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LYRA logoLyra Therapeutics, Inc. (LYRA) Earnings History

Annual and quarterly earnings data from 2018 to 2024

TTM Net Income
-$33M
Net Loss
TTM EPS
$-18.64
Diluted
YoY EPS Growth
-13.5%
Declining
Net Margin
-6090.9%
Profitability
Operating Margin-6280.8%
Gross Margin100.0%
ROE-185.0%
ROA-89.4%
Highest Annual Net Income-$6M (2018)
Highest Quarterly EPS$-0.13 (Q1 2025)
Consecutive Profitable Years0 years
Q3 2025
Net Income-$6M
EPS$-3.38
QoQ Growth+19.5%Strong

Loading earnings history...

LYRA EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

LYRA Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
2024100.0%-6280.8%-6090.9%
2023100.0%-4308.1%-4023.1%
2022100.0%-4131.0%-4055.6%
2021-10318.9%-15303.5%-15267.7%
2020---
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Lyra Therapeutics, Inc. (LYRA) Earnings Overview

As of May 8, 2026, Lyra Therapeutics, Inc. (LYRA) reported trailing twelve-month net income of -$33M, reflecting -13.5% year-over-year growth. The company earned $-18.64 per diluted share over the past four quarters, with a net profit margin of -6090.9%.

Looking at the long-term picture, LYRA's historical earnings data spans multiple years. The company achieved its highest annual net income of -$6M in fiscal 2018.

Lyra Therapeutics, Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including XNCR (-$172M net income, -73.2% margin), PRAX (-$327M net income), SINT (-$17M net income, -1678.1% margin), LYRA has room to improve margins relative to the peer group. Compare LYRA vs XNCR →

LYRA Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
LYRA logoLYRACurrent
-$33M$-18.64-6090.9%-185.0%-13.5%—
XNCR logoXNCR
-$172M$-2.29-73.2%-14.0%+65.4%
PRAX logoPRAX
-$327M$-11.31--45.8%-32.0%
SINT logoSINT
-$17M$-5.59-1678.1%-500.7%+59.4%
ARWR logoARWR
-$301M$-2.11-0.2%-0.5%+99.8%
MCRB logoMCRB
-$47M$-4.89721.9%19.6%+103.4%
Best in group
Lowest in group

LYRA Historical Earnings Data (2018–2024)

7 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2024-$93M-49.1%-$96M$-1.43-6090.9%-6280.8%
2023-$63M-13.4%-$67M$-1.26-4023.1%-4308.1%
2022-$55M-27.0%-$56M$-1.83-4055.6%-4131.0%
2021-$44M-96.7%-$44M$-3.35-15267.7%-15303.5%
2020-$22M-35.7%-$22M$-2.59--
2019-$16M-170.5%-$17M$-62.50--
2018-$6M--$7M$-0.98-484.6%-583.5%

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Compare LYRA vs DBVT

Side-by-side business, growth, and profitability comparison vs DBV Technologies S.A..

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LYRA — Frequently Asked Questions

Quick answers to the most common questions about buying LYRA stock.

Is LYRA growing earnings?

LYRA EPS fell to $-18.64, with earnings declining -13.5%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-33M.

What are LYRA's profit margins?

Lyra Therapeutics, Inc. net margin is -6090.9%, with operating margin at -6280.8%. Below-average margins reflect competitive or cost pressures.

How consistent are LYRA's earnings?

LYRA earnings data spans 2018-2024. The declining earnings trend is -13.5% YoY. Historical data enables comparison across business cycles.

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LYRA Earnings Over Time (2018–2024)

Net income and EPS trends