Cryoport, Inc. (CYRX) Financial Ratios
23 years of historical data (2003–2025) · Industrials · Integrated Freight & Logistics
EV/EBITDA
↓
N/A
—
5yr avg: 868.83
P/FCF
N/A
—
5yr avg: N/A
P/B Ratio
↓
1.50
↓-18% vs avg
5yr avg: 1.82
30Y Low0.9·High47.0
ROE
↑
15.5%
↓+168% vs avg
5yr avg: -22.8%
30Y Low-483%·High16%
Debt/EBITDA
↑
N/A
—
5yr avg: 178.45
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
CYRX Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Cryoport, Inc. trades at 10.7x earnings, 56% above its 5-year average of 6.9x, sitting at the 100th percentile of its historical range. Compared to the Industrials sector median P/E of 25.6x, the stock trades at a discount of 58%.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $753M | $481M | $379M | $759M | $797M | $2.7B | $1.7B | $550M | $311M | $197M | $46M |
| Enterprise Value | $734M | $461M | $585M | $1.1B | $1.2B | $3.0B | $1.8B | $507M | $289M | $182M | $41M |
| P/E Ratio → | 10.72 | 6.86 | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 4.28 | 2.73 | 1.63 | 3.20 | 3.58 | 12.21 | 21.51 | 16.19 | 15.85 | 16.50 | 6.00 |
| P/B Ratio | 1.50 | 0.96 | 0.94 | 1.55 | 1.43 | 4.23 | 4.42 | 4.35 | 8.07 | 11.03 | 8.11 |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | 334.42 | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
CYRX EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 2.62 | 2.51 | 4.76 | 5.37 | 13.50 | 22.71 | 14.94 | 14.70 | 15.24 | 5.40 |
| EV / EBITDA | — | — | — | — | 494.69 | 1242.97 | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — | — |
CYRX Profitability
Margins and return-on-capital ratios measuring operating efficiency
Cryoport, Inc. earns an operating margin of -20.9%, below the Industrials sector average of 4.3%. Operating margins have compressed from -13.4% to -20.9% over the past 3 years, signaling potential cost pressures or competitive headwinds. ROE of 15.5% indicates solid capital efficiency, compared to the sector median of 8.2%.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 47.1% | 47.1% | 42.6% | 43.8% | 43.4% | 43.4% | 46.2% | 51.1% | 52.2% | 49.9% | 40.4% |
| Operating Margin | -20.9% | -20.9% | -49.4% | -13.4% | -8.0% | -8.0% | -38.1% | -52.1% | -44.0% | -66.0% | -114.2% |
| Net Profit Margin | 39.9% | 39.9% | -42.7% | -15.7% | -123.8% | -123.8% | -41.5% | -54.0% | -48.7% | -66.1% | -170.8% |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 15.5% | 15.5% | -22.4% | -7.1% | -46.0% | -53.8% | -12.8% | -22.2% | -33.9% | -67.0% | -245.8% |
| ROA | 9.6% | 9.6% | -12.0% | -3.7% | -25.6% | -33.1% | -9.5% | -19.0% | -24.9% | -55.7% | -168.4% |
| ROIC | -5.1% | -5.1% | -11.8% | -2.6% | -1.4% | -1.9% | -8.0% | -26.6% | -68.9% | -301.3% | -726.6% |
| ROCE | -6.2% | -6.2% | -14.8% | -3.3% | -1.7% | -2.2% | -9.3% | -19.2% | -24.1% | -65.9% | -161.3% |
CYRX Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
The company holds a net cash position — cash of $250M exceeds total debt of $231M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.46 | 0.46 | 0.62 | 0.85 | 0.78 | 0.67 | 0.34 | 0.04 | 0.38 | — | 0.11 |
| Debt / EBITDA | — | — | — | — | 180.28 | 176.61 | — | — | — | — | — |
| Net Debt / Equity | — | -0.04 | 0.51 | 0.76 | 0.72 | 0.45 | 0.25 | -0.34 | -0.59 | -0.84 | -0.81 |
| Net Debt / EBITDA | — | — | — | — | 165.14 | 119.09 | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — | — |
| Interest Coverage | -15.59 | -15.59 | -17.05 | -4.71 | -57.40 | -57.40 | -11.79 | -12.37 | -136.69 | -502.02 | -98.88 |
Net cash position: cash ($250M) exceeds total debt ($231M)
CYRX Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
Cryoport, Inc.'s current ratio of 2.17x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has declined from 11.73x to 2.17x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.17 | 2.17 | 5.29 | 11.73 | 14.79 | 16.26 | 4.20 | 18.85 | 16.91 | 7.92 | 2.73 |
| Quick Ratio | 2.07 | 2.07 | 4.94 | 11.16 | 14.11 | 15.88 | 3.90 | 18.77 | 16.84 | 7.86 | 2.69 |
| Cash Ratio | 1.88 | 1.88 | 4.05 | 10.01 | 12.81 | 14.74 | 2.66 | 17.27 | 15.44 | 6.88 | -1247.16 |
| Asset Turnover | — | 0.23 | 0.33 | 0.25 | 0.21 | 0.20 | 0.14 | 0.25 | 0.35 | 0.59 | 0.95 |
| Inventory Turnover | 4.02 | 4.02 | 5.96 | 5.09 | 4.55 | 7.64 | 4.02 | 35.00 | 42.57 | 52.16 | 51.14 |
| Days Sales Outstanding | — | 69.11 | 71.63 | 64.72 | 71.91 | 64.62 | 145.53 | 76.33 | 65.90 | 49.63 | 56.83 |
CYRX Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Cryoport, Inc. returns 1.3% to shareholders annually primarily through share buybacks. The earnings yield of 9.3% (inverse of P/E) provides a useful comparison to bond yields when assessing the stock's relative attractiveness to fixed income.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | 9.3% | 14.6% | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 1.3% | 2.1% | 0.0% | 0.0% | 4.8% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 1.3% | 2.1% | 0.0% | 0.0% | 4.8% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Shares Outstanding | — | $50M | $49M | $49M | $46M | $46M | $39M | $33M | $28M | $23M | $14M |
Peer Comparison
Compare CYRX with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 CYRXYou | $753M | 10.7 | — | — | 47.1% | -20.9% | 15.5% | -5.1% | — |
 LQDA | $6B | -88.8 | — | — | 91.6% | -32.5% | -113.0% | -102.5% | — |
 FWRD | $431M | -3.9 | 13.1 | 28.2 | 20.5% | 1.5% | -48.2% | 1.2% | 11.4 |
 XPOF | $255M | -4.6 | 8.1 | 10.3 | 75.6% | 25.3% | — | 69.7% | 5.7 |
 IART | $1B | -2.6 | 14.4 | — | 51.7% | 4.2% | -39.9% | 1.7% | 9.3 |
 UPS | $89B | 16.0 | 9.5 | 18.7 | 18.5% | 9.6% | 33.8% | 16.1% | 2.6 |
 FDX | $78B | 19.4 | 10.6 | 26.1 | 21.6% | 6.9% | 14.7% | 7.7% | 3.6 |
 CHRW | $22B | 38.3 | 26.1 | 24.5 | 8.4% | 4.9% | 32.9% | 18.0% | 1.8 |
 XPO | $23B | 75.6 | 22.3 | 71.2 | 12.0% | 8.9% | 18.3% | 9.3% | 3.8 |
 ILMN | $25B | 29.7 | 22.7 | 26.4 | 66.7% | 19.9% | 33.4% | 16.8% | 2.3 |
 BIO | $8B | 10.1 | 18.1 | 20.4 | 52.0% | 10.5% | 10.8% | 2.6% | 3.2 |
| Industrials Median | — | 25.6 | 13.8 | 20.0 | 32.0% | 4.3% | 8.2% | 6.1% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 23 years · Updated daily
Consensus-Based Analysis Tools
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Check Valuation
Historical Returns
10-year return with dividends reinvested.
Calculate
DCA Calculator
See how regular investing compounds over time.
Run Numbers
Peer Comparison
Compare growth, multiples, and margins vs sector.
Compare
CYRX — Frequently Asked Questions
Quick answers to the most common questions about buying CYRX stock.
What is Cryoport, Inc.'s P/E ratio?
Cryoport, Inc.'s current P/E ratio is 10.7x. The historical average is 6.9x. This places it at the 100th percentile of its historical range.
What is Cryoport, Inc.'s ROE?
Cryoport, Inc.'s return on equity (ROE) is 15.5%. The historical average is -129.6%.
Is CYRX stock overvalued?
Based on historical data, Cryoport, Inc. is trading at a P/E of 10.7x. This is at the 100th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
What are Cryoport, Inc.'s profit margins?
Cryoport, Inc. has 47.1% gross margin and -20.9% operating margin.