Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in NUVL held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) | 17.2M | $1.77B | 0.0% | 23.447% | 20.85% |
| 2 | FMR LLC | 9.3M | $950.2M | -14.5% | 12.608% | 0.05% |
| 3 | Paradigm Biocapital Advisors LP | 5.3M | $545.5M | +1.0% | 7.238% | 11.15% |
| 4 | BlackRock, Inc. | 4.8M | $494.3M | +0.4% | 6.559% | 0.01% |
| 5 | RA CAPITAL MANAGEMENT, L.P. | 2.5M | $259.6M | +34.8% | 3.445% | 2.75% |
| 6 | VANGUARD PORTFOLIO MANAGEMENT LLC | 2.5M | $256.2M | — | 3.400% | 0.01% |
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 2.5M | $253.1M | +0.4% | 3.358% | 0.05% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | 2.4M | $248.8M | — | 3.301% | 0.01% |
| 9 | STATE STREET CORP | 2.0M | $208.6M | +9.2% | 2.768% | 0.01% |
| 10 | Polar Capital Holdings Plc | 1.8M | $187.6M | +19.2% | 2.489% | 0.67% |
| 11 | PERCEPTIVE ADVISORS LLC | 1.6M | $161.9M | -5.1% | 2.148% | 3.20% |
| 12 | Deep Track Capital, LP | 1.4M | $141.0M | — | 1.871% | 2.91% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $133.0M | +4.8% | 1.765% | 0.01% |
| 14 | JANUS HENDERSON GROUP PLC | 1.2M | $126.8M | -17.5% | 1.683% | 0.06% |
| 15 | Bellevue Group AG | 1.1M | $107.9M | +1.5% | 1.432% | 2.57% |
| 16 | COMMODORE CAPITAL LP | 834K | $85.4M | +51.6% | 1.133% | 4.94% |
| 17 | ALLIANCEBERNSTEIN L.P. | 784K | $78.9M | -0.2% | 1.066% | 0.03% |
| 18 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 749K | $76.7M | +16.5% | 1.018% | 0.12% |
| 19 | BRAIDWELL LP | 700K | $71.8M | -14.7% | 0.952% | 2.39% |
| 20 | Woodline Partners LP | 610K | $62.5M | 0.0% | 0.830% | 0.24% |
| 21 | AMERIPRISE FINANCIAL INC | 564K | $57.8M | -0.1% | 0.766% | 0.01% |
| 22 | GOLDMAN SACHS GROUP INC | 537K | $55.0M | -9.6% | 0.730% | 0.01% |
| 23 | Vestal Point Capital, LP | 482K | $49.4M | +947.2% | 0.655% | 1.38% |
| 24 | DRIEHAUS CAPITAL MANAGEMENT LLC | 481K | $49.3M | -0.5% | 0.654% | 0.36% |
| 25 | Hood River Capital Management LLC | 480K | $49.2M | +1.0% | 0.653% | 0.49% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NUVL — a direct measure of their conviction.
Filings activity in NUVL during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 256 | +10% | 83.85% | 0.30 pp | $7.60B | 0.3% |
| Q4 2025 | 232 | +19% | 84.15% | +17.76 pp | $7.63B | +27% |
| Q3 2025 | 195 | 6.3% | 66.39% | +8.44 pp | $6.02B | +15% |
| Q2 2025 | 208 | +1.5% | 57.95% | +3.42 pp | $5.25B | +6.3% |
| Q1 2025 | 205 | 4.2% | 54.53% | 5.00 pp | $4.94B | 8.4% |
| Q4 2024 | 214 | +12% | 59.53% | 17.86 pp | $5.40B | 23% |
| Q3 2024 | 191 | +11% | 77.39% | +23.11 pp | $7.02B | +43% |
| Q2 2024 | 172 | — | 54.28% | — | $4.92B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NUVL stock.
Based on Q1 2026 13F filings, institutional ownership of Nuvalent, Inc. stands at 83.9%, held across 256 reporting institutions.
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) is the largest reported institutional holder of NUVL, with approximately 17,248,450 shares worth $1.77B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of NUVL.
Our composite Smart Money Score for NUVL is 36 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
55 institutions opened new positions in NUVL during Q1 2026, while 31 fully exited. 145 added to existing positions and 54 trimmed.
NUVL institutional ownership fell by 0.30 percentage points quarter-over-quarter, with a net change of +24 holders.
The top 10 institutions account for 68.0% of all reported 13F value in NUVL, and the top 25 account for 85.2%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Nuvalent, Inc. (NUVL) Institutional Ownership