66% buyers of institutions opening or closing positions this quarter
14 more new buyers than exits, ownership rose 1.82 percentage points vs the prior quarter, and no widely-followed fund managers in the top 25.
66% buyers of institutions opening or closing positions this quarter
100.9% institutional ownership
Versant Venture Management, portfolio allocation
Institutional ownership vs Biotechnology peers
No Form 4 insider transactions on file
Latest positioning in JBIO across 13F flow, ownership shift, marquee holders, and holder-count growth.
Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in JBIO held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 7.1M | $99.6M | +2.8% | 21.717% | 0.01% |
| 2 | Fairmount Funds Management LLC | 4.6M | $64.0M | 0.0% | 13.957% | 4.62% |
| 3 | RA CAPITAL MANAGEMENT, L.P. | 3.7M | $51.6M | 0.0% | 11.252% | 0.55% |
| 4 | Bellevue Group AG | 3.5M | $49.2M | +4.8% | 10.732% | 1.17% |
| 5 | VR Adviser, LLC | 3.2M | $45.2M | 0.0% | 9.871% | 1.69% |
| 6 | JANUS HENDERSON GROUP PLC | 3.1M | $43.6M | — | 9.519% | 0.02% |
| 7 | Avidity Partners Management LP | 1.4M | $34.2M | 0.0% | 4.293% | 7.73% |
| 8 | BlackRock, Inc. | 2.3M | $32.5M | -19.4% | 7.092% | 0.00% |
| 9 | VANGUARD CAPITAL MANAGEMENT LLC | 1.8M | $25.2M | — | 5.507% | 0.00% |
| 10 | BAKER BROS. ADVISORS LP | 1.6M | $23.1M | 0.0% | 5.030% | 0.13% |
| 11 | Remedium Capital Partners, LLC | 1.6M | $22.2M | 0.0% | 4.836% | 6.93% |
| 12 | Versant Venture Management, LLC | 1.5M | $21.4M | 0.0% | 4.677% | 15.16% |
| 13 | Samsara BioCapital, LLC | 969K | $13.6M | 0.0% | 2.969% | 1.32% |
| 14 | GREAT POINT PARTNERS LLC | 964K | $13.6M | +19.6% | 2.956% | 3.11% |
| 15 | MARSHALL WACE, LLP | 945K | $13.3M | +7.9% | 2.896% | 0.01% |
| 16 | abrdn plc | 867K | $12.2M | 0.0% | 2.658% | 0.02% |
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 823K | $11.6M | -2.3% | 2.521% | 0.00% |
| 18 | Soleus Capital Management, L.P. | 797K | $11.2M | 0.0% | 2.442% | 0.45% |
| 19 | ACORN CAPITAL ADVISORS, LLC | 787K | $11.1M | — | 2.412% | 3.14% |
| 20 | STATE STREET CORP | 656K | $9.2M | +2.0% | 2.010% | 0.00% |
| 21 | Affinity Asset Advisors, LLC | 640K | $9.0M | -10.5% | 1.962% | 0.46% |
| 22 | DRIEHAUS CAPITAL MANAGEMENT LLC | 635K | $8.9M | -28.4% | 1.948% | 0.07% |
| 23 | RTW INVESTMENTS, LP | 573K | $8.1M | -60.5% | 1.757% | 0.08% |
| 24 | Ikarian Capital, LLC | 512K | $7.2M | +70.8% | 1.570% | 0.58% |
| 25 | Opaleye Management Inc. | 428K | $6.0M | 0.0% | 1.311% | 0.79% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in JBIO — a direct measure of their conviction.
Filings activity in JBIO during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new JBIO position in Q1 2026
Institutions that fully closed their JBIO position in Q1 2026
4 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 119 | +13% | 100.91% | +1.82 pp | $715M | +1.8% |
| Q4 2025 | 105 | +35% | 99.09% | +60.52 pp | $702M | +157% |
| Q3 2025 | 78 | +6.8% | 38.57% | 5.57 pp | $273M | 13% |
| Q2 2025 | 73 | — | 44.14% | — | $313M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
No recent Form 4 insider transactions on file for JBIO.
Quick answers to the most common questions about buying JBIO stock.
Based on Q1 2026 13F filings, institutional ownership of Jade Biosciences, Inc. stands at 100.9%, held across 119 reporting institutions.
FMR LLC is the largest reported institutional holder of JBIO, with approximately 7,085,423 shares worth $0.10B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of JBIO.
Our composite Smart Money Score for JBIO is 50 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
29 institutions opened new positions in JBIO during Q1 2026, while 15 fully exited. 31 added to existing positions and 56 trimmed.
JBIO institutional ownership rose by 1.82 percentage points quarter-over-quarter, with a net change of — holders.
The top 10 institutions account for 65.5% of all reported 13F value in JBIO, and the top 25 account for 90.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.