MacroGenics, Inc. (MGNX) P/E Ratio History
Deep ValueTrading at -3.5x · 0th percentile of 5-year range · Significant discount to historical valuation · Data 2013–2023
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P/E Ratio Analysis
As of June 21, 2026, MacroGenics, Inc. (MGNX) trades at a price-to-earnings ratio of -3.5x, with a stock price of $4.13 and trailing twelve-month earnings per share of $-1.11.
The current P/E is 100% below its 5-year average of 844.8x. Over the past five years, MGNX's P/E has ranged from a low of 5.9x to a high of 2016.7x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 22.1x, MGNX trades at a 116% discount to its sector peers. The sector includes 234 companies with P/E ratios ranging from 0.0x to 197.0x.
Relative to the broader market, MGNX trades at a notable discount to the S&P 500 median P/E of 24.4x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our MGNX DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
MGNX Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
MGNX P/E vs Peers
Oncology Therapeutics Developers peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $383B | 91.4 | - | -1% | |
| $63B | 14.7Lowest | 2.32Best | +8% | |
| $182B | 23.7 | 8.07 | +88%Best |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
MGNX Historical P/E Data (2013–2023)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2023 Q3 | Sep 30 2023 | $4.66 | $0.79 | 5.9x | -99% |
| FY2023 Q2 | Jun 30 2023 | $5.35 | $0.11 | 48.6x | -94% |
| FY2015 Q1 | - | $31.37 | $0.19 | 165.1x | -80% |
| FY2014 Q1 | Mar 31 2014 | $27.83 | $0.01 | 2016.7x | +139% |
| FY2013 Q4 | - | $27.43 | $0.01 | 1987.7x | +135% |
Average P/E for displayed period: 844.8x
Intrinsic Valuation
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Historical Returns
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Peer Comparison
Compare growth, multiples, and margins vs sector.
MGNX — Frequently Asked Questions
Quick answers to the most common questions about buying MGNX stock.
What is MGNX's P/E ratio?
MacroGenics, Inc. (MGNX) trailing twelve-month P/E ratio is -3.5x, based on TTM diluted EPS of $-1.11. The 5-year average P/E is 844.8x and the historical range spans 5.9x to 2016.7x.
Is MGNX stock overvalued or undervalued?
MGNX trades at -3.5x P/E, below its 5-year average of 844.8x. At the 0th percentile of its historical range (5.9x–2016.7x), the stock is priced at a discount to its own history.
Is MGNX stock expensive?
No, MGNX is not expensive on a historical basis. The current P/E of -3.5x is below the 5-year average of 844.8x and sits at the 0th percentile of its valuation range.
What is MGNX's historical P/E range?
Over the past 5 years, MGNX's P/E ratio has ranged from 5.9x to 2016.7x, with a median of 165.1x and an average of 844.8x. The current P/E of -3.5x places the stock at the 0th percentile of this range. Full historical data spans 2013–2023.
How does MGNX's P/E compare to the S&P 500?
MGNX trades at -3.5x P/E versus the S&P 500 median of 24.4x. The 114% discount to the market suggests lower growth expectations or perceived higher risk.
How does MGNX's valuation compare to Healthcare peers?
MacroGenics, Inc. P/E of -3.5x compares to the Healthcare sector median of 22.1x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is MGNX's PEG ratio?
MGNX PEG ratio is N/A, based on a P/E of -3.5x and EPS growth of -10.3%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is MGNX's earnings yield?
MGNX earnings yield is N/A, the inverse of its -3.5x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.