Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in INVA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 11.3M | $263.5M | +5.9% | 15.321% | 0.00% |
| 2 | DIMENSIONAL FUND ADVISORS LP | 4.4M | $103.4M | +1.7% | 6.011% | 0.02% |
| 3 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4.2M | $98.4M | — | 5.724% | 0.01% |
| 4 | RENAISSANCE TECHNOLOGIES LLC | 4.1M | $94.5M | -3.7% | 5.495% | 0.15% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 3.1M | $73.2M | — | 4.256% | 0.00% |
| 6 | STATE STREET CORP | 3.1M | $71.3M | +9.4% | 4.146% | 0.00% |
| 7 | MILLENNIUM MANAGEMENT LLC | 2.3M | $53.1M | +41.5% | 3.088% | 0.04% |
| 8 | Sarissa Capital Management LP | 2.1M | $49.7M | -24.3% | 2.887% | 31.50% |
| 9 | SYSTEMATIC FINANCIAL MANAGEMENT LP | 2.0M | $47.2M | -4.3% | 2.742% | 1.08% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 1.9M | $45.0M | +10.1% | 2.615% | 0.00% |
| 11 | AMERICAN CENTURY COMPANIES INC | 1.9M | $44.5M | -14.7% | 2.588% | 0.02% |
| 12 | ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | 1.9M | $44.0M | -19.9% | 2.557% | 0.02% |
| 13 | Boston Partners | 1.7M | $40.0M | +11.0% | 2.329% | 0.04% |
| 14 | BANK OF AMERICA CORP /DE/ | 1.6M | $37.7M | +6.6% | 2.195% | 0.00% |
| 15 | GOLDMAN SACHS GROUP INC | 1.6M | $37.1M | +42.0% | 2.159% | 0.00% |
| 16 | MARSHALL WACE, LLP | 1.5M | $35.1M | +8.1% | 2.038% | 0.04% |
| 17 | TWO SIGMA INVESTMENTS, LP | 1.5M | $34.6M | +76.7% | 2.011% | 0.03% |
| 18 | MORGAN STANLEY | 1.3M | $30.5M | -7.6% | 1.776% | 0.00% |
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.2M | $27.1M | +14.0% | 1.577% | 0.00% |
| 20 | ROYCE & ASSOCIATES LP | 1.1M | $24.7M | +15.3% | 1.438% | 0.24% |
| 21 | DEUTSCHE BANK AG\ | 908K | $21.2M | +6.9% | 1.230% | 0.01% |
| 22 | Invesco Ltd. | 904K | $21.1M | +8.6% | 1.225% | 0.00% |
| 23 | DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt | 892K | $20.8M | +28.0% | 1.209% | 0.02% |
| 24 | Qube Research & Technologies Ltd | 786K | $18.3M | -35.3% | 1.065% | 0.02% |
| 25 | NORTHERN TRUST CORP | 774K | $18.0M | +10.9% | 1.049% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in INVA — a direct measure of their conviction.
Filings activity in INVA during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 281 | +2.6% | 102.34% | +14.79 pp | $1.72B | +17% |
| Q4 2025 | 274 | +7.0% | 87.55% | +6.11 pp | $1.47B | +7.5% |
| Q3 2025 | 256 | 1.9% | 81.44% | 4.99 pp | $1.37B | 5.8% |
| Q2 2025 | 261 | +7.9% | 86.43% | +15.57 pp | $1.45B | +22% |
| Q1 2025 | 242 | +4.8% | 70.86% | 0.27 pp | $1.19B | 0.4% |
| Q4 2024 | 231 | +6.5% | 71.13% | 10.16 pp | $1.19B | 13% |
| Q3 2024 | 217 | +3.3% | 81.29% | +11.98 pp | $1.36B | +17% |
| Q2 2024 | 210 | — | 69.31% | — | $1.16B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying INVA stock.
Based on Q1 2026 13F filings, institutional ownership of Innoviva, Inc. stands at 102.3%, held across 281 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of INVA, with approximately 11,307,845 shares worth $0.26B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of INVA, including RENAISSANCE TECHNOLOGIES LLC, MILLENNIUM MANAGEMENT LLC, TWO SIGMA INVESTMENTS, LP.
Our composite Smart Money Score for INVA is 72 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
52 institutions opened new positions in INVA during Q1 2026, while 45 fully exited. 185 added to existing positions and 41 trimmed.
INVA institutional ownership rose by 14.79 percentage points quarter-over-quarter, with a net change of +7 holders.
The top 10 institutions account for 52.3% of all reported 13F value in INVA, and the top 25 account for 78.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Innoviva, Inc. (INVA) Institutional Ownership