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LIXT logoLixte Biotechnology Holdings, Inc.(LIXT)Earnings, Financials & Key Ratios

LIXT•NASDAQ
$4.40
$25M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutLixte Biotechnology Holdings, Inc. operates as a drug discovery company that uses biomarker technology to identify enzyme targets related with serious common diseases and designs novel compounds to attack those targets. The company primarily focuses on inhibitors of protein phosphatases that are used alone and in combination with cytotoxic agents and/or x-ray and immune checkpoint blockers; and encompasses two major categories of compounds at various stages of pre-clinical and clinical development. It develops two series of pharmacologically active drugs, which include the LB-100 series that consists of novel structures for the treatment of cancers, and vascular and metabolic diseases; and LB-200 series to treat chronic hereditary diseases, such as Gaucher's disease, as well as cancer and neurodegenerative diseases. Lixte Biotechnology Holdings, Inc. has a clinical trial research agreement with the Moffitt Cancer Center and Research Institute Hospital Inc.; collaboration agreement for an investigator-initiated clinical trial with the Spanish Sarcoma Group, as well as Netherlands Cancer Institute and Oncode Institute. The company was founded in 2005 and is based in Pasadena, California.Show more
  • Revenue$0
  • EBITDA-$4M+29.6%
  • Net Income-$4M+29.5%
  • EPS (Diluted)-1.59+40.2%
  • ROE-148.73%-33.9%
Technical→

LIXT Key Insights

Lixte Biotechnology Holdings, Inc. (LIXT) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Shares diluted 17.4% in last year
  • ✗Expensive at 12.0x book value
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

LIXT Price & Volume

Lixte Biotechnology Holdings, Inc. (LIXT) stock price & volume — 10-year historical chart

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LIXT Growth Metrics

Lixte Biotechnology Holdings, Inc. (LIXT) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-3.33%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM33.71%

Return on Capital

10 Years-279.49%
5 Years-122.2%
3 Years-128.71%
Last Year-148.19%

LIXT Peer Comparison

Lixte Biotechnology Holdings, Inc. (LIXT) competitors in Drug Discovery and Antibody Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ONCY logoONCYOncolytics Biotech Inc.Direct Competitor99M0.92-3.05-7.55%0.18
CASI logoCASICASI Pharmaceuticals, Inc.Direct Competitor2.33M0.15-0.06-15.77%-183.93%-301.8%11.96
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.67B85.09-8.75-43.89%-192.87%-356.81%0.95
IMVT logoIMVTImmunovant, Inc.Product Competitor5.83B28.67-10.50-47.07%0.00
AGIO logoAGIOAgios Pharmaceuticals, Inc.Product Competitor1.6B26.98-3.7948.03%-6.4%-34.11%0.05
MGNX logoMGNXMacroGenics, Inc.Product Competitor190.59M3.01-2.550.78%-49.91%-120.2%0.66
AGEN logoAGENAgenus Inc.Product Competitor137.4M3.89-1144.1210.37%0.1%
CRIS logoCRISCuris, Inc.Product Competitor81.2M0.62-1.06-13.43%-80.29%-138.81%0.30

Compare LIXT vs Peers

Lixte Biotechnology Holdings, Inc. (LIXT) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ONCY

Most directly comparable listed peer for LIXT.

Scale Benchmark

vs IQV

Larger-name benchmark to compare LIXT against a more recognizable public peer.

Peer Set

Compare Top 5

vs ONCY, CASI, NKTR, IMVT

LIXT Income Statement

Lixte Biotechnology Holdings, Inc. (LIXT) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue0000000000
Revenue Growth %-100%---------
Cost of Goods Sold0000000000
COGS % of Revenue----------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %----------
Gross Profit Growth %-100%---------
Operating Expenses2.13M1.81M2.14M2.49M3.27M6.72M6.31M5.09M3.57M3.9M
OpEx % of Revenue----------
Selling, General & Admin833.78K1.34M2.1M1.67M2.04M4.98M4.96M4.19M2.85M3.66M
SG&A % of Revenue----------
Research & Development1.3M467.26K40.7K820.91K1.22M1.74M1.35M898.1K726.23K237.63K
R&D % of Revenue----------
Other Operating Expenses0000000000
Operating Income
-2.13M▲ 0%
-1.81M▲ 15.2%
-2.14M▼ 18.1%
-2.49M▼ 16.5%
-3.27M▼ 31.2%
-6.72M▼ 105.7%
-6.31M▲ 6.1%
-5.09M▲ 19.3%
-3.57M▲ 29.8%
-3.9M▲ 0%
Operating Margin %----------
Operating Income Growth %19.32%15.23%-18.14%-16.46%-31.18%-105.74%6.09%19.35%29.81%-
EBITDA000-2.44M0-6.72M-6.3M-5.07M-3.57M-2.8M
EBITDA Margin %----------
EBITDA Growth %100%---100%-6.21%19.56%29.61%5.13%
D&A (Non-Cash Add-back)2.13M1.81M2.14M03.27M00001.32M
EBIT-2.13M-1.81M-2.13M-2.44M-3.27M-6.72M-6.3M-5.07M-3.57M-4.12M
Net Interest Income00049.72K1.56K-6.79K2.32K1.25K7.05K-4.08K
Interest Income1831.38K4.92K49.72K5.23K62611.2K1.25K7.05K5.75K
Interest Expense1831.38K4.92K03.67K7.41K8.88K009.83K
Other Income/Expense1831.38K4.92K49.72K1.56K-7.95K-1.05K3.21K-13.18K-237.09K
Pretax Income
-2.13M▲ 0%
-1.81M▲ 15.3%
-2.13M▼ 18.0%
-2.44M▼ 14.4%
-3.26M▼ 33.8%
-6.73M▼ 106.1%
-6.31M▲ 6.2%
-5.09M▲ 19.4%
-3.59M▲ 29.5%
-4.13M▲ 0%
Pretax Margin %----------
Income Tax-2.13K-1.81K-9.85K0000000
Effective Tax Rate %0.1%0.1%0.46%0%0%0%0%0%0%0%
Net Income
-2.13M▲ 0%
-1.81M▲ 15.3%
-2.13M▼ 18.0%
-2.44M▼ 14.4%
-3.26M▼ 33.8%
-6.73M▼ 106.1%
-6.31M▲ 6.2%
-5.09M▲ 19.4%
-3.59M▲ 29.5%
-4.13M▲ 0%
Net Margin %----------
Net Income Growth %25.15%15.29%-17.96%-14.4%-33.79%-106.08%6.18%19.41%29.51%-3.33%
Net Income (Continuing)-2.13M-1.81M-2.13M-2.44M-3.26M-6.73M-6.31M-5.09M-3.59M-4.13M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-2.68▲ 0%
-1.94▲ 27.6%
-2.18▼ 12.4%
-2.20▼ 0.9%
-2.89▼ 31.4%
-5.00▼ 73.0%
-4.00▲ 20.0%
-2.66▲ 33.5%
-1.59▲ 40.2%
-0.67▲ 0%
EPS Growth %26.78%27.61%-12.37%-0.92%-31.36%-73.01%20%33.5%40.23%33.71%
EPS (Basic)-2.68-1.94-2.18-2.20-2.89-5.00-4.00-2.66-1.59-
Diluted Shares Outstanding797.93K930.29K979.93K1.12M1.13M1.35M1.58M1.92M2.25M6.17M
Basic Shares Outstanding797K930K979.93K1.12M1.13M1.35M1.58M1.91M2.25M6.17M
Dividend Payout Ratio----------

LIXT Balance Sheet

Lixte Biotechnology Holdings, Inc. (LIXT) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets433.41K1.37M4.33M2.67M5.23M5.09M5.56M4.31M1.04M5.43M
Cash & Short-Term Investments199.93K1.31M4.27M2.6M5.07M4.82M5.35M4.2M1.04M5.34M
Cash Only199.93K1.31M4.27M2.6M5.07M4.82M5.35M4.2M1.04M2.89M
Short-Term Investments0000000002.45M
Accounts Receivable00014.37K000000
Days Sales Outstanding----------
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets062.32K61.43K24.29K15K150.24K00-106.55K0
Total Non-Current Assets002.29K076.9K000106.55K0
Property, Plant & Equipment0000000000
Fixed Asset Turnover----------
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments0000000000
Other Non-Current Assets002.29K076.9K000106.55K198.83K
Total Assets
433.41K▲ 0%
1.37M▲ 215.7%
4.34M▲ 217.0%
2.67M▼ 38.4%
5.23M▲ 95.7%
5.09M▼ 2.6%
5.56M▲ 9.2%
4.31M▼ 22.5%
1.15M▼ 73.4%
5.43M▲ 0%
Asset Turnover---------0.00x
Asset Growth %-27.52%215.65%217%-38.39%95.67%-2.59%9.18%-22.52%-73.41%33.73%
Total Current Liabilities218.65K373.02K210.91K237.9K216.52K302.93K395.76K313.86K318.28K521.42K
Accounts Payable159.59K312.03K195.21K143.55K190.29K193.47K183.75K120.51K83.21K235.9K
Days Payables Outstanding----------
Short-Term Debt0000000000
Deferred Revenue (Current)59.06K60.99K15.7K94.35K15.77K0165.02K157.1K235.08K969K
Other Current Liabilities060.99K00076.96K00050.37K
Current Ratio1.98x3.67x20.55x11.23x24.15x16.81x14.05x13.73x3.26x3.26x
Quick Ratio1.98x3.67x20.55x11.23x24.15x16.81x14.05x13.73x3.26x3.26x
Cash Conversion Cycle----------
Total Non-Current Liabilities0000000000
Long-Term Debt0000000000
Capital Lease Obligations0000000000
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities0000000000
Total Liabilities218.65K373.02K210.91K237.9K216.52K302.93K395.76K313.86K318.28K521.42K
Total Debt0000000000
Net Debt-199.93K-1.31M-4.27M-2.6M-5.07M-4.82M-5.35M-4.2M-1.04M-2.89M
Debt / Equity---------0.00x
Debt / EBITDA----------0.00x
Net Debt / EBITDA---------1.03x
Interest Coverage-11666.20x-1316.21x-434.30x--889.07x-906.45x-711.15x---419.37x
Total Equity
214.76K▲ 0%
995.04K▲ 363.3%
4.13M▲ 314.6%
2.43M▼ 41.0%
5.01M▲ 105.9%
4.79M▼ 4.4%
5.17M▲ 7.8%
3.99M▼ 22.7%
827.22K▼ 79.3%
4.91M▲ 0%
Equity Growth %-31.24%363.33%314.64%-41%105.9%-4.42%7.83%-22.66%-79.29%46.15%
Book Value per Share0.271.074.212.184.443.563.262.080.370.80
Total Shareholders' Equity214.76K995.04K4.13M2.43M5.01M4.79M5.17M3.99M827.22K4.91M
Common Stock4.79K5.8K6.7K6.7K1.24K1.37K166225225570
Retained Earnings-20.71M-22.52M-24.65M-27.09M-30.35M-37.08M-43.39M-48.48M-52.07M-55.53M
Treasury Stock0000000000
Accumulated OCI0000000000
Minority Interest0000000000

LIXT Cash Flow Statement

Lixte Biotechnology Holdings, Inc. (LIXT) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations-1.68M-1.41M-1.51M-1.67M-2.13M-4.14M-4.61M-4.29M-3.16M-3.16M
Operating CF Margin %----------
Operating CF Growth %23.09%15.81%-7%-10.79%-27.31%-94.37%-11.32%6.91%26.29%105.31%
Net Income-2.13M-1.81M-2.13M-2.44M-3.26M-6.73M-6.31M-5.09M-3.59M-4.13M
Depreciation & Amortization0000000000
Stock-Based Compensation287.16K70.69K785.61K748.65K1.25M2.6M1.55M773.2K418.42K1.27M
Deferred Taxes0000000000
Other Non-Cash Items87.16K-81.74K902.43K000000182.89K
Working Capital Changes170.13K325.54K-163.52K17.54K-117.88K-13.44K154.76K20.56K3.01K52K
Change in Receivables200K00-14.37K14.37K00000
Change in Inventory35.12K0014.37K000000
Change in Payables519152.44K-116.82K-51.66K46.74K35.67K2.32K0-73.55K95.66K
Cash from Investing104.09K00000000-2.64M
Capital Expenditures0000000000
CapEx % of Revenue----------
Acquisitions0000000000
Investments----------
Other Investing104000000000
Cash from Financing1.75M2.52M4.48M04.6M3.9M5.14M3.14M06.47M
Debt Issued (Net)0000000000
Equity Issued (Net)1.75M2.5M4.5M04.6M3.69M5.14M3.14M06.47M
Dividends Paid-2K000000000
Share Repurchases0000000000
Other Financing018K-21.7K00207.63K06.32K00
Net Change in Cash
174.65K▲ 0%
1.11M▲ 533.2%
2.97M▲ 168.3%
-1.67M▼ 156.4%
2.47M▲ 247.6%
-245.52K▼ 109.9%
529.65K▲ 315.7%
-1.15M▼ 317.1%
-3.16M▼ 175.2%
1.25M▲ 0%
Free Cash Flow
-1.68M▲ 0%
-1.41M▲ 15.8%
-1.51M▼ 7.0%
-1.67M▼ 10.8%
-2.13M▼ 27.3%
-4.14M▼ 94.4%
-4.61M▼ 11.3%
-4.29M▲ 6.9%
-3.16M▲ 26.3%
-2.58M▲ 0%
FCF Margin %----------
FCF Growth %23.09%15.81%-7%-10.79%-27.31%-94.37%-11.32%6.91%26.29%25.57%
FCF per Share-2.10-1.52-1.54-1.50-1.89-3.07-2.92-2.24-1.41-1.41
FCF Conversion (FCF/Net Income)0.79x0.78x0.71x0.69x0.65x0.62x0.73x0.84x0.88x0.62x
Interest Paid00003.67K7.41K016.23K04.43K
Taxes Paid0000000000

LIXT Key Ratios

Lixte Biotechnology Holdings, Inc. (LIXT) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)-810%-298.96%-83.31%-74.4%-87.69%-137.28%-126.81%-111.07%-148.73%-219%
Return on Invested Capital (ROIC)-1060.8%---------865.06%
Debt / Equity---------0.00x
Interest Coverage-11666.20x-1316.21x-434.30x--889.07x-906.45x-711.15x---419.37x
FCF Conversion0.79x0.78x0.71x0.69x0.65x0.62x0.73x0.84x0.88x0.62x
Revenue Growth-100%---------

LIXT Frequently Asked Questions

Lixte Biotechnology Holdings, Inc. (LIXT) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Lixte Biotechnology Holdings, Inc. (LIXT) grew revenue by 0.0% over the past year. Growth has been modest.

Lixte Biotechnology Holdings, Inc. (LIXT) reported a net loss of $4.1M for fiscal year 2024.

Dividend & Returns

Lixte Biotechnology Holdings, Inc. (LIXT) has a return on equity (ROE) of -148.7%. Negative ROE indicates the company is unprofitable.

Lixte Biotechnology Holdings, Inc. (LIXT) had negative free cash flow of $2.6M in fiscal year 2024, likely due to heavy capital investments.

Explore More LIXT

Lixte Biotechnology Holdings, Inc. (LIXT) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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