1198.1% | -686.2% | -636.8% | +0.2% | -575.0% | +59.0% | +53.0% | -123.2% | +118.4% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -74.9% | -31.5% | -18.6% | 21.6% | -41.7% | -25.2% | -35.5% | -14.8% | -30.6% | -32.3% | -13.9% | -8.1% | -32.4% | -9.2% | -16.7% | -8.4% | -6.4% | -1.7% | -5.2% | -6.1% | 1.4% |
| — | -25.0% | +47.7% | +245.8% | -36.1% | +22.0% | -155.9% | -83.1% | +5.4% | -251.0% | +17.0% | +4.2% | -408.1% | -455.0% | -222.9% | -38.0% | -571.2% | +36.5% | +4.8% | -103.4% | +120.6% | |
| ROA | -29.6% | -9.6% | -6.3% | 7.1% | -15.0% | -9.9% | -14.9% | -7.0% | -14.7% | -16.2% | -8.0% | -4.9% | -19.3% | -5.4% | -9.7% | -5.2% | -4.2% | -1.1% | -3.5% | -4.3% | 1.0% |
| — | +3.1% | +57.8% | +201.2% | -1.6% | +38.5% | -85.1% | -41.3% | +23.8% | -198.0% | +16.7% | +4.8% | -354.8% | -383.1% | -178.3% | -20.7% | -516.5% | +44.1% | +17.0% | -97.3% | +123.4% | |
| ROIC | -31.9% | -10.7% | -7.9% | 13.6% | -15.9% | -10.2% | -15.5% | -5.9% | -15.2% | -22.8% | -17.5% | 0.6% | -43.7% | -13.7% | -25.4% | -12.1% | -7.8% | -1.7% | -6.1% | -9.3% | 1.5% |
| — | -4.6% | +48.8% | +328.6% | -4.2% | +55.1% | +11.4% | -1149.1% | +65.2% | -66.5% | +31.0% | +104.7% | -464.1% | -693.2% | -317.1% | -30.2% | -604.4% | +73.0% | +58.3% | -42.9% | +115.2% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 1.45 | 2.20 | 1.69 | 1.45 | 1.78 | 1.24 | 1.20 | 0.89 | 0.57 | 0.69 | 0.55 | 0.19 | 0.22 | 0.33 | 0.34 | 0.30 | 0.29 | 0.29 | 0.30 | 0.29 | 0.14 |
| — | +77.6% | +40.7% | +61.9% | +212.3% | +79.1% | +119.9% | +383.7% | +161.1% | +109.6% | +62.3% | -38.6% | -25.0% | +14.2% | +12.7% | +4.0% | +114.0% | +98.9% | +100.7% | +97.6% | -51.7% | |
| Debt / EBITDA | — | — | — | 4.52 | — | — | — | — | — | — | — | 7.11 | — | — | — | — | — | — | — | — | 8.31 |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 3.82 | 3.06 | 5.36 | 3.82 | 4.12 | 5.82 | 3.72 | 4.18 | 3.21 | 2.99 | 3.71 | 2.61 | 2.68 | 3.36 | 3.39 | 3.32 | 4.58 | 4.84 | 4.91 | 4.85 | 5.20 |
| — | -47.5% | +44.1% | -8.4% | +28.3% | +94.6% | +0.3% | +60.1% | +19.9% | -10.9% | +9.4% | -21.4% | -41.4% | -30.6% | -30.9% | -31.6% | -12.0% | -32.4% | -36.2% | -34.3% | +3.6% | |
| Quick Ratio | 3.75 | 2.99 | 5.23 | 3.75 | 4.02 | 5.70 | 3.64 | 4.10 | 3.15 | 2.92 | 3.63 | 2.53 | 2.62 | 3.30 | 3.34 | 3.28 | 4.52 | 4.78 | 4.86 | 4.82 | 5.17 |
| — | -47.5% | +43.8% | -8.5% | +27.4% | +95.1% | +0.3% | +61.8% | +20.3% | -11.6% | +8.6% | -22.7% | -42.1% | -31.0% | -31.3% | -31.9% | -12.4% | -32.7% | -36.5% | -34.4% | +3.6% | |
| Interest Coverage | -8.13 | — | — | — | -14.18 | — | -20.95 | -1.62 | -3.19 | -22.09 | — | — | — | -1278.33 | — | — | — | — | — | — | — |
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Includes 30+ ratios · 47 years · Updated daily
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Quick answers to the most common questions about buying CDXS stock.
Codexis, Inc.'s current P/E is -3.2x. The average P/E over the last 1 quarters is 3.7x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Codexis, Inc.'s current operating margin is -54.5%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Codexis, Inc.'s business trajectory between earnings reports.