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MNPRMonopar Therapeutics Inc.
$85.23$571M
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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MNPR logo

Monopar Therapeutics Inc.

MNPR
NASDAQ · Biotechnology
$85.23
At close - Sep 25, 4:00 PM EDT - USD
Market Cap$571M
P/E-46.1x
52W High$124.82
Volume105.82K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Pre-Revenue Clinical Burn Amidst Fortress Balance Sheet

Monopar Therapeutics is a clinical-stage biotech with zero revenue, whose operational trajectory is defined by accelerating R&D burn, as evidenced by Q2 2026 operating expenses of $6.6M against a cash position of $52.8M. The company's debt-free capital structu...

GrowthStable
ProfitabilityNegative
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

MNPR price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

8/12 Beats

EPS beat 8 of last 12 quarters

02

Valuation risk

-223% Peers

P/E is 223% below peer median

03

Market leadership

RS 75 · Avg

Average momentum (RS Rating: 75)

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystConfirmed earnings · Nov 12

Market performance

Price History →

Trailing total returns as of 9/26/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
MNPR+29.12%
S&P 500 (^GSPC)+12.91%
1-Year Return
MNPR+10.07%
S&P 500 (^GSPC)+17.22%
3-Year Return
MNPR+2819.01%
S&P 500 (^GSPC)+60.22%
5-Year Return
MNPR+238.91%
S&P 500 (^GSPC)+69.59%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$14M+12.0% YoY
Free cash flow
-$12M-90.5% YoY
Operating margin
-
ROIC (TTM)-29.4%
Avg ROIC 5Y-
ROE (TTM)-14.2%
Piotroski Score5 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate8/12 (67%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 12, 2026
-$0.62+3.6%
vs -$0.64
—
vs —
Q2 2026
May 14, 2026
-$0.46+56.6%
vs -$1.06
—
vs —
Q2 2026
Mar 27, 2026
-$0.61-19.1%
vs -$0.51
—
vs —
Q4 2025
Nov 13, 2025
-$0.48-4.3%
vs -$0.46
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·Aug 24, 2026
Monopar Therapeutics (NASDAQ:MNPR) and Regenicin (OTCMKTS:RGIN) Head-To-Head Contrast

Regenicin (OTCMKTS:RGIN - Get Free Report) and Monopar Therapeutics (NASDAQ: MNPR - Get Free Report) are both healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their analyst recommendations, profitability, earnings, dividends, valuation, risk and institutional ownership. Profitability This table compares Regenicin and Monopar Therapeutics' net

GlobeNewsWire·Aug 19, 2026
Monopar Appoints Jeffrey D. Kent, M.D.

WILMETTE, Ill., Aug. 19, 2026 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (“Monopar” or the “Company”) (Nasdaq: MNPR), a clinical-stage biopharmaceutical company developing innovative treatments for patients with unmet medical needs, today announced the appointment of Jeffrey D. Kent, M.D., FACP, FACG, as Executive Vice President, Head of Medical Affairs, effective September 1, 2026. The Company also announced that two abstracts on ALXN1840 (tiomolibdate choline, TMC), its late-stage candidate for the treatment of Wilson disease, have been accepted for presentation at the American Association for the Study of Liver Diseases (AASLD) – The Liver Meeting® 2026, taking place November 5-9, 2026, in Denver, Colorado.

Seeking Alpha·Aug 18, 2026
Monopar: Licensing Agreement And Rolling NDA Submission Serve As Catalysts For 'Strong Buy'

Monopar Therapeutics (MNPR) remains a "Strong Buy," driven by exclusive license rights to ALXN1840 for Wilson disease and ongoing radiotherapeutic development. Completion of the rolling NDA for ALXN1840 in the coming months is a major catalyst, with potential FDA approval and Priority Review Voucher upside. ALXN1840 demonstrated statistically significant efficacy in phase 3, showing 3x copper mobilization over placebo and notable neurological improvement versus standard of care.

247 Wallst·Aug 13, 2026
Here Are Thursday’s Top Wall Street Analyst Research Calls: Abbott Labs, AbbVie, Akamai Technologies, Five Below, Keurig Dr. Pepper, Salesforce, Stryker, StubHub, and More

Wall Street analysts made bold moves Thursday, slashing targets on some names while dramatically upgrading others, and the gap between winners and losers tells a story about where smart money is quietly repositioning ahead of the next market move.

Filtered for Monopar Therapeutics Inc.More Headlines
04

Compare before deciding

Benchmark MNPR against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Monopar Therapeutics Inc. (MNPR)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
MNPR logoMNPRMonopar Therapeutics Inc.Current
$85.24$570.99M-46.07——-14.22%—
CLDX logoCLDXCelldex Therapeutics, Inc.
$31.10$2.07B-7.97-78.63%-268385.71%-52.36%—
IMVT logoIMVTImmunovant, Inc.
$33.30$6.87B-12.02—-7585.86%-69.59%—
TPVG logoTPVGTriplePoint Venture Growth BDC Corp.
$4.83$196.09M3.9655.25%45.97%10.97%—
NKTR logoNKTRNektar Therapeutics
$57.06$1.89B-5.86-43.89%-287.84%-37.99%—
ADXN logoADXNAddex Therapeutics Ltd
$3.65$2.63M-0.44-92.58%-9388.51%-131.3%—

Compare MNPR vs Peers

Monopar Therapeutics Inc. (MNPR) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs CLDX

Most directly comparable listed peer for MNPR.

Scale Benchmark

vs IQV

Larger-name benchmark to compare MNPR against a more recognizable public peer.

Peer Set

Compare Top 5

vs CLDX, IMVT, TPVG, NKTR

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

MNPR SEC Filings & Documents

Monopar Therapeutics Inc. (MNPR) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 12, 2026·SEC

Material company update

Jul 22, 2026·SEC

Material company update

Jun 30, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 27, 2026·SEC

FY 2025

Mar 31, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 12, 2026·SEC

FY 2026

May 14, 2026·SEC

FY 2025

Nov 13, 2025·SEC

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MNPR Frequently Asked Questions

Monopar Therapeutics Inc. (MNPR) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is MNPR profitable?

Monopar Therapeutics Inc. (MNPR) reported a net loss of $17.8M for fiscal year 2025.

Dividend & Returns
What is MNPR's return on equity?

Monopar Therapeutics Inc. (MNPR) has a return on equity (ROE) of -14.2%. Negative ROE indicates the company is unprofitable.

What is Monopar Therapeutics Inc.'s free cash flow?

Monopar Therapeutics Inc. (MNPR) had negative free cash flow of $3.26B in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in MNPR back in 2015?

Total return calculator · dividends reinvested · 11+ years of data

See returns →