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COYACoya Therapeutics, Inc.
$5.50$100M
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COYA logoCoya Therapeutics, Inc.(COYA)Earnings, Financials & Key Ratios

COYA•NASDAQ
$5.50
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCell and Gene Therapy Developers
AboutCoya Therapeutics, Inc., a clinical-stage biotechnology company, develops proprietary medicinal products to modulate the function of regulatory T cells (Tregs). The company's product candidate pipeline is based on therapeutic modalities, such as Treg-enhancing biologics, Treg-derived exosomes, and autologous Treg cell therapy. It is developing COYA 101, an autologous regulatory T-cell product candidate that has completed Phase 2a clinical trial for use in the treatment of Amyotrophic Lateral Sclerosis. The company's product candidates in IND-enabling studies include COYA 301, a Treg-enhancing biologic for use in the treatment of Frontotemporal Dementia; and COYA 302, a biologic combination for subcutaneous and/or intravenous administration intended to enhance Treg function while depleting T effector function and activated macrophages for use in the treatment of neurodegenerative and autoimmune diseases. It is also developing COYA 201, an allogeneic Treg exosome product candidate that is in preclinical stage for use in the treatment of neurodegenerative, autoimmune, and metabolic diseases; and COYA 206, an antigen directed Treg-derived exosome product candidate, which is in discovery stage. The company was incorporated in 2020 and is headquartered in Houston, Texas.Show more
  • Revenue$8M+123.6%
  • EBITDA-$20M-17.5%
  • Net Income-$21M-42.6%
  • EPS (Diluted)-1.27-29.6%
  • Gross Margin99.66%+142.6%
  • EBITDA Margin-254.71%+47.4%
  • Operating Margin-255.05%+47.5%
  • Net Margin-267.14%+36.2%
  • ROE-51.39%-29.9%

COYA Price & Volume

Coya Therapeutics, Inc. (COYA) stock price & volume — 10-year historical chart

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Milestone Dependency Masks Underlying Clinical Burn Rate

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Mixed
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical Trial Execution Failure
"Coya Therapeutics operates as a research-intensive biotechnology firm whose financial stability is tethered to volatile, milestone-driven revenue rather than recurring product sales. While the company maintains a cash position of $46.8M as of 2026Q1, the persistent negative operating margins and an accumulated deficit of $69.2B highlight the significant execution risks inherent in its clinical pipeline. Investors should monitor the company's ability to secure non-dilutive funding, as the current reliance on sporadic partnership inflows may necessitate future equity dilution to sustain operations."

Verdict Logic

the company's reliance on sporadic milestone payments to offset a $7.6M operating loss in 2026Q1 suggests a high-risk profile that may lead to further shareholder dilution.

COYA Growth Metrics

Coya Therapeutics, Inc. (COYA) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM115.44%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-23.29%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-7.48%

Return on Capital

10 Years-77.43%
5 Years-90.41%
3 Years-43.88%
Last Year-47.91%

COYA Recent Earnings

Coya Therapeutics, Inc. (COYA) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 4/12 qtrs (50%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$0.32+17.9%
$0.39
Rev
$300,000+100.0%
$150,000
Q2 2026
Mar 16, 2026
Metric
Actual
Est
EPS
$0.34-24.8%
$0.27
Rev
$4M+78.0%
$2M
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.10-600.0%
$0.02
Rev
$4M+85.1%
$2M
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.36-63.6%
$0.22
Rev
$163,616-79.1%
$783,333
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$0.32vs $0.39+17.9%
$300,000vs $150,000+100.0%
Q2 2026Mar 16, 2026
$0.34vs $0.27-24.8%
$4Mvs $2M+78.0%
Q4 2025Nov 12, 2025
$0.10vs $0.02-600.0%
$4Mvs $2M+85.1%
Q3 2025Aug 12, 2025
$0.36vs $0.22-63.6%
$163,616vs $783,333-79.1%
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for Coya Therapeutics, Inc. (COYA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
COYA logoCOYACoya Therapeutics, Inc.Current
$5.50$100.15M-4.33123.57%-267.14%-51.39%—
NRXP logoNRXPNRx Pharmaceuticals, Inc.
$3.73$64.48M-2.78—-1070.26%——
INMB logoINMBINmune Bio, Inc.
$1.42$37.75M-0.76257.14%—-170.86%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$327.79$9.47B-24.32-100%—-43.02%—
ACIU logoACIUAC Immune S.A.
$2.56$260.54M-2.96-86.92%-1971.7%-101.76%—
SAVA logoSAVACassava Sciences, Inc.
$1.32$63.77M-2.54——-95.77%—

Compare COYA vs Peers

Coya Therapeutics, Inc. (COYA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs NRXP

Most directly comparable listed peer for COYA.

Scale Benchmark

vs LLY

Larger-name benchmark to compare COYA against a more recognizable public peer.

Peer Set

Compare Top 5

vs NRXP, INMB, PRAX, ACIU

COYA SEC Filings & Documents

Coya Therapeutics, Inc. (COYA) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 12, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

Apr 2, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 16, 2026·SEC

FY 2025

Mar 18, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 12, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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COYA Frequently Asked Questions

Coya Therapeutics, Inc. (COYA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Coya Therapeutics, Inc.'s revenue?

Coya Therapeutics, Inc. (COYA) reported $7.9M in revenue for fiscal year 2025.

How fast is Coya Therapeutics, Inc. growing?

Coya Therapeutics, Inc. (COYA) grew revenue by 123.6% over the past year. This is strong growth.

Is COYA profitable?

Coya Therapeutics, Inc. (COYA) reported a net loss of $21.1M for fiscal year 2025.

Dividend & Returns
What is COYA's return on equity?

Coya Therapeutics, Inc. (COYA) has a return on equity (ROE) of -51.4%. Negative ROE indicates the company is unprofitable.

What is Coya Therapeutics, Inc.'s free cash flow?

Coya Therapeutics, Inc. (COYA) had negative free cash flow of $14.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in COYA back in 2020?

Total return calculator · dividends reinvested · 6+ years of data

See returns →