Lyra Therapeutics, Inc. (LYRA) Stock Price History
Historical prices from 2020 to 2026
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LYRA Historical Performance
Short-Term Returns
LYRA Stock Price Trajectory (2020–2026)
As of May 8, 2026, Lyra Therapeutics, Inc. (LYRA) trades at $0.44, representing a -90.7% return over the past year. The stock has delivered a -99.9% total return over five years (-74.4% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $1,100.00 on May 1, 2020. From this peak, LYRA has corrected -100.0%, currently trading 93% below its 200-day moving average, suggesting potential weakness.
When compared to Healthcare sector peers XNCR (+46.3% 1Y), PRAX (+767.1% 1Y), and SINT (-5.1% 1Y), LYRA has underperformed the peer group average. Compare LYRA vs XNCR →
LYRA Historical Price Data (2025–2026)
Showing 30 of 1,477 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-03-18 | 0.46 | 0.48 | 0.44 | 0.44 | 78K | -11.09% |
| 2026-03-16 | 1.29 | 1.33 | 0.49 | 0.49 | 1.02M | -62.50% |
| 2026-03-13 | 1.32 | 1.34 | 1.31 | 1.32 | 3K | -1.49% |
| 2026-03-12 | 1.32 | 1.35 | 1.32 | 1.34 | 8K | +2.29% |
| 2026-03-11 | 1.31 | 1.42 | 1.27 | 1.31 | 16K | +0.77% |
| 2026-03-10 | 1.28 | 1.32 | 1.24 | 1.30 | 13K | 0.00% |
| 2026-03-09 | 1.28 | 1.30 | 1.28 | 1.30 | 9K | +4.00% |
| 2026-03-06 | 1.28 | 1.30 | 1.25 | 1.25 | 15K | -3.10% |
| 2026-03-05 | 1.28 | 1.30 | 1.21 | 1.29 | 20K | +2.38% |
| 2026-03-04 | 1.25 | 1.35 | 1.23 | 1.26 | 47K | +1.61% |
| 2026-03-03 | 1.18 | 1.27 | 1.08 | 1.24 | 83K | +4.20% |
| 2026-03-02 | 0.97 | 1.45 | 0.91 | 1.19 | 703K | +17.82% |
| 2026-02-27 | 1.13 | 1.19 | 1.00 | 1.01 | 83K | -9.82% |
| 2026-02-26 | 1.37 | 1.46 | 1.12 | 1.12 | 124K | -20.00% |
| 2026-02-25 | 1.46 | 1.48 | 1.40 | 1.40 | 6K | -4.11% |
| 2026-02-24 | 1.44 | 1.47 | 1.39 | 1.46 | 23K | +0.69% |
| 2026-02-23 | 1.46 | 1.46 | 1.43 | 1.45 | 5K | 0.00% |
| 2026-02-20 | 1.50 | 1.50 | 1.45 | 1.45 | 1 | -2.68% |
| 2026-02-19 | 1.41 | 1.52 | 1.41 | 1.49 | 11K | +6.43% |
| 2026-02-18 | 1.39 | 1.47 | 1.39 | 1.40 | 17K | +5.97% |
| 2026-02-17 | 1.45 | 1.47 | 1.31 | 1.32 | 8K | -4.96% |
| 2026-02-13 | 1.35 | 1.45 | 1.21 | 1.39 | 81K | +5.30% |
| 2026-02-12 | 1.39 | 1.40 | 1.32 | 1.32 | 29K | -3.65% |
| 2026-02-11 | 1.49 | 1.49 | 1.32 | 1.37 | 40K | -6.80% |
| 2026-02-10 | 1.54 | 1.58 | 1.47 | 1.47 | 24K | -3.29% |
| 2026-02-09 | 1.83 | 1.83 | 1.51 | 1.52 | 100K | -16.48% |
| 2026-02-06 | 1.71 | 1.90 | 1.71 | 1.82 | 21K | +2.82% |
| 2026-02-05 | 1.88 | 1.95 | 1.77 | 1.77 | 16K | -6.10% |
| 2026-02-04 | 2.00 | 2.03 | 1.82 | 1.89 | 23K | -4.80% |
| 2026-02-03 | 2.03 | 2.05 | 1.93 | 1.98 | 12K | -1.98% |
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Start ComparisonLYRA — Frequently Asked Questions
Quick answers to the most common questions about buying LYRA stock.
How has LYRA stock performed recently?
LYRA declined -90.7% over the past year, below its 5-year annualized CAGR of -74.4%. The stock trades below its 200-day moving average, reflecting the downtrend.
What is LYRA's all-time high price?
Lyra Therapeutics, Inc. reached $1100.00 on 2020-05-01. The 52-week high is $37.50. Current 1-year return of -90.7% places the stock further from historical peaks.
Where can I download LYRA historical price data?
This page provides LYRA daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2020-2026, downloadable in CSV format.