Lexicon Pharmaceuticals, Inc. (LXRX) Stock Price History
Historical prices from 2000 to 2026
- 1M
- +4.9%
- 3M
- +31.7%
- YTD
- +89.5%
- 1Y
- +194.2%
- 3Y
- -3.0%
- 5Y
- -14.6%
Loading 10-year price history...
LXRX Historical Performance
LXRX Annual Returns
Year-by-year price performance · 2002–2026
- 2002 annual price return
- -57.7%
- 2003 annual price return
- +14.4%
- 2004 annual price return
- +28.3%
- 2005 annual price return
- -50.7%
- 2006 annual price return
- -5.2%
- 2007 annual price return
- -17.9%
- 2008 annual price return
- -54.1%
- 2009 annual price return
- +18.1%
- 2010 annual price return
- -16.8%
- 2011 annual price return
- -14.0%
- 2012 annual price return
- +76.8%
- 2013 annual price return
- -24.4%
- 2014 annual price return
- -49.2%
- 2015 annual price return
- +106.7%
- 2016 annual price return
- +5.2%
- 2017 annual price return
- -30.4%
- 2018 annual price return
- -34.4%
- 2019 annual price return
- -39.9%
- 2020 annual price return
- -16.4%
- 2021 annual price return
- +11.9%
- 2022 annual price return
- -50.9%
- 2023 annual price return
- -23.1%
- 2024 annual price return
- -53.6%
- 2025 annual price return
- +48.0%
- 2026 annual price return
- +28.9%
LXRX Stock Price Trajectory (2000–2026)
As of June 24, 2026, Lexicon Pharmaceuticals, Inc. (LXRX) trades at $2.16, representing a +194.2% return over the past year. The stock has delivered a -54.6% total return over five years (-14.6% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $344.75 on July 21, 2000. From this peak, LXRX has corrected -99.4%, currently trading 41% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers ARDX (+70.2% 1Y), CORT (+7.5% 1Y), and INVA (+13.1% 1Y), LXRX has outperformed the peer group average. Compare LXRX vs ARDX →
LXRX Historical Price Data · from 2000
Rows 1–50 of 6,591| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-06-23 | 2.10 | 2.23 | 2.06 | 2.16 | 2.75M | +0.47% |
| 2026-06-22 | 2.00 | 2.15 | 2.00 | 2.15 | 3.02M | +6.97% |
| 2026-06-18 | 2.04 | 2.10 | 1.98 | 2.01 | 3.77M | -1.47% |
| 2026-06-17 | 1.98 | 2.09 | 1.95 | 2.04 | 2.59M | +4.62% |
| 2026-06-16 | 1.95 | 2.02 | 1.92 | 1.95 | 1.82M | -0.51% |
| 2026-06-15 | 1.95 | 1.98 | 1.92 | 1.96 | 701K | +2.08% |
| 2026-06-12 | 1.90 | 2.02 | 1.88 | 1.92 | 2.99M | +1.59% |
| 2026-06-11 | 1.88 | 1.95 | 1.84 | 1.89 | 2.04M | +0.53% |
| 2026-06-10 | 1.85 | 1.91 | 1.85 | 1.88 | 1.28M | 0.00% |
| 2026-06-09 | 1.88 | 1.93 | 1.84 | 1.88 | 1.25M | 0.00% |
| 2026-06-08 | 1.93 | 1.99 | 1.86 | 1.88 | 1.48M | -1.57% |
| 2026-06-05 | 1.88 | 1.94 | 1.87 | 1.91 | 1.73M | +0.53% |
| 2026-06-04 | 1.85 | 1.99 | 1.84 | 1.90 | 1.75M | +2.70% |
| 2026-06-03 | 1.89 | 1.93 | 1.81 | 1.85 | 2.65M | -2.12% |
| 2026-06-02 | 2.09 | 2.09 | 1.88 | 1.89 | 3.14M | -8.70% |
| 2026-06-01 | 2.16 | 2.19 | 2.07 | 2.07 | 1.83M | -5.05% |
| 2026-05-29 | 2.21 | 2.23 | 2.14 | 2.18 | 1.49M | -1.36% |
| 2026-05-28 | 2.17 | 2.27 | 2.17 | 2.21 | 1.85M | +1.84% |
| 2026-05-27 | 2.06 | 2.21 | 2.04 | 2.17 | 1.86M | +5.34% |
| 2026-05-26 | 2.21 | 2.22 | 2.04 | 2.06 | 3.07M | -4.63% |
| 2026-05-22 | 2.23 | 2.29 | 2.15 | 2.16 | 1.62M | -3.14% |
| 2026-05-21 | 2.11 | 2.25 | 2.11 | 2.23 | 1.65M | +0.90% |
| 2026-05-20 | 2.15 | 2.26 | 2.14 | 2.21 | 1.69M | +3.76% |
| 2026-05-19 | 2.06 | 2.15 | 2.04 | 2.13 | 1.62M | -0.47% |
| 2026-05-18 | 2.22 | 2.26 | 2.08 | 2.14 | 2.19M | -4.04% |
| 2026-05-15 | 2.29 | 2.32 | 2.21 | 2.23 | 2.10M | -4.29% |
| 2026-05-14 | 2.44 | 2.44 | 2.29 | 2.33 | 2.49M | -4.51% |
| 2026-05-13 | 2.41 | 2.51 | 2.34 | 2.44 | 3.29M | +1.24% |
| 2026-05-12 | 2.31 | 2.52 | 2.25 | 2.41 | 6.21M | +4.33% |
| 2026-05-11 | 2.00 | 2.47 | 2.00 | 2.31 | 13.90M | +15.50% |
| 2026-05-08 | 1.69 | 2.00 | 1.64 | 2.00 | 6.97M | +19.05% |
| 2026-05-07 | 1.65 | 1.69 | 1.52 | 1.68 | 5.02M | +5.00% |
| 2026-05-06 | 1.66 | 1.66 | 1.60 | 1.60 | 2.20M | -3.03% |
| 2026-05-05 | 1.60 | 1.65 | 1.56 | 1.65 | 1.54M | +3.13% |
| 2026-05-04 | 1.63 | 1.67 | 1.59 | 1.60 | 1.09M | -1.84% |
| 2026-05-01 | 1.59 | 1.66 | 1.57 | 1.63 | 1.39M | +1.24% |
| 2026-04-30 | 1.58 | 1.63 | 1.56 | 1.61 | 1.15M | +3.87% |
| 2026-04-29 | 1.65 | 1.65 | 1.55 | 1.55 | 1.58M | -6.63% |
| 2026-04-28 | 1.69 | 1.72 | 1.66 | 1.66 | 988K | -1.78% |
| 2026-04-27 | 1.69 | 1.76 | 1.67 | 1.69 | 1.88M | +0.60% |
| 2026-04-24 | 1.67 | 1.69 | 1.62 | 1.68 | 1.92M | 0.00% |
| 2026-04-23 | 1.83 | 1.84 | 1.67 | 1.68 | 2.18M | -7.69% |
| 2026-04-22 | 1.85 | 1.91 | 1.80 | 1.82 | 1.38M | -0.55% |
| 2026-04-21 | 1.85 | 1.89 | 1.79 | 1.83 | 1.37M | -0.54% |
| 2026-04-20 | 1.87 | 1.88 | 1.80 | 1.84 | 1.65M | -1.60% |
| 2026-04-17 | 1.87 | 1.95 | 1.85 | 1.87 | 3.13M | +1.63% |
| 2026-04-16 | 1.85 | 1.89 | 1.81 | 1.84 | 1.96M | -1.08% |
| 2026-04-15 | 1.75 | 1.86 | 1.74 | 1.86 | 2.13M | +6.29% |
| 2026-04-14 | 1.71 | 1.79 | 1.70 | 1.75 | 1.24M | +2.34% |
| 2026-04-13 | 1.70 | 1.74 | 1.69 | 1.71 | 830K | -0.58% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
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Peer Comparison
Compare growth, multiples, and margins vs sector.
LXRX — Frequently Asked Questions
Quick answers to the most common questions about buying LXRX stock.
How has LXRX stock performed recently?
LXRX returned +194.2% over the past year, beating its 5-year annualized CAGR of -14.6%. The stock trades above its 200-day moving average, confirming the uptrend.
What is LXRX's all-time high price?
Lexicon Pharmaceuticals, Inc. reached $344.75 on 2000-07-21. The 52-week high is $2.52. Current 1-year return of +194.2% places the stock closer to historical peaks.
Where can I download LXRX historical price data?
This page provides LXRX daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2000-2026, downloadable in CSV format.