Cash flow generation remains volatile, evidenced by a wide range in the operating cash flow to net income ratio from 0.11 in 2025Q2 to 2.92 in 2024Q3, reflecting irregular capital deployment.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | 1.52B | 1.41B | 335.34M | 496.49M | 969.94M | 749.49M | -124.6M | 710.66M | 336.23M | -92.99M | 304.76M | 86.54M | 26.26M | 9.18M | -94.83M | -161.72M | 97.94M | 12.36M | -140.86M | -92.69M | -50.37M | -101.87M | -114.67M | -118.33M | -58.27M | -47M | -7.34M | -21.4M | 36.2M | 18.7M | 16M |
| Operating CF Margin % | - | 27.49% | 7.91% | 13.43% | 28.57% | 25.1% | -4.67% | 32.92% | 17.87% | -6.05% | 27.56% | 11.48% | 5.13% | 2.59% | -31.92% | -171.21% | 57.65% | 133.38% | -3594.28% | -269.15% | -182.21% | -1298.39% | -810.6% | -251.28% | -57.34% | -21.44% | -3.78% | -13.63% | 26.85% | 21.15% | 38.28% |
| Operating CF Growth % | 269.05% | 321.52% | -32.46% | -48.81% | 29.41% | 701.52% | -117.53% | 111.36% | 461.58% | -130.51% | 252.17% | 229.59% | 186.01% | 109.68% | 41.36% | -265.12% | 692.51% | 108.77% | -51.96% | -84.04% | 50.56% | 11.16% | 3.1% | -103.09% | -23.96% | -540.03% | 65.68% | -159.12% | 93.58% | 16.88% | 277.78% |
| Net Income | 1.43B | 1.29B | 32.62M | 597.6M | 340.66M | 948.58M | -295.7M | 446.91M | 109.49M | -313.14M | 104.22M | 6.53M | -48.48M | -83.15M | -44.32M | -186.54M | -31.85M | -211.87M | -178.92M | -86.88M | -74.17M | -103.04M | -164.82M | -166.46M | -136.88M | -183.24M | -32.87M | -26.8M | 3.5M | 10.4M | -6.8M |
| Depreciation & Amortization | 94.73M | 93.29M | 89.25M | 82.66M | 67.86M | 57.84M | 51.81M | 54.53M | 54.97M | 52.18M | 58.42M | 44.88M | 41.41M | 29.21M | 29.98M | 26.99M | 24.48M | 16.69M | 13.07M | 12.96M | 7.41M | 8.19M | 13.91M | 17.68M | 23.21M | 47.66M | 34.84M | 24.7M | 17.8M | 10.4M | 6.5M |
| Stock-Based Compensation | 190.33M | 249.35M | 266.06M | 215.89M | 188.42M | 183.01M | 177.88M | 166.59M | 148.15M | 133.06M | 96.2M | 69.87M | 62.16M | 38.4M | 38.49M | 28.98M | 14.86M | 9.98M | 15.03M | 8.89M | 8.89M | 186K | 463K | 4.1M | 4.1M | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | 317.81M | 247.69M | -85.55M | -158.9M | 57.09M | -465.6M | -350K | -377K | -459K | 91.16M | 3.26M | 1.71M | -41.13M | -3K | -30.53M | 186.72M | 3.81M | 41.37M | -15.03M | -17.37M | -15.17M | -186K | -463K | -4.1M | -4.1M | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 102.74M | 63.69M | -105.28M | 7.89M | 117.11M | 40.23M | 13.51M | -14.29M | 70.61M | 7.99M | 17.89M | -1.61M | 41.41M | 29.21M | 29.98M | -186.63M | -379K | 2.01M | 15.48M | 9.65M | 9.65M | -944K | 39.92M | 52.75M | 27.18M | 114.04M | -3.1M | 5.5M | 12.7M | 0 | 3M |
| Working Capital Changes | -620.6M | -527.16M | 138.24M | -248.65M | 198.81M | -14.57M | -71.74M | 57.3M | -46.54M | -64.23M | 24.75M | -34.85M | -29.12M | -4.48M | -118.43M | -31.25M | 87.02M | 154.18M | 9.51M | -19.95M | 13.02M | -6.08M | -3.69M | -22.31M | 28.23M | -25.48M | -6.21M | -24.8M | 2.2M | -2.1M | 13.3M |
| Change in Receivables | -228.75M | -170.77M | -111.59M | -98.68M | -28.58M | -134.31M | -173.19M | -1.21M | -41.3M | -117.54M | -23.95M | -56.52M | -22.56M | 35.58M | -64.54M | -714K | 157.96M | -162.61M | 501K | -650K | -650K | 721K | 3.08M | 45.55M | 45.55M | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | -42.16M | -58.51M | -127.63M | -170.15M | -67.5M | -20.96M | -19.47M | -6.1M | 4.04M | 4.85M | 4.05M | 98K | -4.09M | -6.59M | -5.22M | -3.54M | 6.25M | 6.37M | -154.02M | 4.19M | -8.07M | -334.17M | -452.45M | -323.09M | -400.13M | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 32.17M | 6.56M | 88.16M | -167.94M | 105.44M | 73.34M | 15.12M | -20.18M | 36.16M | -7.93M | 43.76M | 5.62M | 5.36M | 5.14M | -978K | 4.17M | -10.19M | 5.29M | 7.87M | 2.34M | 2.34M | 1.25M | -4.15M | 1.73M | 1.73M | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | -191.91M | -102.61M | 157.52M | -207.68M | -78.54M | -207.7M | -269M | -87.45M | -86.42M | -349.98M | -232.49M | -105.01M | -138.44M | -37.4M | -1.99M | -2.5M | 15.2M | 16.45M | 105.89M | 170.36M | 26.04M | 15.53M | -77.16M | 126.35M | 41.23M | -25.56M | -533.69M | -8.7M | -45.4M | -65.4M | -20.4M |
| Capital Expenditures | -65.9M | -58.87M | -86.26M | -47.49M | -77.83M | -181.01M | -187.38M | -78.06M | -73.48M | -111.02M | -120.28M | -26M | -27.88M | -4.27M | -2.84M | -3.8M | -4.11M | -387K | -698K | -1.15M | -1.57M | -1.63M | -1.39M | -9.74M | -11.89M | -12.92M | -96.38M | -34.8M | -34.7M | -26.1M | -20.2M |
| CapEx % of Revenue | 1.23% | 1.15% | 2.03% | 1.28% | 2.29% | 6.06% | 7.03% | 3.62% | 3.9% | 7.23% | 10.88% | 3.45% | 5.45% | 1.2% | 0.96% | 4.02% | 2.42% | 4.18% | 17.81% | 3.35% | 5.67% | 20.81% | 9.83% | 20.68% | 11.7% | 5.89% | 49.64% | 22.17% | 25.74% | 29.52% | 48.33% |
| Acquisitions | 0 | 0 | 0 | 47.49M | 709K | 181.01M | 187.38M | 78.06M | 73.48M | 111.02M | -142.86M | 26M | 27.88M | 4.27M | 2.84M | 4.29M | 4.29M | -952K | -22K | 0 | 0 | 0 | -88K | -5.72M | -749.35M | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -30M | -25M | -13.9M | -47.49M | -709K | -181.01M | -187.38M | -78.06M | -73.48M | -111.02M | 30.64M | -26M | -27.88M | -4.27M | -2.84M | -4.11M | -4.11M | -387K | -681K | 0 | 0 | 59K | 1.63M | -1.15M | -1.15M | 300K | 0 | 0 | -7.2M | -4.3M | 0 |
| Cash from Financing | 198.54M | 101.04M | -2.02B | -20.03M | -794K | 6.18M | 71.71M | 45.71M | 14.66M | 690.17M | 58.65M | 87.62M | 93.06M | 275.59M | 47.71M | 19.47M | -145.05M | 242.25M | 104.88M | 12.32M | 31.7M | -34.35M | 294.24M | -1.17M | -3.16M | 5.77M | 619.12M | 12.5M | 4M | 90.2M | 1.5M |
| Debt Issued (Net) | -4.64M | -4.54M | -3.8M | -3.36M | -2.86M | -2.42M | -836K | -822K | 0 | 0 | -445K | -1.7M | 0 | 217.22M | 0 | 0 | -158.64M | 164.08M | 0 | 10M | 30.29M | -35.84M | 204.09M | -3.06M | -4.69M | 0 | 184.45M | -1.2M | -800K | 1M | -100K |
| Equity Issued (Net) | 290.46M | 202.66M | -2B | 35.84M | 61.12M | 58.63M | 110.31M | 63.3M | 29.94M | 649.39M | 49.97M | 86.44M | 92.84M | 73.16M | 47.71M | 19.47M | 13.59M | 134.4M | 104.88M | 2.33M | 1.41M | 1.49M | 90.15M | 1.89M | 1.46M | 11.27M | 434.65M | 13.6M | 4.7M | 93.8M | 1.6M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -25.98M | -19.1M | -2B | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -105K | -5.72M | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | -87.29M | -97.08M | -12.96M | -52.51M | -59.05M | -50.03M | -37.76M | -16.77M | -15.29M | 49.72M | 9.12M | 2.88M | 478K | -14.79M | 0 | 0 | 0 | -56.22M | 0 | 0 | 0 | 0 | 0 | 0 | 72K | -5.5M | 20K | 100K | 100K | -4.6M | 0 |
| Net Change in Cash | 1.52B | 1.41B | -1.53B | 262.1M | 893.96M | 544.39M | -318.94M | 668.72M | 264.55M | 247.17M | 130.9M | 69.14M | -19.13M | 247.37M | -49.11M | -144.75M | -31.91M | 271.06M | 69.91M | 89.99M | 7.37M | -120.69M | 102.48M | 6.77M | -20.44M | -66.79M | 77.94M | -17.8M | -5.6M | 43.5M | -2.9M |
| Free Cash Flow | 1.45B | 1.35B | 249.07M | 449M | 892.11M | 568.48M | -311.98M | 632.59M | 262.74M | -204.01M | 184.48M | 60.53M | -1.62M | 4.91M | -97.67M | -165.51M | 93.83M | 11.97M | -141.56M | -93.85M | -51.94M | -103.5M | -116.06M | -128.07M | -70.16M | -59.92M | -103.72M | -56.2M | 1.5M | -7.4M | -4.2M |
| FCF Margin % | 27.06% | 26.35% | 5.87% | 12.15% | 26.28% | 19.04% | -11.7% | 29.3% | 13.96% | -13.28% | 16.68% | 8.03% | -0.32% | 1.38% | -32.88% | -175.23% | 55.23% | 129.21% | -3612.09% | -272.49% | -187.88% | -1319.21% | -820.43% | -271.96% | -69.04% | -27.33% | -53.42% | -35.8% | 1.11% | -8.37% | -10.05% |
| FCF Growth % | 402.37% | 443.87% | -44.53% | -49.67% | 56.93% | 282.22% | -149.32% | 140.76% | 228.79% | -210.59% | 204.76% | 3836.6% | -132.97% | 105.03% | 40.99% | -276.4% | 683.8% | 108.46% | -50.84% | -80.7% | 49.82% | 10.82% | 9.38% | -82.55% | -17.08% | 42.23% | -84.56% | -3846.67% | 120.27% | -76.19% | 75.15% |
| FCF per Share | 7.01 | 6.75 | 1.18 | 1.99 | 3.98 | 2.56 | -1.43 | 2.91 | 1.22 | -1.00 | 0.95 | 0.32 | -0.01 | 0.03 | -0.75 | -1.32 | 0.77 | 0.12 | -1.58 | -1.11 | -0.62 | -1.24 | -1.56 | -1.79 | -1.04 | -0.91 | -1.64 | -1.00 | 0.03 | -0.14 | -0.11 |
| FCF Conversion (FCF/Net Income) | 1.01x | 1.10x | 10.28x | 0.83x | 2.85x | 0.79x | 0.42x | 1.59x | 3.07x | 0.30x | 2.92x | 13.25x | -0.54x | -0.11x | 2.14x | 0.87x | -3.08x | -0.06x | 0.79x | 1.07x | 0.68x | 0.99x | 0.70x | 0.71x | 0.43x | 0.26x | 0.25x | 0.80x | 10.34x | 1.80x | -2.35x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 396K | 0 | 239K | 268K | 314K | 7.22M | 12.75M | 11.29M | 15.59M | 19M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 175.59M | 0 | 373.06M | 378.21M | 136.24M | 67.73M | 70.71M | 33.55M | 5.42M | 6.3M | 927K | 62K | 37K | 140K | 1K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2028 Jakafi patent cliff
As evidenced by the quarterly cash flow statements, Incyte's operating cash flow to net income ratio has fluctuated significantly, ranging from a low of 0.11 in 2025Q2 to a high of 2.92 in 2024Q3, indicating that accounting accruals frequently decouple from actual cash generation.
The wide variance in the OCF/NI ratio suggests that reported net income is heavily influenced by non-cash items and timing differences in working capital. Investors should monitor whether this volatility reflects genuine operational shifts or merely the lumpy nature of milestone payments and stock-based compensation adjustments.
According to historical financial data, Incyte's free cash flow margins have shown extreme variability, swinging from a negative 60.5% in 2024Q2 to a peak of 39.9% in 2025Q3, reflecting the company's aggressive and often irregular capital allocation toward pipeline development and strategic share repurchases.
The inconsistent FCF trajectory implies that the company is not yet operating as a mature, steady-state cash generator. The sharp margin contractions appear tied to episodic capital deployment rather than structural deterioration in the core business, suggesting that cash flow stability remains secondary to long-term R&D objectives.
Based on reported figures, Incyte experienced a massive $583 million working capital outflow in 2025Q2, which significantly distorted the cash flow profile for that period and highlights the sensitivity of the company's liquidity to timing differences in receivables and inventory management.
Such dramatic swings in working capital suggest that the company's cash conversion cycle is prone to significant quarterly disruptions. This volatility warrants further investigation into whether these outflows represent temporary timing mismatches or a more permanent increase in the capital intensity required to support the Opzelura rollout.
As reported in recent filings, Incyte utilized $2 billion for share repurchases in 2024Q2, a move that stands in stark contrast to its otherwise conservative cash management and suggests a management preference for returning capital during periods of perceived market undervaluation.
The lumpy nature of these repurchases indicates that capital deployment is opportunistic rather than systematic. While the company maintains a fortress balance sheet, the decision to deploy large sums into buybacks while simultaneously funding high-cost R&D programs suggests a dual-track strategy of defending the stock price while attempting to bridge the 2028 revenue gap.
Quick answers to the most common questions about buying INCY stock.
Incyte Corporation (INCY) generated $1.41B in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Incyte Corporation (INCY) generated $1.35B in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Incyte Corporation (INCY) spent $58.9M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, Incyte Corporation (INCY) spent $19.1M on share repurchases. This shows the company's commitment to returning capital to its equity investors.