Last 48 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -2.23 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 177.55 | 675.16 | 193.23 | 287.02 | 432.97 | 343.17 | 342.39 | 189.59 | 152.63 | 290.95 | 105.96 | 110.11 | 152.03 |
| — | +96.7% | -43.6% | +51.4% | +183.7% | +17.9% | +223.1% | +72.2% | +0.4% | +31.0% | -13.3% | -38.6% | -41.9% | |
| P/B Ratio | 2.27 | 3.19 | 4.14 | 2.82 | 3.58 | 2.11 | 2.49 | 2.53 | 1.90 | 3.92 | 0.95 | 0.80 | 0.76 |
| — | +51.1% | +66.0% | +11.5% | +88.2% | -46.1% | +162.9% | +217.5% | +150.4% | +412.9% | +61.2% | +35.4% | -4.1% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Cardiff Oncology, Inc.'s operating margin was -31341.5% in Q1 2026, down 28120.5 pp QoQ and down 18147.0 pp YoY. The trailing four-quarter average of -14188.3% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 539.0% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | -439.0% | 100.0% | 100.0% | -9470.2% | 100.0% | 100.0% | -5742.4% | 35.6% | 50.2% | 34.0% | 24.1% | 100.0% |
| — | -539.0% | 0.0% | +101.7% | -26714.7% | +99.0% | +194.3% | -23914.1% | -64.4% | -49.8% | -66.0% | -75.9% | 0.0% | |
| Operating Margin | -8256.3% | -31341.5% | -3221.0% | -9978.3% | -12212.4% | -13194.5% | -8325.8% | -7637.0% | -7696.3% | -5333.2% | -6623.1% | -7673.8% | -11303.7% |
| — | -137.5% | +61.3% | -30.7% | -58.7% | -147.4% | -25.7% | +0.5% | +31.9% | +63.3% | +9.7% | +20.6% | +1.5% | |
| Net Margin | -7732.0% | -30124.4% | -2969.5% | -9381.7% | -11523.1% | -12324.8% | -7806.0% | -7184.8% | -7225.8% | -4883.4% | -5985.3% | -6901.4% | -10324.1% |
| — | -144.4% | +62.0% | -30.6% | -59.5% | -152.4% | -30.4% | -4.1% | +30.0% | +63.9% | +11.9% | +25.1% | +10.0% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -71.5% | -30.8% | -15.3% | -21.0% | -21.5% | -17.5% | -17.8% | -23.3% | -20.8% | -15.3% | -12.7% | -11.8% | -12.2% |
| — | -76.6% | +14.0% | +10.0% | -3.6% | -14.0% | -40.8% | -96.8% | -70.7% | -38.5% | -59.7% | -61.4% | -46.1% | |
| ROA | -57.6% | -22.2% | -11.5% | -16.1% | -17.4% | -14.8% | -14.7% | -18.4% | -16.8% | -12.9% | -11.0% | -10.5% | -10.9% |
| — | -50.7% | +22.0% | +12.2% | -3.3% | -14.8% | -34.1% | -75.6% | -53.8% | -27.6% | -51.4% | -55.7% | -41.6% | |
| ROIC | -118.9% | -34.7% | -17.2% | -20.3% | -22.8% | -26.6% | -26.5% | -28.3% | -25.8% | -17.4% | -13.5% | -12.1% | -11.9% |
| — | -30.5% | +35.4% | +28.4% | +11.5% | -53.2% | -97.2% | -134.7% | -116.5% | -69.8% | -81.6% | -78.7% | -64.0% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 47.4% YoY to 3.27x, tightening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.03 | 0.04 | 0.03 | 0.03 | 0.03 | 0.03 |
| — | -2.7% | -0.2% | -39.4% | -42.5% | -41.7% | -40.4% | +15.8% | +25.0% | +22.8% | +20.7% | +17.2% | +13.9% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 3.67 | 3.27 | 3.67 | 4.20 | 4.42 | 6.22 | 7.08 | 4.74 | 4.97 | 5.91 | 7.41 | 9.30 | 10.16 |
| — | -47.4% | -48.2% | -11.3% | -11.1% | +5.3% | -4.5% | -49.1% | -51.1% | -52.7% | -48.0% | -35.9% | -32.3% | |
| Quick Ratio | 3.67 | 3.27 | 3.67 | 4.20 | 4.42 | 6.22 | 7.08 | 4.74 | 4.97 | 5.91 | 7.41 | 9.30 | 10.16 |
| — | -47.4% | -48.2% | -11.3% | -11.1% | +5.3% | -4.5% | -49.1% | -51.1% | -52.7% | -48.0% | -35.9% | -32.3% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 48 years · Updated daily
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Cardiff Oncology, Inc.'s current P/E is -2.2x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Cardiff Oncology, Inc.'s current operating margin is -8256.3%. Margins have been compressing over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Cardiff Oncology, Inc.'s business trajectory between earnings reports.