Cash flow turned sharply negative, with free cash flow swinging from +$39.5M in 2025Q3 to -$273.7M in 2026Q2, reflecting a -155.3% FCF margin, while stock-based compensation of $66.8M exceeded the operating loss, obscuring true cash burn.
Mirum Pharmaceuticals, Inc. (MIRM) cash flow statement — 8-year operating, investing & financing cash flows
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 |
|---|
| Cash from Operations | -456.03M | 55.83M | 10.32M | -70.94M | -120.14M | -132.76M | -89.08M | -39.36M | -373K |
| Operating CF Margin % | - | 10.71% | 3.06% | -38.07% | -155.9% | -693.69% | - | - | - |
| Operating CF Growth % | -12817.48% | 440.7% | 114.55% | 40.95% | 9.51% | -49.04% | -126.3% | -10452.82% | - |
| Net Income | -860.21M | -23.36M | -87.94M | -163.41M | -135.66M | -83.99M | -103.27M | -52.55M | -17.35M |
| Depreciation & Amortization | 32.82M | 24.24M | 23.63M | 10.83M | 3.68M | 975K | 623K | 324K | 0 |
| Stock-Based Compensation | 140.13M | 71.42M | 48.44M | 35.02M | 27.01M | 23.09M | 12.55M | 6.07M | 51K |
| Deferred Taxes | 0 | 0 | 0 | 0 | -6.58M | 595K | 72K | 0 | 0 |
| Other Non-Cash Items | 859.03M | 3.24M | 3.6M | 69.26M | 12.47M | -90.41M | 335K | -326K | 12.09M |
| Working Capital Changes | 162.36M | -19.71M | 22.59M | -22.64M | -21.05M | 16.98M | 611K | 7.12M | 2.44M |
| Change in Receivables | -61.67M | -48.05M | -11.43M | -43.97M | -20.73M | 0 | 0 | 0 | 0 |
| Change in Inventory | -6.89M | -8.45M | -3.17M | -4.39M | -3.45M | -495K | 0 | 0 | 0 |
| Change in Payables | 123.22M | 50.1M | 40.31M | 30.78M | 7.64M | 22.66M | 3.68M | 10.06M | 2.45M |
| Cash from Investing | -184.35M | -23.95M | -90.13M | -107.2M | 7.7M | 48.55M | 37.87M | -127.78M | -7.5M |
| Capital Expenditures | -12.14M | -954K | -993K | -109K | -278K | -19.02M | -225K | -281K | -7.5M |
| CapEx % of Revenue | 1.96% | 0.18% | 0.29% | 0.06% | 0.36% | 99.4% | - | - | - |
| Acquisitions | 0 | 0 | 0 | -212.76M | -7.98M | -19M | -38.1M | 127.5M | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -35M | 0 | -20M | -20M | 7.98M | 127M | 38.1M | -127.5M | -11.25M |
| Cash from Financing | 776.69M | 40.14M | 17.7M | 336.6M | 109.09M | 73.47M | 181.29M | 127.18M | 59.84M |
| Debt Issued (Net) | 198.07M | 0 | 0 | 305.3M | 0 | 0 | 0 | 0 | 50K |
| Equity Issued (Net) | 578.62M | 40.14M | 17.7M | 216.68M | 107.37M | 6.91M | 131.87M | 127.18M | 59.79M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 0 | 0 | 0 | -185.39M | 1.72M | 66.55M | 49.42M | 0 | 0 |
| Net Change in Cash | 132.08M | 75.24M | -63.4M | 158.32M | -3.34M | -10.75M | 130.12M | -39.99M | 51.96M |
| Free Cash Flow | -458.17M | 54.87M | 9.33M | -91.05M | -120.41M | -151.78M | -89.3M | -39.64M | -7.87M |
| FCF Margin % | -74.13% | 10.53% | 2.77% | -48.85% | -156.26% | -793.09% | - | - | - |
| FCF Growth % | -33269.85% | 488.01% | 110.25% | 24.38% | 20.67% | -69.97% | -125.26% | -403.53% | - |
| FCF per Share | -7.23 | 1.09 | 0.20 | -2.23 | -3.54 | -5.01 | -3.54 | -1.72 | -0.34 |
| FCF Conversion (FCF/Net Income) | 0.53x | -2.39x | -0.12x | 0.43x | 0.89x | 1.58x | 0.86x | 0.75x | 0.02x |
| Interest Paid | 0 | 0 | 12.65M | 6.82M | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 1M | 125K | 0 | 0 | 11K | 21K | 0 |
Quick answers to the most common questions about buying MIRM stock.
Mirum Pharmaceuticals, Inc. (MIRM) generated $55.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
Mirum Pharmaceuticals, Inc. (MIRM) generated $54.9M in free cash flow in 2025. Free cash flow is the cash left over after capital expenditures, which can be used to pay dividends, repurchase shares, or pay down debt.
Mirum Pharmaceuticals, Inc. (MIRM) spent $1.0M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
Key Metrics
Top Statement Risk
SBC dilution and cash burn
Metrics are mathematically derived from official filings.
Earnings Quality Masked by Non-Cash Charges
In 2026Q2, operating cash flow of -$273.0M versus net income of -$67.2M implies a 4.06x OCF/NI ratio, per the cash flow statement, suggesting large non-cash adjustments and working capital swings distort earnings quality.
The massive divergence in 2026Q2 is driven by a $62.0M working capital source and $66.8M in SBC, but the $273.0M operating cash outflow far exceeds the net loss, indicating that cash consumption is significantly higher than accounting losses suggest. In contrast, 2025Q3 showed a positive OCF of $39.7M against a small net profit, highlighting quarter-to-quarter volatility. Investors should monitor whether the 2026Q1 net loss of -$790.2M, likely a non-cash impairment, is a one-time event or signals recurring cash burn.
Free Cash Flow Swing Turns Sharply Negative
Free cash flow deteriorated from a positive $39.5M in 2025Q3 to -$273.7M in 2026Q2, per the cash flow data, with FCF margin collapsing from 29.7% to -155.3%, reflecting a sudden reversal in cash generation.
The trajectory shows a clear inflection point: after three quarters of positive or near-breakeven FCF in 2025, 2026Q1 and Q2 saw massive outflows, with cumulative FCF over the last two quarters at -$503.1M. This suggests that the company's commercial ramp is consuming cash faster than revenue growth can offset, possibly due to inventory builds or one-time payments. The positive FCF in 2025Q3 appears anomalous relative to the broader trend, warranting scrutiny of what drove that quarter's working capital release.
Working Capital Volatility Drives Cash Flow
Working capital changes swung from a $102.2M source in 2026Q1 to a $62.0M source in 2026Q2, per the cash flow statement, but the 2025Q4 -$14.0M use shows erratic patterns that amplify cash flow swings.
The working capital line is a major source of volatility: in 2026Q1, a $102.2M positive adjustment partially offset the operating loss, but in 2026Q2, a $62.0M source was insufficient to prevent a $273.0M outflow. This suggests that the company may be stretching payables or collecting receivables aggressively, but the inconsistency across quarters indicates a lack of stable cash conversion. Investors should assess whether these swings reflect genuine operational efficiency or timing distortions, as they materially affect reported OCF.
Minimal Capital Expenditure Signals Asset-Light Model
Capital expenditures averaged just 0.4% of revenue in 2026Q2, per the cash flow data, with quarterly capex never exceeding $10.7M, indicating a highly asset-light business model focused on commercial and R&D spend.
Capex is negligible relative to revenue, which is typical for a biotech that outsources manufacturing and relies on partnerships. The low capital intensity means that free cash flow is almost entirely driven by operating cash flow, making working capital and expense management the key levers. This also implies that the company does not require heavy fixed-asset investment to grow, but the lack of capex may limit internal manufacturing flexibility.
No Capital Returns, All Cash Absorbed by Operations
Mirum paid no dividends and made no buybacks across all ten quarters, per the cash flow data, with all available cash directed toward operating losses and pipeline investment, reflecting a reinvestment-only strategy.
The absence of shareholder returns is consistent with a growth-stage biotech that is still burning cash. However, the scale of operating cash outflows in 2026Q2 (-$273.0M) suggests that the company may need to raise external capital or draw down existing reserves to fund ongoing operations. Investors should monitor the company's cash position and financing activities, as the current burn rate is not sustainable without additional funding.
What the Cash Flow Statement Obscures
Stock-based compensation of $66.8M in 2026Q2, per the cash flow data, exceeds the operating loss, and the $790.2M net loss in 2026Q1 likely includes non-cash impairments, obscuring the true cash burn rate.
The cash flow statement adjusts for SBC, but the magnitude of SBC relative to revenue (37.9% in 2026Q2) suggests that reported operating losses understate the economic cost to shareholders. Additionally, the 2026Q1 net loss of -$790.2M is not reflected in operating cash flow, implying a large non-cash charge that may be a one-time impairment. Investors should adjust for these items to assess the underlying cash-generating ability of the commercial portfolio, as the reported figures may overstate or understate the company's true cash position.