Last 34 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -18.20 | — | 3.98 | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 1567.68 | 2176.52 | 1371.03 | 938.89 | 864.47 | 139.56 | 143.99 | 107.90 | 118.87 | 220.24 | 25.77 | 14.45 | 11.86 |
| — | +1459.5% | +852.2% | +770.2% | +627.3% | -36.6% | +458.7% | +646.7% | +902.0% | +769.8% | +405.7% | -18.9% | — | |
| P/B Ratio | 5.86 | 3.36 | 3.16 | 2.72 | 2.20 | 1.98 | 2.17 | 2.77 | 2.47 | 2.07 | 0.28 | 0.30 | 0.62 |
| — | +69.8% | +45.7% | -1.9% | -11.0% | -4.4% | +676.6% | +826.6% | +301.2% | +231.9% | -14.2% | -55.6% | +18.5% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | 8.13 | — |
| — | — | — | — | — | — | — | — | — | — | — | +539.1% | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Dianthus Therapeutics, Inc.'s operating margin was -10050.3% in Q1 2026, up 14435.9 pp QoQ and down 7197.6 pp YoY. The trailing four-quarter average of -15701.8% lags the current quarter, suggesting the recent improvement is above-trend. Gross margin contracted 16.4% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | 83.6% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 97.9% | 91.3% |
| — | -16.4% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | +2.1% | +9.5% | 0.0% | +4.4% | -2.1% | — | |
| Operating Margin | -8739.3% | -10050.3% | -24486.3% | -10173.7% | -18096.9% | -2852.7% | -2406.9% | -1376.6% | -1191.8% | -2041.6% | -2835.0% | -1705.5% | -1215.3% |
| — | -252.3% | -917.3% | -639.0% | -1418.4% | -39.7% | +15.1% | +19.3% | +1.9% | -26.5% | -211.5% | -142.4% | — | |
| Net Margin | -7973.3% | -8819.4% | 34473.6% | -9284.1% | -16388.1% | -2537.5% | -2144.8% | -1159.0% | -945.1% | -1573.0% | -2311.4% | -1597.7% | -1149.6% |
| — | -247.6% | +1707.3% | -701.0% | -1634.0% | -61.3% | +7.2% | +27.5% | +17.8% | -5.6% | -168.5% | -140.8% | — |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -38.4% | -4.8% | 18.8% | -8.7% | -10.0% | -8.7% | -8.2% | -7.2% | -4.8% | -5.1% | -6.1% | -11.7% | -14.7% |
| — | +44.4% | +328.6% | -19.7% | -107.9% | -70.7% | -35.4% | +38.0% | +67.1% | +45.9% | +40.6% | -94.7% | -21.7% | |
| ROA | -35.9% | -4.6% | 17.7% | -8.1% | -9.4% | -8.2% | -7.8% | -7.0% | -4.7% | -4.9% | -5.7% | -10.9% | -13.7% |
| — | +43.8% | +326.2% | -16.9% | -100.1% | -66.9% | -37.5% | +36.1% | +65.9% | +42.5% | +30.6% | -137.3% | -47.0% | |
| ROIC | -34.4% | -6.9% | -11.2% | -7.7% | -8.6% | -7.6% | -7.5% | -12.9% | -37.9% | -33.2% | -33.0% | -70.1% | -45.1% |
| — | +10.4% | -48.1% | +39.9% | +77.4% | +77.0% | +77.2% | +81.7% | +16.1% | -148.5% | -218.6% | -1078.4% | -273.2% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has improved 83.0% YoY to 29.25x, strengthening the short-term liquidity position.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | — |
| — | -73.3% | -33.6% | +155.7% | +286.3% | +218.4% | +22.1% | -75.5% | — | — | -67.6% | -98.5% | — | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 13.32 | 29.25 | 13.32 | 17.35 | 13.12 | 15.99 | 15.22 | 18.30 | 36.46 | 42.52 | 18.42 | 14.64 | 19.49 |
| — | +83.0% | -12.5% | -5.2% | -64.0% | -62.4% | -17.4% | +25.0% | +87.0% | +204.8% | +84.7% | +43.2% | +54.5% | |
| Quick Ratio | 13.32 | 29.25 | 13.32 | 17.35 | 13.12 | 15.99 | 15.22 | 18.30 | 36.46 | 42.52 | 18.42 | 14.64 | 19.49 |
| — | +83.0% | -12.5% | -5.2% | -64.0% | -62.4% | -17.4% | +25.0% | +87.0% | +204.8% | +84.7% | +43.2% | +54.5% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 34 years · Updated daily
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Dianthus Therapeutics, Inc.'s current P/E is -18.2x. The average P/E over the last 1 quarters is 4.0x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Dianthus Therapeutics, Inc.'s current operating margin is -8739.3%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Dianthus Therapeutics, Inc.'s business trajectory between earnings reports.