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MNPRMonopar Therapeutics Inc.
$81.77$548M
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  3. Financial Ratios

Monopar Therapeutics Inc. (MNPR) Financial Ratios

11 years of historical data (2015–2025) · Healthcare · Biotechnology

View Quarterly Ratios →

P/E Ratio
-44.20
—
5yr avg: N/A
050%ile100
View P/E History →
EV/EBITDA
N/A
—
5yr avg: N/A
P/FCF
N/A
—
5yr avg: N/A
P/B Ratio
↓
4.40
↓-42% vs avg
5yr avg: 7.60
014%ile100
30Y Low3.5·High69.6
ROE
↑
-14.2%
↓+76% vs avg
5yr avg: -59.6%
0100%ile100
30Y Low-266%·High-14%
Debt/EBITDA
N/A
—
5yr avg: N/A

Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.

MNPR Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

Monopar Therapeutics Inc. currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Market Cap$548M$484M$253M$25M$151M$200M$335M$879M———
Enterprise Value$486M$422M$207M$17M$143M$180M$319M$866M———
P/E Ratio →-44.20——————————
P/S Ratio———————————
P/B Ratio4.403.514.594.4114.9410.5721.3769.59———
P/FCF———————————
P/OCF———————————

P/E links to full P/E history page with 30-year chart

MNPR EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
EV / Revenue———————————
EV / EBITDA———————————
EV / EBIT———————————
EV / FCF———————————

MNPR Profitability

Margins and return-on-capital ratios measuring operating efficiency

A negative ROE of -14.2% indicates the company is currently destroying shareholder equity.

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Gross Margin———————————
Operating Margin———————————
Net Profit Margin———————————

Return on Capital

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
ROE-14.2%-14.2%-51.4%-107.2%-72.4%-52.6%-44.5%-43.2%-39.0%-265.9%-42.5%
ROA-13.6%-13.6%-46.1%-81.7%-62.3%-48.7%-41.7%-40.9%-37.4%-258.1%-41.4%
ROIC-29.4%-29.4%-321.4%-5671.9%-2878.6%———-769.7%-1784.1%-118.7%
ROCE-17.3%-17.3%-53.3%-112.6%-72.6%-52.7%-46.0%-44.2%-41.2%-266.7%-42.7%

MNPR Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

The company holds a net cash position — cash of $62M exceeds total debt of $154920, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns.

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Debt / Equity0.000.00——0.00——————
Debt / EBITDA———————————
Net Debt / Equity—-0.45-0.83-1.30-0.81-1.07-1.07-1.05-1.00-0.93-0.73
Net Debt / EBITDA———————————
Debt / FCF———————————
Interest Coverage————————-32.27-343.07-163.83

Net cash position: cash ($62M) exceeds total debt ($154920)

MNPR Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

Monopar Therapeutics Inc.'s current ratio of 51.35x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has improved from 4.17x to 51.35x over the past 3 years.

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Current Ratio51.3551.3511.474.174.2112.9814.2818.2718.3229.2832.48
Quick Ratio51.3551.3511.474.174.2112.9814.2818.2718.3229.2832.48
Cash Ratio51.3351.3311.464.134.1912.8514.2218.2517.2528.8032.13
Asset Turnover———————————
Inventory Turnover———————————
Days Sales Outstanding———————————

MNPR Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Monopar Therapeutics Inc. returns 6.4% to shareholders annually primarily through share buybacks.

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2025FY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016
Earnings Yield———————————
FCF Yield———————————
Buyback Yield6.4%7.2%0.0%0.0%0.0%0.0%0.0%0.0%———
Total Shareholder Yield6.4%7.2%0.0%0.0%0.0%0.0%0.0%0.0%———
Shares Outstanding—$7M$11M$15M$13M$12M$11M$11M$10M$10M$10M

Peer Comparison

Compare MNPR with 10 similar companies in its peer group

CompanyMarket CapP/EEV/EBITDAP/FCFGross MarginOp MarginROEROICDebt/EBITDA
MNPR logoMNPRYou$548M-44.2————-14.2%-29.4%—
CLDX logoCLDX$2B-8.5——100.0%-19160.0%-40.6%-35.2%—
IMVT logoIMVT$8B-13.6————-64.8%——
TPVG logoTPVG$192M3.98.5—83.5%77.9%14.1%7.2%6.2
NKTR logoNKTR$1B-6.9——100.0%-236.8%-217.9%-57.2%—
ADXN logoADXN$5M-0.8——100.0%-9390.8%-93.2%-44.3%—
CASI logoCASI$2M-0.1——39.1%-138.8%-301.8%-153.0%—
AGEN logoAGEN$128M-902.9——29.6%-18.0%———
SNDX logoSNDX$2B-6.0——96.0%-158.4%-161.8%-54.2%—
KPTI logoKPTI$82M-0.5——95.9%-62.1%———
IQV logoIQV$29B21.812.614.226.3%14.0%21.4%8.7%4.7
Healthcare Median—22.014.118.763.6%-4.8%-32.4%-11.2%3.2

Peer selection based on competitive and market overlap. Compare multiple stocks →

Download Financial Ratios Data

Includes 30+ ratios · 11 years · Updated daily

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MNPR — Frequently Asked Questions

Quick answers to the most common questions about buying MNPR stock.

What is Monopar Therapeutics Inc.'s P/E ratio?

Monopar Therapeutics Inc.'s current P/E ratio is -44.2x. This places it at the 50th percentile of its historical range.

What is Monopar Therapeutics Inc.'s ROE?

Monopar Therapeutics Inc.'s return on equity (ROE) is -14.2%. The historical average is -68.9%.

Is MNPR stock overvalued?

Based on historical data, Monopar Therapeutics Inc. is trading at a P/E of -44.2x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.