Lyra Therapeutics, Inc. (LYRA) Stock Price History
Historical prices from 2020 to 2026
- 1M
- —
- 3M
- +0.0%
- YTD
- -86.1%
- 1Y
- -95.9%
- 3Y
- -86.6%
- 5Y
- -74.8%
Loading 10-year price history...
LYRA Historical Performance
LYRA Annual Returns
Year-by-year price performance · 2020–2026
- 2020 annual price return
- -38.6%
- 2021 annual price return
- -61.2%
- 2022 annual price return
- -32.9%
- 2023 annual price return
- +69.6%
- 2024 annual price return
- -96.0%
- 2025 annual price return
- -71.5%
- 2026 annual price return
- -68.0%
LYRA Stock Price Trajectory (2020–2026)
As of June 23, 2026, Lyra Therapeutics, Inc. (LYRA) trades at $0.44, representing a -95.9% return over the past year. The stock has delivered a -99.9% total return over five years (-74.8% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $1,100.00 on May 1, 2020. From this peak, LYRA has corrected -100.0%, currently trading 93% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers XNCR (+51.2% 1Y), PRAX (+557.0% 1Y), and SINT (-36.1% 1Y), LYRA has underperformed the peer group average. Compare LYRA vs XNCR →
LYRA Historical Price Data · from 2020
Rows 1–50 of 1,477| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-03-18 | 0.46 | 0.48 | 0.44 | 0.44 | 78K | -11.09% |
| 2026-03-16 | 1.29 | 1.33 | 0.49 | 0.49 | 1.02M | -62.50% |
| 2026-03-13 | 1.32 | 1.34 | 1.31 | 1.32 | 3K | -1.49% |
| 2026-03-12 | 1.32 | 1.35 | 1.32 | 1.34 | 8K | +2.29% |
| 2026-03-11 | 1.31 | 1.42 | 1.27 | 1.31 | 16K | +0.77% |
| 2026-03-10 | 1.28 | 1.32 | 1.24 | 1.30 | 13K | 0.00% |
| 2026-03-09 | 1.28 | 1.30 | 1.28 | 1.30 | 9K | +4.00% |
| 2026-03-06 | 1.28 | 1.30 | 1.25 | 1.25 | 15K | -3.10% |
| 2026-03-05 | 1.28 | 1.30 | 1.21 | 1.29 | 20K | +2.38% |
| 2026-03-04 | 1.25 | 1.35 | 1.23 | 1.26 | 47K | +1.61% |
| 2026-03-03 | 1.18 | 1.27 | 1.08 | 1.24 | 83K | +4.20% |
| 2026-03-02 | 0.97 | 1.45 | 0.91 | 1.19 | 703K | +17.82% |
| 2026-02-27 | 1.13 | 1.19 | 1.00 | 1.01 | 83K | -9.82% |
| 2026-02-26 | 1.37 | 1.46 | 1.12 | 1.12 | 124K | -20.00% |
| 2026-02-25 | 1.46 | 1.48 | 1.40 | 1.40 | 6K | -4.11% |
| 2026-02-24 | 1.44 | 1.47 | 1.39 | 1.46 | 23K | +0.69% |
| 2026-02-23 | 1.46 | 1.46 | 1.43 | 1.45 | 5K | 0.00% |
| 2026-02-20 | 1.50 | 1.50 | 1.45 | 1.45 | 1 | -2.68% |
| 2026-02-19 | 1.41 | 1.52 | 1.41 | 1.49 | 11K | +6.43% |
| 2026-02-18 | 1.39 | 1.47 | 1.39 | 1.40 | 17K | +5.97% |
| 2026-02-17 | 1.45 | 1.47 | 1.31 | 1.32 | 8K | -4.96% |
| 2026-02-13 | 1.35 | 1.45 | 1.21 | 1.39 | 81K | +5.30% |
| 2026-02-12 | 1.39 | 1.40 | 1.32 | 1.32 | 29K | -3.65% |
| 2026-02-11 | 1.49 | 1.49 | 1.32 | 1.37 | 40K | -6.80% |
| 2026-02-10 | 1.54 | 1.58 | 1.47 | 1.47 | 24K | -3.29% |
| 2026-02-09 | 1.83 | 1.83 | 1.51 | 1.52 | 100K | -16.48% |
| 2026-02-06 | 1.71 | 1.90 | 1.71 | 1.82 | 21K | +2.82% |
| 2026-02-05 | 1.88 | 1.95 | 1.77 | 1.77 | 16K | -6.10% |
| 2026-02-04 | 2.00 | 2.03 | 1.82 | 1.89 | 23K | -4.80% |
| 2026-02-03 | 2.03 | 2.05 | 1.93 | 1.98 | 12K | -1.98% |
| 2026-02-02 | 1.86 | 2.04 | 1.73 | 2.02 | 90K | +13.48% |
| 2026-01-30 | 1.99 | 2.02 | 1.78 | 1.78 | 27K | -12.75% |
| 2026-01-29 | 2.04 | 2.05 | 1.86 | 2.04 | 73K | -0.49% |
| 2026-01-28 | 1.67 | 2.15 | 1.60 | 2.05 | 186K | +20.94% |
| 2026-01-27 | 1.76 | 1.80 | 1.65 | 1.70 | 58K | -2.59% |
| 2026-01-26 | 2.07 | 2.12 | 1.74 | 1.74 | 80K | -15.12% |
| 2026-01-24 | 2.31 | 2.31 | 1.80 | 2.05 | 56K | 0.00% |
| 2026-01-23 | 2.24 | 2.31 | 1.80 | 2.05 | 89K | -6.82% |
| 2026-01-22 | 2.29 | 2.39 | 2.18 | 2.20 | 43K | -2.22% |
| 2026-01-21 | 2.41 | 2.44 | 2.20 | 2.25 | 61K | -3.85% |
| 2026-01-20 | 1.97 | 2.58 | 1.94 | 2.34 | 338K | +17.59% |
| 2026-01-16 | 1.99 | 2.02 | 1.89 | 1.99 | 42K | +2.31% |
| 2026-01-15 | 1.89 | 1.97 | 1.89 | 1.95 | 32K | +2.91% |
| 2026-01-14 | 1.95 | 1.97 | 1.85 | 1.89 | 32K | -5.03% |
| 2026-01-13 | 1.96 | 2.06 | 1.78 | 1.99 | 248K | -3.40% |
| 2026-01-12 | 2.00 | 2.27 | 1.63 | 2.06 | 1.39M | -45.31% |
| 2026-01-09 | 3.73 | 3.94 | 3.73 | 3.77 | 14K | -0.87% |
| 2026-01-08 | 3.62 | 3.80 | 3.53 | 3.80 | 7K | +5.26% |
| 2026-01-07 | 3.35 | 3.62 | 3.34 | 3.61 | 23K | +7.44% |
| 2026-01-06 | 3.38 | 3.46 | 3.29 | 3.36 | 15K | -0.59% |
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
LYRA — Frequently Asked Questions
Quick answers to the most common questions about buying LYRA stock.
How has LYRA stock performed recently?
LYRA declined -95.9% over the past year, below its 5-year annualized CAGR of -74.8%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is LYRA's all-time high price?
Lyra Therapeutics, Inc. reached $1100.00 on 2020-05-01. The 52-week high is $14.88. Current 1-year return of -95.9% places the stock further from historical peaks.
Where can I download LYRA historical price data?
This page provides LYRA daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.