Cumulative ten-quarter operating cash outflow of -$102.0M versus cumulative net losses of -$209.1M — a gap largely explained by ~$48.5M of cumulative stock-based compensation addbacks — suggests reported burn of -$10.0M in 2026Q3 may understate true economic costs, with working capital swings like the +$32.3M milestone-driven print in 2025Q3 masking cash-flow volatility.
Enanta Pharmaceuticals, Inc. (ENTA) cash flow statement — 15-year operating, investing & financing cash flows
| Metric | TTM | Sep'25 | Sep'24 | Sep'23 | Sep'22 | Sep'21 | Sep'20 | Sep'19 | Sep'18 | Sep'17 | Sep'16 | Sep'15 | Sep'14 | Sep'13 | Sep'12 | Sep'11 |
|---|
| Cash from Operations | -35.32M | -19.27M | -78.76M | -103.15M | -84.78M | -70M | 7.09M | 71.42M | 29.22M | 52.65M | 35.81M | 76.67M | 20.18M | 10.65M | 22.62M | 24.02M |
| Operating CF Margin % | - | -29.5% | -116.45% | -130.24% | -98.4% | -72.11% | 5.79% | 34.8% | 14.14% | 51.21% | 40.57% | 47.66% | 42.27% | 33.24% | 54.24% | 57.35% |
| Operating CF Growth % | -42.04% | 75.53% | 23.64% | -21.67% | -21.12% | -1087.53% | -90.08% | 144.41% | -44.5% | 47.04% | -53.3% | 279.96% | 89.42% | -52.91% | -5.81% | - |
| Net Income | -63.23M | -81.89M | -116.05M | -133.82M | -121.75M | -79M | -36.17M | 46.38M | 71.96M | 17.71M | 21.67M | 78.99M | 34.44M | 9.63M | 21.4M | 23.31M |
| Depreciation & Amortization | 4.93M | 5.09M | 2.34M | 2.37M | 2.97M | 3.33M | 3.64M | 3.26M | 2.52M | 2.14M | 1.66M | 639K | 352K | 221K | 172K | 499K |
| Stock-Based Compensation | 15.28M | 18.57M | 26.8M | 28.22M | 26.97M | 20.99M | 19.57M | 19.23M | 15.85M | 13.07M | 9.35M | 5.84M | 2.68M | 1.06M | 424K | 225K |
| Deferred Taxes | 0 | 0 | 0 | 0 | 0 | 345K | 10.61M | -3.14M | 1.86M | -1.65M | -2.29M | 11.03M | -15.21M | 781K | 0 | -360K |
| Other Non-Cash Items | 2.74M | -946K | 1.02M | -7.95M | 242K | -1.98M | -3.47M | -5.8M | -1.17M | -581K | -749K | -2.99M | 176K | -1.78M | 535K | 2.75M |
| Working Capital Changes | 4.97M | 39.91M | 7.13M | 8.02M | 6.79M | -13.69M | 12.9M | 11.49M | -61.79M | 21.97M | 6.17M | -16.83M | -2.26M | 741K | 93K | -2.4M |
| Change in Receivables | 1.8M | 31.76M | 973K | 9.42M | 11.79M | -24.3M | 27.82M | 15.89M | -56.59M | 2.23M | 2.45M | -13.56M | -916K | 241K | -788K | -251K |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -6.48M | -6.42M | 18.63M | 1.88M | -3.37M | -1.73M | 370K | 96K | -1.39M |
| Change in Payables | 616K | -1.31M | -414K | -1.15M | -4.63M | 3.77M | -883K | 1.79M | 1.32M | 633K | 1.45M | -543K | 399K | 115K | 763K | 58K |
| Cash from Investing | -19.05M | 40.35M | 58.23M | -53.58M | 54.9M | 36.99M | 19.83M | -86.66M | -35.4M | -4.57M | -43.66M | -88.19M | 497K | -69.22M | -18.04M | -17.68M |
| Capital Expenditures | -1.62M | -12.9M | -17.95M | -9.06M | -2.13M | -750K | -1.45M | -5.42M | -2.98M | -2.51M | -4.74M | -2.34M | -1.03M | -606K | -252K | -445K |
| CapEx % of Revenue | 2.49% | 19.74% | 26.54% | 11.44% | 2.47% | 0.77% | 1.18% | 2.64% | 1.44% | 2.44% | 5.37% | 1.45% | 2.15% | 1.89% | 0.6% | 1.06% |
| Acquisitions | 0 | 0 | 0 | 44.52M | -54.9M | -37.74M | 0 | 86.66M | 0 | 0 | 0 | 9K | 0 | 0 | 66K | 9K |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | -44.52M | 54.9M | 37.74M | 0 | 0 | -32.42M | -2.07M | -38.92M | -172K | 3K | -68.61M | 1.14M | -436K |
| Cash from Financing | 42.98M | -26.62M | -27.63M | 198.13M | 20.03M | 3.08M | 8.98M | 2.57M | 4.41M | 1.02M | 2.71M | 2.54M | 1.16M | 56.91M | -909K | 34K |
| Debt Issued (Net) | -32.34M | -26.49M | -27.48M | 199.68M | 0 | 0 | 0 | -86K | -79K | -73K | -68K | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 70.68M | 145K | 147K | 2.21M | 21.26M | 3.61M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 59.89M | 0 | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 4.64M | -277K | -294K | -3.76M | -1.23M | -534K | 8.98M | 2.66M | 4.49M | 1.09M | 2.77M | 2.54M | 1.16M | -2.98M | -909K | 34K |
| Net Change in Cash | -11.39M | -5.54M | -48.16M | 41.39M | -9.85M | -29.93M | 35.9M | -12.67M | -1.77M | 49.1M | -5.15M | -8.97M | 21.84M | -1.65M | 3.67M | 6.37M |
| Free Cash Flow | -36.94M | -32.17M | -96.71M | -112.21M | -86.91M | -70.75M | 5.64M | 66M | 26.24M | 50.15M | 31.07M | 74.34M | 19.15M | 10.05M | 22.37M | 23.57M |
| FCF Margin % | -56.6% | -49.24% | -142.99% | -141.67% | -100.87% | -72.88% | 4.61% | 32.16% | 12.7% | 48.77% | 35.2% | 46.21% | 40.11% | 31.34% | 53.64% | 56.29% |
| FCF Growth % | 15.22% | 66.74% | 13.81% | -29.12% | -22.84% | -1353.69% | -91.45% | 151.54% | -47.68% | 61.39% | -58.2% | 288.16% | 90.61% | -55.09% | -5.1% | - |
| FCF per Share | -1.27 | -1.51 | -4.57 | -5.35 | -4.22 | -3.51 | 0.28 | 3.15 | 1.27 | 2.58 | 1.62 | 3.85 | 1.00 | 1.03 | 2.39 | 1.84 |
| FCF Conversion (FCF/Net Income) | 0.58x | 0.24x | 0.68x | 0.77x | 0.70x | 0.89x | -0.20x | 1.54x | 0.41x | 2.97x | 1.65x | 0.97x | 0.59x | 1.11x | 1.06x | 1.03x |
| Interest Paid | -3.84M | 8.79M | 11.71M | 1.99M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 109K | 241K | 4.9M | 0 | 32K | 105K | 12.67M | 26.09M | 1.59M | 12.62M | 40.07M | 148K | 0 | 0 | 0 |
Quick answers to the most common questions about buying ENTA stock.
Enanta Pharmaceuticals, Inc. (ENTA) generated $-19.3M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Enanta Pharmaceuticals, Inc. (ENTA) reported negative free cash flow of $32.2M in 2025, indicating capital requirements exceeded cash from operations.
Enanta Pharmaceuticals, Inc. (ENTA) spent $12.9M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
Milestone timing masks burn quality
Metrics are mathematically derived from official filings.
Cash Burn Runs Below Reported Losses
Enanta's operating cash burn has consistently run below its reported net loss — cumulative OCF of -$102.0M versus cumulative net losses of -$209.1M over ten quarters, per the company's quarterly statements — with the ~$48.5M cumulative SBC addback largely explaining the difference.
The sub-1.0 OCF/NI ratios (0.35 in 2025Q4, 0.51 in 2026Q3, 0.55 in 2026Q2) indicate that reported losses overstate cash consumption, with the ~$3.7M–$4.7M quarterly stock-based compensation addback and roughly $1.2M of D&A bridging most of the gap. Because Enanta's revenue is milestone- and royalty-based with gross margins at or near 100%, the accrual profile appears to be driven more by expense recognition and payment timing than by inventory or receivables mechanics — implying the quality of the OCF shortfall is unusually dependent on non-cash addbacks rather than genuine operating cash absorption.
FCF Narrowing Tracks Cost Cuts, Not Revenue
Free cash flow burn narrowed from -$30.3M in 2024Q2 to -$10.0M in 2026Q3, improving the quarterly FCF margin from -177.5% to -69.5% based on Enanta's reported figures, though the improvement appears driven by cost retrenchment rather than a revenue-driven inflection.
The roughly 67% reduction in quarterly FCF outflow is real and material, but the path is not monotonic — 2026Q3's net loss widened sequentially to -$19.5M from -$13.1M, so the FCF trend reflects quarter-to-quarter expense and timing variance rather than a clean trajectory. The improvement correlates closely with the ~38% R&D reduction identified in prior analysis rather than any revenue recovery, which suggests the burn trajectory is a function of discretionary spend control and could reverse if pipeline commitments resume.
Milestone Timing Distorts Cash Volatility
Working capital contributed +$32.3M to operating cash flow in 2025Q3 — a single-quarter swing that produced the only positive OCF print in ten quarters — and the lumpiness suggests milestone receipt timing rather than operational efficiency, per Enanta's quarterly disclosures.
The same line item swung from -$2.9M in 2026Q1 to +$2.5M in 2026Q3 and +$9.2M in 2024Q4, producing extreme quarter-to-quarter OCF volatility that appears consistent with the receipt and recognition of contract milestones rather than a structurally tightening operating cycle. Excluding the 2025Q3 outlier, cumulative working capital contributions across the other nine quarters are comparatively modest, so investors should not read the single positive OCF print as evidence of improving collections or payables management; the supplied data does not disclose receivable aging or contract asset balances, which warrants further investigation.
Capex Collapse Leaves Depreciation Unreplaced
Capex collapsed from $8.7M, or 51.6% of revenue, in 2025Q1 to just $7K in 2026Q3, while quarterly depreciation of $1.2M continues to run far ahead of reinvestment, according to Enanta's cash flow statements.
Roughly $30.3M of cumulative capex across 2024Q2–2025Q1 has given way to approximately $0.16M over the last three quarters, which appears consistent with the completion of a prior lab build-out rather than a sudden collapse in operating needs. For a royalty-model business this low capital intensity aligns with the near-100% gross margin economics, yet the sustained gap between $1.2M of quarterly depreciation and negligible reinvestment suggests the physical research platform is being consumed without replacement — a pattern that may constrain future pipeline productivity.
Cumulative Losses Overstate Cash Reality
Across ten quarters, cumulative net losses of -$209.1M compare with cumulative operating cash outflow of only -$102.0M, per Enanta's reported filings, a ~$107M gap that appears driven by non-cash items rather than superior cash conversion.
That ~$107M divergence decomposes largely into roughly $48.5M of cumulative stock-based compensation, about $9.3M of D&A, and the lumpy net working capital timing discussed above — meaning the cash reality is materially less severe than the accounting loss profile, but the cushion is a function of non-cash compensation and payment timing rather than operating performance. The supplied data contains no cash balance, debt, or maturity information, so the implied funding runway cannot be assessed here; investors should monitor the balance sheet alongside these flows to determine how many quarters of burn the current liquidity position supports.
Burn Optics May Mask Pipeline Retrenchment
The reported ~$107M cushion between cumulative net loss and operating cash flow is largely absorbed by $48.5M of cumulative stock-based compensation and depreciation, meaning reported burn may understate the true economic cost of Enanta's retained workforce and research base.
Prior analysis indicated the ~47% reduction in operating loss came almost entirely from an ~$18M annualized R&D cut while revenue fell 21.6% year-over-year to $14.4M, so the cash flow improvement appears to have been purchased with pipeline optionality rather than earned — a trade-off that could reverse the FCF trajectory if the company restarts spending. SBC of $3.7M per quarter, though down from $7.7M in 2024Q4, is added back in full yet represents real dilution to shareholders, and the near-zero recent capex alongside unchanged $1.2M depreciation raises further questions about undisclosed commitments or asset consumption underlying the reported figures.