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CLSD logoClearside Biomedical, Inc.(CLSD)Earnings, Financials & Key Ratios

CLSD•NASDAQ
$0.41
$2M mkt cap·Price updated May 1, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOphthalmology Therapies and Delivery
AboutClearside Biomedical, Inc., a biopharmaceutical company, focuses on the revolutionizing the delivery of therapies to the back of the eye through the suprachoroidal space. The company offers XIPERE, a triamcinolone acetonide suprachoroidal injectable suspension for the treatment of uveitis macular edema. It also develops CLS-AX, an axitinib injectable suspension for suprachoroidal injection, which is in Phase 1/2a clinical trial; and CLS-301, an integrin inhibitor suspension for the treatment of diabetic macular edema and macular degeneration. The company has a collaboration with Bausch Health, Arctic Vision, REGENXBIO, Inc., and Aura Biosciences. Clearside Biomedical, Inc. was incorporated in 2011 and is headquartered in Alpharetta, Georgia.Show more
  • Revenue$2M-79.8%
  • EBITDA-$29M-15.7%
  • Net Income-$34M-5.7%
  • EPS (Diluted)-7.05+11.3%
  • Gross Margin91.05%-4.8%
  • EBITDA Margin-1722.12%-471.7%
  • Operating Margin-1735.7%-474.7%
  • Net Margin-2064.42%-422.8%
  • Interest Coverage-2.95-11.3%
Technical→

CLSD Key Insights

Clearside Biomedical, Inc. (CLSD) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 2 (bottom 2%)
  • ✗Sales declining 5.2% over 5 years
  • ✗Shares diluted 19.4% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CLSD Price & Volume

Clearside Biomedical, Inc. (CLSD) stock price & volume — 10-year historical chart

Loading chart...

CLSD Growth Metrics

Clearside Biomedical, Inc. (CLSD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-5.2%
3 Years-61.68%
TTM-56.78%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM18.45%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM23.94%

Return on Capital

10 Years-111.15%
5 Years-81.36%
3 Years-87.37%
Last Year-121.51%

CLSD Peer Comparison

Clearside Biomedical, Inc. (CLSD) competitors in Ophthalmology Therapies and Delivery — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
OCUL logoOCULOcular Therapeutix, Inc.Direct Competitor2.12B9.68-6.82-18.67%-5.58%-64.55%0.12
ADVM logoADVMAdverum Biotechnologies, Inc.Direct Competitor96.26M4.36-0.66-72.22%-189.84%1.30
RCKT logoRCKTRocket Pharmaceuticals, Inc.Direct Competitor397.53M3.67-1.83-80.49%0.09
REPL logoREPLReplimune Group, Inc.Direct Competitor265.97M3.34-1.09-149.55%0.18
NVCR logoNVCRNovoCure LimitedDirect Competitor1.92B16.83-13.808.28%-25.66%-50.82%0.85
AGIO logoAGIOAgios Pharmaceuticals, Inc.Product Competitor1.64B27.53-3.8748.03%-6.4%-34.11%0.05
PRAX logoPRAXPraxis Precision Medicines, Inc.Product Competitor9.63B333.28-24.72-100%-43.02%0.00
ALDX logoALDXAldeyra Therapeutics, Inc.Product Competitor104.08M1.73-1.84-87.71%0.22

Compare CLSD vs Peers

Clearside Biomedical, Inc. (CLSD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs OCUL

Most directly comparable listed peer for CLSD.

Scale Benchmark

vs ISRG

Larger-name benchmark to compare CLSD against a more recognizable public peer.

Peer Set

Compare Top 5

vs OCUL, ADVM, RCKT, REPL

CLSD Income Statement

Clearside Biomedical, Inc. (CLSD) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue520K345K30K2.17M7.89M29.57M1.33M8.23M1.66M3.33M
Revenue Growth %--33.65%-91.3%7143.33%263.28%274.65%-95.51%519.89%-79.77%-56.78%
Cost of Goods Sold000000204K355K149K481K
COGS % of Revenue------15.37%4.32%8.95%-
Gross Profit
520K▲ 0%
345K▼ 33.7%
30K▼ 91.3%
2.17M▲ 7143.3%
7.89M▲ 263.3%
29.57M▲ 274.7%
1.12M▼ 96.2%
7.87M▲ 600.9%
1.51M▼ 80.8%
2.85M▲ 0%
Gross Margin %100%100%100%100%100%100%84.63%95.68%91.05%85.55%
Gross Profit Growth %1675.76%-33.65%-91.3%7143.33%263.28%274.65%-96.2%600.89%-80.75%-
Operating Expenses25.72M58.75M82.97M32.48M25.83M30.2M31.4M32.72M30.4M25.81M
OpEx % of Revenue4945.77%17029.86%276583.33%1494.57%327.2%102.12%2366.24%397.7%1826.74%-
Selling, General & Admin6.26M9.7M14.68M16.82M10.76M11.66M11.77M11.87M11.81M12.67M
SG&A % of Revenue1204.42%2811.59%48946.67%774%136.26%39.44%886.96%144.29%709.56%-
Research & Development19.45M49.05M68.29M15.66M15.07M18.54M19.63M20.85M18.59M13.22M
R&D % of Revenue3741.35%14218.26%227636.67%720.57%190.94%62.68%1479.28%253.42%1117.19%-
Other Operating Expenses0-567K127K000000-84K
Operating Income
-25.2M▲ 0%
-58.41M▼ 131.8%
-82.94M▼ 42.0%
-30.3M▲ 63.5%
-17.93M▲ 40.8%
-627K▲ 96.5%
-30.28M▼ 4728.9%
-24.84M▲ 17.9%
-28.88M▼ 16.3%
-22.96M▲ 0%
Operating Margin %-4845.77%-16929.86%-276483.33%-1394.57%-227.2%-2.12%-2281.61%-302.02%-1735.7%-689.76%
Operating Income Growth %-45.51%-131.8%-42.01%63.46%40.82%96.5%-4728.87%17.94%-16.25%-
EBITDA-25.13M-58.23M-82.76M-30.09M-17.75M-449K-30.13M-24.78M-28.66M-22.63M
EBITDA Margin %-4833.27%-16877.1%-275853.33%-1384.86%-224.92%-1.52%-2270.69%-301.2%-1722.12%-679.78%
EBITDA Growth %-45.64%-131.67%-42.13%63.64%41%97.47%-6610.91%17.77%-15.66%7.56%
D&A (Non-Cash Add-back)65K182K189K211K180K178K145K67K226K332K
EBIT-25.2M-58.41M-82.94M-30.3M-17.88M376K-29.61M-23.13M-24.57M-14.7M
Net Interest Income000000-2.67M-7.64M-8.32M-9.88M
Interest Income0001.03M335K0669K1.72M1.46M701K
Interest Expense0001.03M335K03.34M9.36M9.78M10.58M
Other Income/Expense-684K-567K127K-466K-275K1M-2.67M-7.64M-5.47M-2.32M
Pretax Income
-25.88M▲ 0%
-58.98M▼ 127.9%
-82.82M▼ 40.4%
-30.77M▲ 62.8%
-18.21M▲ 40.8%
376K▲ 102.1%
-32.95M▼ 8862.5%
-32.48M▲ 1.4%
-34.35M▼ 5.7%
-25.28M▲ 0%
Pretax Margin %-4977.31%-17094.2%-276060%-1416.01%-230.68%1.27%-2482.82%-394.91%-2064.42%-759.42%
Income Tax-65K-182K127K000000715K
Effective Tax Rate %0.25%0.31%-0.15%0%0%0%0%0%0%-2.83%
Net Income
-25.88M▲ 0%
-58.98M▼ 127.9%
-82.82M▼ 40.4%
-30.77M▲ 62.8%
-18.21M▲ 40.8%
376K▲ 102.1%
-32.95M▼ 8862.5%
-32.48M▲ 1.4%
-34.35M▼ 5.7%
-26M▲ 0%
Net Margin %-4977.31%-17094.2%-276060%-1416.01%-230.68%1.27%-2482.82%-394.91%-2064.42%-780.9%
Net Income Growth %-46.73%-127.86%-40.43%62.85%40.82%102.06%-8862.5%1.4%-5.75%18.45%
Net Income (Continuing)-25.88M-58.98M-82.82M-30.77M-18.21M376K-32.95M-32.48M-34.35M-26M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-29.55▲ 0%
-34.95▼ 18.3%
-40.35▼ 15.5%
-12.00▲ 70.3%
-5.85▲ 51.3%
0.09▲ 101.6%
-8.25▼ 8830.2%
-7.95▲ 3.6%
-7.05▲ 11.3%
-4.97▲ 0%
EPS Growth %-36.81%-18.27%-15.45%70.26%51.25%101.62%-8830.16%3.64%11.32%23.94%
EPS (Basic)-29.55-34.95-40.35-12.00-5.850.10-8.25-7.95-7.05-
Diluted Shares Outstanding874.07K1.69M2.05M2.54M3.1M3.99M4.01M4.12M4.92M5.23M
Basic Shares Outstanding874.07K1.69M2.05M2.54M3.1M3.9M4.01M4.12M4.92M5.23M
Dividend Payout Ratio----------

CLSD Balance Sheet

Clearside Biomedical, Inc. (CLSD) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets83.63M37.64M42.94M25.22M18.12M42.14M49.4M30.12M21.27M8.25M
Cash & Short-Term Investments83.63M37.64M40.88M22.59M17.29M30.44M48.42M28.92M20.02M6.8M
Cash Only34.82M9.22M8.04M22.59M17.29M30.44M48.42M28.92M20.02M6.8M
Short-Term Investments48.81M28.42M32.84M0000000
Accounts Receivable0000010M0170K507K266K
Days Sales Outstanding-----123.42-7.54111.2185.71
Inventory00000921K0000
Days Inventory Outstanding----------
Other Current Assets290K116K17K1.49M109K779K279K311K13K0
Total Non-Current Assets360K360K1.18M1.56M1.2M767K1.9M3.89M3.85M3.39M
Property, Plant & Equipment94K885K790K1.2M944K607K1.87M3.87M3.82M3.36M
Fixed Asset Turnover5.53x0.39x0.04x1.82x8.36x48.72x0.71x2.13x0.44x0.93x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments360K360K360K0260K030K000
Other Non-Current Assets-94K-885K26K360K0160K030K30K120K
Total Assets
84.81M▲ 0%
40.49M▼ 52.3%
44.12M▲ 9.0%
26.78M▼ 39.3%
19.32M▼ 27.8%
42.9M▲ 122.0%
51.3M▲ 19.6%
34.02M▼ 33.7%
25.13M▼ 26.1%
11.64M▲ 0%
Asset Turnover0.01x0.01x0.00x0.08x0.41x0.69x0.03x0.24x0.07x0.19x
Asset Growth %302.82%-52.26%8.96%-39.31%-27.84%122.04%19.58%-33.69%-26.14%-192.04%
Total Current Liabilities5.41M13.52M10.48M10.9M9.94M4.64M5.78M6.81M4.79M2.77M
Accounts Payable2.59M5.38M6.87M1.28M2M941K1.05M2.21M1.45M796K
Days Payables Outstanding------1.88K2.27K3.56K1K
Short-Term Debt03.2M556K1.33M991K0349K364K00
Deferred Revenue (Current)160K140K05M5M0205K75K00
Other Current Liabilities23K219K1.86M2.28M1.13M02.34M2.31M00
Current Ratio15.46x2.78x4.10x2.31x1.82x9.08x8.54x4.42x4.44x4.44x
Quick Ratio15.46x2.78x4.10x2.31x1.82x8.88x8.54x4.42x4.44x4.44x
Cash Conversion Cycle----------918.04
Total Non-Current Liabilities7.59M8.01M10.02M4.72M616K288K34.91M43.12M59.19M62.82M
Long-Term Debt7.59M4.81M9.42M3.82M0033.98M41.99M51.77M0
Capital Lease Obligations000897K616K288K936K649K328K783K
Deferred Tax Liabilities-320K-750K00000000
Other Non-Current Liabilities0610K605K0000480K7.09M137.6M
Total Liabilities13.15M19.08M20.5M15.62M10.56M4.93M40.7M49.93M63.98M65.59M
Total Debt7.59M8.01M9.97M6.41M1.98M675K35.26M43M52.47M446K
Net Debt-27.24M-1.22M1.93M-16.19M-15.31M-29.76M-13.16M14.08M32.45M-6.36M
Debt / Equity0.11x0.37x0.42x0.57x0.23x0.02x3.32x---0.01x
Debt / EBITDA----------0.02x
Net Debt / EBITDA---------0.28x
Interest Coverage----29.31x-53.54x--9.07x-2.65x-2.95x-1.39x
Total Equity
71.66M▲ 0%
21.41M▼ 70.1%
23.62M▲ 10.3%
11.16M▼ 52.8%
8.76M▼ 21.5%
37.98M▲ 333.4%
10.61M▼ 72.1%
-15.91M▼ 250.0%
-38.85M▼ 144.2%
-53.95M▲ 0%
Equity Growth %295.47%-70.12%10.3%-52.76%-21.46%333.36%-72.07%-250.01%-144.19%-382.06%
Book Value per Share81.9812.6911.534.382.839.512.64-3.86-7.90-10.31
Total Shareholders' Equity71.66M21.41M23.62M11.16M8.76M37.98M10.61M-15.91M-38.85M-53.95M
Common Stock25K25K32K44K52K60K61K63K77K78K
Retained Earnings-65.25M-124.22M-206.89M-237.66M-255.87M-255.49M-288.44M-320.92M-355.27M-373.96M
Treasury Stock0000000000
Accumulated OCI-13K-8K00000000
Minority Interest0000000000

CLSD Cash Flow Statement

Clearside Biomedical, Inc. (CLSD) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-22.71M-51.08M-79.2M-27.07M-13.12M-10.73M-13.37M-18.14M-24.7M-24.7M
Operating CF Margin %-4367.12%-14806.67%-264000%-1245.65%-166.2%-36.29%-1007.16%-220.46%-1484.25%-
Operating CF Growth %-63.35%-124.95%-55.04%65.82%51.53%18.19%-24.52%-35.69%-36.19%-1111.61%
Net Income-25.88M-58.98M-82.82M-30.77M-18.21M376K-32.95M-32.48M-34.35M-26M
Depreciation & Amortization65K182K189K211K180K178K145K67K226K332K
Stock-Based Compensation1.31M3.36M4.79M4.61M3.6M5.05M4.88M4.2M4.51M3.33M
Deferred Taxes65K181K-748K-52K000000
Other Non-Cash Items439K211K266K230K188K-998K3.32M9.36M6.59M2.97M
Working Capital Changes1.29M3.95M-874K-1.3M1.12M-15.34M11.24M720K-1.68M-1.92M
Change in Receivables00001.89M-10.87M10.42M-220K-51K0
Change in Inventory00000-681K0000
Change in Payables1.42M4.71M-314K-5.58M0681K694K614K-1.43M-2.34M
Cash from Investing-49.14M20.12M-3.76M32.92M-55K0-246K-1.78M-638K9.3M
Capital Expenditures-3K-306K-88K-25K-55K0-246K-1.78M-977K-453K
CapEx % of Revenue0.58%88.7%293.33%1.15%0.7%-18.54%21.6%58.71%-
Acquisitions0-20.12M-660K0000000
Investments----------
Other Investing-360K20.12M660K0000000
Cash from Financing86.39M5.36M81.78M8.7M7.87M23.78M31.33M414K16.44M4.91M
Debt Issued (Net)1.53M01.7M-5M-4.35M030.64M00961K
Equity Issued (Net)1000K1000K1000K1000K1000K1000K695K1000K1000K2M
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing31K305K515K52K258K499K0-1.25M47K418K
Net Change in Cash
14.54M▲ 0%
-25.6M▼ 276.1%
-1.18M▲ 95.4%
14.55M▲ 1332.2%
-5.31M▼ 136.5%
13.05M▲ 345.8%
17.88M▲ 37.0%
-19.5M▼ 209.0%
-8.9M▲ 54.4%
-7.09M▲ 0%
Free Cash Flow
-22.71M▲ 0%
-51.39M▼ 126.3%
-79.29M▼ 54.3%
-27.09M▲ 65.8%
-13.18M▲ 51.4%
-10.73M▲ 18.5%
-13.61M▼ 26.8%
-19.91M▼ 46.3%
-25.68M▼ 28.9%
-21.74M▲ 0%
FCF Margin %-4367.69%-14895.36%-264293.33%-1246.8%-166.9%-36.29%-1025.7%-242.06%-1542.97%-652.96%
FCF Growth %-63%-126.26%-54.29%65.83%51.37%18.54%-26.81%-46.29%-28.94%-10.89%
FCF per Share-25.98-30.45-38.70-10.65-4.25-2.69-3.39-4.83-5.22-5.22
FCF Conversion (FCF/Net Income)0.88x0.87x0.96x0.88x0.72x-28.55x0.41x0.56x0.72x0.84x
Interest Paid0000524K00000
Taxes Paid0000000000

CLSD Key Ratios

Clearside Biomedical, Inc. (CLSD) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-147.9%-126.73%-367.79%-176.96%-182.83%1.61%-135.63%--55.47%
Return on Invested Capital (ROIC)-42.54%-135.58%-271.94%-221.49%--56.32%-801.69%--53.08%
Gross Margin100%100%100%100%100%100%84.63%95.68%91.05%85.55%
Net Margin-4977.31%-17094.2%-276060%-1416.01%-230.68%1.27%-2482.82%-394.91%-2064.42%-780.9%
Debt / Equity0.11x0.37x0.42x0.57x0.23x0.02x3.32x---0.01x
Interest Coverage----29.31x-53.54x--9.07x-2.65x-2.95x-1.39x
FCF Conversion0.88x0.87x0.96x0.88x0.72x-28.55x0.41x0.56x0.72x0.84x
Revenue Growth--33.65%-91.3%7143.33%263.28%274.65%-95.51%519.89%-79.77%-56.78%

CLSD Frequently Asked Questions

Clearside Biomedical, Inc. (CLSD) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Clearside Biomedical, Inc. (CLSD) reported $3.3M in revenue for fiscal year 2024.

Clearside Biomedical, Inc. (CLSD) saw revenue decline by 79.8% over the past year.

Clearside Biomedical, Inc. (CLSD) reported a net loss of $26.0M for fiscal year 2024.

Dividend & Returns

Clearside Biomedical, Inc. (CLSD) had negative free cash flow of $21.7M in fiscal year 2024, likely due to heavy capital investments.

Explore More CLSD

Clearside Biomedical, Inc. (CLSD) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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